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Enhanced caspase-8 recruitment to and activation at the DISC is critical for sensitisation of human hepatocellular carcinoma cells to TRAIL-induced apoptosis by chemotherapeutic drugs. (Q40563380)

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scientific article published on July 2004

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English	Enhanced caspase-8 recruitment to and activation at the DISC is critical for sensitisation of human hepatocellular carcinoma cells to TRAIL-induced apoptosis by chemotherapeutic drugs.	scientific article published on July 2004

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27 December 2019

Enhanced caspase-8 recruitment to and activation at the DISC is critical for sensitisation of human hepatocellular carcinoma cells to TRAIL-induced apoptosis by chemotherapeutic drugs (English)

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27 December 2019

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hepatocellular carcinoma

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27 December 2019

Martin R. Sprick

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27 December 2019

Wolfgang Stremmel

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27 December 2019

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T M Ganten

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27 December 2019

J Sykora

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27 December 2019

H Stahl

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27 December 2019

S C Fas

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A Krueger

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27 December 2019

M A Weigand

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A Grosse-Wilde

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27 December 2019

P H Krammer

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27 December 2019

H Walczak

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27 December 2019

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1 July 2004

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27 December 2019

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Cell Death & Differentiation

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27 December 2019

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27 December 2019

S86-96

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27 December 2019

Identification and characterization of a new member of the TNF family that induces apoptosis

1 reference

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Tumoricidal activity of tumor necrosis factor-related apoptosis-inducing ligand in vivo.

1 reference

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21 January 2018

Is TRAIL hepatotoxic?

1 reference

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Safety and antitumor activity of recombinant soluble Apo2 ligand

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Tumoricidal activity of a novel anti-human DR5 monoclonal antibody without hepatocyte cytotoxicity.

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The receptor for the cytotoxic ligand TRAIL

1 reference

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21 January 2018

Characterization of two receptors for TRAIL1

1 reference

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TRAIL-R2: a novel apoptosis-mediating receptor for TRAIL.

1 reference

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21 January 2018

Control of TRAIL-Induced Apoptosis by a Family of Signaling and Decoy Receptors

1 reference

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KILLER/DR5 is a DNA damage-inducible p53-regulated death receptor gene

1 reference

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21 January 2018

TRICK2, a new alternatively spliced receptor that transduces the cytotoxic signal from TRAIL

1 reference

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21 January 2018

Identification and Molecular Cloning of Two Novel Receptors for the Cytotoxic Ligand TRAIL

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CD95's deadly mission in the immune system

1 reference

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Cloning and characterization of TRAIL-R3, a novel member of the emerging TRAIL receptor family

1 reference

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21 January 2018

TRUNDD, a new member of the TRAIL receptor family that antagonizes TRAIL signalling

1 reference

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The novel receptor TRAIL-R4 induces NF-kappaB and protects against TRAIL-mediated apoptosis, yet retains an incomplete death domain

1 reference

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Osteoprotegerin Is a Receptor for the Cytotoxic Ligand TRAIL

1 reference

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21 January 2018

FADD/MORT1 and caspase-8 are recruited to TRAIL receptors 1 and 2 and are essential for apoptosis mediated by TRAIL receptor 2

1 reference

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21 January 2018

Apo2L/TRAIL-dependent recruitment of endogenous FADD and caspase-8 to death receptors 4 and 5.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401437

21 January 2018

TRAIL receptor-2 signals apoptosis through FADD and caspase-8

1 reference

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21 January 2018

Caspase-10 is recruited to and activated at the native TRAIL and CD95 death-inducing signalling complexes in a FADD-dependent manner but can not functionally substitute caspase-8.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401437

21 January 2018

Death receptor recruitment of endogenous caspase-10 and apoptosis initiation in the absence of caspase-8

1 reference

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21 January 2018

Synergistic induction of apoptosis by the combination of trail and chemotherapy in chemoresistant ovarian cancer cells

