Apolipoprotein B (Q648343)

Vitellinogen, beta-sheet N-terminal

1 reference

Lipovitellin-phosvitin complex, superhelical domain

1 reference

Lipid transport protein, beta-sheet shell

1 reference

Lipid transport protein, N-terminal domain, protein family

1 reference

Lipid transport, open beta-sheet, protein family

1 reference

Vitellinogen, open beta-sheet, protein family

1 reference

Apolipoprotein B100 C-terminal domain, protein family

1 reference

1 reference

13 November 2019

1 reference

13 November 2019

8 references

8 April 2019

Novel missense MTTP gene mutations causing abetalipoproteinemia

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04114

8 April 2019

Novel Abetalipoproteinemia Missense Mutation Highlights the Importance of the N-Terminal β-Barrel in Microsomal Triglyceride Transfer Protein Function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04114

8 April 2019

TANGO1 and Mia2/cTAGE5 (TALI) cooperate to export bulky pre-chylomicrons/VLDLs from the endoplasmic reticulum

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04114

8 April 2019

Proprotein convertase subtilisin/kexin type 9 interacts with apolipoprotein B and prevents its intracellular degradation, irrespective of the low-density lipoprotein receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04114

8 April 2019

LDL receptor/lipoprotein recognition: endosomal weakening of ApoB and ApoE binding to the convex face of the LR5 repeat

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04114

8 April 2019

A physical interaction network of dengue virus and human proteins

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04114

8 April 2019

Identification of disulfide-linked apolipoprotein species in human lipoproteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04114

8 April 2019

Hepatitis C virus nonstructural proteins inhibit apolipoprotein B100 secretion

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04114

lipid binding

1 reference

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04114&geneProductId=UniProtKB:P04114

lipid transporter activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04114

1 reference

8 April 2019

cholesterol transfer activity

1 reference

8 April 2019

Mutation in apolipoprotein B associated with hypobetalipoproteinemia despite decreased binding to the low density lipoprotein receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04114

lipase binding

1 reference

8 April 2019

Interaction between ApoB and Hepatic Lipase Mediates the Uptake of ApoB-containing Lipoproteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04114

low-density lipoprotein particle receptor binding

phospholipid binding

1 reference

8 April 2019

Sulfhydryl chemistry and solubility properties of human plasma apolipoprotein B

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04114

signaling receptor binding

1 reference

8 April 2019

TREM2 Binds to Apolipoproteins, Including APOE and CLU/APOJ, and Thereby Facilitates Uptake of Amyloid-Beta by Microglia.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04114

cell component

early endosome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04114

1 reference

8 April 2019

chylomicron remnant

1 reference

8 April 2019

Plasma lipoproteins: apolipoprotein structure and function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04114

vesicle lumen

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04114

endoplasmic reticulum

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04114

endosome membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04114

1 reference

8 April 2019

mature chylomicron

1 reference

8 April 2019

Assay of total plasma apolipoprotein B concentration in human subjects

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04114

endoplasmic reticulum lumen

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04114

1 reference

8 April 2019

vesicle membrane

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04114

endosome lumen

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04114

1 reference

8 April 2019

intermediate-density lipoprotein particle

1 reference

8 April 2019

Mechanisms of inhibition by apolipoprotein C of apolipoprotein E-dependent cellular metabolism of human triglyceride-rich lipoproteins through the low density lipoprotein receptor pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04114

clathrin-coated endocytic vesicle membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04114

1 reference

8 April 2019

endoplasmic reticulum membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04114

1 reference

8 April 2019

extracellular exosome

1 reference

17 October 2017

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04114&geneProductId=UniProtKB:P04114

endocytic vesicle lumen

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04114

1 reference

8 April 2019

soma

1 reference

8 April 2019

Apolipoprotein B is a new target of the GDNF/RET and ET-3/EDNRB signalling pathways

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04114

chylomicron

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04114

3 references

8 April 2019

8 April 2019

Identification of disulfide-linked apolipoprotein species in human lipoproteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04114

8 April 2019

Assay of total plasma apolipoprotein B concentration in human subjects

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04114

very-low-density lipoprotein particle

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04114&geneProductId=UniProtKB:P04114

4 references

1 January 2018

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04114&geneProductId=UniProtKB:P04114

1 January 2018

Overexpression of human diacylglycerol acyltransferase 1, acyl-coa:cholesterol acyltransferase 1, or acyl-CoA:cholesterol acyltransferase 2 stimulates secretion of apolipoprotein B-containing lipoproteins in McA-RH7777 cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04114&geneProductId=UniProtKB:P04114

1 January 2018

Assay of total plasma apolipoprotein B concentration in human subjects

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04114&geneProductId=UniProtKB:P04114

low-density lipoprotein particle

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04114&geneProductId=UniProtKB:P04114

3 references

1 January 2018

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04114&geneProductId=UniProtKB:P04114

1 January 2018

Assay of total plasma apolipoprotein B concentration in human subjects

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04114&geneProductId=UniProtKB:P04114

endoplasmic reticulum exit site

1 reference

8 April 2019

TANGO1 and Mia2/cTAGE5 (TALI) cooperate to export bulky pre-chylomicrons/VLDLs from the endoplasmic reticulum

