A Requirement for the Rho-Family GTP Exchange Factor Vav in Positive and Negative Selection of Thymocytes (Q63408334)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9354466%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

title

A requirement for the Rho-family GTP exchange factor Vav in positive and negative selection of thymocytes (English)

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7 November 2019

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6

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7 November 2019

Victor Tybulewicz

7

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7 November 2019

author name string

M Turner

1

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7 November 2019

P J Mee

2

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7 November 2019

A E Walters

3

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7 November 2019

M E Quinn

4

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7 November 2019

A L Mellor

5

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7 November 2019

publication date

1 October 1997

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7 November 2019

language of work or name

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7 November 2019

volume

7

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7 November 2019

issue

4

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7 November 2019

page(s)

451-460

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Selective requirement for MAP kinase activation in thymocyte differentiation

7 November 2019

cites work

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https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980367-2

7 January 2021

Positive and negative selection invoke distinct signaling pathways.

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7 January 2021

Inositol trisphosphate and calcium signalling

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7 January 2021

Proto-vav and gene expression

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7 January 2021

Targeted expression of major histocompatibility complex (MHC) class II molecules demonstrates that dendritic cells can induce negative but not positive selection of thymocytes in vivo

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https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980367-2

7 January 2021

Product of vav proto-oncogene defines a new class of tyrosine protein kinase substrates

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7 January 2021

CD45-null transgenic mice reveal a positive regulatory role for CD45 in early thymocyte development, in the selection of CD4+CD8+ thymocytes, and B cell maturation

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7 January 2021

The small GTP-binding protein Rho regulates a phosphatidylinositol 4-phosphate 5-kinase in mammalian cells

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7 January 2021

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7 January 2021

The small GTP-binding proteins Rac1 and Cdc42 regulate the activity of the JNK/SAPK signaling pathway

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7 January 2021

Phosphotyrosine-dependent activation of Rac-1 GDP/GTP exchange by the vav proto-oncogene product

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7 January 2021

Negative selection by endogenous antigen and superantigen occurs at multiple thymic sites

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7 January 2021

Crucial role of the pre-T-cell receptor α gene in development of ap but not γδ T cells

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7 January 2021

Defective T-cell receptor signalling and positive selection of Vav-deficient CD4+ CD8+ thymocytes

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7 January 2021

An essential role for gp39, the ligand for CD40, in thymic selection.

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7 January 2021

Lck regulates Vav activation of members of the Rho family of GTPases

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7 January 2021

Thrombin receptor ligation and activated rac uncap actin filament barbed ends through phosphoinositide synthesis in permeabilized human platelets

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7 January 2021

Requirement for p56lck tyrosine kinase activation in T cell receptor-mediated thymic selection

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7 January 2021

Expression and function of the CD3-antigen receptor on murine CD4+8+ thymocytes

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7 January 2021

Both immature and mature T cells mobilize Ca2+ in response to antigen receptor crosslinking

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https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980367-2

7 January 2021

The thymus has two functionally distinct populations of immature alpha beta + T cells: one population is deleted by ligation of alpha beta TCR.

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7 January 2021

Signal transduction in T lymphocytes using a conditional allele of Sos

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7 January 2021

Positive selection of thymocytes

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https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980367-2

7 January 2021

Rac and Cdc42 induce actin polymerization and G1 cell cycle progression independently of p65PAK and the JNK/SAPK MAP kinase cascade

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7 January 2021

Functions of TCR and pre-TCR subunits: lessons from gene ablation

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7 January 2021

Positive and negative selection in transgenic mice expressing a T-cell receptor specific for influenza nucleoprotein and endogenous superantigen

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7 January 2021

Tyrosine phosphorylation of vav proto-oncogene product containing SH2 domain and transcription factor motifs

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7 January 2021

The staphylococcal enterotoxins and their relatives.

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7 January 2021

Selective activation of the JNK signaling cascadeand c-Jun transcriptional activity by the small GTPases Rac and Cdc42Hs

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https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980367-2

7 January 2021

In vivo calcium elevations in thymocytes with T cell receptors that are specific for self ligands

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7 January 2021

Essential role for ZAP-70 in both positive and negative selection of thymocytes

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https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980367-2

7 January 2021

Distinct sequence of negative or positive selection implied by thymocyte T-cell receptor densities

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7 January 2021

An Essential Role for Rho, Rac, and Cdc42 GTPases in Cell Cycle Progression Through G 1

1 reference

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7 January 2021

Faciogenital dysplasia protein (FGD1) and Vav, two related proteins required for normal embryonic development, are upstream regulators of Rho GTPases

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980367-2

7 January 2021

Raf regulates positive selection

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https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980367-2

7 January 2021

Physical association of the small GTPase Rho with a 68-kDa phosphatidylinositol 4-phosphate 5-kinase in Swiss 3T3 cells.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980367-2

7 January 2021

Crucial role of Jak3 in negative selection of self-reactive T cells.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980367-2

7 January 2021

T-cell receptor repertoire selection by mouse mammary tumor viruses and MHC molecules.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980367-2

7 January 2021

Functional immunoglobulin transgenes guide ordered B-cell differentiation in Rag-1-deficient mice

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7 January 2021

Induction of tolerance to self MHC class I molecules expressed under the control of milk protein or beta-globin gene promoters

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980367-2

7 January 2021

JNK is involved in signal integration during costimulation of T lymphocytes.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980367-2

7 January 2021

CD69 expression during selection and maturation of CD4+8+ thymocytes

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980367-2

7 January 2021

Activated Ras signals differentiation and expansion of CD4+8+ thymocytes

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980367-2

7 January 2021

A role for CD5 in TCR-mediated signal transduction and thymocyte selection

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980367-2

7 January 2021

Defective antigen receptor-mediated proliferation of B and T cells in the absence of Vav.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980367-2

7 January 2021

Tyrosine phosphorylation of the vav proto-oncogene product links FcepsilonRI to the Rac1-JNK pathway

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980367-2

7 January 2021

Rho Family GTPases Bind to Phosphoinositide Kinases

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980367-2

7 January 2021

Intracellular signals that mediate thymic negative selection

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https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980367-2

7 January 2021

T cell receptor-mediated signaling events in CD4+CD8+ thymocytes undergoing thymic selection: requirement of calcineurin activation for thymic positive selection but not negative selection.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980367-2

7 January 2021

The Vβ-specific superantigen staphylococcal enterotoxin B: Stimulation of mature T cells and clonal deletion in neonatal mice

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980367-2

7 January 2021

The agonist-antagonist balance in positive selection.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980367-2

7 January 2021

A functional T-cell receptor signaling pathway is required for p95vav activity

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https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980367-2

7 January 2021

CD69 cell surface expression identifies developing thymocytes which audition for T cell antigen receptor-mediated positive selection

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https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980367-2

7 January 2021

Defective signalling through the T- and B-cell antigen receptors in lymphoid cells lacking the vav proto-oncogene

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980367-2

7 January 2021

The vav proto-oncogene is required early in embryogenesis but not for hematopoietic development in vitro.

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https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980367-2

7 January 2021

10.1016/S1074-7613(00)80367-2

Identifiers

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7 November 2019

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