Prostaglandin-endoperoxide synthase 2 (Q415364)

From Wikidata

Jump to navigation Jump to search

human enzyme involved in inflammation

• PGH synthase 2
• PTGS2
• Cyclooxygenase-2
• PGHS-2
• prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
• PHS II
• cyclooxygenase 2b
• prostaglandin G/H synthase 2
• prostaglandin H2 synthase 2
• cyclooxygenase 2
• COX-2

edit

Language	Label	Description	Also known as
English	Prostaglandin-endoperoxide synthase 2	human enzyme involved in inflammation	PGH synthase 2 PTGS2 Cyclooxygenase-2 PGHS-2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) PHS II cyclooxygenase 2b prostaglandin G/H synthase 2 prostaglandin H2 synthase 2 cyclooxygenase 2 COX-2

Statements

instance of

protein

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

P35354

part of

Prostaglandin G/H synthase 2

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P35354

Haem peroxidase domain superfamily, animal type

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P35354

Haem peroxidase superfamily

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P35354

EGF-like domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

image

6COX.png
1,600 × 1,196; 1.48 MB

0 references

found in taxon

Homo sapiens

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

P35354

encoded by

PTGS2

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

P35354

molecular function

arachidonate 15-lipoxygenase activity

determination method

TAS

1 reference

retrieved

7 November 2018

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P35354&geneProductId=UniProtKB:P35354

determination method

TAS

metal ion binding

determination method

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P35354

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35354

determination method

IEA

heme binding

determination method

ISS

IEA

3 references

retrieved

9 May 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P35354

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35354

determination method

ISS

retrieved

9 May 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35354

determination method

IEA

retrieved

9 May 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35354

determination method

IEA

enzyme binding

determination method

IPI

1 reference

retrieved

9 May 2019

stated in

Inducible nitric oxide synthase binds, S-nitrosylates, and activates cyclooxygenase-2

GOA

curator

UniProt

UniProt protein ID

P35354

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35354

determination method

IPI

oxidoreductase activity

determination method

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P35354

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35354

determination method

IEA

protein homodimerization activity

determination method

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35354

determination method

IEA

dioxygenase activity

determination method

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P35354

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35354

determination method

IEA

protein binding

determination method

IPI

1 reference

retrieved

9 May 2019

stated in

Caveolin-1 interacts with Derlin-1 and promotes ubiquitination and degradation of cyclooxygenase-2 via collaboration with p97 complex

GOA

curator

Parkinsons Disease Gene Ontology Initiative

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35354

determination method

IPI

peroxidase activity

determination method

IEA

NAS

TAS

4 references

retrieved

7 November 2018

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P35354&geneProductId=UniProtKB:P35354

determination method

TAS

retrieved

7 November 2018

stated in

Expression and localization of cyclooxygenase‐1 and ‐2 in human sporadic amyotrophic lateral sclerosis

GOA

curator

UniProt

UniProt protein ID

P35354

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P35354&geneProductId=UniProtKB:P35354

determination method

NAS

retrieved

7 November 2018

stated in

GOA

curator

UniProt

UniProt protein ID

P35354

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P35354&geneProductId=UniProtKB:P35354

determination method

IEA

retrieved

7 November 2018

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P35354&geneProductId=UniProtKB:P35354

determination method

IEA

prostaglandin-endoperoxide synthase activity

determination method

IEA

IDA

TAS

6 references

retrieved

7 November 2018

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P35354&geneProductId=UniProtKB:P35354

determination method

TAS

retrieved

7 November 2018

stated in

GOA

curator

UniProt

UniProt protein ID

P35354

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P35354&geneProductId=UniProtKB:P35354

determination method

IEA

retrieved

7 November 2018

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P35354&geneProductId=UniProtKB:P35354

determination method

IEA

retrieved

7 November 2018

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P35354&geneProductId=UniProtKB:P35354

determination method

IEA

retrieved

7 November 2018

stated in

Inducible nitric oxide synthase binds, S-nitrosylates, and activates cyclooxygenase-2

