Suppression of glomerulonephritis in lupus-prone NZB × NZW mice by RN486, a selective inhibitor of Bruton's tyrosine kinase. (Q50919840)

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2 March 2020

title

Suppression of glomerulonephritis in lupus-prone NZB × NZW mice by RN486, a selective inhibitor of Bruton's tyrosine kinase (English)

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2 March 2020

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13

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2 March 2020

author name string

Paola Mina-Osorio

1

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2 March 2020

Jacob LaStant

2

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2 March 2020

Natalie Keirstead

3

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2 March 2020

Toni Whittard

4

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2 March 2020

Julia Ayala

5

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2 March 2020

Stella Stefanova

6

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2 March 2020

Rosario Garrido

7

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2 March 2020

Nena Dimaano

8

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2 March 2020

Holly Hilton

9

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2 March 2020

Mario Giron

10

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2 March 2020

Kai-Yeung Lau

11

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2 March 2020

Julie Hang

12

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2 March 2020

Yong Kim

14

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2 March 2020

Soo Min

15

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2 March 2020

Alka Patel

16

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2 March 2020

John Woods

17

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2 March 2020

Meera Ramanujam

18

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2 March 2020

Julie DeMartino

19

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2 March 2020

Satwant Narula

20

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2 March 2020

Daigen Xu

21

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2 March 2020

publication date

1 September 2013

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2 March 2020

published in

Arthritis and Rheumatism

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2 March 2020

volume

65

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2 March 2020

page(s)

2380-2391

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2 March 2020

issue

9

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Predictors of survival in systemic lupus erythematosus

2 March 2020

cites work

1 reference

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Defective B cell development and function in Btk-deficient mice

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Bruton's tyrosine kinase phosphorylates Toll-like receptor 3 to initiate antiviral response

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Impaired precursor B cell differentiation in Bruton's tyrosine kinase-deficient mice.

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RN486, a selective Bruton's tyrosine kinase inhibitor, abrogates immune hypersensitivity responses and arthritis in rodents

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Btk regulates localization, in vivo activation, and class switching of anti-DNA B cells

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A unique hybrid renal mononuclear phagocyte activation phenotype in murine systemic lupus erythematosus nephritis

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Predictive power of the second renal biopsy in lupus nephritis: significance of macrophages

21 January 2018

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Aberrant macrophages mediate defective kidney repair that triggers nephritis in lupus-susceptible mice

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The Bruton tyrosine kinase inhibitor PCI-32765 blocks B-cell activation and is efficacious in models of autoimmune disease and B-cell malignancy

21 January 2018

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Anti-tumor necrosis factor α treatment of interferon-α-induced murine lupus nephritis reduces the renal macrophage response but does not alter glomerular immune complex formation

21 January 2018

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21 January 2018

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Regulation of dendritic cell maturation and function by Bruton's tyrosine kinase via IL-10 and Stat3.

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Continuous administration of anti-interleukin 10 antibodies delays onset of autoimmunity in NZB/W F1 mice

21 January 2018

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Toll-like receptor 7 cooperates with IL-4 in activated B cells through antigen receptor or CD38 and induces class switch recombination and IgG1 production

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Serum from patients with SLE instructs monocytes to promote IgG and IgA plasmablast differentiation

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