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Aurora kinase B (Q4822491)

From Wikidata
mammalian protein found in Homo sapiens
  • serine/threonine kinase 12
  • AIM-1
  • serine/threonine-protein kinase aurora-B
  • STK-1
  • ARK-2
  • aurora- and Ipl1-like midbody-associated protein 1
  • aurora-B
  • aurora kinase B
  • aurora kinase B-Sv1
  • AURKB
  • serine/threonine-protein kinase 12
  • aurora kinase B-Sv2
  • aurora/IPL1-related kinase 2
  • protein phosphatase 1, regulatory subunit 48
  • serine/threonine-protein kinase 5
  • Aurora 1
  • aurora-1
  • aurora-related kinase 2
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    English
    Aurora kinase B
    mammalian protein found in Homo sapiens
    • serine/threonine kinase 12
    • AIM-1
    • serine/threonine-protein kinase aurora-B
    • STK-1
    • ARK-2
    • aurora- and Ipl1-like midbody-associated protein 1
    • aurora-B
    • aurora kinase B
    • aurora kinase B-Sv1
    • AURKB
    • serine/threonine-protein kinase 12
    • aurora kinase B-Sv2
    • aurora/IPL1-related kinase 2
    • protein phosphatase 1, regulatory subunit 48
    • serine/threonine-protein kinase 5
    • Aurora 1
    • aurora-1
    • aurora-related kinase 2

    Statements

    molecular function
    protein binding
    determination method or standard
    IPI
    28 references
    retrieved
    8 April 2019
    stated in
    Aurora B Interacts with NIR-p53, Leading to p53 Phosphorylation in Its DNA-binding Domain and Subsequent Functional Suppression
    GOA
    curator
    UniProt
    UniProt protein ID
    Q96GD4
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96GD4
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Molecular analysis of survivin isoforms: evidence that alternatively spliced variants do not play a role in mitosis
    GOA
    curator
    UniProt
    UniProt protein ID
    Q96GD4
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96GD4
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Phosphorylation by Aurora B Converts MgcRacGAP to a RhoGAP during Cytokinesis
    GOA
    curator
    UniProt
    UniProt protein ID
    Q96GD4
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96GD4
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Interphase nucleo-cytoplasmic shuttling and localization of SIRT2 during mitosis
    GOA
    curator
    UniProt
    UniProt protein ID
    Q96GD4
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96GD4
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    A novel big protein TPRBK possessing 25 units of TPR motif is essential for the progress of mitosis and cytokinesis
    GOA
    curator
    UniProt
    UniProt protein ID
    Q96GD4
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96GD4
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Mps1 phosphorylates Borealin to control Aurora B activity and chromosome alignment
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96GD4
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Aurora-C Interactions with Survivin and INCENP Reveal Shared and Distinct Features Compared with Aurora-B Chromosome Passenger Protein Complex
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96GD4
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Phosphorylation of the CPC by Cdk1 promotes chromosome bi-orientation
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96GD4
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Quantitative analysis of HSP90-client interactions reveals principles of substrate recognition
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96GD4
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    VRK1 and AURKB form a complex that cross inhibit their kinase activity and the phosphorylation of histone H3 in the progression of mitosis.
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96GD4
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Acetylation of Aurora B by TIP60 ensures accurate chromosomal segregation
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96GD4
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Aurora B -TACC1 protein complex in cytokinesis
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96GD4
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    A quantitative chaperone interaction network reveals the architecture of cellular protein homeostasis pathways
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96GD4
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    The GAR domain of GAS2L3 mediates binding to the chromosomal passenger complex and is required for localization of GAS2L3 to the constriction zone during abscission
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96GD4
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Spatio-temporal composition of the mitotic Chromosomal Passenger Complex detected using in situ proximity ligation assay
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96GD4
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Cell death in leukemia: passenger protein regulation by topoisomerase inhibitors
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96GD4
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Mitotic centromeric targeting of HP1 and its binding to Sgo1 are dispensable for sister-chromatid cohesion in human cells
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96GD4
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Phosphorylation of multifunctional nucleolar protein nucleophosmin (NPM1) by aurora kinase B is critical for mitotic progression
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96GD4
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    An AP-MS- and BioID-compatible MAC-tag enables comprehensive mapping of protein interactions and subcellular localizations
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96GD4
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    EB1 promotes Aurora-B kinase activity through blocking its inactivation by protein phosphatase 2A
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96GD4
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    The Survivin-Crm1 interaction is essential for chromosomal passenger complex localization and function
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96GD4
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Survivin mediates targeting of the chromosomal passenger complex to the centromere and midbody
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96GD4
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Structure of a Survivin-Borealin-INCENP core complex reveals how chromosomal passengers travel together
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96GD4
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Molecular analysis of survivin isoforms: evidence that alternatively spliced variants do not play a role in mitosis
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96GD4
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Septin1, a new interaction partner for human serine/threonine kinase aurora-B
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96GD4
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Toward an understanding of the protein interaction network of the human liver
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96GD4
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Human POGZ modulates dissociation of HP1alpha from mitotic chromosome arms through Aurora B activation
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96GD4
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    A single amino acid change converts Aurora-A into Aurora-B-like kinase in terms of partner specificity and cellular function
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96GD4
    determination method or standard
    IPI
    cell component
    chromosome passenger complex
    determination method or standard
    IBA
    IEA
    IPI
    TAS
    6 references
    retrieved
    8 April 2019
    stated in
    Aurora A, centrosome structure, and the centrosome cycle
    GOA
    curator
    UniProt
    UniProt protein ID
    Q96GD4
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96GD4
    determination method or standard
    TAS
    retrieved
    8 April 2019
    stated in
    A survivin-ran complex regulates spindle formation in tumor cells
    GOA
    curator
    UniProt
    UniProt protein ID
    Q96GD4
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96GD4
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    The chromosomal passenger complex is required for chromatin-induced microtubule stabilization and spindle assembly
    GOA
    curator
    UniProt
    UniProt protein ID
    Q96GD4
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96GD4
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    GOA
    curator
    InterPro
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96GD4
    determination method or standard
    IEA
    retrieved
    8 April 2019
    stated in
    GOA
    curator
    Ensembl genome database project
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96GD4
    determination method or standard
    IEA
    retrieved
    8 April 2019
    stated in
    Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
    GOA
    curator
    GO Central
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96GD4
    determination method or standard
    IBA
    biological process
    physically interacts with
    Gene Atlas image
    PBB GE AURKB 209464 at fs.png
    732 × 530; 11 KB
    0 references

    Identifiers

     
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