Knockouts. Targeting the mouse genome: a compendium of knockouts (Part I) (Q40409394)

20 September 2017

title

Knockouts. Targeting the mouse genome: a compendium of knockouts (Part I) (English)

1 reference

20 September 2017

Brandon EP

1

1 reference

20 September 2017

Idzerda RL

series ordinal

2

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20 September 2017

McKnight GS

series ordinal

3

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20 September 2017

publication date

1 June 1995

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20 September 2017

language of work or name

English

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number of pages

10

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inferred from page(s)

published in

Current Biology

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20 September 2017

volume

5

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20 September 2017

issue

6

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20 September 2017

page(s)

625-634

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publication type of scholarly work

20 September 2017

review article

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Altering the genome by homologous recombination

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Gene Targeting in ES Cells

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Swaying is a mutant allele of the proto-oncogene Wnt-1

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Mice with a null mutation of the TGF alpha gene have abnormal skin architecture, wavy hair, and curly whiskers and often develop corneal inflammation.

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7 January 2021

TGF alpha deficiency results in hair follicle and eye abnormalities in targeted and waved-1 mice

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7 January 2021

Loss of fumarylacetoacetate hydrolase is responsible for the neonatal hepatic dysfunction phenotype of lethal albino mice.

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7 January 2021

FGF5 as a regulator of the hair growth cycle: evidence from targeted and spontaneous mutations

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7 January 2021

Interaction of endothelin-3 with endothelin-B receptor is essential for development of epidermal melanocytes and enteric neurons

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7 January 2021

Targeted and natural (piebald-lethal) mutations of endothelin-B receptor gene produce megacolon associated with spotted coat color in mice

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7 January 2021

Colorectal hyperplasia and inflammation in keratin 8-deficient FVB/N mice

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7 January 2021

Hoxb-4 (Hox-2.6) mutant mice show homeotic transformation of a cervical vertebra and defects in the closure of the sternal rudiments

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7 January 2021

Genetic background alters the spectrum of tumors that develop in p53-deficient mice

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7 January 2021

Hyperuricemia and urate nephropathy in urate oxidase-deficient mice

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7 January 2021

Germ-line transmission of a c-abl mutation produced by targeted gene disruption in ES cells

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7 January 2021

Mice homozygous for the ablm1 mutation show poor viability and depletion of selected B and T cell populations

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7 January 2021

Neonatal lethality and lymphopenia in mice with a homozygous disruption of the c-abl proto-oncogene

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7 January 2021

Impaired long-term potentiation, spatial learning, and hippocampal development in fyn mutant mice

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7 January 2021

Abnormal avoidance learning in mice lacking functional high-affinity nicotine receptor in the brain

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7 January 2021

Functional analysis of activins during mammalian development.

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7 January 2021

Activin/inhibin beta B subunit gene disruption leads to defects in eyelid development and female reproduction

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7 January 2021

Different phenotypes for mice deficient in either activins or activin receptor type II

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7 January 2021

A targeted chain-termination mutation in the mouse Apc gene results in multiple intestinal tumors

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2895%2900127-8

7 January 2021

Altered behavior and long-term potentiation in type I adenylyl cyclase mutant mice

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2895%2900127-8

7 January 2021

Degeneration of neural cells in the central nervous system of mice deficient in the gene for the adhesion molecule on Glia, the beta 2 subunit of murine Na,K-ATPase

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2895%2900127-8

7 January 2021

Behavioral and anatomical deficits in mice homozygous for a modified beta-amyloid precursor protein gene

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2895%2900127-8

7 January 2021

Marked reduction of high density lipoprotein cholesterol in mice genetically modified to lack apolipoprotein A-I

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7 January 2021

Lack of apoA-I is not associated with increased susceptibility to atherosclerosis in mice

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https://api.crossref.org/works/10.1016%2FS0960-9822%2895%2900127-8

7 January 2021

Targeted modification of the apolipoprotein B gene results in hypobetalipoproteinemia and developmental abnormalities in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2895%2900127-8

