Toxicogenomic analysis of mainstream tobacco smoke-exposed mice reveals repression of plasminogen activator inhibitor-1 gene in heart (Q60476295)

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24 December 2019

title

Toxicogenomic analysis of mainstream tobacco smoke-exposed mice reveals repression of plasminogen activator inhibitor-1 gene in heart (English)

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24 December 2019

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24 December 2019

Carole Yauk

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24 December 2019

author name string

Lynn Berndt-Weis

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24 December 2019

Andrew Williams

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24 December 2019

George R Douglas

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24 December 2019

Sabina Halappanavar

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language of work or name

English

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publication date

1 January 2009

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24 December 2019

published in

Inhalation Toxicology

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24 December 2019

volume

21

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issue

1

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24 December 2019

page(s)

78-85

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Historical analysis of PAI-1 from its discovery to its potential role in cell motility and disease.

24 December 2019

cites work

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12 December 2020

Relationship between smoking and cardiovascular risk factors in the development of peripheral arterial disease and coronary artery disease; Edinburgh Artery Study Edinburgh Artery Study

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Improved statistical tests for differential gene expression by shrinking variance components estimates.

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12 December 2020

Downregulated expression of plasminogen activator inhibitor-1 augments myocardial neovascularization and reduces cardiomyocyte apoptosis after acute myocardial infarction

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12 December 2020

PAI-1 and atherothrombosis

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12 December 2020

Induction of oxidative stress and inhibition of plasminogen activator inhibitor-1 production in endothelial cells following exposure to organic extracts of diesel exhaust particles and urban fine particles

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Large scale real-time PCR validation on gene expression measurements from two commercial long-oligonucleotide microarrays

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Low PAI-1 activity in relation to the risk for perioperative bleeding complications in transurethral resection of the prostate.

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12 December 2020

Differential regulation of karyopherin alpha 2 expression by TGF-beta1 and IFN-gamma in normal human epidermal keratinocytes: evident contribution of KPNA2 for nuclear translocation of IRF-1

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12 December 2020

Mainstream tobacco smoke causes paternal germ-line DNA mutation

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12 December 2020

What is the clinical impact of low plasminogen activator inhibitor-1 (PAI-1) activity? A case report and study of the incidence of low PAI-1 antigen in a healthy population

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12 December 2020

AKAP12, a gene with tumour suppressor properties, is a target of promoter DNA methylation in childhood myeloid malignancies.

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12 December 2020

Polyphenols downregulate PAI-1 gene expression in cultured human coronary artery endothelial cells: molecular contributor to cardiovascular protection.

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Lipodystrophy in the fld mouse results from mutation of a new gene encoding a nuclear protein, lipin

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Normalization for cDNA microarray data: a robust composite method addressing single and multiple slide systematic variation

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Design considerations for efficient and effective microarray studies

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The structural basis for the pathophysiological relevance of PAI-I in cardiovascular diseases and the development of potential PAI-I inhibitors.

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The global smoking epidemic: a history and status report

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Penetration of the respiratory epithelium of guinea pigs following exposure to cigarette smoke

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The postoperative fibrinolytic shutdown: a rapidly reverting acute phase pattern for the fast-acting inhibitor of tissue-type plasminogen activator after trauma

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12 December 2020

Deficient t-PA release and elevated PA inhibitor levels in patients with spontaneous or recurrent deep venous thrombosis

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12 December 2020

Plasminogen activator inhibitor in plasma: risk factor for recurrent myocardial infarction

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12 December 2020

Type 1 plasminogen activator inhibitor

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12 December 2020

Regulation of murine type 1 plasminogen activator inhibitor gene expression in vivo. Tissue specificity and induction by lipopolysaccharide, tumor necrosis factor-alpha, and transforming growth factor-beta

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12 December 2020

Health effects of cigarette smoking

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12 December 2020

The acute effect of smoking on platelet and endothelial release reaction is suppressed in chronic smokers

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12 December 2020

Increased type 1 plasminogen activator inhibitor gene expression in atherosclerotic human arteries

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12 December 2020

Plasminogen activator inhibitor-1 gene-deficient mice. I. Generation by homologous recombination and characterization

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12 December 2020

Plasminogen activator inhibitor-1 gene-deficient mice. II. Effects on hemostasis, thrombosis, and thrombolysis

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12 December 2020

Induction of cytochrome CYPIA1 and formation of toxic metabolites of benzo[a]pyrene by rat aorta: a possible role in atherogenesis

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12 December 2020

Clinical Factors and Angiographic Features Associated With Premature Coronary Artery Disease

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12 December 2020

Smoking, serum lipids, blood pressure, and sex differences in myocardial infarction. A 12-year follow-up of the Finnmark Study

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12 December 2020

Identification of a cis-acting sequence in the human plasminogen activator inhibitor type-1 gene that mediates transforming growth factor-beta1 responsiveness in endothelium in vivo

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12 December 2020

Requirement for macrophage elastase for cigarette smoke-induced emphysema in mice

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12 December 2020

Endothelial dysfunction, impaired endogenous fibrinolysis, and cigarette smoking: a mechanism for arterial thrombosis and myocardial infarction

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12 December 2020

Molecular insight into the effects of hypothyroidism on the developing cerebellum.

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12 December 2020

10.1080/08958370802209165

Identifiers

DOI

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24 December 2019

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24 December 2019

PubMed publication ID

18925475

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