1 reference

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21 January 2018

Apoptosis and drug response

1 reference

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21 January 2018

Mechanisms of resistance of normal cells to TRAIL induced apoptosis vary between different cell types

1 reference

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21 January 2018

TRAIL and inhibitors of apoptosis are opposing determinants for NF-kappaB-dependent, genotoxin-induced apoptosis of cancer cells

1 reference

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21 January 2018

Identification of X-linked inhibitor of apoptosis-associated factor-1 as an interferon-stimulated gene that augments TRAIL Apo2L-induced apoptosis

1 reference

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21 January 2018

Resistance of mitochondrial DNA-deficient cells to TRAIL: role of Bax in TRAIL-induced apoptosis

1 reference

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21 January 2018

c-FLIP(L) is a dual function regulator for caspase-8 activation and CD95-mediated apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401437

21 January 2018

Cellular FLICE-inhibitory protein splice variants inhibit different steps of caspase-8 activation at the CD95 death-inducing signaling complex

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401437

21 January 2018

Inhibition of death receptor signals by cellular FLIP

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401437

21 January 2018

The bile acid glycochenodeoxycholate induces trail-receptor 2/DR5 expression and apoptosis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401437

21 January 2018

Evidence that the death receptor DR4 is a DNA damage-inducible, p53-regulated gene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401437

21 January 2018

Death and decoy receptors and p53-mediated apoptosis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401437

21 January 2018

TRAIL-induced apoptosis requires Bax-dependent mitochondrial release of Smac/DIABLO

1 reference

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21 January 2018

Proteasome inhibition results in TRAIL sensitization of primary keratinocytes by removing the resistance-mediating block of effector caspase maturation

1 reference

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21 January 2018

Inhibition of TRAIL-induced apoptosis by Bcl-2 overexpression

1 reference

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21 January 2018

The short splice form of Casper/c-FLIP is a major cellular inhibitor of TRAIL-induced apoptosis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401437

21 January 2018

Viral FLICE-inhibitory proteins (FLIPs) prevent apoptosis induced by death receptors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401437

21 January 2018

The role of c-FLIP in modulation of CD95-induced apoptosis

1 reference

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21 January 2018

Modulation of tumor necrosis factor apoptosis-inducing ligand- induced NF-kappa B activation by inhibition of apical caspases

1 reference

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21 January 2018

Intracellular mechanisms of TRAIL: apoptosis through mitochondrial-dependent and -independent pathways

1 reference

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21 January 2018

Intracellular mechanisms of TRAIL and its role in cancer therapy

1 reference

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21 January 2018

Mechanisms of resistance to TRAIL-induced apoptosis in primary B cell chronic lymphocytic leukaemia.

1 reference

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21 January 2018

FLICE is predominantly expressed as two functionally active isoforms, caspase-8/a and caspase-8/b.

1 reference

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A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry

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RNA interference-mediated silencing of the S100A10 gene attenuates plasmin generation and invasiveness of Colo 222 colorectal cancer cells.

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Apoptosis induced in normal human hepatocytes by tumor necrosis factor-related apoptosis-inducing ligand

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Differential hepatocyte toxicity of recombinant Apo2L/TRAIL versions

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401437

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1 reference

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Biochemistry and function of the DISC

1 reference

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Sensitization of resistant lymphoma cells to irradiation-induced apoptosis by the death ligand TRAIL

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TNF-related apoptosis-inducing ligand-induced apoptosis of melanoma is associated with changes in mitochondrial membrane potential and perinuclear clustering of mitochondria

1 reference

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1 reference

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Chemotherapeutic agents augment TRAIL-induced apoptosis in human hepatocellular carcinoma cell lines

1 reference

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On the TRAIL from p53 to apoptosis?

1 reference

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Smac agonists sensitize for Apo2L/TRAIL- or anticancer drug-induced apoptosis and induce regression of malignant glioma in vivo

1 reference

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1 reference

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10.1038/SJ.CDD.4401437

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27 December 2019

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27 December 2019

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