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Failure to cleave sterol regulatory element-binding proteins (SREBPs) causes cholesterol auxotrophy in Chinese hamster ovary cells with genetic absence of SREBP cleavage-activating protein (Q53436589)

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scientific article published in October 1999

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English	Failure to cleave sterol regulatory element-binding proteins (SREBPs) causes cholesterol auxotrophy in Chinese hamster ovary cells with genetic absence of SREBP cleavage-activating protein	scientific article published in October 1999

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scholarly article

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Europe PubMed Central

PubMed publication ID

14 May 2018

http://europepmc.org/abstract/MED/10497220

Failure to cleave sterol regulatory element-binding proteins (SREBPs) causes cholesterol auxotrophy in Chinese hamster ovary cells with genetic absence of SREBP cleavage-activating protein (English)

1 reference

Europe PubMed Central

PubMed publication ID

14 May 2018

http://europepmc.org/abstract/MED/10497220

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Joseph L. Goldstein

3

object named as

J L Goldstein

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Europe PubMed Central

PubMed publication ID

14 May 2018

http://europepmc.org/abstract/MED/10497220

author name string

R B Rawson

1

1 reference

Europe PubMed Central

PubMed publication ID

14 May 2018

http://europepmc.org/abstract/MED/10497220

R DeBose-Boyd

2

1 reference

Europe PubMed Central

PubMed publication ID

14 May 2018

http://europepmc.org/abstract/MED/10497220

M S Brown

4

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Europe PubMed Central

PubMed publication ID

14 May 2018

http://europepmc.org/abstract/MED/10497220

publication date

1 October 1999

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Europe PubMed Central

PubMed publication ID

14 May 2018

http://europepmc.org/abstract/MED/10497220

language of work or name

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Journal of Biological Chemistry

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Europe PubMed Central

PubMed publication ID

14 May 2018

http://europepmc.org/abstract/MED/10497220

274

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Europe PubMed Central

PubMed publication ID

14 May 2018

http://europepmc.org/abstract/MED/10497220

40

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Europe PubMed Central

PubMed publication ID

14 May 2018

http://europepmc.org/abstract/MED/10497220

28549-28556

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Europe PubMed Central

PubMed publication ID

14 May 2018

http://europepmc.org/abstract/MED/10497220

describes a project that uses

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The SREBP pathway: regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.40.28549

21 January 2018

Identification of Complexes between the COOH-terminal Domains of Sterol Regulatory Element-binding Proteins (SREBPs) and SREBP Cleavage-Activating Protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.40.28549

21 January 2018

Cleavage of sterol regulatory element-binding proteins (SREBPs) at site-1 requires interaction with SREBP cleavage-activating protein. Evidence from in vivo competition studies

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.40.28549

21 January 2018

Sterol resistance in CHO cells traced to point mutation in SREBP cleavage-activating protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.40.28549

21 January 2018

Topology of SREBP Cleavage-activating Protein, a Polytopic Membrane Protein with a Sterol-sensing Domain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.40.28549

21 January 2018

Chromatin, TAFs, and a novel multiprotein coactivator are required for synergistic activation by Sp1 and SREBP-1a in vitro

1 reference

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21 January 2018

A critical role for cAMP response element-binding protein (CREB) as a Co-activator in sterol-regulated transcription of 3-hydroxy-3-methylglutaryl coenzyme A synthase promoter

1 reference

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21 January 2018

Murine Model of Niemann-Pick C Disease: Mutation in a Cholesterol Homeostasis Gene

1 reference

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21 January 2018

Recurrent G-to-A substitution in a single codon of SREBP cleavage-activating protein causes sterol resistance in three mutant Chinese hamster ovary cell lines.

1 reference

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21 January 2018

The ancient regulatory-protein family of WD-repeat proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.40.28549

21 January 2018

Molecular identification of the sterol-regulated luminal protease that cleaves SREBPs and controls lipid composition of animal cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.40.28549

21 January 2018

Cleavage site for sterol-regulated protease localized to a leu-Ser bond in the lumenal loop of sterol regulatory element-binding protein-2.

1 reference

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21 January 2018

Complementation Cloning of , a Gene Encoding a Putative Metalloprotease Required for Intramembrane Cleavage of SREBPs

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.40.28549

21 January 2018

Sterol regulatory element-binding proteins: activators of cholesterol and fatty acid biosynthesis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.40.28549

21 January 2018

Isolation of Cholesterol-requiring Mutant Chinese Hamster Ovary Cells with Defects in Cleavage of Sterol Regulatory Element-binding Proteins at Site 1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.40.28549

21 January 2018

Somatic cell genetic and biochemical characterization of cell lines resulting from human genomic DNA transfections of Chinese hamster ovary cell mutants defective in sterol-dependent activation of sterol synthesis and LDL receptor expression

1 reference

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21 January 2018

Revertants of a Chinese hamster ovary cell mutant resistant to suppression by an analogue of cholesterol: isolation and partial biochemical characterization

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.40.28549

21 January 2018

Reconstituted low density lipoprotein: A vehicle for the delivery of hydrophobic fluorescent probes to cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.40.28549

21 January 2018

Regulated cleavage of sterol regulatory element binding proteins requires sequences on both sides of the endoplasmic reticulum membrane

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.40.28549

21 January 2018

Sterol-regulated release of SREBP-2 from cell membranes requires two sequential cleavages, one within a transmembrane segment

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.40.28549

21 January 2018

Three different rearrangements in a single intron truncate sterol regulatory element binding protein-2 and produce sterol-resistant phenotype in three cell lines. Role of introns in protein evolution

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.40.28549

21 January 2018

Autocatalytic processing of site-1 protease removes propeptide and permits cleavage of sterol regulatory element-binding proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.40.28549

21 January 2018

Differential Stimulation of Cholesterol and Unsaturated Fatty Acid Biosynthesis in Cells Expressing Individual Nuclear Sterol Regulatory Element-binding Proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.40.28549

21 January 2018

SREBP-1, a membrane-bound transcription factor released by sterol-regulated proteolysis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.40.28549

21 January 2018

Sterols regulate processing of carbohydrate chains of wild-type SREBP cleavage-activating protein (SCAP), but not sterol-resistant mutants Y298C or D443N.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.40.28549

21 January 2018

cDNA cloning and expression of the peptide-binding β subunit of rat p21rasfarnesyltransferase, the counterpart of yeast DPR1/RAM1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.40.28549

21 January 2018

A catalogue of splice junction sequences

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.40.28549

21 January 2018

19 Receptor-mediated endocytosis of low-density lipoprotein in cultured cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.40.28549

21 January 2018

Intracellular trafficking of cholesterol monitored with a cyclodextrin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.40.28549

21 January 2018

Protein measurement with the Folin phenol reagent

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.274.40.28549

Loss of transcriptional repression of three sterol-regulated genes in mutant hamster cells.

1 reference

19 October 2022

https://opencitations.net/index/coci/api/v1/citations/10.1016/S0021-9258(19)84879-2

Identifiers

10.1074/JBC.274.40.28549

1 reference

Europe PubMed Central

PubMed publication ID

14 May 2018

http://europepmc.org/abstract/MED/10497220

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

14 May 2018

http://europepmc.org/abstract/MED/10497220

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