A SAXS-based ensemble model of the native and phosphorylated regulatory domain of the CFTR. (Q46491265)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23052212%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

title

A SAXS-based ensemble model of the native and phosphorylated regulatory domain of the CFTR (English)

1 reference

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10 March 2020

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3

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10 March 2020

author name string

Carlotta Marasini

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23052212%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

Lauretta Galeno

series ordinal

2

1 reference

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10 March 2020

publication date

4 October 2012

1 reference

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Cellular and Molecular Life Sciences

10 March 2020

language of work or name

English

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published in

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10 March 2020

volume

70

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10 March 2020

issue

5

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10 March 2020

page(s)

923-933

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Cystic fibrosis transmembrane conductance regulator: using differential reactivity toward channel-permeant and channel-impermeant thiol-reactive probes to test a molecular model for the pore

10 March 2020

cites work

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The gel-filtration behaviour of proteins related to their molecular weights over a wide range

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CFTR regulatory region interacts with NBD1 predominantly via multiple transient helices

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Structural analysis of intrinsically disordered proteins by small-angle X-ray scattering

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Structural characterization of flexible proteins using small-angle X-ray scattering

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Phosphorylation of CFTR by PKA promotes binding of the regulatory domain

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New model of cystic fibrosis transmembrane conductance regulator proposes active channel-like conformation.

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Intrinsically disordered protein

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Mutation of potential phosphorylation sites in the recombinant R domain of the cystic fibrosis transmembrane conductance regulator has significant effects on domain conformation

21 January 2018

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DAMMIF, a program for rapid ab-initio shape determination in small-angle scattering

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Computational studies reveal phosphorylation-dependent changes in the unstructured R domain of CFTR.

21 January 2018

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Prediction of disordered regions in proteins based on the meta approach

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NMR evidence for differential phosphorylation-dependent interactions in WT and DeltaF508 CFTR.

21 January 2018

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Automated matching of high- and low-resolution structural models

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Structure of nucleotide-binding domain 1 of the cystic fibrosis transmembrane conductance regulator

21 January 2018

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Thermodynamic study of the native and phosphorylated regulatory domain of the CFTR

21 January 2018

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Structural diversity in free and bound states of intrinsically disordered protein phosphatase 1 regulators

21 January 2018

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Atomic model of human cystic fibrosis transmembrane conductance regulator: membrane-spanning domains and coupling interfaces

21 January 2018

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Molecular models of the open and closed states of the whole human CFTR protein

21 January 2018

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Evidence for phosphorylation of serine 753 in CFTR using a novel metal‐ion affinity resin and matrix‐assisted laser desorption mass spectrometry

21 January 2018

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Cystic Fibrosis Transmembrane Conductance Regulator: A Molecular Model Defines the Architecture of the Anion Conduction Path and Locates a “Bottleneck” in the Pore

21 January 2018

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Regulation of the cystic fibrosis transmembrane conductance regulator Cl- channel by its R domain

21 January 2018

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The molten globule is a third thermodynamical state of protein molecules

21 January 2018

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Phenylalanine-508 mediates a cytoplasmic-membrane domain contact in the CFTR 3D structure crucial to assembly and channel function

21 January 2018

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Computation and analysis of protein circular dichroism spectra

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Small-angle scattering studies of biological macromolecules in solution

21 January 2018

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Biophysical constraints for protein structure prediction

21 January 2018

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Identification of protein kinase A phosphorylation sites on NBD1 and R domains of CFTR using electrospray mass spectrometry with selective phosphate ion monitoring

21 January 2018

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Natively unfolded proteins: a point where biology waits for physics

21 January 2018

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The cystic fibrosis transmembrane conductance regulator: an intriguing protein with pleiotropic functions

21 January 2018

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Protein secondary structure analyses from circular dichroism spectroscopy: methods and reference databases

21 January 2018

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Domain-domain associations in cystic fibrosis transmembrane conductance regulator

21 January 2018

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A short segment of the R domain of cystic fibrosis transmembrane conductance regulator contains channel stimulatory and inhibitory activities that are separable by sequence modification

21 January 2018

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Architecture of the cystic fibrosis transmembrane conductance regulator protein and structural changes associated with phosphorylation and nucleotide binding.

21 January 2018

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Domain location within the cystic fibrosis transmembrane conductance regulator protein investigated by electron microscopy and gold labelling

21 January 2018

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Why are "natively unfolded" proteins unstructured under physiologic conditions?

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23052212

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1007/S00018-012-1172-5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23052212%20AND%20SRC:MED&resulttype=core&format=json

release_bm4p37y53bad5icm2xk5ebrnti

10 March 2020

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/bm4p37y53bad5icm2xk5ebrnti

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference