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Erb-b2 receptor tyrosine kinase 2 (Q415271)

From Wikidata
mammalian protein found in Homo sapiens
  • c-erb B2/neu protein
  • human epidermal growth factor receptor 2
  • tyrosine kinase-type cell surface receptor HER2
  • proto-oncogene Neu
  • v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog
  • MLN 19
  • receptor tyrosine-protein kinase erbB-2
  • neuroblastoma/glioblastoma derived oncogene homolog
  • v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2
  • herstatin
  • proto-oncogene c-ErbB-2
  • v-erb-b2 avian erythroblastic leukemia viral oncoprotein 2
  • ERBB2
  • p185erbB2
  • metastatic lymph node gene 19 protein
  • neuro/glioblastoma derived oncogene homolog
  • Receptor, ErbB-2
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    English
    Erb-b2 receptor tyrosine kinase 2
    mammalian protein found in Homo sapiens
    • c-erb B2/neu protein
    • human epidermal growth factor receptor 2
    • tyrosine kinase-type cell surface receptor HER2
    • proto-oncogene Neu
    • v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog
    • MLN 19
    • receptor tyrosine-protein kinase erbB-2
    • neuroblastoma/glioblastoma derived oncogene homolog
    • v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2
    • herstatin
    • proto-oncogene c-ErbB-2
    • v-erb-b2 avian erythroblastic leukemia viral oncoprotein 2
    • ERBB2
    • p185erbB2
    • metastatic lymph node gene 19 protein
    • neuro/glioblastoma derived oncogene homolog
    • Receptor, ErbB-2