GOA

curator

UniProt

UniProt protein ID

P35354

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P35354&geneProductId=UniProtKB:P35354

determination method

IDA

retrieved

7 November 2018

stated in

Human cyclooxygenase-2 cDNA

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P35354&geneProductId=UniProtKB:P35354

determination method

IDA

oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen

determination method

IEA

TAS

2 references

retrieved

7 November 2018

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P35354&geneProductId=UniProtKB:P35354

determination method

TAS

retrieved

7 November 2018

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P35354&geneProductId=UniProtKB:P35354

determination method

IEA

peroxidase activity

determination method

IEA

NAS

3 references

retrieved

9 May 2019

stated in

Expression and localization of cyclooxygenase‐1 and ‐2 in human sporadic amyotrophic lateral sclerosis

GOA

curator

UniProt

UniProt protein ID

P35354

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35354

determination method

NAS

retrieved

9 May 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P35354

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35354

determination method

IEA

retrieved

9 May 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35354

determination method

IEA

prostaglandin-endoperoxide synthase activity

determination method

IDA

IEA

5 references

retrieved

9 May 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P35354

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35354

determination method

IEA

retrieved

9 May 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35354

determination method

IEA

retrieved

9 May 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35354

determination method

IEA

retrieved

9 May 2019

stated in

Inducible nitric oxide synthase binds, S-nitrosylates, and activates cyclooxygenase-2

GOA

curator

UniProt

UniProt protein ID

P35354

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35354

determination method

IDA

retrieved

9 May 2019

stated in

Human cyclooxygenase-2 cDNA

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35354

determination method

IDA

oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen

determination method

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35354

determination method

IEA

transferase activity

determination method

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P35354

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35354

determination method

IEA

cell component

cytoplasm

determination method

IDA

ISS

IEA

3 references

retrieved

9 May 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P35354

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35354

determination method

ISS

retrieved

9 May 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35354

determination method

IEA

retrieved

9 May 2019

stated in

Expression and localization of cyclooxygenase‐1 and ‐2 in human sporadic amyotrophic lateral sclerosis

GOA

curator

UniProt

UniProt protein ID

P35354

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35354

determination method

IDA

endoplasmic reticulum lumen

determination method

TAS

1 reference

retrieved

9 May 2019

stated in

Caveolin-1 interacts with Derlin-1 and promotes ubiquitination and degradation of cyclooxygenase-2 via collaboration with p97 complex

GOA

curator

Parkinsons Disease Gene Ontology Initiative

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35354

determination method

TAS

membrane

determination method

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P35354

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35354

determination method

IEA

caveola

determination method

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35354

determination method

IEA

neuron projection

determination method

IDA

IEA

2 references

retrieved

9 May 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35354

determination method

IEA

retrieved

9 May 2019

stated in

Cellular localization of cyclooxygenase-1 and cyclooxygenase-2 in the normal mouse, rat, and human retina

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35354

determination method

IDA

organelle membrane

determination method

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P35354

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35354

determination method

IEA

endoplasmic reticulum

determination method

IDA

IEA

3 references

retrieved

9 May 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P35354

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35354

determination method

IEA

retrieved

9 May 2019

stated in

Caveolin-1 interacts with Derlin-1 and promotes ubiquitination and degradation of cyclooxygenase-2 via collaboration with p97 complex

