Helper and suppressor T cell factors (Q40261941)

19 September 2017

title

Helper and suppressor T cell factors (English)

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19 September 2017

2

B Benacerraf

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19 September 2017

R N Germain

1

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19 September 2017

publication date

1 May 1980

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Seminars in Immunopathology

19 September 2017

language of work or name

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19 September 2017

volume

3

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19 September 2017

issue

1

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19 September 2017

page(s)

93-127

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publication type of scholarly work

19 September 2017

review article

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Regulatory mechanisms in cell-mediated immune responses. III. I-region control of suppressor cell interaction with responder cells in mixed lymphocyte reactions

cites work

1 reference

12 December 2020

In vitro studies on H-2-linked unresponsiveness to synthetic polypeptides. III. Production of an antigen-specific T helper cell factor to (T,G)-A--L.

1 reference

12 December 2020

Genetic control of specific immune suppression. II. H-2-linked dominant genetic control of immune suppression by the random copolymer L-glutamic acid50-L-tyrosine50 (GT)

1 reference

12 December 2020

Nonspecific macrophage suppressor factor: its role in the inhibition of contact sensitivity to picryl chloride by specific T suppressor factor

1 reference

12 December 2020

Antigen-specific T cell-mediated suppression. V. H-2-linked genetic control of distinct antigen-specific defects in the production and activity of L-glutamic acid50-L-tyrosine50 suppressor factor

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12 December 2020

Towards a network theory of the immune system.

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12 December 2020

Properties of the antigen-specific suppressive T-cell factor in the regulation of antibody response of the mouse. IV. Special subregion assignment of the gene(s) that codes for the suppressive T-cell factor in the H-2 histocompatibility complex

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12 December 2020

Enrichment of specific suppressor T cells and characterization of their surface markers

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12 December 2020

Immunoregulatory circuits among T cell sets: effect of mode of immunization on determining which Lyl T cell sets will be activated

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12 December 2020

Antigen-specific T-cell factor in cell cooperation. Mapping within the I region of the H-2 complex and ability to cooperate across allogeneic barriers

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12 December 2020

T Cell Control of Antibody Production

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12 December 2020

T cell factor which can replace T cells in vivo

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12 December 2020

Genetic control of immune responses

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12 December 2020

Cellular and genetic control of antibody responses. V. Helper T-cell recognition of H-2 determinants on accessory cells but not B cells

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12 December 2020

Suppressor T cells in tolerance to human gamma-globulin: mediation by a specific soluble factor

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12 December 2020

Antigen-specific suppressive factor produced by a transplantable I-J bearing T-cell hybridoma

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12 December 2020

Cell interactions in the immune response in vitro. 3. Specific collaboration across a cell impermeable membrane

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12 December 2020

The Role of Antigen-Specific T Cell Factors in the Immune Response

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12 December 2020

Immunosuppressive factor(s) specific for L-glutamic acid50-L-tyrosine50 (GT). III. Generation of suppressor T cells by a suppressive extract derived from GT-primed lymphoid cells

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12 December 2020

Immunosuppressive factor(s) specific for L-glutamic acid50-L-tyrosine50 (GT). I. Production, characterization, and lack of H-2 restriction for activity in recipient strain

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12 December 2020

Induction of Specific Helper Cells in vitro

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12 December 2020

The Stimulation of Specific Suppressor T Cells in Genetic Non-Responder Mice by Linear Random Copolymers of L-Amino Acids

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12 December 2020

Antigen-specific T-cell factor in cell cooperation: physical properties and mapping in the left-hand (K) half of H-2

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12 December 2020

Genetic control of immune responses in vitro. V. Stimulation of suppressor T cells in nonresponder mice by the terpolymer L-glutamic acid 60-L-alanine 30-L-tyrosine 10 (GAT).