    Statements

    part of
    molecular function
    protein binding
    determination method or standard
    IPI
    59 references
    retrieved
    8 April 2019
    stated in
    Dominance of ErbB-1 heterodimers in lung epithelial cells overexpressing ErbB-2. Both ErbB-1 and ErbB-2 contribute significantly to tumorigenicity
    GOA
    curator
    UniProt
    UniProt protein ID
    P04626
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04626
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Client Proteins and Small Molecule Inhibitors Display Distinct Binding Preferences for Constitutive and Stress-Induced HSP90 Isoforms and Their Conformationally Restricted Mutants
    GOA
    curator
    UniProt
    UniProt protein ID
    P04626
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04626
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Copine-III interacts with ErbB2 and promotes tumor cell migration
    GOA
    curator
    UniProt
    UniProt protein ID
    P04626
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04626
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Phosphotyrosine signaling networks in epidermal growth factor receptor overexpressing squamous carcinoma cells
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04626
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    A quantitative protein interaction network for the ErbB receptors using protein microarrays
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04626
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    IQGAP1 protein binds human epidermal growth factor receptor 2 (HER2) and modulates trastuzumab resistance
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04626
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Binding of Neu Differentiation Factor with the Extracellular Domain of Her2 and Her3
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04626
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    HER2 kinase domain mutation results in constitutive phosphorylation and activation of HER2 and EGFR and resistance to EGFR tyrosine kinase inhibitors
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04626
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Regulation of Hsp90 client proteins by a Cullin5-RING E3 ubiquitin ligase
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04626
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    ErbB2, EphrinB1, Src kinase and PTPN13 signaling complex regulates MAP kinase signaling in human cancers
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04626
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Tyrosine Phosphorylation of c-ErbB-2 Is Regulated by the Cellular Form of Prostatic Acid Phosphatase in Human Prostate Cancer Cells
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04626
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Recombinant human erythropoietin antagonizes trastuzumab treatment of breast cancer cells via Jak2-mediated Src activation and PTEN inactivation
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04626
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Cyanidin-3-Glucoside inhibits ethanol-induced invasion of breast cancer cells overexpressing ErbB2
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04626
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    A system for quantifying dynamic protein interactions defines a role for Herceptin in modulating ErbB2 interactions
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04626
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Quantitative analysis of HSP90-client interactions reveals principles of substrate recognition
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04626
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Brk is coamplified with ErbB2 to promote proliferation in breast cancer
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04626
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Progesterone receptor induces ErbB-2 nuclear translocation to promote breast cancer growth via a novel transcriptional effect: ErbB-2 function as a coactivator of Stat3
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04626
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Solution structure of the human Grb7-SH2 domain/erbB2 peptide complex and structural basis for Grb7 binding to ErbB2
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04626
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Growth stimulation of non-small cell lung cancer cell lines by antibody against epidermal growth factor receptor promoting formation of ErbB2/ErbB3 heterodimers
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04626
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Characterisation of HER heterodimers in breast cancer using in situ proximity ligation assay
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04626
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    The mammalian-membrane two-hybrid assay (MaMTH) for probing membrane-protein interactions in human cells
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04626
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Class II phosphoinositide 3-kinases are downstream targets of activated polypeptide growth factor receptors
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04626
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Oncogenic ERBB3 mutations in human cancers
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04626
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    HER2 phosphorylation is maintained by a PKB negative feedback loop in response to anti-HER2 herceptin in breast cancer
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04626
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Identification of a Src kinase SH3 binding site in the C-terminal domain of the human ErbB2 receptor tyrosine kinase
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04626
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Spontaneous and pronase-induced HER2 truncation increases the trastuzumab binding capacity of breast cancer tissues and cell lines
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04626
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Endosomal transport of ErbB-2: mechanism for nuclear entry of the cell surface receptor
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04626
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Nuclear ErbB2 enhances translation and cell growth by activating transcription of ribosomal RNA genes
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04626
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Secreted heat shock protein 90alpha induces colorectal cancer cell invasion through CD91/LRP-1 and NF-kappaB-mediated integrin alphaV expression
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04626
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Csk homologous kinase (CHK) and ErbB-2 interactions are directly coupled with CHK negative growth regulatory function in breast cancer
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04626
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    A quantitative chaperone interaction network reveals the architecture of cellular protein homeostasis pathways
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04626
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Functional isolation of activated and unilaterally phosphorylated heterodimers of ERBB2 and ERBB3 as scaffolds in ligand-dependent signaling
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04626
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Activation of ErbB2 by 2-methyl-1,4-naphthoquinone (menadione) in human keratinocytes: role of EGFR and protein tyrosine phosphatases
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04626
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Large-scale structural analysis of the classical human protein tyrosine phosphatome
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04626
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    The catalytic region and PEST domain of PTPN18 distinctly regulate the HER2 phosphorylation and ubiquitination barcodes
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04626
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Ligand-independent HER2/HER3/PI3K complex is disrupted by trastuzumab and is effectively inhibited by the PI3K inhibitor GDC-0941
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04626
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Structural determinants of the interaction between the erbB2 receptor and the Src homology 2 domain of Grb7
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04626
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Dominance of ErbB-1 heterodimers in lung epithelial cells overexpressing ErbB-2. Both ErbB-1 and ErbB-2 contribute significantly to tumorigenicity
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04626
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Activation of multiple proto-oncogenic tyrosine kinases in breast cancer via loss of the PTPN12 phosphatase
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04626
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Design, synthesis and characterization of peptidomimetic conjugate of BODIPY targeting HER2 protein extracellular domain
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04626
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    An activated ErbB3/NRG1 autocrine loop supports in vivo proliferation in ovarian cancer cells
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04626
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Assignment of backbone 1H, 13C, and 15N resonances of human Grb7-SH2 domain in complex with a phosphorylated peptide ligand
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04626
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Flow cytometric in situ proximity ligation analyses of protein interactions and post-translational modification of the epidermal growth factor receptor family
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04626
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Lyn, a Src family kinase, regulates activation of epidermal growth factor receptors in lung adenocarcinoma cells
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04626
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Parallel visualization of multiple protein complexes in individual cells in tumor tissue
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04626
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Pharmacological targeting of the pseudokinase Her3
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04626
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Systematic identification of molecular links between core and candidate genes in breast cancer
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04626
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Using an in Situ Proximity Ligation Assay to Systematically Profile Endogenous Protein–Protein Interactions in a Pathway Network
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04626
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    MEMO associated with an ErbB2 receptor phosphopeptide reveals a new phosphotyrosine motif
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04626
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    PI3K inhibition results in enhanced HER signaling and acquired ERK dependency in HER2-overexpressing breast cancer
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04626
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    The tumor suppressor RECK interferes with HER-2/Neu dimerization and attenuates its oncogenic signaling
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04626
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    ErbB-2 activates Stat3 alpha in a Src- and JAK2-dependent manner
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04626
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Paralog-selective Hsp90 inhibitors define tumor-specific regulation of HER2
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04626
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Perturbation of the mutated EGFR interactome identifies vulnerabilities and resistance mechanisms
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04626
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    The Atypical Histone MacroH2A1.2 Interacts with HER-2 Protein in Cancer Cells
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04626
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    ErbB2-mediated Src and signal transducer and activator of transcription 3 activation leads to transcriptional up-regulation of p21Cip1 and chemoresistance in breast cancer cells
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04626
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Charting the molecular links between driver and susceptibility genes in colorectal cancer
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04626
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Altered neuregulin 1-erbB4 signaling contributes to NMDA receptor hypofunction in schizophrenia
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04626
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    In situ quantification of HER2-protein tyrosine kinase 6 (PTK6) protein-protein complexes in paraffin sections from breast cancer tissues
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04626
    determination method or standard
    IPI
    identical protein binding
    determination method or standard
    IPI
    8 references
    retrieved
    8 April 2019
    stated in
    Comparative analysis of fluorescence resonance energy transfer (FRET) and proximity ligation assay (PLA)
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04626
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    The tumor suppressor RECK interferes with HER-2/Neu dimerization and attenuates its oncogenic signaling
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04626
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    HER2 kinase domain mutation results in constitutive phosphorylation and activation of HER2 and EGFR and resistance to EGFR tyrosine kinase inhibitors
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04626
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    HER2 phosphorylation is maintained by a PKB negative feedback loop in response to anti-HER2 herceptin in breast cancer
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04626
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    A system for quantifying dynamic protein interactions defines a role for Herceptin in modulating ErbB2 interactions
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04626
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Flow cytometric in situ proximity ligation analyses of protein interactions and post-translational modification of the epidermal growth factor receptor family
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04626
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Parallel visualization of multiple protein complexes in individual cells in tumor tissue
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04626
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Functional isolation of activated and unilaterally phosphorylated heterodimers of ERBB2 and ERBB3 as scaffolds in ligand-dependent signaling
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04626
    determination method or standard
    IPI
    cell component
    biological process
    physically interacts with
    Commons category
    ErbB-2 receptor
    0 references

    Identifiers

    MeSH descriptor ID
    D018719
    subject named as
    Receptor, ErbB-2
    0 references
    RefSeq protein ID
    PDB structure ID
     
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                  Retrieved from "https://www.wikidata.org/w/index.php?title=Q415271&oldid=2451078754"