Developmental regulation of V(D)J recombination at the TCR alpha/delta locus (Q52181531)

26 April 2018

title

Developmental regulation of V(D)J recombination at the TCR alpha/delta locus (English)

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26 April 2018

author

Pilar Lauzurica

3

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26 April 2018

author name string

Krangel MS

1

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26 April 2018

Hernandez-Munain C

2

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26 April 2018

McMurry M

4

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26 April 2018

Roberts JL

5

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26 April 2018

Zhong XP

6

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26 April 2018

publication date

1 October 1998

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26 April 2018

language of work or name

English

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published in

Immunological Reviews

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26 April 2018

volume

165

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26 April 2018

page(s)

131-147

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26 April 2018

publication type of scholarly work

review article

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Organization, structure, and function of 95 kb of DNA spanning the murine T-cell receptor C alpha/C delta region.

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Organization of the V gene segments in mouse T-cell antigen receptor alpha/delta locus.

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CD4 expressed on earliest T-lineage precursor cells in the adult murine thymus

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Two waves of recombinase gene expression in developing thymocytes

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T cell receptor delta gene rearrangement and T early alpha (TEA) expression in immature alpha beta lineage thymocytes: implications for alpha beta/gamma delta lineage commitment.

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Diversity and organization of human T cell receptor delta variable gene segments

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In-frame TCR delta gene rearrangements play a critical role in the alpha beta/gamma delta T cell lineage decision

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V-D-J rearrangements at the T cell receptor σ locus in mouse thymocytes of the αβ lineage

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Characterization of excised DNA intermediates associated with V(D)J recombination at the T-cell receptor delta locus

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The adult T-cell receptor delta-chain is diverse and distinct from that of fetal thymocytes

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A distinct wave of human T cell receptor gamma/delta lymphocytes in the early fetal thymus: evidence for controlled gene rearrangement and cytokine production

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Developmentally ordered appearance of thymocytes expressing different T-cell antigen receptors

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Multiple rearrangements in T cell receptor alpha chain genes maximize the production of useful thymocytes

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Exclusion and inclusion of α and β T cell receptor alleles

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Separate lineages of T cells expressing the alpha beta and gamma delta receptors

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Alpha beta and gamma delta T cells can share a late common precursor

21 January 2018

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Self-reactive gamma delta T cells are eliminated in the thymus

21 January 2018

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Intrathymic delta selection events in gammadelta cell development.

21 January 2018

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Notch activity influences the alphabeta versus gammadelta T cell lineage decision

21 January 2018

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The alpha beta T cell receptor can replace the gamma delta receptor in the development of gamma delta lineage cells

21 January 2018

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Events that regulate differentiation of alpha beta TCR+ and gamma delta TCR+ T cells from a common precursor.

21 January 2018

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DNA double-strand break repair and V(D)J recombination: involvement of DNA-PK.

21 January 2018

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Accessibility control of antigen-receptor variable-region gene assembly: role of cis-acting elements

21 January 2018

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Accessibility and the developmental regulation of V(D)J recombination

21 January 2018

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Cell type-specific chromatin structure determines the targeting of V(D)J recombinase activity in vitro

21 January 2018

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Enhancer-dependent and -independent steps in the rearrangement of a human T cell receptor delta transgene.

21 January 2018

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Gene-targeted deletion and replacement mutations of the T-cell receptor beta-chain enhancer: the role of enhancer elements in controlling V(D)J recombination accessibility.

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01236.X

Deletion of the mouse T-cell receptor beta gene enhancer blocks alphabeta T-cell development

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01236.X

Deletion of the Ig kappa light chain intronic enhancer/matrix attachment region impairs but does not abolish V kappa J kappa rearrangement

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01236.X

Temporal and lineage-specific control of T cell receptor alpha/delta gene rearrangement by T cell receptor alpha and delta enhancers

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01236.X

The polyomavirus enhancer activates chromatin accessibility on integration into the HPRT gene

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01236.X

Developmentally controlled and tissue-specific expression of unrearranged VH gene segments

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01236.X

Transcription of germ line V alpha segments correlates with ongoing T-cell receptor alpha-chain rearrangement

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01236.X

Ordered rearrangement of variable region genes of the T cell receptor gamma locus correlates with transcription of the unrearranged genes.