GOA

curator

Parkinsons Disease Gene Ontology Initiative

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35354

determination method

IDA

retrieved

9 May 2019

stated in

GOA

curator

Human Protein Atlas

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35354

determination method

IDA

intracellular membrane-bounded organelle

determination method

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P35354

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35354

determination method

IEA

endoplasmic reticulum membrane

determination method

TAS

IEA

2 references

retrieved

9 May 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35354

determination method

TAS

retrieved

9 May 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P35354

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35354

determination method

IEA

protein-containing complex

determination method

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35354

determination method

IEA

biological process

response to fructose

determination method

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35354

determination method

IEA

learning

determination method

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35354

determination method

IEA

response to organic substance

determination method

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35354

determination method

IEA

lipoxygenase pathway

determination method

TAS

1 reference

retrieved

9 May 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35354

determination method

TAS

cellular response to mechanical stimulus

determination method

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35354

determination method

IEA

response to manganese ion

determination method

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35354

determination method

IEA

angiogenesis

determination method

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35354

determination method

IEA

cellular response to hypoxia

determination method

IEP

1 reference

retrieved

9 May 2019

stated in

Hypoxia upregulates PGI-synthase and increases PGI₂ release in human vascular cells exposed to inflammatory stimuli

GOA

curator

UniProt

UniProt protein ID

P35354

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35354

determination method

IEP

embryo implantation

determination method

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35354

determination method

IEA

negative regulation of cell population proliferation

determination method

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35354

determination method

IEA

response to cytokine

determination method

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35354

determination method

IEA

negative regulation of smooth muscle contraction

determination method

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35354

determination method

IEA

memory

determination method

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35354

determination method

IEA

response to oxidative stress

determination method

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35354

determination method

IEA

maintenance of blood-brain barrier

determination method

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35354

determination method

IEA

response to lithium ion

determination method

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35354

determination method

IEA

response to tumor necrosis factor

determination method

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35354

determination method

IEA

fatty acid biosynthetic process

determination method

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P35354

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35354

determination method

IEA

positive regulation of synaptic transmission, glutamatergic

determination method

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35354

determination method

IEA

positive regulation of vasoconstriction

determination method

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35354

determination method

IEA

response to organonitrogen compound

determination method

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35354

determination method

IEA

inflammatory response

determination method

IEA

2 references

retrieved

9 May 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35354

determination method

IEA

retrieved

9 May 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35354

determination method

IEA

positive regulation of smooth muscle contraction

determination method

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35354

determination method

IEA

bone mineralization

determination method

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35354

determination method

IEA

response to fatty acid

determination method

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35354

determination method

IEA

response to vitamin D

determination method

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35354

determination method

IEA

cellular response to UV

determination method

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35354

determination method

IEA

positive regulation of fever generation

determination method

ISS

IEA

2 references

retrieved

9 May 2019

stated in

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35354

determination method

ISS

retrieved

9 May 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35354

determination method

IEA

cellular response to fluid shear stress

determination method

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35354

determination method

IEA

positive regulation of synaptic plasticity

determination method

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35354

determination method

IEA

regulation of blood pressure

determination method

ISS

IEA

3 references

retrieved

9 May 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P35354

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35354

determination method

ISS

retrieved

9 May 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35354

determination method

IEA

retrieved

9 May 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35354

determination method

IEA

response to lipopolysaccharide

determination method

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35354

determination method

IEA

positive regulation of platelet-derived growth factor production

determination method

ISS

IEA

2 references

retrieved

9 May 2019

stated in

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35354

determination method

ISS

retrieved

9 May 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35354

determination method

IEA

regulation of inflammatory response

determination method

NAS

1 reference

retrieved

9 May 2019

stated in

Expression and localization of cyclooxygenase‐1 and ‐2 in human sporadic amyotrophic lateral sclerosis

GOA

curator

UniProt

UniProt protein ID

P35354

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35354

determination method

NAS

brown fat cell differentiation

determination method

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35354

determination method

IEA

sensory perception of pain

determination method

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35354

determination method

IEA

response to radiation

determination method

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35354

determination method

IEA

prostaglandin biosynthetic process

determination method

NAS

ISS

IEA

5 references

retrieved

9 May 2019

stated in

Cyclooxygenase-2 controls energy homeostasis in mice by de novo recruitment of brown adipocytes