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12 December 2020

The Hermaphrocyte: A Suppressor-Helper T Cell

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12 December 2020

Two genes in the major histocompatibility complex control immune response

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12 December 2020

Immunoregulatory circuits among T-cell sets. I. T-helper cells induce other T-cell sets to exert feedback inhibition

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12 December 2020

Lymphocytes as Models for the Study of Mammalian Cellular Differentiation

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12 December 2020

The immune response genes of the major histocompatibility complex

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12 December 2020

Regulatory mechanisms in cell-mediated immune responses. VII. Presence of I-C subregion determinants on mixed leukocyte reaction suppressor factor

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12 December 2020

A Cellular Basis for Genetically Controlled Immunologic Unresponsiveness in Mice: Tolerance Induction in T-Cells

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12 December 2020

T Cell-Dependent Suppression of an Anti-Hapten Antibody Response

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12 December 2020

Genetic control of the antibody response in inbred mice. Transfer of response by spleen cells and linkage to the major histocompatibility (H-2) locus

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12 December 2020

Immunosuppressive factor(s) extracted from lymphoid cells of nonresponder mice primed with L-glutamic acid60-L-alanine30-L-tyrosine10 (GAT) II. Cellular source and effect on responder and nonresponder mice

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12 December 2020

Genetic Control of Specific Immune Responses and Immune Suppressions by I-region Genes

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12 December 2020

Interference with the transmission of T cell-derived messages by macrophage membranes

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12 December 2020

Antigen-specific T cell factors: a fine analysis of specificity

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12 December 2020

Idiotypic analysis of antibodies against the terpolymerL-glutamic acid60-L-alanine30-L-tyrosine10 (GAT) IV. Induction of CGAT idiotype following immuniza- tion with various synthetic polymers containing glutamic acid and tyrosine

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12 December 2020

Nature of the T-cell receptor. Both the T-cell receptor and antigen-specific T-cell-derived factors are coded for by V genes but express anti-self idiotypes indirectly determined by major histocompatibility complex genes

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12 December 2020

Idiotypic analysis of anti-GAT antibodies. I. Presence of common idiotypic specificities in both responder and nonresponder mice

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12 December 2020

Immunosuppressive factor(s) extracted from lymphoid cells of nonresponder mice primed with L-glutamic acid60-L-alanine30-L-tyrosine10 (GAT)

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12 December 2020

Antigen-Binding, Idiotypic T-Lymphocyte Receptors

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12 December 2020

Antigen specific T-cell helper factor cross reacts idiotypically with antibodies of the same specificity

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12 December 2020

Antigen-specific thymus cell factors in the genetic control of the immune response to poly-(tyrosyl, glutamyl)-poly-D, L-alanyl--poly-lysyl

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12 December 2020

Properties of the antigen-specific suppressive T-cell factor in the regulation of antibody response of the mouse. III. Dual gene control of the T-cell-mediated suppression of the antibody response

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12 December 2020

Cellular and genetic control of antibody responses in vitro. III. Immune response gene regulation of accessory cell function

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12 December 2020

Suppressor-cell induction in vitro. IV. Target of antigen-specific suppressor factor and its genetic relationships

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12 December 2020

Generation of specific helper cells and suppressor cells in vitro for the IgE and IgG antibody responses

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12 December 2020

Genetic control of immunoregulatory circuits. Genes linked to the Ig locus govern communication between regulatory T-cell sets

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12 December 2020

Mechanisms of regulation of cell-mediated immunity. III. The characterization of azobenzenearsonate-specific suppressor T-cell-derived-suppressor factors

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12 December 2020

Genetic control of immune responses in vitro. I. Development of primary and secondary plaque-forming cell responses to the random terpolymer 1-glutamic acid 60-1-alanine30-1-tyrosine10 (GAT) by mouse spleen cells in vitro

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12 December 2020

Idiotypic analysis of lymphocytes in vitro. I. Specificity and heterogeneity of B and T lymphocytes reactive with anti-idiotypic antibody

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12 December 2020

Regulation of homocytotropic antibody formation in the rat. 8. An antigen-specific T cell factor that regulates anti-hapten homocytotropic antibody response

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12 December 2020

Depression of the T Cell Phenomenon of Contact Sensitivity by T Cells from Unresponsive Mice

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12 December 2020

Characterization of immune response and mixed lymphocyte reactions in selected intra-H-2 recombinant strains

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12 December 2020

Functional and molecular organisation of an antigen-specific suppressor factor from a T-cell hybridoma

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12 December 2020

T-T interactions in the induction of suppressor and helper T cells: analysis of membrane phenotype of precursor and amplifier cells

