SUMO-1 modification of Mdm2 prevents its self-ubiquitination and increases Mdm2 ability to ubiquitinate p53. (Q40868752)

24 September 2017

23 August 2002

3 references

Dataset for "Continued use of retracted papers: Temporal trends in citations and (lack of) awareness of retractions shown in citation contexts in biomedicine"

Continued use of retracted papers: Temporal trends in citations and (lack of) awareness of retractions shown in citation contexts in biomedicine

19 August 2025

SUMO-1 modification of Mdm2 prevents its self-ubiquitination and increases Mdm2 ability to ubiquitinate p53. (English)

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24 September 2017

main subject

protein ubiquitination

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T Buschmann

1

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24 September 2017

S Y Fuchs

2

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24 September 2017

C G Lee

3

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24 September 2017

Z Q Pan

4

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24 September 2017

Z Ronai

5

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24 September 2017

publication date

1 June 2000

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24 September 2017

language of work or name

0 references

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24 September 2017

volume

101

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24 September 2017

issue

7

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24 September 2017

page(s)

753-762

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mdm2 expression is induced by wild type p53 activity

24 September 2017

cites work

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https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980887-9

7 January 2021

Mapping of the p53 and mdm-2 Interaction Domains

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https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980887-9

7 January 2021

mdm-2 inhibits the G1 arrest and apoptosis functions of the p53 tumor suppressor protein

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980887-9

7 January 2021

The conserved RING-H2 finger of ROC1 is required for ubiquitin ligation

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980887-9

7 January 2021

SCF and Cullin/Ring H2-based ubiquitin ligases

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980887-9

7 January 2021

SUMO-1 modification of IkappaBalpha inhibits NF-kappaB activation

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980887-9

7 January 2021

Mdm2 is a RING finger-dependent ubiquitin protein ligase for itself and p53

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https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980887-9

7 January 2021

Mdm2 association with p53 targets its ubiquitination

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https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980887-9

7 January 2021

Differential regulation of sentrinized proteins by a novel sentrin-specific protease

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https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980887-9

7 January 2021

Activation of p53 by conjugation to the ubiquitin-like protein SUMO-1.

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https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980887-9

7 January 2021

Mdm2 promotes the rapid degradation of p53

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https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980887-9

7 January 2021

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980887-9

1 reference

7 January 2021

Oncoprotein MDM2 is a ubiquitin ligase E3 for tumor suppressor p53

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980887-9

7 January 2021

Association of p19(ARF) with Mdm2 inhibits ubiquitin ligase activity of Mdm2 for tumor suppressor p53.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980887-9

7 January 2021

Activity of MDM2, a ubiquitin ligase, toward p53 or itself is dependent on the RING finger domain of the ligase

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980887-9

7 January 2021

Covalent modification of all members of human cullin family proteins by NEDD8

1 reference

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7 January 2021

Mammalian homologs of seven in absentia regulate DCC via the ubiquitin–proteasome pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980887-9

7 January 2021

A family of proteins structurally and functionally related to the E6-AP ubiquitin-protein ligase

1 reference

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7 January 2021

A new protease required for cell-cycle progression in yeast

1 reference

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7 January 2021

Ubc9p Is the Conjugating Enzyme for the Ubiquitin-like Protein Smt3p

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980887-9

7 January 2021

Cell cycle-regulated attachment of the ubiquitin-related protein SUMO to the yeast septins

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980887-9

7 January 2021

The ubiquitin-like protein Smt3p is activated for conjugation to other proteins by an Aos1p/Uba2p heterodimer

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980887-9

7 January 2021

Rescue of embryonic lethality in Mdm2-deficient mice by absence of p53

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980887-9

7 January 2021

Functional and physical interactions of the ARF tumor suppressor with p53 and Mdm2

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980887-9

7 January 2021

Characterization of NEDD8, a Developmentally Down-regulated Ubiquitin-like Protein

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980887-9

7 January 2021

Identification of Three Major Sentrinization Sites in PML

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980887-9

7 January 2021

The Rbx1 subunit of SCF and VHL E3 ubiquitin ligase activates Rub1 modification of cullins Cdc53 and Cul2

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980887-9

7 January 2021

Regulation of p53 stability by Mdm2

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980887-9

7 January 2021

Modification of yeast Cdc53p by the ubiquitin-related protein rub1p affects function of the SCFCdc4 complex

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980887-9

7 January 2021

Ubiquitin ligase activity and tyrosine phosphorylation underlie suppression of growth factor signaling by c-Cbl/Sli-1

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980887-9

7 January 2021

Covalent modification of the transcriptional repressor tramtrack by the ubiquitin-related protein Smt3 in Drosophila flies

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980887-9

7 January 2021

Conjugation of the ubiquitin-like protein NEDD8 to cullin-2 is linked to von Hippel-Lindau tumor suppressor function

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980887-9

7 January 2021

RING fingers mediate ubiquitin-conjugating enzyme (E2)-dependent ubiquitination

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980887-9

7 January 2021

A small ubiquitin-related polypeptide involved in targeting RanGAP1 to nuclear pore complex protein RanBP2

1 reference

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7 January 2021

Identification of determinants in E2 ubiquitin-conjugating enzymes required for hect E3 ubiquitin-protein ligase interaction

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980887-9

7 January 2021

p76(MDM2) inhibits the ability of p90(MDM2) to destabilize p53.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980887-9

7 January 2021

Nedd8 modification of cul-1 activates SCF(beta(TrCP))-dependent ubiquitination of IkappaBalpha

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980887-9

7 January 2021

SUMO-1 modification activates the transcriptional response of p53

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980887-9

7 January 2021

Characterization of Human hect Domain Family Members and Their Interaction with UbcH5 and UbcH7

1 reference

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7 January 2021

Stabilization of the MDM2 oncoprotein by interaction with the structurally related MDMX protein

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980887-9

7 January 2021

DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980887-9

7 January 2021

DNA damage induces phosphorylation of the amino terminus of p53

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980887-9

7 January 2021

The nuclear dot protein sp100, characterization of domains necessary for dimerization, subcellular localization, and modification by small ubiquitin-like modifiers

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980887-9

7 January 2021

Recruitment of a ROC1-CUL1 ubiquitin ligase by Skp1 and HOS to catalyze the ubiquitination of I kappa B alpha

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980887-9

7 January 2021

Ubiquitin-dependent c-Jun degradation in vivo is mediated by the delta domain

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980887-9

7 January 2021

The SCF(HOS/beta-TRCP)-ROC1 E3 ubiquitin ligase utilizes two distinct domains within CUL1 for substrate targeting and ubiquitin ligation

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980887-9

7 January 2021

Whose end is destruction: cell division and the anaphase-promoting complex

1 reference

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7 January 2021

10.1016/S0092-8674(00)80887-9

Identifiers

DOI

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24 September 2017

1 reference