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35354

determination method

NAS

retrieved

9 May 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P35354

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35354

determination method

ISS

retrieved

9 May 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P35354

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35354

determination method

IEA

retrieved

9 May 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35354

determination method

IEA

retrieved

9 May 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35354

determination method

IEA

cellular response to ATP

determination method

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35354

determination method

IEA

ovulation

determination method

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35354

determination method

IEA

positive regulation of smooth muscle cell proliferation

determination method

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35354

determination method

IEA

hair cycle

determination method

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35354

determination method

IEA

response to estradiol

determination method

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35354

determination method

IEA

positive regulation of cell death

determination method

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35354

determination method

IEA

positive regulation of cell migration involved in sprouting angiogenesis

determination method

ISS

IEA

2 references

retrieved

9 May 2019

stated in

Cyclooxygenase regulates angiogenesis induced by colon cancer cells

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35354

determination method

ISS

retrieved

9 May 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35354

determination method

IEA

response to organic cyclic compound

determination method

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35354

determination method

IEA

lipid metabolism

determination method

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P35354

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35354

determination method

IEA

positive regulation of nitric oxide biosynthetic process

determination method

ISS

IEA

2 references

retrieved

9 May 2019

stated in

Cyclooxygenase regulates angiogenesis induced by colon cancer cells

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35354

determination method

ISS

retrieved

9 May 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35354

determination method

IEA

response to glucocorticoid

determination method

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35354

determination method

IEA

cyclooxygenase pathway

determination method

IDA

TAS

IEA

4 references

retrieved

9 May 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35354

determination method

TAS

retrieved

9 May 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35354

determination method

IEA

retrieved

9 May 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35354

determination method

IEA

retrieved

9 May 2019

stated in

Human cyclooxygenase-2 cDNA

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35354

determination method

IDA

fatty acid metabolic process

determination method

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P35354

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35354

determination method

IEA

positive regulation of fibroblast growth factor production

determination method

ISS

IEA

2 references

retrieved

9 May 2019

stated in

Cyclooxygenase regulates angiogenesis induced by colon cancer cells

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35354

determination method

ISS

retrieved

9 May 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35354

determination method

IEA

decidualization

determination method

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35354

determination method

IEA

regulation of cell population proliferation

determination method

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35354

determination method

IEA

positive regulation of cell population proliferation

determination method

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35354

determination method

IEA

negative regulation of calcium ion transport

determination method

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35354

determination method

IEA

positive regulation of apoptotic process

determination method

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35354

determination method

IEA

positive regulation of transforming growth factor beta production

determination method

ISS

IEA

2 references

retrieved

9 May 2019

stated in

Cyclooxygenase regulates angiogenesis induced by colon cancer cells

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35354

determination method

ISS

retrieved

9 May 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35354

determination method

IEA

positive regulation of vascular endothelial growth factor production

determination method

ISS

IEA

2 references

retrieved

9 May 2019

stated in

Cyclooxygenase regulates angiogenesis induced by colon cancer cells

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35354

determination method

ISS

retrieved

9 May 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35354

determination method

IEA

positive regulation of brown fat cell differentiation

determination method

ISS

IEA

2 references

retrieved

9 May 2019

stated in

Cyclooxygenase-2 controls energy homeostasis in mice by de novo recruitment of brown adipocytes

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35354

determination method

ISS

retrieved

9 May 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35354

determination method

IEA

negative regulation of synaptic transmission, dopaminergic

determination method

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35354

determination method

IEA

cellular oxidant detoxification

determination method

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

Gene Ontology Consortium

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35354

determination method

IEA

human ageing

determination method

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35354

determination method

IEA

NAD biosynthesis via nicotinamide riboside salvage pathway

determination method

TAS

1 reference

retrieved

9 May 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35354

determination method

TAS

cellular response to heat

determination method

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35354

determination method

IEA

positive regulation of prostaglandin biosynthetic process

determination method

IEA

NAS

2 references

retrieved

9 May 2019

stated in

Cyclooxygenase-2 controls energy homeostasis in mice by de novo recruitment of brown adipocytes

