Formation and repair of DNA lesions in thep53 gene: Relation to cancer mutations? (Q40859486)

24 September 2017

title

Formation and repair of DNA lesions in the p53 gene: relation to cancer mutations? (English)

1 reference

24 September 2017

Formation and repair of DNA lesions in thep53 gene: Relation to cancer mutations? (English)

1 reference

10.1002/(SICI)1098-2280(1998)31:3<197::AID-EM1>3.0.CO;2-I

https://api.crossref.org/works/10.1002/(SICI)1098-2280(1998)31:3%3C197::AID-EM1%3E3.0.CO;2-I

21 December 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9585258

21 December 2024

DNA repair

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9585258

21 December 2024

TP53

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9585258

21 December 2024

author name string

G. P. Pfeifer

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9585258

21 December 2024

M. F. Denissenko

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9585258

21 December 2024

publication date

1 January 1998

1 reference

24 September 2017

1998

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=9585258

https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2F(SICI)1098-2280(1998)31:3%3C197::AID-EM1%3E3.0.CO;2-I

21 December 2024

language of work or name

English

1 reference

based on heuristic

inferred from title

work available at URL

1 reference

10.1002/(SICI)1098-2280(1998)31:3<197::AID-EM1>3.0.CO;2-I

https://api.crossref.org/works/10.1002/(SICI)1098-2280(1998)31:3%3C197::AID-EM1%3E3.0.CO;2-I

https://onlinelibrary.wiley.com/doi/full/10.1002/(SICI)1098-2280(1998)31:3%3C197::AID-EM1%3E3.0.CO;2-I

21 December 2024

1 reference

10.1002/(SICI)1098-2280(1998)31:3<197::AID-EM1>3.0.CO;2-I

https://api.crossref.org/works/10.1002/(SICI)1098-2280(1998)31:3%3C197::AID-EM1%3E3.0.CO;2-I

Environmental and Molecular Mutagenesis

21 December 2024

published in

1 reference

24 September 2017

volume

31

1 reference

24 September 2017

issue

3

1 reference

24 September 2017

page(s)

197-205

1 reference

publication type of scholarly work

24 September 2017

review article

1 reference

Aflatoxin B1 induces the transversion of G-->T in codon 249 of the p53 tumor suppressor gene in human hepatocytes

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Mutational properties of the primary aflatoxin B1-DNA adduct

21 January 2018

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21 January 2018

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A proteolytic fragment from the central region of p53 has marked sequence-specific DNA-binding activity when generated from wild-type but not from oncogenic mutant p53 protein

21 January 2018

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p53 gene mutation: software and database.

21 January 2018

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Does a genotoxic carcinogen contribute to human breast cancer? The value of mutational spectra in unravelling the aetiology of cancer.

21 January 2018

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Dominant-negative p53 mutations selected in yeast hit cancer hot spots

21 January 2018

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A role for sunlight in skin cancer: UV-induced p53 mutations in squamous cell carcinoma

21 January 2018

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Selective G to T mutations of p53 gene in hepatocellular carcinoma from southern Africa

21 January 2018

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TP53 tumor suppressor gene: a model for investigating human mutagenesis

21 January 2018

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Effect of excision repair by diploid human fibroblasts on the kinds and locations of mutations induced by (+/-)-7 beta,8 alpha-dihydroxy-9 alpha,10 alpha-epoxy-7,8,9,10- tetrahydrobenzo[a]pyrene in the coding region of the HPRT gene

21 January 2018

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Preferential repair and strand-specific repair of benzo[a]pyrene diol epoxide adducts in the HPRT gene of diploid human fibroblasts

21 January 2018

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Crystal structure of a p53 tumor suppressor-DNA complex: understanding tumorigenic mutations

21 January 2018

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Preferential formation of benzo[a]pyrene adducts at lung cancer mutational hotspots in P53.

21 January 2018

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Cytosine methylation determines hot spots of DNA damage in the human P53 gene

21 January 2018

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Gain of function mutations in p53.

21 January 2018

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Formation of Cyclobutane dimers and (6-4) Photoproducts upon Far-UV Photolysis of 5-Methylcytosine-Containing Dinucleoside Monophosphates

21 January 2018

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Specific UV-induced mutation spectrum in the p53 gene of skin tumors from DNA-repair-deficient xeroderma pigmentosum patients

21 January 2018

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Can we predict solar ultraviolet radiation as the causal event in human tumours by analysing the mutation spectra of the p53 gene?

21 January 2018

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Carcinogenic epoxides of benzo[a]pyrene and cyclopenta[cd]pyrene induce base substitutions via specific transversions

21 January 2018

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Participation of p53 cellular tumour antigen in transformation of normal embryonic cells

21 January 2018

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The p53 proto-oncogene can act as a suppressor of transformation

21 January 2018

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A simple p53 functional assay for screening cell lines, blood, and tumors

21 January 2018

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Preferential repair of ultraviolet light-induced DNA damage in the transcribed strand of the human p53 gene

21 January 2018

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DNA repair rates mapped along the human PGK1 gene at nucleotide resolution

21 January 2018

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Mutagenic and epigenetic effects of DNA methylation

21 January 2018

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Database of p53 gene somatic mutations in human tumors and cell lines: updated compilation and future prospects

21 January 2018

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p53: at the crossroads of molecular carcinogenesis and risk assessment

21 January 2018

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The 1995 Walter Hubert Lecture--molecular epidemiology of human cancer: insights from the mutational analysis of the p53 tumour-suppressor gene

21 January 2018

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The molecular epidemiology of p53 gene mutations in human breast cancer

21 January 2018

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Carcinogen biomarkers related to smoking and upper aerodigestive tract cancer