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01236.X

Differential activation of transcription versus recombination of transgenic T cell receptor beta variable region gene segments in B and T lineage cells

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01236.X

The V(D)J recombinational and transcriptional activities of the immunoglobulin heavy-chain intronic enhancer can be mediated through distinct protein-binding sites in a transgenic substrate

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01236.X

Influence of CpG methylation and target spacing on V(D)J recombination in a transgenic substrate

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01236.X

Targeting chromatin disruption: Transcription regulators that acetylate histones

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01236.X

Histone acetylation in chromatin structure and transcription

21 January 2018

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Tetrahymena histone acetyltransferase A: a homolog to yeast Gcn5p linking histone acetylation to gene activation

21 January 2018

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The transcriptional coactivators p300 and CBP are histone acetyltransferases

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01236.X

The CBP co-activator is a histone acetyltransferase

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01236.X

A p300/CBP-associated factor that competes with the adenoviral oncoprotein E1A

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01236.X

The TAF(II)250 subunit of TFIID has histone acetyltransferase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01236.X

A targeted mutation at the T-cell receptor alpha/delta locus impairs T-cell development and reveals the presence of the nearby antiapoptosis gene Dad1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01236.X

Regulation of transcription of the human T cell antigen receptor delta chain gene. A T lineage-specific enhancer element is located in the J delta 3-C delta intron

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01236.X

An enhancer-blocking element between alpha and delta gene segments within the human T cell receptor alpha/delta locus

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01236.X

Alpha beta lineage-specific expression of the alpha T cell receptor gene by nearby silencers

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01236.X

A locus control region in the T cell receptor alpha/delta locus

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01236.X

Cloning of GT box-binding proteins: a novel Sp1 multigene family regulating T-cell receptor gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01236.X

A delta T-cell receptor deleting element transgenic reporter construct is rearranged in alpha beta but not gamma delta T-cell lineages

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01236.X

Identification of a DNA segment exhibiting rearrangement modifying effects upon transgenic delta-deleting elements

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01236.X

Defect in rearrangement of the most 5' TCR-J alpha following targeted deletion of T early alpha (TEA): implications for TCR alpha locus accessibility

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01236.X

Adjacent DNA elements dominantly restrict the ubiquitous activity of a novel chromatin-opening region to specific tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01236.X

Enhancer control of local accessibility to V(D)J recombinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01236.X

Molecular analysis of V(D)J recombination

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01236.X

Initiation of V(D)J recombination in vitro obeying the 12/23 rule

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01236.X

The RAG1 and RAG2 proteins establish the 12/23 rule in V(D)J recombination

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01236.X

Initiation of V(D)J recombination in vivo: role of recombination signal sequences in formation of single and paired double-strand breaks

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01236.X

Developmental regulation of VDJ recombination by the core fragment of the T cell receptor alpha enhancer

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01236.X

Cooperation among Multiple Transcription Factors Is Required for Access to Minimal T-Cell Receptor α-Enhancer Chromatin In Vivo

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01236.X

Increased T-cell apoptosis and terminal B-cell differentiation induced by inactivation of the Ets-1 proto-oncogene

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01236.X

Defective activation and survival of T cells lacking the Ets-1 transcription factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01236.X

Generation of a novel Fli-1 protein by gene targeting leads to a defect in thymus development and a delay in Friend virus-induced erythroleukemia

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01236.X

Cloning of murine TCF-1, a T cell-specific transcription factor interacting with functional motifs in the CD3-epsilon and T cell receptor alpha enhancers

21 January 2018

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Extensive alternative splicing and dual promoter usage generate Tcf-1 protein isoforms with differential transcription control properties

21 January 2018

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Redundant Regulation of T Cell Differentiation and TCRα Gene Expression by the Transcription Factors LEF-1 and TCF-1

21 January 2018

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Impaired fetal T cell development and perinatal lethality in mice lacking the cAMP response element binding protein

