Cellular radiosensitivity in ataxia-telangiectasia (Q40580197)

4 February 2018

title

Cellular radiosensitivity in ataxia-telangiectasia (English)

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4 February 2018

author name string

J Thacker

series ordinal

1

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4 February 2018

publication date

1 January 1994

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4 February 2018

International Journal of Radiation Biology

language of work or name

English

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published in

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4 February 2018

volume

66

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4 February 2018

issue

sup6

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4 February 2018

page(s)

S87-S96

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4 February 2018

p53 binds single-stranded DNA ends and catalyzes DNA renaturation and strand transfer.

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Comparison of gamma-radiation-induced accumulation of ataxia telangiectasia and control cells in G2 phase

21 January 2018

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Fibroblasts from ataxia telangiectasia (AT) and AT heterozygotes show an enhanced level of residual DNA double-strand breaks after low dose-rate gamma-irradiation as assayed by pulsed field gel electrophoresis

21 January 2018

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Hypersensitivity of lymphoblastoid lines derived from ataxia telangiectasia patients to the induction of chromosomal aberrations by etoposide (VP-16).

21 January 2018

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Thymocyte apoptosis induced by p53-dependent and independent pathways

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Response of radiation-sensitive human cells to defined DNA breaks

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Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

21 January 2018

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p53-dependent inhibition of cyclin-dependent kinase activities in human fibroblasts during radiation-induced G1 arrest.

21 January 2018

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Unusual levels of (ADP-ribose)n and DNA synthesis in ataxia telangiectasia cells following gamma-ray irradiation

21 January 2018

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The effects of ionizing radiation on cell cycle progression in ataxia telangiectasia

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DNA double-strand breaks: their repair and relationship to cell killing in yeast

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Repair and misrepair of site-specific DNA double-strand breaks by human cell extracts

21 January 2018

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The DNA-dependent protein kinase: requirement for DNA ends and association with Ku antigen

21 January 2018

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Defects in a cell cycle checkpoint may be responsible for the genomic instability of cancer cells

21 January 2018

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Effect of ionizing radiation on DNA synthesis in ataxia telangiectasia cells.

21 January 2018

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Isolation and cross-sensitivity of X-ray-sensitive mutants of V79-4 hamster cells

21 January 2018

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Biochemical and genetic analysis of the Chinese hamster mutants irs1 and irs2 and their comparison to cultured ataxia telangiectasia cells

21 January 2018

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Stable radioresistance in ataxia-telangiectasia cells containing DNA from normal human cells

21 January 2018

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Modification of deoxyribose-phosphate residues by extracts of ataxia telangiectasia cells

21 January 2018

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A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia

21 January 2018

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Inhibition of replicon initiation in human cells following stabilization of topoisomerase-DNA cleavable complexes

21 January 2018

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G1 arrest and cell-cycle-dependent clastogenesis in UV-irradiated human fibroblasts

21 January 2018

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Mutagenesis by apurinic sites in normal and ataxia telangiectasia human lymphoblastoid cells

21 January 2018

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p53 mutations increase resistance to ionizing radiation

21 January 2018

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Human cells contain a DNA-activated protein kinase that phosphorylates simian virus 40 T antigen, mouse p53, and the human Ku autoantigen

21 January 2018

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Hybrid T cell receptor genes formed by interlocus recombination in normal and ataxia-telangiectasis lymphocytes

21 January 2018

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The ionizing radiation-induced replication protein A phosphorylation response differs between ataxia telangiectasia and normal human cells

21 January 2018

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p53 is required for radiation-induced apoptosis in mouse thymocytes

21 January 2018

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Differential induction of transcriptionally active p53 following UV or ionizing radiation: defects in chromosome instability syndromes?