7 January 2021

Knockout of the mouse apolipoprotein B gene results in embryonic lethality in homozygotes and protection against diet-induced hypercholesterolemia in heterozygotes

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2895%2900127-8

7 January 2021

Severe hypercholesterolemia and atherosclerosis in apolipoprotein E-deficient mice created by homologous recombination in ES cells

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2895%2900127-8

7 January 2021

Spontaneous hypercholesterolemia and arterial lesions in mice lacking apolipoprotein E

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2895%2900127-8

7 January 2021

Generation of mice carrying a mutant apolipoprotein E gene inactivated by gene targeting in embryonic stem cells

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2895%2900127-8

7 January 2021

Human apolipoprotein A-I gene expression increases high density lipoprotein and suppresses atherosclerosis in the apolipoprotein E-deficient mouse

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2895%2900127-8

7 January 2021

ApoE-deficient mice develop lesions of all phases of atherosclerosis throughout the arterial tree

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2895%2900127-8

7 January 2021

Nerve regeneration occurs in the absence of apolipoprotein E in mice

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7 January 2021

Apolipoprotein AI transgene corrects apolipoprotein E deficiency-induced atherosclerosis in mice

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7 January 2021

Diet-induced atherosclerosis in mice heterozygous and homozygous for apolipoprotein E gene disruption

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7 January 2021

Prevention of atherosclerosis in apolipoprotein E-deficient mice by bone marrow transplantation

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7 January 2021

Generation of a mouse model for citrullinemia by targeted disruption of the argininosuccinate synthetase gene

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7 January 2021

Genetic decreases in atrial natriuretic peptide and salt-sensitive hypertension

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2895%2900127-8

7 January 2021

Complete block of early B cell differentiation and altered patterning of the posterior midbrain in mice lacking Pax5/BSAP

1 reference

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7 January 2021

Uncovering of Functional Alternative CTLA-4 Counter-Receptor in B7-Deficient Mice

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7 January 2021

Bcl-2-deficient mice demonstrate fulminant lymphoid apoptosis, polycystic kidneys, and hypopigmented hair

1 reference

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7 January 2021

Targeted disruption of Bcl-2 alpha beta in mice: occurrence of gray hair, polycystic kidney disease, and lymphocytopenia

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7 January 2021

Massive cell death of immature hematopoietic cells and neurons in Bcl-x-deficient mice

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7 January 2021

Posterior transformation, neurological abnormalities, and severe hematopoietic defects in mice with a targeted deletion of the bmi-1 proto-oncogene

1 reference

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7 January 2021

Mice lacking brain-derived neurotrophic factor develop with sensory deficits

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2895%2900127-8

7 January 2021

Targeted disruption of the BDNF gene perturbs brain and sensory neuron development but not motor neuron development.

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2895%2900127-8

7 January 2021

E-cadherin null mutant embryos fail to form a trophectoderm epithelium

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2895%2900127-8

7 January 2021

A targeted mutation in the mouse E-cadherin gene results in defective preimplantation development

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2895%2900127-8

7 January 2021

Impaired spatial learning in alpha-calcium-calmodulin kinase II mutant mice

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2895%2900127-8

7 January 2021

Deficient hippocampal long-term potentiation in alpha-calcium-calmodulin kinase II mutant mice

1 reference

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7 January 2021

Abnormal fear response and aggressive behavior in mutant mice deficient for alpha-calcium-calmodulin kinase II.

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7 January 2021

The role of calcium-calmodulin kinase II in three forms of synaptic plasticity

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7 January 2021

Milk composition and lactation of beta-casein-deficient mice.

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7 January 2021

Regulated expression of human CD4 rescues helper T cell development in mice lacking expression of endogenous CD4.

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7 January 2021

Normal development and function of CD8+ cells but markedly decreased helper cell activity in mice lacking CD4

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https://api.crossref.org/works/10.1016%2FS0960-9822%2895%2900127-8

7 January 2021

Helper T cells without CD4: control of leishmaniasis in CD4-deficient mice

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7 January 2021

Helper T-cell development in the absence of CD4-p56 Ick association

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7 January 2021

CD4+ T-lymphocytes are not required for murine resistance to the human filarial parasite, Brugia malayi

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7 January 2021

CD4 expression is differentially required for deletion of MLS-1a-reactive T cells.

