CD4/CD8 lineage commitment: back to instruction? (Q40994026)

25 September 2017

CD4/CD8 lineage commitment: back to instruction? (English)

1 reference

biomedical investigative technique

25 September 2017

1 reference

19 September 2019

1 reference

12 October 2019

hemic and immune systems

1 reference

PubMed

CD8-positive T-lymphocytes

18 October 2019

1 reference

8 April 2021

1 reference

von Boehmer H

1

1 reference

25 September 2017

1 March 1996

5 references

Journal of Experimental Medicine

25 September 2017

19 September 2019

12 October 2019

18 October 2019

8 April 2021

language of work or name

English

0 references

published in

5 references

25 September 2017

19 September 2019

12 October 2019

18 October 2019

8 April 2021

183

1 reference

25 September 2017

3

1 reference

25 September 2017

713-715

1 reference

PMC publication ID

2192339

publication type of scholarly work

25 September 2017

4 references

19 September 2019

12 October 2019

18 October 2019

8 April 2021

The cytoplasmic domain of CD4 promotes the development of CD4 lineage T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192339

Role of coreceptors in positive selection and lineage commitment

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192339

Stochastic component to development of class I major histocompatibility complex-specific T cells

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192339

Positive selection of T cells: rescue from programmed cell death and differentiation require continual engagement of the T cell receptor.

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192339

Intermediate steps in positive selection: differentiation of CD4+8int TCRint thymocytes into CD4-8+TCRhi thymocytes

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192339

Constitutive CD8 expression allows inefficient maturation of CD4+ helper T cells in class II major histocompatibility complex mutant mice

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192339

The CD4 and CD8 T cell surface antigens are associated with the internal membrane tyrosine-protein kinase p56lck

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192339

Signal for T-cell differentiation to a CD4 cell lineage is delivered by CD4 transmembrane region and/or cytoplasmic tail

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192339

Thymic selection of CD8+ single positive cells with a class II major histocompatibility complex-restricted receptor

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192339

Selective expression of an antigen receptor on CD8-bearing T lymphocytes in transgenic mice

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192339

Selective development of CD4+ T cells in transgenic mice expressing a class II MHC-restricted antigen receptor

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192339

Antigen/MHC-specific T cells are preferentially exported from the thymus in the presence of their MHC ligand.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192339

Thymic selection in CD8 transgenic mice supports an instructive model for commitment to a CD4 or CD8 lineage

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192339

Evidence for a stochastic mechanism in the differentiation of mature subsets of T lymphocytes.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192339

Another view of the selective model of thymocyte selection

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192339

A human CD4 transgene rescues CD4-CD8+ cells in beta 2-microglobulin-deficient mice

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192339

Functional commitment to helper T cell lineage precedes positive selection and is independent of T cell receptor MHC specificity

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192339

Evidence for lineage commitment and initiation of positive selection by thymocytes with intermediate surface phenotypes.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192339

Asymmetric signaling requirements for thymocyte commitment to the CD4+ versus CD8+ T cell lineages: a new perspective on thymic commitment and selection

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192339

Thymic major histocompatibility complex antigens and the αβ T-cell receptor determine the CD4/CD8 phenotype of T cells

19 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/8642273

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Evidence for a selective and multi-step model of T cell differentiation: CD4+CD8low thymocytes selected by a transgenic T cell receptor on major histocompatibility complex class I molecules

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/8642273

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1084/JEM.183.3.713

1 reference

25 September 2017

1 reference

PMC publication ID

2192339

25 September 2017

PubMed publication ID

8642273

1 reference

PMC publication ID

2192339