21 January 2018

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Somatic point mutations in the p53 gene of human tumors and cell lines: updated compilation

21 January 2018

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Mutational hot spot in the p53 gene in human hepatocellular carcinomas

21 January 2018

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The Major, N2-Gua Adduct of the (+)-anti-Benzo[a]pyrene Diol Epoxide Is Capable of Inducing G.fwdarw.A and G.fwdarw.C, in Addition to G.fwdarw.T, Mutations

21 January 2018

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Monoallelically Expressed Gene Related to p53 at 1p36, a Region Frequently Deleted in Neuroblastoma and Other Human Cancers

21 January 2018

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21 January 2018

p53: puzzle and paradigm

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P53 mutations associated with breast, colorectal, liver, lung, and ovarian cancers

21 January 2018

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The spectrum of mutations at the p53 locus. Evidence for tissue-specific mutagenesis, selection of mutant alleles, and a "gain of function" phenotype

21 January 2018

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Sequence specificity of mutations induced by benzo[a]pyrene-7,8-diol-9,10-epoxide at endogenous aprt gene in CHO cells

21 January 2018

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Selective removal of transcription-blocking DNA damage from the transcribed strand of the mammalian DHFR gene

21 January 2018

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Cloning and expression of human G/T mismatch-specific thymine-DNA glycosylase

21 January 2018

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Sequence specificity in CpG mutation hotspots

21 January 2018

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In vivo mapping of a DNA adduct at nucleotide resolution: detection of pyrimidine (6-4) pyrimidone photoproducts by ligation-mediated polymerase chain reaction

21 January 2018

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Binding of transcription factors creates hot spots for UV photoproducts in vivo

21 January 2018

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Detection of DNA adducts at the DNA sequence level by ligation-mediated PCR

21 January 2018

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DNA adducts in human tissues: biomarkers of exposure to carcinogens in tobacco smoke.

21 January 2018

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5-Methylcytosine as an Endogenous Mutagen in the Human LDL Receptor and p53 Genes

21 January 2018

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Benzo[a]pyrene-induced murine skin tumors exhibit frequent and characteristic G to T mutations in the p53 gene

21 January 2018

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The Wavelengths in Sunlight Effective in Producing Skin Cancer: A Theoretical Analysis

21 January 2018

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The factor IX gene as a model for analysis of human germline mutations: an update

21 January 2018

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Structural aspects of the p53 protein in relation to gene evolution: a second look.

21 January 2018

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Slow repair of pyrimidine dimers at p53 mutation hotspots in skin cancer

21 January 2018

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Potential effects of altered solar ultraviolet radiation on human skin cancer

21 January 2018

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Site-specific rates of excision repair of benzo[a]pyrene diol epoxide adducts in the hypoxanthine phosphoribosyltransferase gene of human fibroblasts: correlation with mutation spectra

21 January 2018

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The rate of CpG mutation in Alu repetitive elements within the p53 tumor suppressor gene in the primate germline

21 January 2018

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Mutation hotspots due to sunlight in the p53 gene of nonmelanoma skin cancers.

21 January 2018

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Association between cigarette smoking and mutation of the p53 gene in squamous-cell carcinoma of the head and neck

21 January 2018

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The role of UV-B light in skin carcinogenesis through the analysis of p53 mutations in squamous cell carcinomas of hairless mice

21 December 2024

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p53: a glimpse at the puppet behind the shadow play

21 December 2024

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Conformational shifts propagate from the oligomerization domain of p53 to its tetrameric DNA binding domain and restore DNA binding to select p53 mutants.

21 December 2024

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A mutant p53 transgene accelerates tumour development in heterozygous but not nullizygous p53-deficient mice

21 December 2024

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In vivo evidence that UV-induced C-->T mutations at dipyrimidine sites could result from the replicative bypass of cis-syn cyclobutane dimers or their deamination products

21 December 2024

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Mutagenic specificity of ultraviolet light

21 December 2024

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Analysis of the most representative tumour-derived p53 mutants reveals that changes in protein conformation are not correlated with loss of transactivation or inhibition of cell proliferation.

21 December 2024

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Mutations of the p53 tumor suppressor gene and ras oncogenes in aflatoxin hepatocarcinogenesis.

21 December 2024

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Silent and multiple mutations in p53 and the question of the hypermutability of tumors

21 December 2024

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Differences and similarities in the repair of two benzo[a]pyrene diol epoxide isomers induced DNA adducts by uvrA, uvrB, and uvrC gene products

21 December 2024

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10.1002/(SICI)1098-2280(1998)31:3<197::AID-EM1>3.0.CO;2-I

https://api.crossref.org/works/10.1002/(SICI)1098-2280(1998)31:3%3C197::AID-EM1%3E3.0.CO;2-I

21 December 2024

X-rays strike p53 again

88

1 reference

10.1002/(SICI)1098-2280(1998)31:3<197::AID-EM1>3.0.CO;2-I

https://api.crossref.org/works/10.1002/(SICI)1098-2280(1998)31:3%3C197::AID-EM1%3E3.0.CO;2-I

Changes in DNA base sequence induced by targeted mutagenesis of lambda phage by ultraviolet light

21 December 2024

90

1 reference

10.1002/(SICI)1098-2280(1998)31:3<197::AID-EM1>3.0.CO;2-I

https://api.crossref.org/works/10.1002/(SICI)1098-2280(1998)31:3%3C197::AID-EM1%3E3.0.CO;2-I

21 December 2024

Identifiers

10.1002/(SICI)1098-2280(1998)31:3<197::AID-EM1>3.0.CO;2-I

1 reference

24 September 2017

1 reference