Tumour-specific therapeutic adenovirus vectors: repression of transgene expression in healthy cells by endogenous p53. (Q45876483)

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6 November 2019

title

Tumour-specific therapeutic adenovirus vectors: repression of transgene expression in healthy cells by endogenous p53 (English)

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6 November 2019

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4

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6 November 2019

author name string

Lipinski KS

1

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6 November 2019

Djeha AH

2

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6 November 2019

Krausz E

3

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6 November 2019

Searle PF

5

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6 November 2019

Mountain A

6

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6 November 2019

Wrighton CJ

7

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6 November 2019

publication date

1 February 2001

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6 November 2019

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6 November 2019

volume

8

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6 November 2019

issue

4

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6 November 2019

page(s)

274-281

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Adenovirus targeted to heparan-containing receptors increases its gene delivery efficiency to multiple cell types

6 November 2019

cites work

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p53--an acrobat in tumorigenesis

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Targeting gene expression to tumor cells with loss of wild-type p53 function

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Combined adenovirus-mediated nitroreductase gene delivery and CB1954 treatment: a well-tolerated therapy for established solid tumors

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Stabilization of the p53 tumor suppressor is induced by adenovirus 5 E1A and accompanies apoptosis

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p53 represses CAAT enhancer-binding protein (C/EBP)-dependent transcription of the albumin gene. A molecular mechanism involved in viral liver infection with implications for hepatocarcinogenesis.

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Activation of the heat shock transcription factor by hypoxia in mammalian cells

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A transcription activation system for regulated gene expression in transgenic plants

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Inducible gene expression systems for higher eukaryotic cells

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Inhibition of gene expression with ribozymes.

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New helper cells and matched early region 1-deleted adenovirus vectors prevent generation of replication-competent adenoviruses.

21 January 2018

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Rapid detection of octamer binding proteins with 'mini-extracts', prepared from a small number of cells

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Generation of recombinant adenovirus vectors with modified fibers for altering viral tropism.

21 January 2018

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7 January 2021

Increased in vitro and in vivo gene transfer by adenovirus vectors containing chimeric fiber proteins.

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7 January 2021

Targeted adenovirus gene transfer to endothelial and smooth muscle cells by using bispecific antibodies

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7 January 2021

A new cytotoxic, DNA interstrand crosslinking agent, 5-(aziridin-1-yl)-4-hydroxylamino-2-nitrobenzamide, is formed from 5-(aziridin-1-yl)-2,4-dinitrobenzamide (CB 1954) by a nitroreductase enzyme in Walker carcinoma cells

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7 January 2021

Evaluation of the transfer and expression in mice of an enzyme-encoding gene using a human adenovirus vector

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7 January 2021

Expression of Escherichia coli B nitroreductase in established human tumor xenografts in mice results in potent antitumoral and bystander effects upon systemic administration of the prodrug CB1954

1 reference

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7 January 2021

Identifiers

DOI

10.1038/SJ.GT.3301403

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11313801%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

6 November 2019

1021686868

0 references

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