21 January 2018

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Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms

21 January 2018

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High spontaneous intrachromosomal recombination rates in ataxia-telangiectasia

21 January 2018

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Ataxia-telangiectasia: an inherited disorder of ionizing-radiation sensitivity in man. Progress in the elucidation of the underlying biochemical defect

21 January 2018

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Creative blocks: cell-cycle checkpoints and feedback controls

21 January 2018

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Comparison of kinetics of X-ray-induced cell killing in normal, ataxia telangiectasia and hereditary retinoblastoma fibroblasts

21 January 2018

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DNA strand breaks: the DNA template alterations that trigger p53-dependent DNA damage response pathways

21 January 2018

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The rejoining of double-strand breaks in DNA by human cell extracts

21 January 2018

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https://api.crossref.org/works/10.1080%2F09553009414551911

Inhibition and recovery of DNA synthesis in human cells after exposure to ultraviolet light

21 January 2018

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Radiosensitivity in ataxia-telangiectasia: a new explanation

21 January 2018

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Flow cytometric analysis of X-ray sensitivity in ataxia telangiectasia

21 January 2018

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Abnormal processing of transfected plasmid DNA in cells from patients with ataxia telangiectasia

21 January 2018

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Feedback controls and G2 checkpoints: fission yeast as a model system

21 January 2018

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RAD9-dependent G1 arrest defines a second checkpoint for damaged DNA in the cell cycle of Saccharomyces cerevisiae

21 January 2018

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Mutation spectrum in gamma-irradiated shuttle vector replicated in ataxia-telangiectasia lymphoblasts

21 January 2018

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Reduced DNA topoisomerase II activity in ataxia-telangiectasia cells

21 January 2018

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Enhanced sensitivity to camptothecin in ataxia-telangiectasia cells and its relationship with the expression of DNA topoisomerase I.

21 January 2018

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Cell-Cycle-Dependent Repair of Potentially Lethal Damage in the XR-1 γ-Ray-Sensitive Chinese Hamster Ovary Cell

21 January 2018

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Impairment of V(D)J recombination in double-strand break repair mutants

21 January 2018

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Analysis of mutations caused by DNA double-strand breaks produced by a restriction enzyme in shuttle vector plasmids propagated in ataxia telangiectasia cells

21 January 2018

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Unrepaired DNA strand breaks in irradiated ataxia telangiectasia lymphocytes suggested from cytogenetic observations

21 January 2018

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Genetic and cellular features of ataxia telangiectasia

21 January 2018

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Differences in the DNA Supercoiling Response of Irradiated Cell Lines from Ataxia-telangiectasia Versus Unaffected Individuals

21 January 2018

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A mechanism for deletion formation in DNA by human cell extracts: the involvement of short sequence repeats

21 January 2018

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https://api.crossref.org/works/10.1080%2F09553009414551911

DNA-break repair, radioresistance of DNA synthesis, and camptothecin sensitivity in the radiation-sensitive irs mutants: comparisons to ataxia-telangiectasia cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09553009414551911

Responses of 4 X-ray-sensitive CHO cell mutants to different radiations and to irradiation conditions promoting cellular recovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09553009414551911

Co-dominance of radioresistant DNA synthesis in a group of AT-like Chinese hamster cell mutants

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09553009414551911

The RAD9 gene controls the cell cycle response to DNA damage in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09553009414551911

Characterization of RAD9 of Saccharomyces cerevisiae and evidence that its function acts posttranslationally in cell cycle arrest after DNA damage

21 January 2018

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https://api.crossref.org/works/10.1080%2F09553009414551911

Mitotic checkpoint genes in budding yeast and the dependence of mitosis on DNA replication and repair

21 January 2018

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Programmed cell death: apoptosis and oncogenesis.

21 January 2018

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https://api.crossref.org/works/10.1080%2F09553009414551911

Mutagen-sensitive cell lines are obtained with a high frequency in V79 Chinese hamster cells

21 January 2018

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https://api.crossref.org/works/10.1080%2F09553009414551911

Delayed Initiation of DNA Synthesis in Irradiated Human Diploid Cells

21 January 2018

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https://api.crossref.org/works/10.1080%2F09553009414551911

Ataxia telangiectasia: a human mutation with abnormal radiation sensitivity

21 January 2018

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https://api.crossref.org/works/10.1080%2F09553009414551911

Deficient recovery from potentially lethal radiation damage in ataxia telangiectasia and xeroderma pigmentosum

21 January 2018

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10.1080/09553009414551911

21 January 2018

Identifiers

DOI

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4 February 2018

7836857

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4 February 2018