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7 January 2021

Experimental allergic encephalomyelitis (EAE) in mice lacking CD4+ T cells

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7 January 2021

Class II major histocompatibility complex-restricted T cell function in CD4-deficient mice

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7 January 2021

Enhanced establishment of a virus carrier state in adult CD4+ T-cell-deficient mice.

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7 January 2021

Human CD4 restores normal T cell development and function in mice deficient in murine CD4.

1 reference

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7 January 2021

Maternal transfer of infectious mouse mammary tumor retroviruses does not depend on clonal deletion of superantigen-reactive V beta 14+ T cells

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https://api.crossref.org/works/10.1016%2FS0960-9822%2895%2900127-8

7 January 2021

CD8 is needed for development of cytotoxic T cells but not helper T cells

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2895%2900127-8

7 January 2021

CD45RA and CD45RBhigh expression induced by thymic selection events

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7 January 2021

Less mortality but more relapses in experimental allergic encephalomyelitis in CD8-/- mice

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7 January 2021

The lack of CD8 alpha cytoplasmic domain resulted in a dramatic decrease in efficiency in thymic maturation but only a moderate reduction in cytotoxic function of CD8+ T lymphocytes

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https://api.crossref.org/works/10.1016%2FS0960-9822%2895%2900127-8

7 January 2021

Thymic selection of cytotoxic T cells independent of CD8 alpha-Lck association

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7 January 2021

CD8 is needed for positive selection but differentially required for negative selection of T cells during thymic ontogeny

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7 January 2021

CD8 is critically involved in lymphocyte activation by a T. brucei brucei-released molecule

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7 January 2021

Characteristics of fetal thymus-derived T cell receptor gamma delta intestinal intraepithelial lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2895%2900127-8

7 January 2021

Reduced thymic maturation but normal effector function of CD8+ T cells in CD8 beta gene-targeted mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2895%2900127-8

7 January 2021

The absence of IgE antibody-mediated augmentation of immune responses in CD23-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2895%2900127-8

7 January 2021

Differential T cell costimulatory requirements in CD28-deficient mice

1 reference

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7 January 2021

Humoral immune responses in CD40 ligand-deficient mice

1 reference

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7 January 2021

Normal B lymphocyte development but impaired T cell maturation in CD45-exon6 protein tyrosine phosphatase-deficient mice

1 reference

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7 January 2021

Leukocyte common antigen (CD45) is required for immunoglobulin E-mediated degranulation of mast cells

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2895%2900127-8

7 January 2021

The cellular retinoic acid binding protein I is dispensable.

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2895%2900127-8

7 January 2021

Disruption of the CNTF gene results in motor neuron degeneration

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2895%2900127-8

7 January 2021

Mice lacking alpha 1 (IX) collagen develop noninflammatory degenerative joint disease

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2895%2900127-8

7 January 2021

Targeted mutation in the col5a2 gene reveals a regulatory role for type V collagen during matrix assembly

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2895%2900127-8

7 January 2021

Normal long bone growth and development in type X collagen-null mice

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2895%2900127-8

7 January 2021

Cardiac malformation in neonatal mice lacking connexin43.

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2895%2900127-8

7 January 2021

Corticotropin-releasing hormone deficiency reveals major fetal but not adult glucocorticoid need

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2895%2900127-8

7 January 2021

Skeletal muscles of mice deficient in muscle creatine kinase lack burst activity

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2895%2900127-8

7 January 2021

Creatine kinase (CK) in skeletal muscle energy metabolism: a study of mouse mutants with graded reduction in muscle CK expression

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2895%2900127-8

7 January 2021

Effects of the creatine analogue beta-guanidinopropionic acid on skeletal muscles of mice deficient in muscle creatine kinase

1 reference

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7 January 2021

Disruption of the csk gene, encoding a negative regulator of Src family tyrosine kinases, leads to neural tube defects and embryonic lethality in mice

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https://api.crossref.org/works/10.1016%2FS0960-9822%2895%2900127-8

7 January 2021

Constitutive activation of Src family kinases in mouse embryos that lack Csk.

