Novel PEGylated basal insulin LY2605541 has a preferential hepatic effect on glucose metabolism (Q42031194)

15 October 2017

Novel PEGylated basal insulin LY2605541 has a preferential hepatic effect on glucose metabolism (English)

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15 October 2017

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7

Alan D Cherrington

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15 October 2017

Mary E. Courtney Moore

1

object named as

Mary Courtney Moore

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15 October 2017

2

Marta S Smith

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15 October 2017

Vikram P Sinha

3

1 reference

15 October 2017

John M Beals

4

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15 October 2017

M Dodson Michael

5

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15 October 2017

Scott J Jacober

6

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15 October 2017

language of work or name

English

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publication date

2 October 2013

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15 October 2017

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15 October 2017

63

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15 October 2017

2

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15 October 2017

494-504

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Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported

15 October 2017

start time

30 August 2021

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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describes a project that uses

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC5361402/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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Better glycemic control and weight loss with the novel long-acting basal insulin LY2605541 compared with insulin glargine in type 1 diabetes: a randomized, crossover study

5 June 2018

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A randomized, controlled study of once-daily LY2605541, a novel long-acting basal insulin, versus insulin glargine in basal insulin-treated patients with type 2 diabetes

5 June 2018

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Brain insulin action augments hepatic glycogen synthesis without suppressing glucose production or gluconeogenesis in dogs.

5 June 2018

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A high-fat, high-fructose diet accelerates nutrient absorption and impairs net hepatic glucose uptake in response to a mixed meal in partially pancreatectomized dogs

5 June 2018

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Hypoglycemia rates with basal insulin analogs

5 June 2018

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Optimizing the replacement of basal insulin in type 1 diabetes mellitus: no longer an elusive goal in the post-NPH era.

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Comparison of insulins detemir and glargine: effects on glucose disposal, hepatic glucose release and the central nervous system

5 June 2018

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Insulin degludec in type 1 diabetes: a randomized controlled trial of a new-generation ultra-long-acting insulin compared with insulin glargine.

5 June 2018

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Insulin detemir is not transported across the blood–brain barrier

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Mechanisms of insulin resistance after insulin-induced hypoglycemia in humans: the role of lipolysis

5 June 2018

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Molecular characterization of insulin-mediated suppression of hepatic glucose production in vivo

5 June 2018

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Effects of insulin on the metabolic control of hepatic gluconeogenesis in vivo.

5 June 2018

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5 June 2018

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A physiological increase in the hepatic glycogen level does not affect the response of net hepatic glucose uptake to insulin

5 June 2018

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5 June 2018

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5 June 2018

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Effects of vagal blockade on the counterregulatory response to insulin-induced hypoglycemia in the dog.

5 June 2018

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In the absence of counterregulatory hormones, the increase in hepatic glucose production during insulin-induced hypoglycemia in the dog is initiated in the liver rather than the brain

5 June 2018

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Causal linkage between insulin suppression of lipolysis and suppression of liver glucose output in dogs

5 June 2018

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Demonstration of a critical role for free fatty acids in mediating counterregulatory stimulation of gluconeogenesis and suppression of glucose utilization in humans

5 June 2018

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Growth hormone and diabetes mellitus. A review of sixty-three years of medical research and a glimpse into the future?

5 June 2018

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Role of hepatic STAT3 in brain-insulin action on hepatic glucose production

5 June 2018

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17 August 2018

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A circulatory model for calculating non-steady-state glucose fluxes. Validation and comparison with compartmental models

17 August 2018

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Direct and indirect effects of insulin on glucose uptake and storage by the liver

17 August 2018

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A negative arterial-portal venous glucose gradient decreases skeletal muscle glucose uptake.

17 August 2018

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Basal hepatic glucose production is regulated by the portal vein insulin concentration.

17 August 2018

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Serum proteins bypass the blood-brain fluid barriers for extracellular entry to the central nervous system

17 August 2018

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Blood to brain and brain to blood passage of native horseradish peroxidase, wheat germ agglutinin, and albumin: pharmacokinetic and morphological assessments

17 August 2018

1 reference

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Ultra-long-acting insulin degludec has a flat and stable glucose-lowering effect in type 2 diabetes

17 August 2018

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12 December 2020

The role of fatty acids in mediating the effects of peripheral insulin on hepatic glucose production in the conscious dog

1 reference

12 December 2020

Novel hepatoselective insulin analog: studies with a covalently linked thyroxyl-insulin complex in humans

1 reference

12 December 2020

A comparison of the effects of selective increases in peripheral or portal insulin on hepatic glucose production in the conscious dog

1 reference

12 December 2020

Alcohol Intake Impairs Glucose Counterregulation During Acute Insulin-Induced Hypoglycemia in IDDM Patients: Evidence for a Critical Role of Free Fatty Acids

1 reference

12 December 2020

Albumin binding and time action of acylated insulins in various species

1 reference

12 December 2020

Impact of chronic stress hormone infusion on hepatic carbohydrate metabolism in the conscious dog

1 reference

12 December 2020

First-pass hepatic extraction and metabolic effects of insulin and insulin analogues

1 reference

12 December 2020

Neural and pancreatic influences on net hepatic glucose uptake and glycogen synthesis

1 reference

12 December 2020

Intraperitoneal insulin affects insulin-like growth factor binding protein-1 in a well-controlled type I diabetic patient

1 reference

12 December 2020

A negative arterial-portal venous glucose gradient increases net hepatic glucose uptake in euglycemic dogs

1 reference

12 December 2020

Metabolic regulation in peripheral tissues and transition to increased gluconeogenic mode during prolonged exercise

1 reference

12 December 2020

Effect of hepatic denervation on the counterregulatory response to insulin-induced hypoglycemia in the dog

1 reference

12 December 2020

Identifiers

DOI

10.2337/DB13-0826

1 reference

15 October 2017

1 reference

15 October 2017

PubMed publication ID

24089512

1 reference