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35354

determination method

NAS

retrieved

9 May 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35354

determination method

IEA

positive regulation of peptidyl-serine phosphorylation

determination method

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35354

determination method

IEA

negative regulation of apoptotic process

determination method

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35354

determination method

IEA

negative regulation of cysteine-type endopeptidase activity involved in apoptotic process

determination method

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35354

determination method

IEA

cellular response to non-ionic osmotic stress

determination method

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35354

determination method

IEA

negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress

determination method

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35354

determination method

IEA

cellular response to lead ion

determination method

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35354

determination method

IEA

response to angiotensin

determination method

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35354

determination method

IEA

prostaglandin metabolic process

determination method

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P35354

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35354

determination method

IEA

positive regulation of protein import into nucleus

determination method

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35354

determination method

IEA

cytokine-mediated signaling pathway

determination method

TAS

1 reference

retrieved

9 May 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35354

determination method

TAS

long-chain fatty acid biosynthetic process

determination method

TAS

1 reference

retrieved

9 May 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35354

determination method

TAS

negative regulation of cell cycle

determination method

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35354

determination method

IEA

regulation of neuroinflammatory response

determination method

IEA

ISS

2 references

retrieved

9 May 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P35354

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35354

determination method

ISS

retrieved

9 May 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35354

determination method

IEA

physically interacts with

aspirin

has use

enzyme inhibitor

1 reference

stated in

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

4139

language of work or name

English

retrieved

17 August 2016

benzquinamide

has use

enzyme inhibitor

1 reference

stated in

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

7124

language of work or name

English

retrieved

17 August 2016

carprofen

has use

enzyme inhibitor

1 reference

stated in

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

7141

language of work or name

English

retrieved

17 August 2016

celecoxib

has use

enzyme inhibitor

1 reference

stated in

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

2892

language of work or name

English

retrieved

17 August 2016

Diclofenac

has use

enzyme inhibitor

1 reference

stated in

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

2714

language of work or name

English

retrieved

17 August 2016

(RS)-etodolac

has use

enzyme inhibitor

1 reference

stated in

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

7185

language of work or name

English

retrieved

17 August 2016

etoricoxib

has use

enzyme inhibitor

1 reference

stated in

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

2896

language of work or name

English

retrieved

17 August 2016

(+-)-flurbiprofen

has use

enzyme inhibitor

1 reference

stated in

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

4194

language of work or name

English

retrieved

17 August 2016

ibuprofen

has use

enzyme inhibitor

1 reference

stated in

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

2713

language of work or name

English

retrieved

17 August 2016

(RS)-ketoprofen

has use

enzyme inhibitor

1 reference

stated in

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

4795

language of work or name

English

retrieved

17 August 2016

ketorolac

has use

enzyme inhibitor

1 reference

stated in

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

6661

language of work or name

English

retrieved

17 August 2016