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2895%2900127-8

7 January 2021

Targeted mutation of the CREB gene: compensation within the CREB/ATF family of transcription factors.

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2895%2900127-8

7 January 2021

Deficient long-term memory in mice with a targeted mutation of the cAMP-responsive element-binding protein.

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2895%2900127-8

7 January 2021

Mice deficient in cystathionine beta-synthase: animal models for mild and severe homocyst(e)inemia

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2895%2900127-8

7 January 2021

Production of a severe cystic fibrosis mutation in mice by gene targeting

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https://api.crossref.org/works/10.1016%2FS0960-9822%2895%2900127-8

7 January 2021

An animal model for cystic fibrosis made by gene targeting

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https://api.crossref.org/works/10.1016%2FS0960-9822%2895%2900127-8

7 January 2021

Defective epithelial chloride transport in a gene-targeted mouse model of cystic fibrosis

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2895%2900127-8

7 January 2021

A severe phenotype in mice with a duplication of exon 3 in the cystic fibrosis locus.

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2895%2900127-8

7 January 2021

Inactivation of the murine cftr gene abolishes cAMP-mediated but not Ca(2+)-mediated secretagogue-induced volume decrease in small-intestinal crypts

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2895%2900127-8

7 January 2021

Chloride secretion in response to guanylin in colonic epithelial from normal and transgenic cystic fibrosis mice

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2895%2900127-8

7 January 2021

Correction of the ion transport defect in cystic fibrosis transgenic mice by gene therapy

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2895%2900127-8

7 January 2021

CFTR and outward rectifying chloride channels are distinct proteins with a regulatory relationship

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2895%2900127-8

7 January 2021

Correction of lethal intestinal defect in a mouse model of cystic fibrosis by human CFTR

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2895%2900127-8

7 January 2021

Inefficient gene transfer by adenovirus vector to cystic fibrosis airway epithelia of mice and humans

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2895%2900127-8

7 January 2021

Cystic Fibrosis Heterozygote Resistance to Cholera Toxin in the Cystic Fibrosis Mouse Model

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2895%2900127-8

7 January 2021

Cystic fibrosis in the mouse by targeted insertional mutagenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2895%2900127-8

7 January 2021

CFTR and calcium-activated chloride currents in pancreatic duct cells of a transgenic CF mouse

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2895%2900127-8

7 January 2021

Long-term survival of the exon 10 insertional cystic fibrosis mutant mouse is a consequence of low level residual wild-type Cftr gene expression

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2895%2900127-8

7 January 2021

Lung disease in the cystic fibrosis mouse exposed to bacterial pathogens

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2895%2900127-8

7 January 2021

Targeted mutation of the DNA methyltransferase gene results in embryonic lethality

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2895%2900127-8

7 January 2021

Role for DNA methylation in genomic imprinting

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2895%2900127-8

7 January 2021

Deletion of a DNA polymerase beta gene segment in T cells using cell type-specific gene targeting

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2895%2900127-8

7 January 2021

Dopamine D1 receptor mutant mice are deficient in striatal expression of dynorphin and in dopamine-mediated behavioral responses

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2895%2900127-8

7 January 2021

Altered striatal function in a mutant mouse lacking D1A dopamine receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2895%2900127-8

7 January 2021

Elimination of cocaine-induced hyperactivity and dopamine-mediated neurophysiological effects in dopamine D1 receptor mutant mice

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https://api.crossref.org/works/10.1016%2FS0960-9822%2895%2900127-8

7 January 2021

The helix-loop-helix gene E2A is required for B cell formation

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https://api.crossref.org/works/10.1016%2FS0960-9822%2895%2900127-8

7 January 2021

E2A proteins are required for proper B cell development and initiation of immunoglobulin gene rearrangements

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2895%2900127-8

7 January 2021

Subtle Cerebellar Phenotype in Mice Homozygous for a Targeted Deletion of the En-2 Homeobox

