Genomic instability in repeated sequences is an early somatic event in colorectal tumorigenesis that persists after transformation (Q46049171)

19 December 2017

title

Genomic instability in repeated sequences is an early somatic event in colorectal tumorigenesis that persists after transformation (English)

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19 December 2017

author

Miguel A. Peinado

2

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19 December 2017

Manuel Perucho

5

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19 December 2017

author name string

Shibata D

1

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19 December 2017

Ionov Y

3

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19 December 2017

Malkhosyan S

4

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19 December 2017

language of work or name

English

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publication date

1 March 1994

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19 December 2017

published in

Nature Genetics

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19 December 2017

volume

6

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19 December 2017

page(s)

273-281

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19 December 2017

issue

3

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19 December 2017

https://scigraph.springernature.com/pub.10.1038/ng0394-273

exact match

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cites work

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Frameshift mutations and the genetic code. This paper is dedicated to Professor Theodosius Dobzhansky on the occasion of his 66th birthday

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A poly(dA-dT) upstream activating sequence binds high-mobility group I protein and contributes to lymphotoxin (tumor necrosis factor-beta) gene regulation

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Prevalence of ras gene mutations in human colorectal cancers

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Detection of high incidence of K-ras oncogenes during human colon tumorigenesis

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Chromosome 17 deletions and p53 gene mutations in colorectal carcinomas

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Identification of a chromosome 18q gene that is altered in colorectal cancers

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Identification of FAP locus genes from chromosome 5q21

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Identification and characterization of the familial adenomatous polyposis coli gene

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A genetic model for colorectal tumorigenesis

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7 January 2021

Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis

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7 January 2021

Microsatellite instability in cancer of the proximal colon

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Clues to the pathogenesis of familial colorectal cancer

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An explicit hypothesis for chemical carcinogenesis

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Mutation selection and the natural history of cancer

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Genetic mapping of a locus predisposing to human colorectal cancer

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7 January 2021

Genetic mapping of a second locus predisposing to hereditary non–polyposis colon cancer

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7 January 2021

Isolation and characterization of allelic losses and gains in colorectal tumors by arbitrarily primed polymerase chain reaction

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7 January 2021

Mutation of human short tandem repeats

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7 January 2021

Destabilization of tracts of simple repetitive DNA in yeast by mutations affecting DNA mismatch repair

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7 January 2021

Dynamic mutations: a new class of mutations causing human disease

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7 January 2021

Questions of expansion

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7 January 2021

Genetic heterogeneity of the c-K-ras locus in colorectal adenomas but not in adenocarcinomas.

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7 January 2021

Loss of constitutional heterozygosity in human cancer.

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Dynamic instability of chromosomes and genomes

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Frameshift mutation: determinants of specificity

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7 January 2021

The clonal evolution of tumor cell populations

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Biological asymmetries and the fidelity of eukaryotic DNA replication

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DNA structure, mutations, and human genetic disease

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7 January 2021

Preferential DNA secondary structure mutagenesis in the lagging strand of replication in E. coli

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7 January 2021

Survey of human and rat microsatellites.

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7 January 2021

Clonality: more than just a tumor-progression model

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7 January 2021

Flat Adenomas in a Colon Cancer-Prone Kindred1

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7 January 2021

Slippery DNA and diseases

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7 January 2021

Fingerprinting genomes using PCR with arbitrary primers

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7 January 2021

[21] Specific synthesis of DNA in vitro via a polymerase-catalyzed chain reaction

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Dinucleotide repeat polymorphisms at the D5S107, D5S108, D5S111, D5S117 and D5S118 loci

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7 January 2021

Human colonic adenocarcinoma cells. I. Establishment and description of a new line

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The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer

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7 January 2021

Mutations of a mutS homolog in hereditary nonpolyposis colorectal cancer

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7 January 2021

Hypermutability and mismatch repair deficiency in RER+ tumor cells

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7 January 2021

Identifiers

DOI

10.1038/NG0394-273

1 reference

19 December 2017

PubMed ID

8012390

1 reference

19 December 2017