Coordinate regulation of B cell differentiation by the transcription factors EBF and E2A. (Q40937465)

25 September 2017

title

Coordinate regulation of B cell differentiation by the transcription factors EBF and E2A. (English)

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25 September 2017

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M O'Riordan

1

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25 September 2017

R Grosschedl

series ordinal

2

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25 September 2017

publication date

1 July 1999

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25 September 2017

language of work or name

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25 September 2017

volume

11

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25 September 2017

issue

1

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25 September 2017

page(s)

21-31

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Pax-5 encodes the transcription factor BSAP and is expressed in B lymphocytes, the developing CNS, and adult testis

25 September 2017

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E2A proteins are required for proper B cell development and initiation of immunoglobulin gene rearrangements

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An intermolecular disulfide bond stabilizes E2A homodimers and is required for DNA binding at physiological temperatures

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ALY, a context-dependent coactivator of LEF-1 and AML-1, is required for TCRalpha enhancer function

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Deregulation of PAX-5 by translocation of the Emu enhancer of the IgH locus adjacent to two alternative PAX-5 promoters in a diffuse large-cell lymphoma

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E47 activates the Ig-heavy chain and TdT loci in non-B cells.

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Collier, a novel regulator of Drosophila head development, is expressed in a single mitotic domain

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Pax-5 (BSAP) recruits Ets proto-oncogene family proteins to form functional ternary complexes on a B-cell-specific promoter

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Cloning and functional characterization of early B-cell factor, a regulator of lymphocyte-specific gene expression

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EBF contains a novel zinc coordination motif and multiple dimerization and transcriptional activation domains

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B-lineage differentiation stages resolved by multiparameter flow cytometry

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c-Myb and core-binding factor/PEBP2 display functional synergy but bind independently to adjacent sites in the T-cell receptor delta enhancer

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The promoter of the CD19 gene is a target for the B-cell-specific transcription factor BSAP

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Functional activity of myogenic HLH proteins requires hetero-oligomerization with E12/E47-like proteins in vivo

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The regulated expression of B lineage associated genes during B cell differentiation in bone marrow and fetal liver

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Failure of B-cell differentiation in mice lacking the transcription factor EBF.

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7 January 2021

Pax genes and their roles in cell differentiation and development

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Development and follicular localization of tolerant B lymphocytes in lysozyme/anti-lysozyme IgM/IgD transgenic mice

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Cooperative activation of muscle gene expression by MEF2 and myogenic bHLH proteins

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7 January 2021

RAG-1-deficient mice have no mature B and T lymphocytes

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7 January 2021

Interactions between heterologous helix-loop-helix proteins generate complexes that bind specifically to a common DNA sequence

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A new DNA binding and dimerization motif in immunoglobulin enhancer binding, daughterless, MyoD, and myc proteins

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7 January 2021

B-cell- and myocyte-specific E2-box-binding factors contain E12/E47-like subunits

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7 January 2021

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7 January 2021

Essential functions of Pax5 (BSAP) in pro-B cell development: difference between fetal and adult B lymphopoiesis and reduced V-to-DJ recombination at the IgH locus

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7 January 2021

Identification of BSAP (Pax-5) target genes in early B-cell development by loss- and gain-of-function experiments

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7 January 2021

Independent regulation of the two Pax5 alleles during B-cell development

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7 January 2021

Transcriptional regulation of B-cell differentiation

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7 January 2021

A subpopulation of B220+ cells in murine bone marrow does not express CD19 and contains natural killer cell progenitors

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7 January 2021

Helix-loop-helix transcription factor E47 activates germ-line immunoglobulin heavy-chain gene transcription and rearrangement in a pre-T-cell line

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7 January 2021

Requirement of transcription factor PU.1 in the development of multiple hematopoietic lineages

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7 January 2021

B-cell-specific DNA binding by an E47 homodimer

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7 January 2021

RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement

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7 January 2021

EBF and E47 collaborate to induce expression of the endogenous immunoglobulin surrogate light chain genes

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7 January 2021

Gene targeting reveals a hierarchy of transcription factors regulating specification of lymphoid cell fates

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7 January 2021

Phosphorylation of E47 as a potential determinant of B-cell-specific activity

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7 January 2021

Functional immunoglobulin transgenes guide ordered B-cell differentiation in Rag-1-deficient mice

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7 January 2021

Pax-5 is identical to EBB-1/KLP and binds to the VpreB and lambda5 promoters as well as the KI and KII sites upstream of the Jkappa genes

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7 January 2021

Aberrant B Cell Development and Immune Response in Mice with a Compromised BCR Complex

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7 January 2021

Complete block of early B cell differentiation and altered patterning of the posterior midbrain in mice lacking Pax5/BSAP

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7 January 2021

The B cell-specific transcription factor BSAP regulates B cell proliferation

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7 January 2021

Dependence of BSAP Repressor and Activator Functions on BSAP Concentration

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7 January 2021

Molecular cloning of the olfactory neuronal transcription factor Olf-1 by genetic selection in yeast

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7 January 2021

Cross-lineage expression of Ig-β (B29) in thymocytes: Positive and negative gene regulation to establish T cell identity

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7 January 2021

Gene Dosage–Dependent Embryonic Development and Proliferation Defects in Mice Lacking the Transcriptional Integrator p300

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https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980078-3

7 January 2021

The helix-loop-helix gene E2A is required for B cell formation

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980078-3

7 January 2021

10.1016/S1074-7613(00)80078-3

Identifiers

DOI

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25 September 2017

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