Bcl-2 is an apoptotic target suppressed by both c-Myc and E2F-1 (Q40769247)

23 September 2017

title

Bcl-2 is an apoptotic target suppressed by both c-Myc and E2F-1 (English)

1 reference

DOI

10.1038/SJ.ONC.1204892

https://api.crossref.org/works/10.1038/SJ.ONC.1204892

27 January 2025

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A11704823

27 January 2025

author name string

C. M. Eischen

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A11704823

27 January 2025

G. Packham

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A11704823

27 January 2025

J. Nip

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A11704823

27 January 2025

B. E. Fee

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A11704823

27 January 2025

S. W. Hiebert

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A11704823

27 January 2025

G. P. Zambetti

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A11704823

27 January 2025

J. L. Cleveland

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A11704823

27 January 2025

publication date

1 October 2001

1 reference

23 September 2017

25 October 2001

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=11704823

27 January 2025

language of work or name

0 references

1 reference

23 September 2017

volume

20

1 reference

23 September 2017

issue

48

1 reference

23 September 2017

page(s)

6983-6993

1 reference

p14ARF links the tumour suppressors RB and p53

23 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204892

The Max network gone mad.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204892

Apoptotic cell death induced by c-myc is inhibited by bcl-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204892

Induction of cell cycle progression and acceleration of apoptosis are two separable functions of c-Myc: transrepression correlates with acceleration of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204892

Disruption of the ARF-Mdm2-p53 tumor suppressor pathway in Myc-induced lymphomagenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204892

Apoptosis triggered by Myc-induced suppression of Bcl-X(L) or Bcl-2 is bypassed during lymphomagenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204892

Induction of apoptosis in fibroblasts by c-myc protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204892

Cooperative interaction between c-myc and bcl-2 proto-oncogenes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204892

v-Myb of E26 leukemia virus up-regulates bcl-2 and suppresses apoptosis in myeloid cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204892

Induction of growth arrest by a temperature-sensitive p53 mutant is correlated with increased nuclear localization and decreased stability of the protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204892

The Myc/Max/Mad network and the transcriptional control of cell behavior

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204892

bcl-x exhibits regulated expression during B cell development and activation and modulates lymphocyte survival in transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204892

BCL-2 family members and the mitochondria in apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204892

The Rb/E2F pathway: expanding roles and emerging paradigms

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204892

Regulation of cell proliferation by the E2F transcription factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204892

Mediation of c-Myc-induced apoptosis by p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204892

E2F-1:DP-1 induces p53 and overrides survival factors to trigger apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204892

E2F1-induced apoptosis requires DNA binding but not transactivation and is inhibited by the retinoblastoma protein through direct interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204892

The anti-apoptosis function of Bcl-2 can be genetically separated from its inhibitory effect on cell cycle entry

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204892

Multiple docking sites on substrate proteins form a modular system that mediates recognition by ERK MAP kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204892

Expression of transcription factor E2F1 induces quiescent cells to enter S phase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204892

c-Myc-induced sensitization to apoptosis is mediated through cytochrome c release

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204892

Tumor suppression at the mouse INK4a locus mediated by the alternative reading frame product p19ARF

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204892

Direct binding of cyclin D to the retinoblastoma gene product (pRb) and pRb phosphorylation by the cyclin D-dependent kinase CDK4

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204892

A link between c-Myc-mediated transcriptional repression and neoplastic transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204892

The PIM-1 serine kinase prolongs survival and inhibits apoptosis-related mitochondrial dysfunction in part through a bcl-2-dependent pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204892

A modified oestrogen receptor ligand-binding domain as an improved switch for the regulation of heterologous proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204892

Positive and negative regulation of cell proliferation by E2F-1: influence of protein level and human papillomavirus oncoproteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204892

Targeted disruption of Bcl-2 alpha beta in mice: occurrence of gray hair, polycystic kidney disease, and lymphocytopenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204892

E2F-1 induces the stabilization of p53 but blocks p53-mediated transactivation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204892

E2F-1 cooperates with topoisomerase II inhibition and DNA damage to selectively augment p53-independent apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204892

Apoptosis and cell division

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204892

Ornithine decarboxylase is a mediator of c-Myc-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204892

Induction of ornithine decarboxylase by IL-3 is mediated by sequential c-Myc-independent and c-Myc-dependent pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204892

Selective regulation ofBcl-XLby a Jak kinase-dependent pathway is bypassed in murine hematopoietic malignancies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204892

Induction of DNA synthesis and apoptosis are separable functions of E2F-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204892

Mechanisms of apoptosis by c-Myc

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204892

c-myc antisense transcripts accelerate differentiation and inhibit G1 progression in murine erythroleukemia cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204892

Deregulated transcription factor E2F-1 expression leads to S-phase entry and p53-mediated apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204892

Alternative reading frames of the INK4a tumor suppressor gene encode two unrelated proteins capable of inducing cell cycle arrest

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204892

p19 Arf induces p53-dependent apoptosis during Abelson virus-mediated pre-B cell transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204892

Direct role for Myc in transcription initiation mediated by interactions with TFII-I

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204892

Involvement of Myc activity in a G(1)/S-promoting mechanism parallel to the pRb/E2F pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204892

INK4a/ARF mutations accelerate lymphomagenesis and promote chemoresistance by disabling p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204892

Deregulated expression of E2F-1 induces S-phase entry and leads to apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204892

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204892

Novel primitive lymphoid tumours induced in transgenic mice by cooperation between myc and bcl-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204892

A dominant interfering Myb mutant causes apoptosis in T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204892

Bcl-2 gene promotes haemopoietic cell survival and cooperates with c-myc to immortalize pre-B cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204892

Bcl-2-deficient mice demonstrate fulminant lymphoid apoptosis, polycystic kidneys, and hypopigmented hair

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204892

Myc-mediated apoptosis requires wild-type p53 in a manner independent of cell cycle arrest and the ability of p53 to induce p21waf1/cip1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204892

Transactivation-defective c-MycS retains the ability to regulate proliferation and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204892

Myc signaling via the ARF tumor suppressor regulates p53-dependent apoptosis and immortalization

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204892

p19ARF links the tumour suppressor p53 to Ras

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204892

myc oncogenes: activation and amplification

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204892

7 January 2021

The MYC protein activates transcription of the alpha-prothymosin gene.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204892

7 January 2021

Down-regulation of bcl-2 is associated with p16INK4-mediated apoptosis in non-small cell lung cancer cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204892

7 January 2021

E2F1 overexpression in quiescent fibroblasts leads to induction of cellular DNA synthesis and apoptosis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204892

7 January 2021

c-Myc represses transcription in vivo by a novel mechanism dependent on the initiator element and Myc box II

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204892

7 January 2021

Massive cell death of immature hematopoietic cells and neurons in Bcl-x-deficient mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204892

7 January 2021

The E2F transcription factors: key regulators of cell proliferation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204892

7 January 2021

Genetic dissection of c-myc apoptotic pathways

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204892

7 January 2021

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204892

1 reference

7 January 2021

Bmi-1 collaborates with c-Myc in tumorigenesis by inhibiting c-Myc-induced apoptosis via INK4a/ARF.

26

1 reference

DOI

10.1038/SJ.ONC.1204892

https://api.crossref.org/works/10.1038/SJ.ONC.1204892

27 January 2025

Identifiers

DOI

10.1038/SJ.ONC.1204892

1 reference

Dimensions publication ID

23 September 2017

1002423828

0 references

1 reference