lumiracoxib

has use

enzyme inhibitor

1 reference

stated in

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

2897

language of work or name

English

retrieved

17 August 2016

meclofenamic acid

has use

enzyme inhibitor

1 reference

stated in

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

7219

language of work or name

English

retrieved

17 August 2016

mefenamic acid

has use

enzyme inhibitor

1 reference

stated in

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

2593

language of work or name

English

retrieved

17 August 2016

meloxicam

has use

enzyme inhibitor

1 reference

stated in

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

7220

language of work or name

English

retrieved

17 August 2016

naproxen

has use

enzyme inhibitor

1 reference

stated in

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

5230

language of work or name

English

retrieved

17 August 2016

nimesulide

has use

enzyme inhibitor

1 reference

stated in

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

7401

language of work or name

English

retrieved

17 August 2016

NS-398

has use

enzyme inhibitor

1 reference

stated in

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

8976

language of work or name

English

retrieved

17 August 2016

oxaprozin

has use

enzyme inhibitor

1 reference

stated in

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

7252

language of work or name

English

retrieved

17 August 2016

paracetamol

has use

enzyme inhibitor

1 reference

stated in

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

5239

language of work or name

English

retrieved

17 August 2016

phenylbutazone

has use

enzyme inhibitor

1 reference

stated in

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

7270

language of work or name

English

retrieved

17 August 2016

piroxicam

has use

enzyme inhibitor

1 reference

stated in

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

7273

language of work or name

English

retrieved

17 August 2016

resveratrol

has use

enzyme inhibitor

1 reference

stated in

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

8741

language of work or name

English

retrieved

17 August 2016

rofecoxib

has use

enzyme inhibitor

1 reference

stated in

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

2893

language of work or name

English

retrieved

17 August 2016

suprofen

has use

enzyme inhibitor

1 reference

stated in

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

7298

language of work or name

English

retrieved

17 August 2016

valdecoxib

has use

enzyme inhibitor

1 reference

stated in

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

2894

language of work or name

English

retrieved

17 August 2016

naproxen

object has role

reaction inhibitor

1 reference

stated in

Open Targets Platform

retrieved

14 August 2023

reference URL

https://platform.opentargets.org/drug/CHEMBL154

diclofenac sodium

object has role

reaction inhibitor

1 reference

stated in

Open Targets Platform

retrieved

14 August 2023

reference URL

https://platform.opentargets.org/drug/CHEMBL1034

iguratimod

object has role

reaction inhibitor

1 reference

stated in

Open Targets Platform

retrieved

14 August 2023

reference URL

https://platform.opentargets.org/drug/CHEMBL2107455

oxaprozin

object has role

reaction inhibitor

1 reference

stated in

Open Targets Platform

retrieved

14 August 2023

reference URL

https://platform.opentargets.org/drug/CHEMBL1071

apricoxib

object has role

reaction inhibitor

1 reference

stated in

Open Targets Platform

retrieved

14 August 2023

reference URL

https://platform.opentargets.org/drug/CHEMBL1835207

aspirin

object has role

reaction inhibitor

1 reference

stated in

Open Targets Platform

retrieved

14 August 2023

reference URL

https://platform.opentargets.org/drug/CHEMBL25

ibuprofen

object has role

reaction inhibitor

1 reference

stated in

Open Targets Platform

retrieved

14 August 2023

reference URL

https://platform.opentargets.org/drug/CHEMBL521

polmacoxib

object has role

reaction inhibitor

1 reference

stated in

Open Targets Platform

retrieved

14 August 2023

reference URL

https://platform.opentargets.org/drug/CHEMBL166863

ketorolac

object has role

reaction inhibitor

1 reference

stated in

Open Targets Platform

retrieved

14 August 2023

reference URL

https://platform.opentargets.org/drug/CHEMBL469

isoxicam

object has role

reaction inhibitor

1 reference

stated in

Open Targets Platform

retrieved

14 August 2023

reference URL

