Ubiquitin-dependent degradation of TGF-beta-activated smad2. (Q40913405)

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2 November 2019

title

Ubiquitin-dependent degradation of TGF-beta-activated smad2 (English)

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2 November 2019

2

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2 November 2019

author name string

Lo RS

series ordinal

1

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2 November 2019

publication date

1 December 1999

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2 November 2019

language of work or name

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volume

1

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2 November 2019

issue

8

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2 November 2019

page(s)

472-478

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The transforming growth factor-beta family

2 November 2019

cites work

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Bone morphogenetic proteins: multifunctional regulators of vertebrate development

21 January 2018

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Smads and early developmental signaling by the TGFβ superfamily

21 January 2018

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TGF-beta signal transduction

21 January 2018

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TGF-β signalling from cell membrane to nucleus through SMAD proteins

21 January 2018

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Regulation of Smad signalling by protein associations and signalling crosstalk

21 January 2018

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TβRI Phosphorylation of Smad2 on Ser465 and Ser467 Is Required for Smad2-Smad4 Complex Formation and Signaling

21 January 2018

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Phosphorylation of Ser465 and Ser467 in the C Terminus of Smad2 Mediates Interaction with Smad4 and Is Required for Transforming Growth Factor-β Signaling

21 January 2018

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Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class I molecules

21 January 2018

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Inhibition of proteasome activities and subunit-specific amino-terminal threonine modification by lactacystin

21 January 2018

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Smad4 and FAST-1 in the assembly of activin-responsive factor

21 January 2018

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Dual role of the Smad4/DPC4 tumor suppressor in TGFbeta-inducible transcriptional complexes

21 January 2018

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Smad2 and Smad3 positively and negatively regulate TGF beta-dependent transcription through the forkhead DNA-binding protein FAST2

21 January 2018

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FAST-2 is a mammalian winged-helix protein which mediates transforming growth factor beta signals

21 January 2018

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A Smad transcriptional corepressor

21 January 2018

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A novel mesoderm inducer, Madr2, functions in the activin signal transduction pathway

21 January 2018

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A human Mad protein acting as a BMP-regulated transcriptional activator

21 January 2018

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Mutations increasing autoinhibition inactivate tumour suppressors Smad2 and Smad4

21 January 2018

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The ubiquitin-proteasome pathway: on protein death and cell life

21 January 2018

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Substrate targeting in the ubiquitin system

21 January 2018

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A multiubiquitin chain is confined to specific lysine in a targeted short-lived protein

21 January 2018

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MADR2 is a substrate of the TGFbeta receptor and its phosphorylation is required for nuclear accumulation and signaling

21 January 2018

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The TGF-beta family mediator Smad1 is phosphorylated directly and activated functionally by the BMP receptor kinase

21 January 2018

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Signal-induced ubiquitination of IkappaBalpha by the F-box protein Slimb/beta-TrCP

21 January 2018

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A ubiquitin ligase complex essential for the NF-kappaB, Wnt/Wingless, and Hedgehog signaling pathways

21 January 2018

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A SMAD ubiquitin ligase targets the BMP pathway and affects embryonic pattern formation

21 January 2018

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A mechanism of repression of TGFbeta/ Smad signaling by oncogenic Ras

21 January 2018

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The L3 loop: a structural motif determining specific interactions between SMAD proteins and TGF-beta receptors.

21 January 2018

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Identification of the ubiquitin carrier proteins, E2s, involved in signal-induced conjugation and subsequent degradation of IkappaBalpha

21 January 2018

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21 January 2018

Identifiers

DOI

10.1038/70258

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2 November 2019

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