Molecular Biology of Aging (Q57175231)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9988222%20AND%20SRC:MED&resulttype=core&format=json

11 December 2019

title

Molecular biology of aging (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9988222%20AND%20SRC:MED&resulttype=core&format=json

11 December 2019

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F B Johnson

1

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11 December 2019

publication date

1 January 1999

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11 December 2019

language of work or name

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11 December 2019

volume

96

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9988222%20AND%20SRC:MED&resulttype=core&format=json

11 December 2019

issue

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9988222%20AND%20SRC:MED&resulttype=core&format=json

11 December 2019

page(s)

291-302

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9988222%20AND%20SRC:MED&resulttype=core&format=json

publication type of scholarly work

11 December 2019

review article

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Cell nonautonomy of C. elegans daf-2 function in the regulation of diapause and life span

cites work

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https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980567-X

7 January 2021

Some aspects of cell division in saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980567-X

7 January 2021

Telomere shortening and tumor formation by mouse cells lacking telomerase RNA

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980567-X

7 January 2021

Extension of life-span by introduction of telomerase into normal human cells

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980567-X

7 January 2021

Decline with age of the respiratory chain activity in human skeletal muscle.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980567-X

7 January 2021

DNA Repair and Transcription in Human Premature Aging Disorders

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980567-X

7 January 2021

Role of mitochondrial DNA mutations in human aging: Implications for the central nervous system and muscle

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980567-X

7 January 2021

Progeria: a human-disease model of accelerated aging

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980567-X

7 January 2021

The Role of Cellular Senescence in Skin Aging

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980567-X

7 January 2021

Telomere length and replicative aging in human vascular tissues

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980567-X

7 January 2021

Relationship between donor age and the replicative lifespan of human cells in culture: A reevaluation

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980567-X

7 January 2021

A biomarker that identifies senescent human cells in culture and in aging skin in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980567-X

7 January 2021

Rapid accumulation of genome rearrangements in liver but not in brain of old mice

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980567-X

7 January 2021

Replicative Senescence in the Immune System: Impact of the Hayflick Limit on T-Cell Function in the Elderly

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980567-X

7 January 2021

DNA helicases in inherited human disorders

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980567-X

7 January 2021

The Bloom's syndrome gene product is homologous to RecQ helicases

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980567-X

7 January 2021

Neurogenesis in the adult human hippocampus

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980567-X

7 January 2021

Structural and functional conservation of the Caenorhabditis elegans timing gene clk-1.

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https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980567-X

7 January 2021

The gene responsible for Werner syndrome may be a cell division "counting" gene

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980567-X

7 January 2021

The three faces of the WS helicase

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980567-X

7 January 2021

The yeast type I topoisomerase Top3 interacts with Sgs1, a DNA helicase homolog: a potential eukaryotic reverse gyrase

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980567-X

7 January 2021

Extrachromosomal circular DNAs and genomic sequence plasticity in eukaryotic cells

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980567-X

7 January 2021

Hierarchical deterioration of body systems in Werner's syndrome: Implications for normal ageing

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980567-X

7 January 2021

Food restriction eliminates preneoplastic cells through apoptosis and antagonizes carcinogenesis in rat liver

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980567-X

7 January 2021

The Werner syndrome protein is a DNA helicase

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980567-X

7 January 2021

Werner Helicase Is Localized to Transcriptionally Active Nucleoli of Cycling Cells

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https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980567-X

7 January 2021

Mitochondria and apoptosis

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https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980567-X

7 January 2021

In vivo human somatic mutation: frequency and spectrum with age

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https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980567-X

7 January 2021

Postmenopausal hormone therapy and mortality.

