topotecan (Q419953)

has use

medication

0 references

chemical structure

Topotecan Structural Formula V.1.svg
600 × 486; 34 KB

1 reference

https://ru.wikipedia.org/?oldid=99430861

Russian Wikipedia

Wikimedia import URL

mass

421.164 dalton

1 reference

topotecan (English)

18 November 2016

C₂₃H₂₃N₃O₅

1 reference

topotecan (English)

18 November 2016

CCC1(C2=C(COC1=O)C(=O)N3CC4=C(C3=C2)N=C5C=CC(=C(C5=C4)CN(C)C)O)O

1 reference

topotecan (English)

18 November 2016

CC[C@@]1(C2=C(COC1=O)C(=O)N3CC4=C(C3=C2)N=C5C=CC(=C(C5=C4)CN(C)C)O)O

1 reference

topotecan (English)

18 November 2016

1 reference

EMEA/H/C/000124

http://www.ema.europa.eu/ema/index.jsp?curl=pages/medicines/human/medicines/000124/human_med_000774.jsp

22 March 2017

1 reference

14 February 2018

1 reference

EMEA/H/C/002282

http://www.ema.europa.eu/ema/index.jsp?curl=pages/medicines/human/medicines/002282/human_med_001407.jsp

22 March 2017

Topotecan Actavis

1 reference

EMEA/H/C/001031

http://www.ema.europa.eu/ema/index.jsp?curl=pages/medicines/human/medicines/001031/human_med_001096.jsp

22 March 2017

Topotecan Hospira

1 reference

EMEA/H/C/001192

http://www.ema.europa.eu/ema/index.jsp?curl=pages/medicines/human/medicines/001192/human_med_001348.jsp

22 March 2017

Topotecan Teva

1 reference

EMEA/H/C/001071

http://www.ema.europa.eu/ema/index.jsp?curl=pages/medicines/human/medicines/001071/human_med_001097.jsp

World Health Organisation international non-proprietary name

22 March 2017

topotecan (English)

1 reference

topotecan (English)

medical condition treated

19 October 2016

lung oat cell carcinoma

1 reference

13 December 2016

1 reference

13 December 2016

1 reference

non-small-cell lung carcinoma

13 December 2016

1 reference

Drug Indications Extracted from FAERS

13 December 2016

1 reference

neuroblastoma, susceptibility to

2 October 2018

1 reference

Drug Indications Extracted from FAERS

lung small cell carcinoma

2 October 2018

start time

27 May 1996

approved by

Food and Drug Administration

1 reference

Inxight: Drugs Database

2 November 2018

https://drugs.ncats.io/drug/7M7YKX2N15

http://www.accessdata.fda.gov/drugsatfda_docs/label/2015/020671s021lbl.pdf

ovarian carcinoma

start time

27 May 1996

approved by

Food and Drug Administration

1 reference

Inxight: Drugs Database

2 November 2018

https://drugs.ncats.io/drug/7M7YKX2N15

http://www.accessdata.fda.gov/drugsatfda_docs/label/2015/020671s021lbl.pdf

legal status (medicine)

boxed warning

1 reference

https://nctr-crs.fda.gov/fdalabel/ui/spl-summaries/criteria/343802

Australian pregnancy category D

FDA-sourced list of all drugs with black box warnings (Use Download Full Results and View Query links. (English)

pregnancy category

1 reference

English Wikipedia

US pregnancy category D

1 reference

https://www.pfizer.com/products/product-list

1 reference

subject has role

topoisomerase inhibitor

1 reference

5 March 2018

topoisomerase I inhibitor

1 reference

InChI=1S/C23H23N3O5/c1-4-23(30)16-8-18-20-12(9-26(18)21(28)15(16)11-31-22(23)29)7-13-14(10-25(2)3)19(27)6-5-17(13)24-20/h5-8,27,30H,4,9-11H2,1-3H3/t23-/m0/s1

Medical Subject Headings

15 March 2018

0 references

0 references

Topotecan

0 references

Identifiers

InChI

1 reference

topotecan (English)

18 November 2016

2 references

topotecan (English)

18 November 2016

ChEBI release 2020-09-01

CAS Registry Number

123948-87-8

2 references

topotecan (English)

18 November 2016

https://commonchemistry.cas.org/detail?cas_rn=123948-87-8

8 April 2021

1 reference

Topotecan (English)

18 November 2016

2 references

topotecan (English)

18 November 2016

Reaxys registry number

4279441

1 reference

topotecan (English)

19 October 2016

mapping relation type

2 references

TOPOTECAN (English)

18 November 2016

International Chemical Identifier

InChI

InChI=1S/C23H23N3O5/c1-4-23(30)16-8-18-20-12(9-26(18)21(28)15(16)11-31-22(23)29)7-13-14(10-25(2)3)19(27)6-5-17(13)24-20/h5-8,27,30H,4,9-11H2,1-3H3/t23-/m0/s1

1 reference

TOPOTECAN (English)

18 November 2016

2 references

Hazardous Substances Data Bank

1 reference

1 reference

28 October 2019

Topotecan (English)

10 May 2021

2 references

Mapping file of InChIStrings, InChIKeys and DTXSIDs for the EPA CompTox Dashboard

DSSTOX compound identifier

0 references

0 references

0 references

ECHA Substance Infocard ID

100.213.372

1 reference

ECHA Substance Infocard database

ECHA Substance Infocard ID

100.213.372

27 December 2018

4-Ethyl-4,9-dihydroxy-10-[(dimethylamino)methyl]-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione; (English)

quotation

CAS no.: 123948-87-8 (English)

1 reference

Guide to Pharmacology Ligand ID

Topotecan (English)

publication date

17 November 2015

7101

1 reference

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

7101

topotecan (English)

18 November 2016

Topotecan

0 references

0 references

0 references

1 reference

topotecan (English)

18 November 2016

1 reference

Human Metabolome Database ID

HMDB0015164

2 references

based on heuristic

KNApSAcK ID

C00052420

2 references

based on heuristic

2 references

topotecan (English)

18 November 2016

MedlinePlus drug identifier

a610007

route of administration

oral administration

0 references

a697006

route of administration

intravenous injection

0 references

NDF-RT ID

N0000022037

1 reference

topotecan (English)

18 November 2016

0 references

1 reference

1 reference

https://docs.openalex.org/download-snapshot/snapshot-data-format

topotecan (English)

19 October 2016

0 references

0 references

1 reference

28 October 2013

Microsoft Academic ID

0 references

0 references

1 reference

26 January 2022

1 reference

1RR8 (English)

19 October 2016

1 reference

1K4T (English)

19 October 2016

1 reference

1RRJ (English)

19 October 2016

1 reference

1 reference