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tolvaptan (Q426132)

From Wikidata
selective, competitive vasopressin receptor 2 antagonist used to treat hyponatremia (low blood sodium levels) associated with congestive heart failure, cirrhosis, and the syndrome of inappropriate antidiuretic hormone
  • OPC-41061
  • Samsca®
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Language Label Description Also known as
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No label defined
    English
    tolvaptan
    selective, competitive vasopressin receptor 2 antagonist used to treat hyponatremia (low blood sodium levels) associated with congestive heart failure, cirrhosis, and the syndrome of inappropriate antidiuretic hormone
    • OPC-41061
    • Samsca®

    Statements

    has use
    medication
    0 references
    chemical formula
    C₂₆H₂₅ClN₂O₃
    1 reference
    stated in
    PubChem
    PubChem CID
    216237
    language of work or name
    English
    title
    Tolvaptan (English)
    retrieved
    18 November 2016
    canonical SMILES
    CC1=CC=CC=C1C(=O)NC2=CC(=C(C=C2)C(=O)N3CCCC(C4=C3C=CC(=C4)Cl)O)C
    1 reference
    stated in
    PubChem
    PubChem CID
    216237
    language of work or name
    English
    title
    Tolvaptan (English)
    retrieved
    18 November 2016
    legal status (medicine)
    boxed warning
    1 reference
    reference URL
    https://nctr-crs.fda.gov/fdalabel/ui/spl-summaries/criteria/343802
    title
    FDA-sourced list of all drugs with black box warnings (Use Download Full Results and View Query links. (English)
    mass
    448.155 dalton
    1 reference
    stated in
    PubChem
    PubChem CID
    216237
    language of work or name
    English
    title
    Tolvaptan (English)
    retrieved
    18 November 2016
    Commons category
    Tolvaptan
    0 references

    Identifiers

    HSDB ID
    8196
    1 reference
    stated in
    Hazardous Substances Data Bank
    HSDB ID
    8196
    publication date
    28 October 2019
    title
    Tolvaptan (English)
    retrieved
    10 May 2021
    EC number
    691-537-5
    1 reference
    stated in
    ECHA Substance Infocard database
    ECHA Substance Infocard ID
    100.219.212
    retrieved
    27 December 2018
    title
    N-(4-{[(5S)-7-chloro-5-hydroxy-2,3,4,5-tetrahydro-1H-1-benzazepin-1-yl]carbonyl}-3-methylphenyl)-2-methylbenzamide (English)
    quotation
    CAS no.: 150683-30-0 (English)
    ECHA Substance Infocard ID
    100.219.212
    1 reference
    stated in
    ECHA Substance Infocard database
    ECHA Substance Infocard ID
    100.219.212
    retrieved
    27 December 2018
    title
    N-(4-{[(5S)-7-chloro-5-hydroxy-2,3,4,5-tetrahydro-1H-1-benzazepin-1-yl]carbonyl}-3-methylphenyl)-2-methylbenzamide (English)
    quotation
    CAS no.: 150683-30-0 (English)
    DeCS ID
    57705
    0 references
     
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