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https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980567-X

7 January 2021

Telomeres shorten during ageing of human fibroblasts

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https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980567-X

7 January 2021

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980567-X

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7 January 2021

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980567-X

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7 January 2021

Genetic control of programmed cell death and aging in the nematode Caenorhabditis elegans.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980567-X

7 January 2021

Mice deficient in cellular glutathione peroxidase develop normally and show no increased sensitivity to hyperoxia

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980567-X

7 January 2021

The genetics of aging in the yeast Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980567-X

7 January 2021

Telomerase expression in human somatic cells does not induce changes associated with a transformed phenotype

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980567-X

7 January 2021

Yeast Clk-1 Homologue (Coq7/Cat5) Is a Mitochondrial Protein in Coenzyme Q Synthesis

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980567-X

7 January 2021

Myocyte proliferation in end-stage cardiac failure in humans

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980567-X

7 January 2021

Mutation in the silencing gene S/R4 can delay aging in S. cerevisiae

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980567-X

7 January 2021

Redistribution of silencing proteins from telomeres to the nucleolus is associated with extension of life span in S. cerevisiae.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980567-X

7 January 2021

A C. elegans mutant that lives twice as long as wild type

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980567-X

7 January 2021

daf-2 , an Insulin Receptor-Like Gene That Regulates Longevity and Diapause in Caenorhabditis elegans

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980567-X

7 January 2021

An investigation of mutation as a function of age in humans.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980567-X

7 January 2021

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980567-X

1 reference

7 January 2021

Both Rb/p16INK4a inactivation and telomerase activity are required to immortalize human epithelial cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980567-X

7 January 2021

A method for the isolation of longevity mutants in the nematode Caenorhabditis elegans and initial results

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980567-X

7 January 2021

An age-associated correlation between cellular bioenergy decline and mtDNA rearrangements in human skeletal muscle

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980567-X

7 January 2021

Mutation of the mouse klotho gene leads to a syndrome resembling ageing

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980567-X

7 January 2021

The Endocrinology of Aging

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980567-X

7 January 2021

Aging and resistance to oxidative damage in Caenorhabditis elegans

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980567-X

7 January 2021

Age-associated alterations of the mitochondrial genome

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980567-X

7 January 2021

Essential role of mouse telomerase in highly proliferative organs

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980567-X

7 January 2021

daf-16: An HNF-3/forkhead family member that can function to double the life-span of Caenorhabditis elegans

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980567-X

7 January 2021

Extended Life-Span and Stress Resistance in the Drosophila Mutant methuselah

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980567-X

7 January 2021

Thermotolerance of a long-lived mutant of Caenorhabditis elegans

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980567-X

7 January 2021

Nucleolar localization of the Werner syndrome protein in human cells

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980567-X

7 January 2021

Increased frequency of deletions in the mitochondrial genome with age of Caenorhabditis elegans

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980567-X

7 January 2021

Marked increase in the number and variety of mitochondrial DNA rearrangements in aging human skeletal muscle

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980567-X

7 January 2021

A novel neurological phenotype in mice lacking mitochondrial manganese superoxide dismutase

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980567-X

7 January 2021

Absence of cancer-associated changes in human fibroblasts immortalized with telomerase

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980567-X

7 January 2021

A phosphatidylinositol-3-OH kinase family member regulating longevity and diapause in Caenorhabditis elegans

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980567-X

7 January 2021

Life and Death of Neurons in the Aging Brain

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980567-X

7 January 2021

Different in situ hybridization patterns of mitochondrial DNA in cytochrome c oxidase-deficient extraocular muscle fibres in the elderly

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980567-X

7 January 2021

The C. elegans PTEN homolog, DAF-18, acts in the insulin receptor-like metabolic signaling pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980567-X

7 January 2021

The Fork head transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C. elegans

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980567-X

7 January 2021

Gender differences and aging: effects on the human heart

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980567-X

7 January 2021

Extension of life-span by overexpression of superoxide dismutase and catalase in Drosophila melanogaster

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980567-X

7 January 2021

Regulation of c-fos expression in senescing Werner syndrome fibroblasts differs from that observed in senescing fibroblasts from normal donors