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2895%2900127-8

7 January 2021

Elevated blood pressure and craniofacial abnormalities in mice deficient in endothelin-1

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2895%2900127-8

7 January 2021

Alteration of reproductive function but not prenatal sexual development after insertional disruption of the mouse estrogen receptor gene

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2895%2900127-8

7 January 2021

Targeted disruption of the even-skipped gene, evx1, causes early postimplantation lethality of the mouse conceptus

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2895%2900127-8

7 January 2021

Mice with DNA repair gene (ERCC-1) deficiency have elevated levels of p53, liver nuclear abnormalities and die before weaning

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2895%2900127-8

7 January 2021

FcR gamma chain deletion results in pleiotrophic effector cell defects

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2895%2900127-8

7 January 2021

Functional overlap in the src gene family: inactivation of hck and fgr impairs natural immunity

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2895%2900127-8

7 January 2021

Requirement of FGF-4 for postimplantation mouse development

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2895%2900127-8

7 January 2021

Murine FGFR-1 is required for early postimplantation growth and axial organization

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2895%2900127-8

7 January 2021

fgfr-1 is required for embryonic growth and mesodermal patterning during mouse gastrulation

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2895%2900127-8

7 January 2021

Multiple defects and perinatal death in mice deficient in follistatin

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2895%2900127-8

7 January 2021

Pleiotropic effects of a null mutation in the c-fos proto-oncogene

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2895%2900127-8

7 January 2021

Bone and haematopoietic defects in mice lacking c-fos

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2895%2900127-8

7 January 2021

Effect of a null mutation of the c-fos proto-oncogene on sexual behavior of male mice

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2895%2900127-8

7 January 2021

Targeted disruption of the c-fos gene demonstrates c-fos-dependent and -independent pathways for gene expression stimulated by growth factors or oncogenes

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2895%2900127-8

7 January 2021

Normal peripheral T-cell function in c-Fos-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2895%2900127-8

7 January 2021

Behavioral assessment of c-fos mutant mice

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2895%2900127-8

7 January 2021

Mice lacking c-fos have normal hematopoietic stem cells but exhibit altered B-cell differentiation due to an impaired bone marrow environment

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2895%2900127-8

7 January 2021

c-Fos: a key regulator of osteoclast-macrophage lineage determination and bone remodeling

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2895%2900127-8

7 January 2021

A role for Fyn tyrosine kinase in the suckling behaviour of neonatal mice

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2895%2900127-8

7 January 2021

pp59fyn mutant mice display differential signaling in thymocytes and peripheral T cells

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2895%2900127-8

7 January 2021

Initial events of myelination involve Fyn tyrosine kinase signalling

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2895%2900127-8

7 January 2021

Impaired neurite outgrowth of src-minus cerebellar neurons on the cell adhesion molecule L1.

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2895%2900127-8

7 January 2021

Endothelial cell transformation by polyomavirus middle T antigen in mice lacking Src-related kinases.

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2895%2900127-8

7 January 2021

NCAM-dependent neurite outgrowth is inhibited in neurons from Fyn-minus mice

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2895%2900127-8

7 January 2021

Defective T cell receptor signaling in mice lacking the thymic isoform of p59fyn

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2895%2900127-8

7 January 2021

An early haematopoietic defect in mice lacking the transcription factor GATA-2

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2895%2900127-8

7 January 2021

Mice devoid of the glial fibrillary acidic protein develop normally and are susceptible to scrapie prions

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2895%2900127-8

7 January 2021

Lethal thalassemia after insertional disruption of the mouse major adult beta-globin gene

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2895%2900127-8

7 January 2021

Animal model of Gaucher's disease from targeted disruption of the mouse glucocerebrosidase gene

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2895%2900127-8

7 January 2021

Reduced hippocampal long-term potentiation and context-specific deficit in associative learning in mGluR1 mutant mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2895%2900127-8

7 January 2021

Deficient cerebellar long-term depression and impaired motor learning in mGluR1 mutant mice

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2895%2900127-8

7 January 2021

Motor deficit and impairment of synaptic plasticity in mice lacking mGluR1.

