Glyoxalase I (Q6469050)

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mammalian protein found in Homo sapiens

ketone-aldehyde mutase
GLO1
aldoketomutase
lactoyl glutathione lyase
glyoxalase domain containing 1
glx I
S-D-lactoylglutathione methylglyoxal lyase
epididymis secretory protein Li 74
methylglyoxalase
lactoylglutathione lyase

Language	Label	Description	Also known as
English	Glyoxalase I	mammalian protein found in Homo sapiens	ketone-aldehyde mutase GLO1 aldoketomutase lactoyl glutathione lyase glyoxalase domain containing 1 glx I S-D-lactoylglutathione methylglyoxal lyase epididymis secretory protein Li 74 methylglyoxalase lactoylglutathione lyase

Statements

1 reference

13 November 2019

UniProt protein ID

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q04760

Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q04760

Glyoxalase/fosfomycin resistance/dioxygenase domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Vicinal oxygen chelate (VOC) domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Glyoxalase I, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

lactoylglutathione lyase activity

determination method

6 references

8 April 2019

Human glyoxalase I. cDNA cloning, expression, and sequence similarity to glyoxalase I from Pseudomonas putida

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04760

determination method

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04760

determination method

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04760

determination method

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04760

determination method

8 April 2019

Selective activation of apoptosis program by S-p-bromobenzylglutathione cyclopentyl diester in glyoxalase I-overexpressing human lung cancer cells

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04760

determination method

8 April 2019

Involvement of an active-site Zn2+ ligand in the catalytic mechanism of human glyoxalase I

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04760

determination method

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04760

determination method

zinc ion binding

determination method

1 reference

8 April 2019

Involvement of an active-site Zn2+ ligand in the catalytic mechanism of human glyoxalase I

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04760

determination method

determination method

1 reference

8 April 2019

Proteomics of human umbilical vein endothelial cells applied to etoposide-induced apoptosis

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04760

determination method

extracellular exosome

determination method

3 references

26 September 2017

Proteomic analysis of podocyte exosome-enriched fraction from normal human urine

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q04760&geneProductId=UniProtKB:Q04760

determination method

26 September 2017

Large-scale proteomics and phosphoproteomics of urinary exosomes

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q04760&geneProductId=UniProtKB:Q04760

determination method

26 September 2017

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q04760&geneProductId=UniProtKB:Q04760

determination method

determination method

1 reference

8 April 2019

Human Protein Atlas

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04760

determination method

determination method

2 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04760

determination method

8 April 2019

Human Protein Atlas

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04760

determination method

plasma membrane

determination method

1 reference

8 April 2019

Human Protein Atlas

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04760

determination method

biological process

regulation of transcription by RNA polymerase II

determination method

1 reference

1 January 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04760

determination method

negative regulation of apoptotic process

determination method

3 references

8 April 2019

Proteomics of human umbilical vein endothelial cells applied to etoposide-induced apoptosis

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04760

determination method

8 April 2019

Glyoxalase I is involved in resistance of human leukemia cells to antitumor agent-induced apoptosis

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04760

determination method

8 April 2019

Selective activation of apoptosis program by S-p-bromobenzylglutathione cyclopentyl diester in glyoxalase I-overexpressing human lung cancer cells

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04760

determination method

methylglyoxal metabolic process

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04760

determination method

glutathione metabolic process

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04760

determination method

pyruvate metabolic process

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04760

determination method

osteoclast differentiation

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04760

determination method

Gene Atlas image

PBB GE GLO1 200681 at fs.png
732 × 530; 12 KB

0 references

Glyoxalase I, conserved site

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q04760

Glyoxalase/fosfomycin resistance/dioxygenase domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q04760

Vicinal oxygen chelate (VOC) domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q04760

Identifiers

RefSeq protein ID

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000362463

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000362463

PDB structure ID

1 reference

UniProt protein ID

5 August 2016

language of work or name

1 reference

UniProt protein ID

5 August 2016

language of work or name

1 reference

UniProt protein ID

5 August 2016

language of work or name

1 reference

UniProt protein ID

5 August 2016

language of work or name

1 reference

UniProt protein ID

5 August 2016

language of work or name

1 reference

UniProt protein ID

5 August 2016

language of work or name

1 reference

UniProt protein ID

5 August 2016

language of work or name

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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