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12 December 2020

Studies on the chemical basis of the antigenicity of proteins. 5. Synthesis, characterization and immunogenicity of some multichain and linear polypeptides containing tyrosine

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12 December 2020

Antigen-specific T cell-mediated suppression. IV. Role of macrophages in generation of L-glutamic acid60-L-alanine30-L-tyrosine10 (GAT)-specific suppressor T cells in responder mouse strains

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12 December 2020

Regulation of homocytotropic antibody formation in the rat. IX. Further characterization of the antigen-specific inhibitory T cell factor in hapten-specific homocytotropic antibody response

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12 December 2020

Purification of functional, determinant-specific, idiotype-bearing murine T cells

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12 December 2020

Regulatory mechanisms in cell-mediated immune responses. II. A genetically restricted suppressor of mixed lymphocyte reactions released by alloantigen-activated spleen cells

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12 December 2020

Soluble factors in tolerance and contact sensitivity to 2,4-dinitrofluorobenzene in mice. I. Suppression of contact sensitivity by soluble suppressor factor released in vitro by lymph node cell populations containing specific suppressor cells

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12 December 2020

Development and function of subpopulations of thymocytes and T lymphocytes

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12 December 2020

Structure of an antigen-specific suppressor factor produced by a hybrid T-cell line

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12 December 2020

Antigen-specific T cell-mediated suppression. II. In vitro induction by I-J-coded L-glutamic acid50-L-tyrosine50 (GT)-specific T cell suppressor factor (GT-T8F) of suppressor T cells (T82) bearing distinct I-J determinants

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12 December 2020

Role of macrophages in in vitro induction of T-helper cells

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12 December 2020

Specific enrichment of the suppressor T cell bearing I-J determinants: parallel functional and serological characterizations

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12 December 2020

Mechanisms of regulation of cell-mediated immunity. II. Induction and suppression of delayed-type hypersensitivity to azobenzenearsonate-coupled syngeneic cells

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12 December 2020

Major histocompatibility complex restricted cell-mediated immunity

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12 December 2020

Suppressive and Enhancing T-cell Factors as I-region Gene Products: Properties and the Subregion Assignment

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12 December 2020

A new I subregion (I-J) marked by a locus (Ia-4) controlling surface determinants on suppressor T lymphocytes

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12 December 2020

Regulation of the immune response to tumor antigens. III. Characterization of thymic suppressor factor(s) produced by tumor-bearing hosts

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12 December 2020

Antigen specific T cell-mediated suppression. VI. Properties of in vitro generated L-glutamic acid60-L-alanine30-L-tyrosine10 (GAT)-specific T-suppressor factor(s) (GAT-TsF) in responder mouse strains

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12 December 2020

Antigen- and receptor-driven regulatory mechanisms. IV. Idiotype-bearing I-J+ suppressor T cell factors induce second-order suppressor T cells which express anti-idiotypic receptors

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12 December 2020

Properties of antigen-specific suppressive T cell factor in the regulation of antibody response of the mouse. II. In vitro activity and evidence for the I region gene product

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12 December 2020

Properties of Primed Suppressor T Cells and their Products

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12 December 2020

Studies of Structure and Immunosuppression of a Cross-Reactive Idiotype in Strain A Mice

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12 December 2020

Immunosuppressive factor(s) extracted from lymphoid cells of nonresponder mice primed with L-glutamic acid60-L-alanine30-L-tyrosine10 (GAT) III. Immunochemical properties of the GAT-specific suppressive factor

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12 December 2020

Immunologic tolerance to HGG in mice. I. Suppression of the HGG response in normal mice with spleen cells or a spleen cell lysate from tolerant mice

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12 December 2020

Suppressor cell inductionin vitro. I. Kinetics of induction of antigen-specific suppressor cells

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12 December 2020

Antigen-specific T-cell-mediated suppression. I. Induction of L-glutamic acid60-L-alanine30-L-tyrosine10 specific suppressor T cells in vitro requires both antigen-specific T-cell-suppressor factor and antigen

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12 December 2020

Specific suppression of the immune response by a factor obtained from spleen cells of mice tolerant to human gamma-globulin