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2895%2900127-8

7 January 2021

Targeted disruption of NMDA receptor 1 gene abolishes NMDA response and results in neonatal death

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2895%2900127-8

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2895%2900127-8

7 January 2021

Reduced hippocampal LTP and spatial learning in mice lacking NMDA receptor epsilon 1 subunit

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2895%2900127-8

7 January 2021

Granulocyte/macrophage colony-stimulating factor-deficient mice show no major perturbation of hematopoiesis but develop a characteristic pulmonary pathology

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2895%2900127-8

7 January 2021

Involvement of granulocyte-macrophage colony-stimulating factor in pulmonary homeostasis

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2895%2900127-8

7 January 2021

Cytotoxic lymphocytes require granzyme B for the rapid induction of DNA fragmentation and apoptosis in allogeneic target cells

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2895%2900127-8

7 January 2021

Neuronal pathfinding is abnormal in mice lacking the neuronal growth cone protein GAP-43

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2895%2900127-8

7 January 2021

Mild dyslipidemia in mice following targeted inactivation of the hepatic lipase gene

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2895%2900127-8

7 January 2021

Scatter factor/hepatocyte growth factor is essential for liver development

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2895%2900127-8

7 January 2021

Placental defect and embryonic lethality in mice lacking hepatocyte growth factor/scatter factor

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2895%2900127-8

7 January 2021

The winged-helix transcription factor HNF-3 beta is required for notochord development in the mouse embryo

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2895%2900127-8

7 January 2021

HNF-3 beta is essential for node and notochord formation in mouse development

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2895%2900127-8

7 January 2021

Disruption of the HNF-4 gene, expressed in visceral endoderm, leads to cell death in embryonic ectoderm and impaired gastrulation of mouse embryos

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2895%2900127-8

7 January 2021

Targeted disruption of the Hexa gene results in mice with biochemical and pathologic features of Tay-Sachs disease

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2895%2900127-8

7 January 2021

Hox11 controls the genesis of the spleen

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2895%2900127-8

7 January 2021

Developmental defects of the ear, cranial nerves and hindbrain resulting from targeted disruption of the mouse homeobox gene Hox-1.6

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2895%2900127-8

7 January 2021

Disruption of the Hox-1.6 homeobox gene results in defects in a region corresponding to its rostral domain of expression

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2895%2900127-8

7 January 2021

Local alterations of Krox-20 and Hox gene expression in the hindbrain suggest lack of rhombomeres 4 and 5 in homozygote null Hoxa-1 (Hox-1.6) mutant embryos

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2895%2900127-8

7 January 2021

A homeotic transformation is generated in the rostral branchial region of the head by disruption of Hoxa-2, which acts as a selector gene

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2895%2900127-8

7 January 2021

Hoxa-2 mutant mice exhibit homeotic transformation of skeletal elements derived from cranial neural crest

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2895%2900127-8

7 January 2021

Regionally restricted developmental defects resulting from targeted disruption of the mouse homeobox gene hox-1.5

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2895%2900127-8

7 January 2021

Homeotic transformation of cervical vertebrae in Hoxa-4 mutant mice

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2895%2900127-8

7 January 2021

Specification of axial identity in the mouse: role of the Hoxa-5 (Hox1.3) gene

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2895%2900127-8

7 January 2021

Homeotic transformations and limb defects in Hox A11 mutant mice

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2895%2900127-8

7 January 2021

Genetic interaction between hoxb-5 and hoxb-6 is revealed by nonallelic noncomplementation

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2895%2900127-8

7 January 2021

Homeosis in the mouse induced by a null mutation in the Hox-3.1 gene

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2895%2900127-8

7 January 2021

Axial skeleton homeosis and forelimb malformations in Hoxd-11 mutant mice

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2895%2900127-8

7 January 2021

Disruption of the Hoxd-13 gene induces localized heterochrony leading to mice with neotenic limbs

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2895%2900127-8

7 January 2021

10.1016/S0960-9822(95)00127-8

Identifiers

DOI

1 reference

20 September 2017

1 reference