Bcl-2-family proteins: the role of the BH3 domain in apoptosis (Q47686942)

4 February 2018

title

Bcl-2-family proteins: the role of the BH3 domain in apoptosis (English)

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4 February 2018

main subject

BH4 domain binding

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A. Kelekar

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9704409

4 January 2025

C. B. Thompson

series ordinal

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9704409

4 January 2025

publication date

1 August 1998

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4 February 2018

August 1998

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National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=9704409

4 January 2025

language of work or name

English

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National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=9704409

https://api.elsevier.com/content/article/PII:S096289249801321X?httpAccept=text/xml

4 January 2025

work available at URL

1 reference

https://api.crossref.org/works/10.1016/S0962-8924(98)01321-X

https://api.elsevier.com/content/article/PII:S096289249801321X?httpAccept=text/plain

4 January 2025

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https://api.crossref.org/works/10.1016/S0962-8924(98)01321-X

4 January 2025

published in

Trends in Cell Biology

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4 February 2018

volume

8

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4 February 2018

issue

8

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4 February 2018

page(s)

324-330

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4 February 2018

publication type of scholarly work

review article

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The central executioners of apoptosis: caspases or mitochondria?

cites work

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7 January 2021

Cloning the chromosomal breakpoint of t(14;18) human lymphomas: clustering around JH on chromosome 14 and near a transcriptional unit on 18.

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7 January 2021

Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death

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7 January 2021

bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death

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7 January 2021

The E1B 19K protein blocks apoptosis by interacting with and inhibiting the p53-inducible and death-promoting Bax protein

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7 January 2021

Epstein-Barr virus-coded BHRF1 protein, a viral homologue of Bcl-2, protects human B cells from programmed cell death

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7 January 2021

C. elegans cell survival gene ced-9 encodes a functional homolog of the mammalian proto-oncogene bcl-2.

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7 January 2021

Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death

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7 January 2021

Induction of apoptosis by the Bcl-2 homologue Bak

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7 January 2021

Bcl-x(S) anatagonizes the protective effects of Bcl-x(L).

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7 January 2021

Bok is a pro-apoptotic Bcl-2 protein with restricted expression in reproductive tissues and heterodimerizes with selective anti-apoptotic Bcl-2 family members

1 reference

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7 January 2021

Mtd, a novel Bcl-2 family member activates apoptosis in the absence of heterodimerization with Bcl-2 and Bcl-XL

1 reference

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7 January 2021

Bad, a heterodimeric partner for Bcl-XL and Bcl-2, displaces Bax and promotes cell death

1 reference

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7 January 2021

BID: a novel BH3 domain-only death agonist

1 reference

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7 January 2021

Bim: a novel member of the Bcl-2 family that promotes apoptosis

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7 January 2021

harakiri, a novel regulator of cell death, encodes a protein that activates apoptosis and interacts selectively with survival-promoting proteins Bcl-2 and Bcl-X(L)

1 reference

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7 January 2021

Blk, a BH3-containing Mouse Protein That Interacts with Bcl-2 and Bcl-xL, Is a Potent Death Agonist

1 reference

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7 January 2021

X-ray and NMR structure of human Bcl-xL, an inhibitor of programmed cell death

1 reference

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7 January 2021

Identification of a novel regulatory domain in Bcl-X(L) and Bcl-2.

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7 January 2021

Conversion of Bcl-2 to a Bax-like Death Effector by Caspases

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7 January 2021

Suppression of signalling through transcription factor NF-AT by interactions between calcineurin and Bcl-2.

1 reference

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7 January 2021

The conserved N-terminal BH4 domain of Bcl-2 homologues is essential for inhibition of apoptosis and interaction with CED-4

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7 January 2021

Functional dissection of the human Bc12 protein: sequence requirements for inhibition of apoptosis

1 reference

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7 January 2021

Bcl-2 functions in an antioxidant pathway to prevent apoptosis

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7 January 2021

Cytosol-to-membrane redistribution of Bax and Bcl-X(L) during apoptosis

1 reference

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7 January 2021

Bcl-2 prolongs cell survival after Bax-induced release of cytochrome c

1 reference

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7 January 2021

Multiple Bcl-2 family members demonstrate selective dimerizations with Bax

1 reference

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7 January 2021

BH1 and BH2 domains of Bcl-2 are required for inhibition of apoptosis and heterodimerization with Bax.

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2898%2901321-X

7 January 2021

Structure of Bcl-xL-Bak peptide complex: recognition between regulators of apoptosis

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7 January 2021

The distal pathway of lipoprotein-induced cholesterol esterification, but not sphingomyelinase-induced cholesterol esterification, is energy-dependent.

1 reference

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7 January 2021

Bcl-x(L) forms an ion channel in synthetic lipid membranes

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7 January 2021

Comparison of the ion channel characteristics of proapoptotic BAX and antiapoptotic BCL-2

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7 January 2021

Channel formation by antiapoptotic protein Bcl-2.

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https://api.crossref.org/works/10.1016%2FS0962-8924%2898%2901321-X

7 January 2021

Inhibition of Bax channel-forming activity by Bcl-2

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https://api.crossref.org/works/10.1016%2FS0962-8924%2898%2901321-X

7 January 2021

Mitochondrial control of nuclear apoptosis.

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https://api.crossref.org/works/10.1016%2FS0962-8924%2898%2901321-X

7 January 2021

Mitochondrial permeability transition is a central coordinating event of apoptosis

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7 January 2021

The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis

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7 January 2021

Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked

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7 January 2021

Bcl-xL Regulates the Membrane Potential and Volume Homeostasis of Mitochondria

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7 January 2021

Bad Is a BH3 Domain-Containing Protein That Forms an Inactivating Dimer with Bcl-XL

1 reference

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7 January 2021

Functional dissection of the pro-apoptotic protein Bik. Heterodimerization with anti-apoptosis proteins is insufficient for induction of cell death

1 reference

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7 January 2021

Molecular Cloning of a Novel Polypeptide, DP5, Induced during Programmed Neuronal Death

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7 January 2021

Cytochrome c and dATP-Dependent Formation of Apaf-1/Caspase-9 Complex Initiates an Apoptotic Protease Cascade

1 reference

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7 January 2021

Interaction of CED-4 with CED-3 and CED-9: a molecular framework for cell death

1 reference

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7 January 2021

Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2898%2901321-X

7 January 2021

Interaction and regulation of subcellular localization of CED-4 by CED-9

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2898%2901321-X

7 January 2021

Caspase-9, Bcl-XL, and Apaf-1 Form a Ternary Complex

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2898%2901321-X

7 January 2021

Regulation of apoptosis by BH3 domains in a cell-free system

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2898%2901321-X

7 January 2021

Serine phosphorylation of death agonist BAD in response to survival factor results in binding to 14-3-3 not BCL-X(L)

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2898%2901321-X

7 January 2021

Akt Phosphorylation of BAD Couples Survival Signals to the Cell-Intrinsic Death Machinery

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7 January 2021

23

54

2468

Akao

1994

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https://api.crossref.org/works/10.1016/S0962-8924(98)01321-X

Targeting of Bcl-2 to the mitochondrial outer membrane by a COOH-terminal signal anchor sequence.

4 January 2025

series ordinal

33

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https://api.crossref.org/works/10.1016/S0962-8924(98)01321-X

4 January 2025

Identifiers

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4 February 2018

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4 February 2018