Gonadotropin-releasing hormone receptor initiates multiple signaling pathways by exclusively coupling to G(q/11) proteins (Q52973183)

10 May 2018

title

Gonadotropin-releasing hormone receptor initiates multiple signaling pathways by exclusively coupling to G(q/11) proteins (English)

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author

Robert Grosse

1

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author name string

Schmid A

2

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Schöneberg T

3

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Herrlich A

4

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Muhn P

5

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Schultz G

6

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Gudermann T

7

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publication date

1 March 2000

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Journal of Biological Chemistry

language of work or name

English

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published in

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volume

275

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issue

13

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page(s)

9193-9200

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Studies of gonadotropin-releasing hormone (GnRH) action using GnRH receptor-expressing pituitary cell lines

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Inhibitory effects of analogs of luteinizing hormone-releasing hormone on the growth of the androgen-independent Dunning R-3327-AT-1 rat prostate cancer

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The nucleotide sequences of human GnRH receptors in breast and ovarian tumors are identical with that found in pituitary

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Identification of receptor-activated G proteins: selective immunoprecipitation of photolabeled G-protein alpha subunits

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Inhibition of Gonadotropin-Releasing Hormone Receptor Signaling by Expression of a Splice Variant of the Human Receptor

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Activation of MAP kinase by the LHRH receptor through a dual mechanism involving protein kinase C and a pertussis toxin-sensitive G protein

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Direct activation of human TRPC6 and TRPC3 channels by diacylglycerol

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Identification of a receptor/G-protein contact site critical for signaling specificity and G-protein activation

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Gonadotropin-Releasing Hormone Receptor Couples to Multiple G Proteins in Rat Gonadotrophs and in GGH3 Cells: Evidence from Palmitoylation and Overexpression of G proteins1

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Stable transfection of GH3 cells with rat gonadotropin-releasing hormone receptor complementary deoxyribonucleic acid results in expression of a receptor coupled to cyclic adenosine 3',5'-monophosphate-dependent prolactin release via a G-protein

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Diversity and selectivity of receptor-G protein interaction

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The Third Intracellular Loop of the Rat Gonadotropin-Releasing Hormone Receptor Couples the Receptor to Gs- and Gq/11-Mediated Signal Transduction Pathways: Evidence from Loop Fragment Transfection in GGH3 Cells*

21 January 2018

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Cell Lines of the Pituitary Gonadotrope Lineage Derived by Targeted Oncogenesis in Transgenic Mice

21 January 2018

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Intracellular Responses to Gonadotropin-Releasing Hormone in a Clonal Cell Line of the Gonadotrope Lineage

21 January 2018

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Estradiol regulates gonadotropin-releasing hormone receptor number, growth and inositol phosphate production in alpha T3-1 cells

21 January 2018

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Regulation of phosphoinositide-specific phospholipase C isozymes

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Gonadotrophin-releasing hormone receptor agonist-mediated down-regulation of Gq alpha/G11 alpha (pertussis toxin-insensitive) G proteins in alpha T3-1 gonadotroph cells reflects increased G protein turnover but not alterations in mRNA levels

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GnRH and PACAP action in gonadotropes: cross-talk between phosphoinositidase C and adenylyl cyclase mediated signaling pathways

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Cyclic AMP stimulates luteinizing-hormone (lutropin) exocytosis in permeabilized sheep anterior-pituitary cells. Synergism with protein kinase C and calcium

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G proteins of the Gq family couple the H2 histamine receptor to phospholipase C.

21 January 2018

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First intracellular loop of the human cholecystokinin-A receptor is essential for cyclic AMP signaling in transfected HEK-293 cells

21 January 2018

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Rat gonadotropin-releasing hormone receptor expressed in insect cells induces activation of adenylyl cyclase

21 January 2018

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Gonadotropin-releasing Hormone Receptors with Intracellular Carboxyl-terminal Tails Undergo Acute Desensitization of Total Inositol Phosphate Production and Exhibit Accelerated Internalization Kinetics

21 January 2018

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Differences in Structure–Function Relations between Nonmammalian and Mammalian Gonadotropin-Releasing Hormone Receptors

21 January 2018

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Functional and structural complexity of signal transduction via G-protein-coupled receptors

21 January 2018

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Regulation of Gq/11 by the Gonadotropin-Releasing Hormone Receptor

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.275.13.9193

1 reference

10 May 2018

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10 May 2018