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Identification of conjugation specificity determinants unmasks vestigial preference for ubiquitin within the NEDD8 E2. (Q41792392)

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scientific article published on 10 February 2008

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English	Identification of conjugation specificity determinants unmasks vestigial preference for ubiquitin within the NEDD8 E2.	scientific article published on 10 February 2008

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18264111%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

Identification of conjugation specificity determinants unmasks vestigial preference for ubiquitin within the NEDD8 E2 (English)

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2 January 2020

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2 January 2020

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Min Zhuang

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2 January 2020

Olivier Ayrault

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2 January 2020

Brenda A Schulman

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2 January 2020

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10 February 2008

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2 January 2020

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Nature Structural & Molecular Biology

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2 January 2020

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2 January 2020

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2 January 2020

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2 January 2020

Polyubiquitin chains: polymeric protein signals

1 reference

https://api.crossref.org/works/10.1038%2FNSMB.1387

31 March 2020

Ubiquitin-binding domains

1 reference

https://api.crossref.org/works/10.1038%2FNSMB.1387

31 March 2020

Ubiquitin-binding domains

1 reference

https://api.crossref.org/works/10.1038%2FNSMB.1387

31 March 2020

Structural complexity in ubiquitin recognition.

1 reference

https://api.crossref.org/works/10.1038%2FNSMB.1387

31 March 2020

Modification of proteins by ubiquitin and ubiquitin-like proteins

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https://api.crossref.org/works/10.1038%2FNSMB.1387

31 March 2020

Structural mechanisms underlying posttranslational modification by ubiquitin-like proteins

1 reference

https://api.crossref.org/works/10.1038%2FNSMB.1387

31 March 2020

A superfamily of protein tags: ubiquitin, SUMO and related modifiers

1 reference

https://api.crossref.org/works/10.1038%2FNSMB.1387

31 March 2020

Nedd8 on cullin: building an expressway to protein destruction.

1 reference

https://api.crossref.org/works/10.1038%2FNSMB.1387

31 March 2020

Covalent modifier NEDD8 is essential for SCF ubiquitin-ligase in fission yeast

1 reference

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31 March 2020

The NEDD8 system is essential for cell cycle progression and morphogenetic pathway in mice

1 reference

https://api.crossref.org/works/10.1038%2FNSMB.1387

31 March 2020

Ubiquitin: structures, functions, mechanisms

1 reference

https://api.crossref.org/works/10.1038%2FNSMB.1387

31 March 2020

Conservation in the Mechanism of Nedd8 Activation by the Human AppBp1-Uba3 Heterodimer

1 reference

https://api.crossref.org/works/10.1038%2FNSMB.1387

31 March 2020

Structural basis for recruitment of Ubc12 by an E2 binding domain in NEDD8's E1

1 reference

https://api.crossref.org/works/10.1038%2FNSMB.1387

31 March 2020

E2 conjugating enzymes must disengage from their E1 enzymes before E3-dependent ubiquitin and ubiquitin-like transfer

1 reference

https://api.crossref.org/works/10.1038%2FNSMB.1387

31 March 2020

Small but versatile: the extraordinary functional and structural diversity of the beta-grasp fold

1 reference

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31 March 2020

Dual E1 activation systems for ubiquitin differentially regulate E2 enzyme charging

1 reference

https://api.crossref.org/works/10.1038%2FNSMB.1387

31 March 2020

UBE1L2, a novel E1 enzyme specific for ubiquitin

1 reference

https://api.crossref.org/works/10.1038%2FNSMB.1387

31 March 2020

E1-L2 activates both ubiquitin and FAT10

1 reference

https://api.crossref.org/works/10.1038%2FNSMB.1387

31 March 2020

A novel protein modification pathway related to the ubiquitin system

1 reference

https://api.crossref.org/works/10.1038%2FNSMB.1387

31 March 2020

A new NEDD8-ligating system for cullin-4A

1 reference

https://api.crossref.org/works/10.1038%2FNSMB.1387

31 March 2020

Identification of the activating and conjugating enzymes of the NEDD8 conjugation pathway

1 reference

https://api.crossref.org/works/10.1038%2FNSMB.1387

31 March 2020

Commensal bacteria modulate cullin-dependent signaling via generation of reactive oxygen species

1 reference

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31 March 2020

Basis for a ubiquitin-like protein thioester switch toggling E1–E2 affinity

1 reference

https://api.crossref.org/works/10.1038%2FNSMB.1387

31 March 2020

A unique E1-E2 interaction required for optimal conjugation of the ubiquitin-like protein NEDD8