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04114

smooth endoplasmic reticulum

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04114

1 reference

8 April 2019

plasma membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04114

1 reference

8 April 2019

lysosomal lumen

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04114

1 reference

8 April 2019

intracellular membrane-bounded organelle

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04114&geneProductId=UniProtKB:P04114

3 references

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04114&geneProductId=UniProtKB:P04114

17 October 2017

17 October 2017

Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veins

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04114&geneProductId=UniProtKB:P04114

extracellular region

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04114

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04114

8 April 2019

8 April 2019

Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04114

high-density lipoprotein particle

HDA

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04114

extracellular exosome

HDA

1 reference

8 April 2019

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04114

very-low-density lipoprotein particle

HDA

TREM2 Binds to Apolipoproteins, Including APOE and CLU/APOJ, and Thereby Facilitates Uptake of Amyloid-Beta by Microglia.

5 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04114

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04114

8 April 2019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04114

8 April 2019

Assay of total plasma apolipoprotein B concentration in human subjects

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04114

8 April 2019

Overexpression of human diacylglycerol acyltransferase 1, acyl-coa:cholesterol acyltransferase 1, or acyl-CoA:cholesterol acyltransferase 2 stimulates secretion of apolipoprotein B-containing lipoproteins in McA-RH7777 cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04114

low-density lipoprotein particle

TREM2 Binds to Apolipoproteins, Including APOE and CLU/APOJ, and Thereby Facilitates Uptake of Amyloid-Beta by Microglia.

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04114

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04114

8 April 2019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04114

8 April 2019

Assay of total plasma apolipoprotein B concentration in human subjects

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04114

biological process

artery morphogenesis

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04114

in utero embryonic development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04114

fertilization

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04114

receptor-mediated endocytosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04114

1 reference

8 April 2019

positive regulation of cholesterol storage

1 reference

8 April 2019

Chlamydia pneumoniae induces macrophage-derived foam cell formation via PPAR alpha and PPAR gamma-dependent pathways

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04114

regulation of cholesterol biosynthetic process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04114

nervous system development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04114

leukocyte migration

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04114

1 reference

8 April 2019

response to carbohydrate

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04114

retinoid metabolic process

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04114

1 reference

8 April 2019

steroid metabolic process

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04114

1 reference

8 April 2019

triglyceride mobilization

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04114

lipid catabolic process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04114

response to lipopolysaccharide

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04114

positive regulation of macrophage derived foam cell differentiation

3 references

8 April 2019

C-reactive protein-bound enzymatically modified low-density lipoprotein does not transform macrophages into foam cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04114

8 April 2019

Chlamydia pneumoniae induces macrophage-derived foam cell formation via PPAR alpha and PPAR gamma-dependent pathways

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04114

8 April 2019

Induction of dendritic cell-like phenotype in macrophages during foam cell formation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04114

cellular response to prostaglandin stimulus

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04114

response to virus

IEP

1 reference

8 April 2019

Transcriptomic and proteomic analyses of rhabdomyosarcoma cells reveal differential cellular gene expression in response to enterovirus 71 infection

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04114

positive regulation of lipid storage

IEP

1 reference

8 April 2019

C-reactive protein-bound enzymatically modified low-density lipoprotein does not transform macrophages into foam cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04114

cellular response to tumor necrosis factor

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04114

response to selenium ion

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04114

flagellated sperm motility

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04114

positive regulation of gene expression

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04114

response to organic substance

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04114

spermatogenesis

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04114

triglyceride catabolic process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04114

cholesterol efflux

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04114

post-embryonic development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04114

lipoprotein transport

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04114

toll-like receptor signaling pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04114

1 reference

8 April 2019

response to estradiol

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04114

membrane organization

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04114

1 reference

8 April 2019

chylomicron remodeling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04114

1 reference

8 April 2019

chylomicron assembly

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04114

1 reference

8 April 2019

very-low-density lipoprotein particle assembly

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04114

2 references

8 April 2019

8 April 2019

Overexpression of human diacylglycerol acyltransferase 1, acyl-coa:cholesterol acyltransferase 1, or acyl-CoA:cholesterol acyltransferase 2 stimulates secretion of apolipoprotein B-containing lipoproteins in McA-RH7777 cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04114

chylomicron remnant clearance

IC

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04114

1 reference

8 April 2019

low-density lipoprotein particle clearance

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04114

3 references

8 April 2019

8 April 2019

Mutation in apolipoprotein B associated with hypobetalipoproteinemia despite decreased binding to the low density lipoprotein receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04114

8 April 2019

Association between a specific apolipoprotein B mutation and familial defective apolipoprotein B-100

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04114

very-low-density lipoprotein particle clearance

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04114

1 reference

8 April 2019

lipoprotein metabolic process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04114

lipoprotein biosynthetic process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04114

lipoprotein catabolic process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04114

post-translational protein modification

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04114

1 reference

8 April 2019

transport

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04114&geneProductId=UniProtKB:P04114

1 reference

17 October 2017

http://purl.uniprot.org/uniprot/P04114

Gene Atlas image

PBB GE APOB 205108 s at fs.png
732 × 530; 8 KB

0 references

exact match

1 reference