21 January 2018

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Cloning and characterization of subunits of the T-cell receptor and murine leukemia virus enhancer core-binding factor

21 January 2018

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Molecular cloning and characterization of PEBP2 beta, the heterodimeric partner of a novel Drosophila runt-related DNA binding protein PEBP2 alpha

21 January 2018

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AML1, AML2, and AML3, the human members of the runt domain gene-family: cDNA structure, expression, and chromosomal localization

21 January 2018

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Expression of the Runt domain-encoding PEBP2 alpha genes in T cells during thymic development

21 January 2018

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Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblasts

21 January 2018

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Cbfa1, a candidate gene for cleidocranial dysplasia syndrome, is essential for osteoblast differentiation and bone development

21 January 2018

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AML1, the target of multiple chromosomal translocations in human leukemia, is essential for normal fetal liver hematopoiesis

21 January 2018

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Disruption of the Cbfa2 gene causes necrosis and hemorrhaging in the central nervous system and blocks definitive hematopoiesis

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01236.X

The CBFbeta subunit is essential for CBFalpha2 (AML1) function in vivo

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01236.X

Identification of an essential site for transcriptional activation within the human T-cell receptor delta enhancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01236.X

Indistinguishable nuclear factor binding to functional core sites of the T-cell receptor delta and murine leukemia virus enhancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01236.X

Regulation of the T-cell receptor delta enhancer by functional cooperation between c-Myb and core-binding factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01236.X

c-Myb and core-binding factor/PEBP2 display functional synergy but bind independently to adjacent sites in the T-cell receptor delta enhancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01236.X

Murine and human T-lymphocyte GATA-3 factors mediate transcription through a cis-regulatory element within the human T-cell receptor delta gene enhancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01236.X

Regulation of T cell receptor delta gene rearrangement by c-Myb

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01236.X

Regulation of T cell receptor delta gene rearrangement by CBF/PEBP2.

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01236.X

Expression of a proto-oncogene (proto-myb) in hemopoietic tissues of mice

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01236.X

A central role for a single c-Myb binding site in a thymic locus control region

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01236.X

A functional c-myb gene is required for normal murine fetal hepatic hematopoiesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01236.X

Transcription factor GATA-3 is required for development of the T-cell lineage

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01236.X

Boundary and insulator elements in chromosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01236.X

A position-effect assay for boundaries of higher order chromosomal domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01236.X

A group of scs elements function as domain boundaries in an enhancer-blocking assay

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01236.X

A 5' element of the chicken beta-globin domain serves as an insulator in human erythroid cells and protects against position effect in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01236.X

Modulation of enhancer-promoter interactions by insulators in the Drosophila embryo

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01236.X

The suppressor of Hairy-wing binding region is required for gypsy mutagenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01236.X

Characterization of the chicken beta-globin insulator

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01236.X

The enhancer-blocking suppressor of Hairy-wing zinc finger protein of Drosophila melanogaster alters DNA structure

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01236.X

Visualization of chromosomal domains with boundary element-associated factor BEAF-32.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01236.X

T cell receptor δ gene mutant mice: Independent generation of αβ T cells and programmed rearrangements of γδ TCR genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01236.X

Crucial role of the pre-T-cell receptor α gene in development of ap but not γδ T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01236.X

Differential expression of two distinct T-cell receptors during thymocyte development

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01236.X

Deletion of the human T-cell receptor δ-gene by a site-specific recombination

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01236.X

Recombination between immunoglobulin variable region gene segments is enhanced by transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01236.X

An HMG-box-containing T-cell factor required for thymocyte differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01236.X

T cell receptor beta chain gene rearrangement and selection during thymocyte development in adult mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01236.X

The Ig(kappa) enhancer influences the ratio of Ig(kappa) versus Ig(lambda) B lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01236.X

Activation of immunoglobulin kappa gene rearrangement correlates with induction of germline kappa gene transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01236.X

Function of the TCR alpha enhancer in alphabeta and gammadelta T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01236.X

10.1111/J.1600-065X.1998.TB01236.X

21 January 2018

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DOI

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26 April 2018

1 reference

26 April 2018