1 reference

https://api.crossref.org/works/10.1038%2FNSMB.1387

31 March 2020

Automated design of specificity in molecular recognition

1 reference

https://api.crossref.org/works/10.1038%2FNSMB.1387

31 March 2020

Specificity versus stability in computational protein design

1 reference

https://api.crossref.org/works/10.1038%2FNSMB.1387

31 March 2020

High-resolution epitope mapping of hGH-receptor interactions by alanine-scanning mutagenesis

1 reference

https://api.crossref.org/works/10.1038%2FNSMB.1387

31 March 2020

Autonomous regulation of the anaphase-promoting complex couples mitosis to S-phase entry.

1 reference

https://api.crossref.org/works/10.1038%2FNSMB.1387

31 March 2020

Structure of a c-Cbl-UbcH7 complex: RING domain function in ubiquitin-protein ligases

1 reference

https://api.crossref.org/works/10.1038%2FNSMB.1387

31 March 2020

Chaperoned ubiquitylation--crystal structures of the CHIP U box E3 ubiquitin ligase and a CHIP-Ubc13-Uev1a complex

1 reference

https://api.crossref.org/works/10.1038%2FNSMB.1387

31 March 2020

E2-BRCA1 RING interactions dictate synthesis of mono- or specific polyubiquitin chain linkages

1 reference

https://api.crossref.org/works/10.1038%2FNSMB.1387

31 March 2020

Insights into the ubiquitin transfer cascade from the structure of the activating enzyme for NEDD8

1 reference

https://api.crossref.org/works/10.1038%2FNSMB.1387

31 March 2020

Structures of the SUMO E1 provide mechanistic insights into SUMO activation and E2 recruitment to E1

1 reference

https://api.crossref.org/works/10.1038%2FNSMB.1387

31 March 2020

Crystal structure of a fragment of mouse ubiquitin-activating enzyme

1 reference

https://api.crossref.org/works/10.1038%2FNSMB.1387

31 March 2020

The Intrinsic Affinity between E2 and the Cys Domain of E1 in Ubiquitin-like Modifications

1 reference

https://api.crossref.org/works/10.1038%2FNSMB.1387

31 March 2020

Subcellular localization and ubiquitin-conjugating enzyme (E2) interactions of mammalian HECT family ubiquitin protein ligases

1 reference

https://api.crossref.org/works/10.1038%2FNSMB.1387

31 March 2020

Human ubiquitin-protein ligase Nedd4: expression, subcellular localization and selective interaction with ubiquitin-conjugating enzymes

1 reference

https://api.crossref.org/works/10.1038%2FNSMB.1387

31 March 2020

Insights into E3 ligase activity revealed by a SUMO-RanGAP1-Ubc9-Nup358 complex

1 reference

https://api.crossref.org/works/10.1038%2FNSMB.1387

31 March 2020

Cdc53/cullin and the essential Hrt1 RING-H2 subunit of SCF define a ubiquitin ligase module that activates the E2 enzyme Cdc34

1 reference

https://api.crossref.org/works/10.1038%2FNSMB.1387

31 March 2020

Rbx1, a component of the VHL tumor suppressor complex and SCF ubiquitin ligase

1 reference

https://api.crossref.org/works/10.1038%2FNSMB.1387

31 March 2020

ROC1, a homolog of APC11, represents a family of cullin partners with an associated ubiquitin ligase activity

1 reference

https://api.crossref.org/works/10.1038%2FNSMB.1387

31 March 2020

Nedd8-modification of Cul1 is promoted by Roc1 as a Nedd8-E3 ligase and regulates its stability

1 reference

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31 March 2020

Mdm2-mediated NEDD8 conjugation of p53 inhibits its transcriptional activity

1 reference

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31 March 2020

Sequential E2s drive polyubiquitin chain assembly on APC targets

1 reference

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31 March 2020

Quantitative analysis of in vitro ubiquitinated cyclin B1 reveals complex chain topology

1 reference

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31 March 2020

Optimization of specificity in a cellular protein interaction network by negative selection

1 reference

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31 March 2020

A quantitative protein interaction network for the ErbB receptors using protein microarrays

1 reference

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31 March 2020

Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF ubiquitin ligase complex

1 reference

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31 March 2020

Identifiers

10.1038/NSMB.1387

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18264111%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18264111%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

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