Protein destabilization by electrostatic repulsions in the two-stranded alpha-helical coiled-coil/leucine zipper (Q42844614)

8 November 2017

Protein destabilization by electrostatic repulsions in the two-stranded alpha-helical coiled-coil/leucine zipper (English)

1 reference

8 November 2017

W D Kohn

1

1 reference

PMCID

2143052

8 November 2017

C M Kay

series ordinal

2

1 reference

PMCID

2143052

8 November 2017

R S Hodges

series ordinal

3

1 reference

8 November 2017

1 February 1995

1 reference

8 November 2017

1 reference

8 November 2017

4

1 reference

8 November 2017

237-250

1 reference

8 November 2017

2

1 reference

Some factors in the interpretation of protein denaturation

8 November 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143052

Protein design as a challenge for peptide chemists

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143052

A single-stranded amphipathic alpha-helix in aqueous solution: design, structural characterization, and its application for determining alpha-helical propensities of amino acids

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143052

Interactions of coiled coils in transcription factors: where is the specificity?

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143052

Thermodynamic characterization of the structural stability of the coiled-coil region of the bZIP transcription factor GCN4.

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143052

Disulfide bond contribution to protein stability: positional effects of substitution in the hydrophobic core of the two-stranded alpha-helical coiled-coil

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143052

Packing and hydrophobicity effects on protein folding and stability: effects of beta-branched amino acids, valine and isoleucine, on the formation and stability of two-stranded alpha-helical coiled coils/leucine zippers

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143052

Crystal structure of a synthetic triple-stranded alpha-helical bundle

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143052

A switch between two-, three-, and four-stranded coiled coils in GCN4 leucine zipper mutants

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143052

Probing the roles of residues at the e and g positions of the GCN4 leucine zipper by combinatorial mutagenesis.

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143052

Protein denaturation with guanidine hydrochloride or urea provides a different estimate of stability depending on the contributions of electrostatic interactions

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143052

Urea and guanidine hydrochloride denaturation of ribonuclease, lysozyme, alpha-chymotrypsin, and beta-lactoglobulin.

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143052

Structural basis of protein stability and DNA-protein interaction

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143052

Determination and analysis of urea and guanidine hydrochloride denaturation curves

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143052

Helix stabilization by Glu-...Lys+ salt bridges in short peptides of de novo design

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143052

Conformation of peptide fragments of proteins in aqueous solution: implications for initiation of protein folding

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143052

Treatment of electrostatic effects in macromolecular modeling

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143052

Protein design, a minimalist approach.

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143052

Charge effects on folded and unfolded proteins

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143052

Strength and co-operativity of contributions of surface salt bridges to protein stability

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143052

Estimating the contribution of engineered surface electrostatic interactions to protein stability by using double-mutant cycles

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143052

Dominant forces in protein folding

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143052

X-ray structure of the GCN4 leucine zipper, a two-stranded, parallel coiled coil

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143052

Surface electrostatic interactions contribute little of stability of barnase

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143052

Contributions of engineered surface salt bridges to the stability of T4 lysozyme determined by directed mutagenesis

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143052

Designed coiled-coil proteins: synthesis and spectroscopy of two 78-residue .alpha.-helical dimers

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143052

Contribution of the hydrophobic effect to globular protein stability

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143052

Contributions of the polar, uncharged amino acids to the stability of staphylococcal nuclease: evidence for mutational effects on the free energy of the denatured state.

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143052

The GCN4 basic region leucine zipper binds DNA as a dimer of uninterrupted alpha helices: crystal structure of the protein-DNA complex

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143052

Charge repulsion in the conformational stability of melittin

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143052

The contribution of residue ion pairs to the helical stability of a model peptide

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143052

Electrostatic effects in proteins

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143052

Unzipping the secrets of coiled-coils.

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143052

Peptide 'Velcro': design of a heterodimeric coiled coil.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143052

The energetics of ion-pair and hydrogen-bonding interactions in a helical peptide

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143052

The three states of globular proteins: acid denaturation

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143052

Helix propensities of the amino acids measured in alanine-based peptides without helix-stabilizing side-chain interactions.

16 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.1002%2FPRO.5560040210

Successful prediction of the coiled coil geometry of the GCN4 leucine zipper domain by simulated annealing: Comparison to the X-ray structure

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143052

Tropomyosin coiled-coil interactions: Evidence for an unstaggered structure

1 December 2018

1 reference

12 December 2020

The two-stranded alpha-helical coiled-coil is an ideal model for studying protein stability and subunit interactions

1 reference

12 December 2020

Controlled formation of model homo- and heterodimer coiled coil polypeptides

1 reference

12 December 2020

Genetic and structural analysis of the protein stability problem

1 reference

12 December 2020

Energetic contribution of solvent-exposed ion pairs to alpha-helix structure

1 reference

12 December 2020

Mechanism of specificity in the Fos-Jun oncoprotein heterodimer

1 reference

12 December 2020

Synthetic model proteins: contribution of hydrophobic residues and disulfide bonds to protein stability

1 reference

12 December 2020

COMPARATIVE STUDY OF THE ALPHA-HELICAL MUSCLE PROTEINS. TYROSYL TITRATION AND EFFECT OF PH ON CONFORMATION

1 reference

12 December 2020

Dimerization specificity of the leucine zipper-containing bZIP motif on DNA binding: prediction and rational design

1 reference

12 December 2020

Synthesis of a model protein of defined secondary and quaternary structure. Effect of chain length on the stabilization and formation of two-stranded alpha-helical coiled-coils

1 reference

12 December 2020

Comparison of antiparallel and parallel two-stranded alpha-helical coiled-coils. Design, synthesis, and characterization

1 reference

12 December 2020

Reversed-phase chromatography of synthetic amphipathic α-helical peptides as a model for ligand/receptor interactions Effect of changing hydrophobic environment on the relative hydrophilicity/hydrophobicity of amino acid side-chains

1 reference

12 December 2020

Protein design using model synthetic peptides

1 reference

12 December 2020

Synthetic model for two-stranded alpha-helical coiled-coils. Design, synthesis, and characterization of an 86-residue analog of tropomyosin

1 reference

12 December 2020

Circular dichroism study on the conformational stability of the dimerization domain of transcription factor LFB1

1 reference

12 December 2020

Design, synthesis and structural characterization of model heterodimeric coiled-coil proteins

1 reference

12 December 2020

Reversed-phase liquid chromatography as a useful probe of hydrophobic interactions involved in protein folding and protein stability

1 reference

12 December 2020

Is the hydrophobic effect stabilizing or destabilizing in proteins?

1 reference

12 December 2020

Identifiers

DOI

10.1002/PRO.5560040210

1 reference

8 November 2017

1 reference

8 November 2017

1 reference

PMCID

2143052