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tylosin (Q411462)

From Wikidata
chemical compound
  • Tylosin A
  • Tylocine
  • Tylan
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    English
    tylosin
    chemical compound
    • Tylosin A
    • Tylocine
    • Tylan

    Statements

    chemical structure
    Tylosin structure.png
    1,242 × 665; 19 KB
    0 references
    chemical formula
    C₄₆H₇₇NO₁₇
    1 reference
    stated in
    PubChem
    PubChem CID
    5280440
    language of work or name
    English
    title
    Tylosin (English)
    retrieved
    19 November 2016
    canonical SMILES
    CCC1C(C=C(C=CC(=O)C(CC(C(C(C(CC(=O)O1)O)C)OC2C(C(C(C(O2)C)OC3CC(C(C(O3)C)O)(C)O)N(C)C)O)CC=O)C)C)COC4C(C(C(C(O4)C)O)OC)OC
    1 reference
    stated in
    PubChem
    PubChem CID
    5280440
    language of work or name
    English
    title
    Tylosin (English)
    retrieved
    19 November 2016
    isomeric SMILES
    CC[C@@H]1[C@H](/C=C(/C=C/C(=O)[C@@H](C[C@@H]([C@@H]([C@H]([C@@H](CC(=O)O1)O)C)O[C@H]2[C@@H]([C@H]([C@@H]([C@H](O2)C)O[C@H]3C[C@@]([C@H]([C@@H](O3)C)O)(C)O)N(C)C)O)CC=O)C)\C)CO[C@H]4[C@@H]([C@@H]([C@@H]([C@H](O4)C)O)OC)OC
    1 reference
    stated in
    PubChem
    PubChem CID
    5280440
    language of work or name
    English
    title
    Tylosin (English)
    retrieved
    19 November 2016
    found in taxon
    Streptomyces fradiae
    36 references
    stated in
    Molecular analysis of tlrD, an MLS resistance determinant from the tylosin producer, Streptomyces fradiae
    stated in
    Cloning of tlrD, a fourth resistance gene, from the tylosin producer, Streptomyces fradiae
    stated in
    The tylosin producer, Streptomyces fradiae, contains a second valine dehydrogenase
    stated in
    Valine dehydrogenase from Streptomyces fradiae: purification and properties
    stated in
    Impact of thioesterase activity on tylosin biosynthesis in Streptomyces fradiae
    stated in
    Amino acid catabolism and antibiotic synthesis: valine is a source of precursors for macrolide biosynthesis in Streptomyces ambofaciens and Streptomyces fradiae
    stated in
    Characterization and targeted disruption of a glycosyltransferase gene in the tylosin producer, Streptomyces fradiae
    stated in
    Genetic engineering of aminodeoxyhexose biosynthesis in Streptomyces fradiae
    stated in
    Relationship between threonine dehydratase and biosynthesis of tylosin in Streptomyces fradiae
    stated in
    Homology between proteins controlling Streptomyces fradiae tylosin resistance and ATP-binding transport
    stated in
    The tylosin-biosynthetic genes of Streptomyces fradiae
    stated in
    The mycarose-biosynthetic genes of Streptomyces fradiae, producer of tylosin
    stated in
    Fatty acids and production of tylosin-like compounds in Streptomyces fradiae
    stated in
    Metabolic regulation in tylosin-producing Streptomyces fradiae: phosphate control of tylosin biosynthesis
    stated in
    Properties of Streptomyces fradiae Mutants Blocked in Biosynthesis of the Macrolide Antibiotic Tylosin
    stated in
    Production of tylosin in solid-state fermentation by Streptomyces fradiae NRRL-2702 and its gamma-irradiated mutant (gamma-1).
    stated in
    The tylosin resistance gene tlrB of Streptomyces fradiae encodes a methyltransferase that targets G748 in 23S rRNA.
    stated in
    Transposition mutagenesis in Streptomyces fradiae: identification of a neutral site for the stable insertion of DNA by transposon exchange
    stated in
    The effect of dissolved oxygen and aeration rate on antibiotic production of Streptomyces fradiae
    stated in
    The mycinose-biosynthetic genes of Streptomyces fradiae, producer of tylosin
    stated in
    S-Adenosyl-L-methionine: macrocin O-methyltransferase activities in a series of Streptomyces fradiae mutants that produce different levels of the macrolide antibiotic tylosin
    stated in
    Synthesis of hydrolytic enzymes during production of tylosin byStreptomyces fradiae
    stated in
    Threonine dehydratases in different strains of Streptomyces fradiae
    stated in
    Kinetics of the repression of tylosin biosynthesis by ammonium ion in Streptomyces fradiae
    stated in
    Transcriptional attenuation control of the tylosin-resistance gene tlrA in Streptomyces fradiae
    stated in
    Characterization of mutations in regulatory genes of Tyl cluster leading to overexpression of tylosin in mutant γ-1 of Streptomyces fradiae NRRL-2702
    stated in
    High frequency conjugal transfer of tylosin genes and amplifiable DNA in Streptomyces fradiae
    stated in
    Influence of dimethylsulfoxide on tylosin production in Streptomyces fradiae
    stated in
    Effects of Rapeseed Oil on Activity of Methylmalonyl-CoA Carboxyltransferase in Culture ofStreptomyces fradiae
    stated in
    New tylosin analogs produced by mutants of Streptomyces fradiae
    stated in
    Biosynthesis of the macrolide antibiotic tylosin. Origin of the oxygen atoms in tylactone
    stated in
    Biosynthesis of Mycarose: Isolation and Characterization of Enzymes Involved in the C-2 Deoxygenation
    stated in
    The use of recombinant DNA techniques to study tylosin biosynthesis and resistance in Streptomyces fradiae
    stated in
    Branched-chain fatty acids produced by mutants of Streptomyces fradiae, putative precursors of the lactone ring of tylosin
    stated in
    Molecular Architecture of TylM1 from Streptomyces fradiae: An N,N-Dimethyltransferase Involved in the Production of dTDP-d-mycaminose,
    stated in
    Aspartate aminotransferase and tylosin biosynthesis in Streptomyces fradiae.
    mass
    915.519 dalton
    1 reference
    stated in
    PubChem
    PubChem CID
    5280440
    language of work or name
    English
    title
    Tylosin (English)
    retrieved
    19 October 2016
    Commons category
    Tylosin
    0 references

    Identifiers

    Reaxys registry number
    4651020
    1 reference
    stated in
    ChEBI
    ChEBI ID
    17658
    language of work or name
    English
    title
    tylosin (English)
    retrieved
    19 October 2016
    HSDB ID
    7022
    1 reference
    stated in
    Hazardous Substances Data Bank
    HSDB ID
    7022
    publication date
    28 October 2019
    title
    TYLOSIN (English)
    retrieved
    10 May 2021
    E number
    E713
    0 references
    KEGG ID
    D02490
    1 reference
    stated in
    ChEBI
    ChEBI ID
    17658
    language of work or name
    English
    title
    tylosin (English)
    retrieved
    19 October 2016
    PDB ligand ID
    TYK
    0 references
    YSO ID
    29501
    subject named as (monolingual text)
    tylosin (English)
    tylosiini (Finnish)
    tylosin (Swedish)
    tylosiidna (Northern Sami)
    1 reference
    stated in
    YSO-Wikidata mapping project
    retrieved
    9 August 2024
     
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