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980567-X

7 January 2021

Extension of Drosophila lifespan by overexpression of human SOD1 in motorneurons

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980567-X

7 January 2021

On size and survival: progress and pitfalls in the allometry of life span

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980567-X

7 January 2021

Motor neurons in Cu/Zn superoxide dismutase-deficient mice develop normally but exhibit enhanced cell death after axonal injury

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980567-X

7 January 2021

Morphologic changes accompanying senescence of cultured human diploid cells

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980567-X

7 January 2021

Evidence for a relationship between longevity of mammalian species and life spans of normal fibroblasts in vitro and erythrocytes in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980567-X

7 January 2021

ATM: from gene to function

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980567-X

7 January 2021

Effects of human growth hormone in men over 60 years old

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980567-X

7 January 2021

Causes, Effects, and Constraints in the Genetics of Human Longevity

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980567-X

7 January 2021

Accelerated loss of telomeric repeats may not explain accelerated replicative decline of Werner syndrome cells

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980567-X

7 January 2021

High levels of mitochondrial DNA deletions in skeletal muscle of old rhesus monkeys

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980567-X

7 January 2021

Distribution of wild-type and common deletion forms of mtDNA in normal and respiration-deficient muscle fibers from patients with mitochondrial myopathy

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980567-X

7 January 2021

Extrachromosomal rDNA circles--a cause of aging in yeast

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980567-X

7 January 2021

Accelerated Aging and Nucleolar Fragmentation in Yeast sgs1 Mutants

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980567-X

7 January 2021

Loss of transcriptional silencing causes sterility in old mother cells of S. cerevisiae

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980567-X

7 January 2021

Oxidative damage, mitochondrial oxidant generation and antioxidant defenses during aging and in response to food restriction in the mouse

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980567-X

7 January 2021

rqh1+, a fission yeast gene related to the Bloom's and Werner's syndrome genes, is required for reversible S phase arrest

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980567-X

7 January 2021

Genetic instability as the primary cause of human aging

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980567-X

7 January 2021

The Bloom's Syndrome Helicase Unwinds G4 DNA

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980567-X

7 January 2021

DNA helicase activity in Werner's syndrome gene product synthesized in a baculovirus system

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980567-X

7 January 2021

ON THE NATURE OF THE AGING PROCESS

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980567-X

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980567-X

7 January 2021

A comparative analysis of the proteins between the fibroblasts from Werner's syndrome patients and age-matched normal individuals using two-dimensional gel electrophoresis

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980567-X

7 January 2021

Reconstitution of telomerase activity in normal human cells leads to elongation of telomeres and extended replicative life span

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980567-X

7 January 2021

Bcl-2-deficient mice demonstrate fulminant lymphoid apoptosis, polycystic kidneys, and hypopigmented hair

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980567-X

7 January 2021

Full-term development of mice from enucleated oocytes injected with cumulus cell nuclei

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980567-X

7 January 2021

Mitochondrial biology, degenerative diseases and aging

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980567-X

7 January 2021

Sgs1: a eukaryotic homolog of E. coli RecQ that interacts with topoisomerase II in vivo and is required for faithful chromosome segregation

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980567-X

7 January 2021

What Does Cell Death Have To Do with Aging?

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980567-X

7 January 2021

The retardation of aging by caloric restriction: studies in rodents and primates

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980567-X

7 January 2021

Seminars in medicine of the Beth Israel Deaconess Medical Center. Caloric intake and aging

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980567-X

7 January 2021

Viable offspring derived from fetal and adult mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980567-X

7 January 2021

Replication focus-forming activity 1 and the Werner syndrome gene product

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980567-X

7 January 2021

Association of a polymorphic variant of the Werner helicase gene with myocardial infarction in a Japanese population

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980567-X

7 January 2021

Positional cloning of the Werner's syndrome gene

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980567-X

7 January 2021

10.1016/S0092-8674(00)80567-X

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9988222%20AND%20SRC:MED&resulttype=core&format=json

11 December 2019

1 reference