https://platform.opentargets.org/drug/CHEMBL53292

Diclofenac

object has role

reaction inhibitor

1 reference

stated in

Open Targets Platform

retrieved

14 August 2023

reference URL

https://platform.opentargets.org/drug/CHEMBL139

(RS)-etodolac

object has role

reaction inhibitor

1 reference

stated in

Open Targets Platform

retrieved

14 August 2023

reference URL

https://platform.opentargets.org/drug/CHEMBL622

bromfenac

object has role

reaction inhibitor

1 reference

stated in

Open Targets Platform

retrieved

14 August 2023

reference URL

https://platform.opentargets.org/drug/CHEMBL1077

(RS)-fenoprofen

object has role

reaction inhibitor

1 reference

stated in

Open Targets Platform

retrieved

14 August 2023

reference URL

https://platform.opentargets.org/drug/CHEMBL1297

diflunisal

object has role

reaction inhibitor

1 reference

stated in

Open Targets Platform

retrieved

14 August 2023

reference URL

https://platform.opentargets.org/drug/CHEMBL898

esflurbiprofen

object has role

reaction inhibitor

1 reference

stated in

Open Targets Platform

retrieved

14 August 2023

reference URL

https://platform.opentargets.org/drug/CHEMBL435298

diclofenac potassium

object has role

reaction inhibitor

1 reference

stated in

Open Targets Platform

retrieved

14 August 2023

reference URL

https://platform.opentargets.org/drug/CHEMBL1200804

(RS)-fenoprofen calcium dihydrate

object has role

reaction inhibitor

1 reference

stated in

Open Targets Platform

retrieved

14 August 2023

reference URL

https://platform.opentargets.org/drug/CHEMBL2103736

ketorolac tromethamine

object has role

reaction inhibitor

1 reference

stated in

Open Targets Platform

retrieved

14 August 2023

reference URL

https://platform.opentargets.org/drug/CHEMBL1201124

naproxen sodium

object has role

reaction inhibitor

1 reference

stated in

Open Targets Platform

retrieved

14 August 2023

reference URL

https://platform.opentargets.org/drug/CHEMBL1200806

tolmetin sodium

object has role

reaction inhibitor

1 reference

stated in

Open Targets Platform

retrieved

14 August 2023

reference URL

https://platform.opentargets.org/drug/CHEMBL1200613

EC enzyme number

1.14.99.1

0 references

exact match

http://purl.uniprot.org/uniprot/P35354

1 reference

stated in

Identifiers.org

has part(s)

EGF-like domain

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P35354

Commons category

Cyclooxygenase 2

0 references

Identifiers

NL CR AUT ID

ph430281

subject named as

cyklooxygenáza 2

0 references

RefSeq protein ID

NP_000954

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

5743

UniProt protein ID

P35354

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

P35354

Encyclopædia Britannica Online ID

science/cyclooxygenase-2

subject named as

cyclooxygenase-2

0 references

Ensembl protein ID

ENSP00000356438

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000356438

ENSP00000454130

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000454130

Freebase ID

/m/02x2zj9

1 reference

stated in

Freebase Data Dumps

publication date

28 October 2013

Microsoft Academic ID

2777350520

0 references

PDB structure ID

5F1A

1 reference

stated in

UniProt

UniProt protein ID

P35354

retrieved

9 August 2016

language of work or name

English

5F19

1 reference

stated in

UniProt

UniProt protein ID

P35354

retrieved

9 August 2016

language of work or name

English

5IKQ

1 reference

stated in

UniProt

UniProt protein ID

P35354

retrieved

9 August 2016

language of work or name

English

5IKT

1 reference

stated in

UniProt

UniProt protein ID

P35354

retrieved

9 August 2016

language of work or name

English

5IKV

1 reference

stated in

UniProt

UniProt protein ID

P35354

retrieved

9 August 2016

language of work or name

English

5IKR

1 reference

stated in

UniProt

UniProt protein ID

P35354

retrieved

9 August 2016

language of work or name

English

 

Sitelinks

Wikipedia(12 entries)

edit

• cywiki PTGS2
• dewiki Cyclooxygenase-2
• enwiki Cyclooxygenase-2
• eswiki PTGS2
• frwiki Cyclooxygénase 2
• glwiki Ciclooxixenase 2
• itwiki COX-2
• jawiki シクロオキシゲナーゼ2
• nlwiki Cyclo-oxygenase 2
• plwiki COX-2
• ptwiki COX-2
• ukwiki PTGS2

Wikibooks(0 entries)

edit

Wikinews(0 entries)

edit

Wikiquote(0 entries)

edit

Wikisource(0 entries)

edit

Wikiversity(0 entries)

edit

Wikivoyage(0 entries)

edit

Wiktionary(0 entries)

edit

Multilingual sites(1 entry)

edit

• commonswiki Category:Cyclooxygenase 2

Retrieved from "https://www.wikidata.org/w/index.php?title=Q415364&oldid=2129544697"