Mre11: roles in DNA repair beyond homologous recombination (Q55052114)

16 June 2018

title

Mre11: roles in DNA repair beyond homologous recombination (English)

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16 June 2018

1

Shan Zha

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16 June 2018

author name string

Cristian Boboila

series ordinal

2

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16 June 2018

Frederick W Alt

series ordinal

3

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16 June 2018

publication date

1 August 2009

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16 June 2018

Nature Structural & Molecular Biology

language of work or name

English

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published in

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16 June 2018

volume

16

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16 June 2018

issue

8

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16 June 2018

page(s)

798-800

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16 June 2018

Direct activation of the ATM protein kinase by the Mre11/Rad50/Nbs1 complex

cites work

1 reference

https://api.crossref.org/works/10.1038%2FNSMB0809-798

Ataxia-telangiectasia: from a rare disorder to a paradigm for cell signalling and cancer

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The cellular response to general and programmed DNA double strand breaks

31 March 2020

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H2AX prevents DNA breaks from progressing to chromosome breaks and translocations

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNSMB0809-798

Role of genomic instability and p53 in AID-induced c-myc-Igh translocations.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNSMB0809-798

ATM stabilizes DNA double-strand-break complexes during V(D)J recombination.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNSMB0809-798

Nbs1 potentiates ATP-driven DNA unwinding and endonuclease cleavage by the Mre11/Rad50 complex

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNSMB0809-798

The 3′ to 5′ Exonuclease Activity of Mre11 Facilitates Repair of DNA Double-Strand Breaks

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNSMB0809-798

The P. furiosus mre11/rad50 complex promotes 5' strand resection at a DNA double-strand break

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNSMB0809-798

Human CtIP promotes DNA end resection

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNSMB0809-798

Mre11 Dimers Coordinate DNA End Bridging and Nuclease Processing in Double-Strand-Break Repair

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNSMB0809-798

Mre11 protein complex prevents double-strand break accumulation during chromosomal DNA replication.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNSMB0809-798

Mre11 nuclease activity has essential roles in DNA repair and genomic stability distinct from ATM activation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNSMB0809-798

Roles for NBS1 in alternative nonhomologous end-joining of V(D)J recombination intermediates.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNSMB0809-798

MRN complex function in the repair of chromosomal Rag-mediated DNA double-strand breaks

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNSMB0809-798

Multiple functions of MRN in end-joining pathways during isotype class switching

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNSMB0809-798

Role of Mre11 in chromosomal nonhomologous end joining in mammalian cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNSMB0809-798

Role of mammalian Mre11 in classical and alternative nonhomologous end joining

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNSMB0809-798

Multiple roles for MRE11 at uncapped telomeres

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNSMB0809-798

MMEJ repair of double-strand breaks (director's cut): deleted sequences and alternative endings

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNSMB0809-798

DNA double-strand break repair: a relentless hunt uncovers new prey.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNSMB0809-798

XLF interacts with the XRCC4-DNA ligase IV complex to promote DNA nonhomologous end-joining

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNSMB0809-798

Cernunnos, a novel nonhomologous end-joining factor, is mutated in human immunodeficiency with microcephaly

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNSMB0809-798

Lymphocyte-specific compensation for XLF/cernunnos end-joining functions in V(D)J recombination

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNSMB0809-798

The role of the non-homologous end-joining pathway in lymphocyte development

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNSMB0809-798

Oncogenic transformation in the absence of Xrcc4 targets peripheral B cells that have undergone editing and switching

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNSMB0809-798

Unrepaired DNA breaks in p53-deficient cells lead to oncogenic gene amplification subsequent to translocations

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNSMB0809-798

Mechanisms promoting translocations in editing and switching peripheral B cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNSMB0809-798

Impact of the KU80 pathway on NHEJ-induced genome rearrangements in mammalian cells.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNSMB0809-798

Defects in XRCC4 and KU80 differentially affect the joining of distal nonhomologous ends

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNSMB0809-798

IgH class switching and translocations use a robust non-classical end-joining pathway

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNSMB0809-798

Role for DNA repair factor XRCC4 in immunoglobulin class switch recombination.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNSMB0809-798

A mechanistic basis for Mre11-directed DNA joining at microhomologies

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNSMB0809-798

Yeast Mre11 and Rad1 proteins define a Ku-independent mechanism to repair double-strand breaks lacking overlapping end sequences

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNSMB0809-798

Impairment of V(D)J recombination in double-strand break repair mutants

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNSMB0809-798

Rag mutations reveal robust alternative end joining

31 March 2020

2 references

https://api.crossref.org/works/10.1038%2FNSMB0809-798

31 March 2020

https://pubmed.ncbi.nlm.nih.gov/19654615

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

CtIP-BRCA1 modulates the choice of DNA double-strand-break repair pathway throughout the cell cycle.

1 reference

https://api.crossref.org/works/10.1038%2FNSMB0809-798

Nibrin functions in Ig class-switch recombination

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNSMB0809-798

Genomic instability, endoreduplication, and diminished Ig class-switch recombination in B cells lacking Nbs1.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNSMB0809-798

Impact of DNA ligase IV on nonhomologous end joining pathways during class switch recombination in human cells.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNSMB0809-798

MRE11/RAD50 cleaves DNA in the AID/UNG-dependent pathway of immunoglobulin gene diversification

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNSMB0809-798

How shelterin protects mammalian telomeres

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNSMB0809-798

Cell-cycle-regulated association of RAD50/MRE11/NBS1 with TRF2 and human telomeres

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNSMB0809-798

ERCC1/XPF removes the 3' overhang from uncapped telomeres and represses formation of telomeric DNA-containing double minute chromosomes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNSMB0809-798

31 March 2020

Identifiers

DOI

10.1038/NSMB0809-798

1 reference

16 June 2018

Dimensions Publication ID

1017148075

0 references

1 reference

16 June 2018