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Colony stimulating factor 2 (Q423660)

From Wikidata

mammalian protein found in Homo sapiens

granulocyte macrophage-colony stimulating factor
colony stimulating factor 2 (granulocyte-macrophage)
Colony-stimulating factor
granulocyte-macrophage colony-stimulating factor
CSF

Language	Label	Description	Also known as
default for all languages	No label defined
English	Colony stimulating factor 2	mammalian protein found in Homo sapiens	granulocyte macrophage-colony stimulating factor colony stimulating factor 2 (granulocyte-macrophage) Colony-stimulating factor granulocyte-macrophage colony-stimulating factor CSF

Statements

1 reference

13 November 2019

UniProt protein ID

granulocyte-macrophage colony-stimulating factor

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P04141

four-helical cytokine-like, core

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P04141

GMCSF Crystal Structure.rsh.png
900 × 750; 236 KB

Structure cristalline du GM-CSF telle que publiée dans la Protein Data Bank (French)

0 references

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

protein binding

determination method or standard

3 references

8 April 2019

A proteome-scale map of the human interactome network

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04141

determination method or standard

8 April 2019

The structure of the GM-CSF receptor complex reveals a distinct mode of cytokine receptor activation

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04141

determination method or standard

8 April 2019

Widespread macromolecular interaction perturbations in human genetic disorders

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04141

determination method or standard

protein tyrosine kinase activity

determination method or standard

1 reference

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04141&geneProductId=UniProtKB:P04141

determination method or standard

cytokine activity

determination method or standard

3 references

27 March 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04141&geneProductId=UniProtKB:P04141

determination method or standard

27 March 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04141&geneProductId=UniProtKB:P04141

determination method or standard

27 March 2018

Isolation of cDNA for a human granulocyte-macrophage colony-stimulating factor by functional expression in mammalian cells

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04141&geneProductId=UniProtKB:P04141

determination method or standard

cytokine activity

determination method or standard

4 references

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04141

determination method or standard

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04141

determination method or standard

8 April 2019

Isolation of cDNA for a human granulocyte-macrophage colony-stimulating factor by functional expression in mammalian cells

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04141

determination method or standard

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04141

determination method or standard

extracellular region

determination method or standard

intracellular membrane-bounded organelle

determination method or standard

1 reference

8 April 2019

Human Protein Atlas

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04141

determination method or standard

extracellular space

determination method or standard

3 references

27 March 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04141&geneProductId=UniProtKB:P04141

determination method or standard

27 March 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04141&geneProductId=UniProtKB:P04141

determination method or standard

27 March 2018

Isolation of cDNA for a human granulocyte-macrophage colony-stimulating factor by functional expression in mammalian cells

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04141&geneProductId=UniProtKB:P04141

determination method or standard

extracellular space

determination method or standard

4 references

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04141

determination method or standard

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04141

determination method or standard

8 April 2019

Isolation of cDNA for a human granulocyte-macrophage colony-stimulating factor by functional expression in mammalian cells

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04141

determination method or standard

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04141

determination method or standard

biological process

negative regulation of cytolysis

determination method or standard

1 reference

8 April 2019

The CXC-chemokine platelet factor 4 promotes monocyte survival and induces monocyte differentiation into macrophages

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04141

determination method or standard

positive regulation of macrophage derived foam cell differentiation

determination method or standard

1 reference

8 April 2019

Interleukin-1beta and tumour necrosis factor-alpha impede neutral lipid turnover in macrophage-derived foam cells

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04141

determination method or standard

regulation of cell population proliferation

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04141

determination method or standard

determination method or standard

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04141

determination method or standard

positive regulation of podosome assembly

determination method or standard

1 reference

8 April 2019

Eosinophils adhere to vascular cell adhesion molecule-1 via podosomes

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04141

determination method or standard

negative regulation of extrinsic apoptotic signaling pathway in absence of ligand

determination method or standard

1 reference

8 April 2019

The CXC-chemokine platelet factor 4 promotes monocyte survival and induces monocyte differentiation into macrophages

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04141

determination method or standard

positive regulation of interleukin-23 production

determination method or standard

1 reference

8 April 2019

Salmonella induced IL-23 and IL-1beta allow for IL-12 production by monocytes and Mphi1 through induction of IFN-gamma in CD56 NK/NK-like T cells

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04141

determination method or standard

positive regulation of gene expression

determination method or standard

1 reference

8 April 2019

The CXC-chemokine platelet factor 4 promotes monocyte survival and induces monocyte differentiation into macrophages

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04141

determination method or standard

embryonic placenta development

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04141

determination method or standard

epithelial fluid transport

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04141

determination method or standard

regulation of gene expression

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04141

determination method or standard

macrophage activation

determination method or standard

1 reference

1 January 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04141

determination method or standard

cellular response to lipopolysaccharide

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04141

determination method or standard

immune response

determination method or standard

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04141

determination method or standard

monocyte differentiation

determination method or standard

1 reference

1 January 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04141

determination method or standard

response to fluid shear stress

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04141

determination method or standard

response to silicon dioxide

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04141

determination method or standard

neutrophil differentiation

determination method or standard

1 reference

1 January 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04141

determination method or standard

peptidyl-tyrosine phosphorylation

determination method or standard

1 reference

10 September 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04141&geneProductId=UniProtKB:P04141

determination method or standard

regulation of circadian sleep/wake cycle, sleep

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04141

determination method or standard

histamine secretion

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04141

determination method or standard

positive regulation of tyrosine phosphorylation of STAT protein

determination method or standard

1 reference

8 April 2019

Insulin-like Growth Factor-I Augments Erythropoietin-induced Proliferation through Enhanced Tyrosine Phosphorylation of STAT5

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04141

determination method or standard

cellular response to granulocyte macrophage colony-stimulating factor stimulus

determination method or standard

1 reference

8 April 2019

CD4 Ligation on Human Blood Monocytes Triggers Macrophage Differentiation and Enhances HIV Infection

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04141

determination method or standard

regulation of myeloid cell differentiation

determination method or standard

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04141

determination method or standard

regulation of signaling receptor activity

determination method or standard

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04141

determination method or standard

negative regulation of transcription, DNA-templated

determination method or standard

1 reference

8 April 2019

B7-H4 expression identifies a novel suppressive macrophage population in human ovarian carcinoma

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04141

determination method or standard

cytokine-mediated signaling pathway

determination method or standard

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04141

determination method or standard

macrophage differentiation

determination method or standard

1 reference

8 April 2019

CD4 Ligation on Human Blood Monocytes Triggers Macrophage Differentiation and Enhances HIV Infection

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04141

determination method or standard

Gene Atlas image

PBB GE CSF2 210229 s at fs.png
732 × 530; 11 KB

0 references

http://purl.uniprot.org/uniprot/P04141

1 reference

Identifiers.org

0 references

Identifiers

CAS Registry Number

1 reference

19 October 2015

RefSeq protein ID

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000296871

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000296871

1 reference

Freebase Data Dumps

publication date

28 October 2013

Microsoft Academic ID

0 references

1 reference

26 January 2022

https://docs.openalex.org/download-snapshot/snapshot-data-format

PDB structure ID

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

Sitelinks

Wikipedia(19 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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