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12 December 2020

The mechanism of immunological unresponsiveness to picryl chloride and the possible role of antibody mediated depression

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12 December 2020

Immunosuppressive factor(s) specific for L-glutamic acid(50)-L- tyrosine(50) (GT). II. Presence of I-J determinants on the GT-suppressive factor

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12 December 2020

The purification of specific anti-picryl T suppressor factor which depresses the passive transfer of contact sensitivity: affinity chromatography on antigen and Concanavalin A sepharose and specific elution with hapten and alpha-methylmannoside

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12 December 2020

Regulatory mechanisms in cell-mediated immune responses. VI. Interaction of H-2 and non-H-2 genes in elaboration of mixed leukocyte reaction suppressor factor

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12 December 2020

Structural studies on the murine Ia alloantigens. V. Evidence that the structural gene for the I-E/C beta polypeptide is encoded within the I-A subregion

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12 December 2020

In vitro absorption and molecular weight of specific T-cell suppressor factor

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12 December 2020

H-2 restriction of suppressor T-cell induction by hapten-modified lymphoid cells in tolerance to 1-fluoro-2,4-dinitrobenzene contact sensitization

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12 December 2020

Mechanisms of regulation of cell-mediated immunity. IV. Azobenzenearsonate-specific suppressor factor(s) bear cross-reactive idiotypic determinants the expression of which is linked to the heavy-chain allotype linkage group of genes

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12 December 2020

Genetic control of specific immune suppression. III. Mapping of H-2 complex complementing genes controlling immune suppression by the random copolymer L-glutamic acid50-L-tyrosine50 (GT)

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12 December 2020

The role of H-2-linked genes in helper T-cell function. III. Expression of immune response genes for trinitrophenyl conjugates of poly-L(Tyr, Glu)-poly-D,L-Ala--poly-L-Lys in B cells and macrophages

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12 December 2020

Two distinct types of helper T cells involved in the secondary antibody response: independent and synergistic effects of Ia- and Ia+ helper T cells

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12 December 2020

Immunoregulatory circuits among T-cell sets. Identification of a subpopulation of T-helper cells that induces feedback inhibition

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12 December 2020

Immunosuppressive factors from lymphoid cells of nonresponder mice primed with L-glutamic acid60-L-alanine30-L-tyrosine10. IV. Lack of strain restrictions among allogeneic, nonresponder donors and recipients

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12 December 2020

Suppressor cell induction in vitro. III. Antigen-specific suppression by supernatants of suppressor cells

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12 December 2020

Soluble factors in tolerance and contact sensitivity to DNFB in mice. II. Genetic requirements for suppression of contact sensitivity by soluble suppressor factor

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12 December 2020

Immune response (Ir) genes expressed at macrophage–B lymphocyte interactions

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12 December 2020

Suppressor cell inductionin vitro. II. Cellular requirements of suppressor cell induction

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12 December 2020

The I-J subregion codes for determinants on suppressor factor(s) which limit the contact sensitivity response to picryl chloride

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12 December 2020

Regulation of the immune response to tumor antigen. IV. Tumor antigen-specific suppressor factor(s) bear I-J determinants and induce suppressor T cells in vivo

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12 December 2020

T-cell lines producing antigen-specific suppressor factor

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12 December 2020

Shared idiotypic determinants on B and T lymphocytes reactive against the same antigenic determinants. V. Biochemical and serological characteristics of naturally occurring, soluble antigen-binding T-lymphocyte-derived molecules

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12 December 2020

Specific suppressive factors produced by hybridomas derived from the fusion of enriched suppressor T cells and a T lymphoma cell line

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12 December 2020

Production of an H–2-related suppressor factor by a hybrid T-cell line

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12 December 2020

Properties of antigen-specific suppressive T-cell factor in the regulation of antibody response of the mouse. I. In vivo activity and immunochemical characterization

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12 December 2020

Idiotypic analysis of antibodies to poly(Glu60Ala30Tyr10): interstrain and interspecies idiotypic crossreactions

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12 December 2020

Isolated hapten-binding receptors of sensitized lymphocytes I. Receptors from nylon wool-enriched mouse T lymphocyte lack serological markers of immunoglobulin constant domain but express heavy chain variable portions

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12 December 2020

Antigen-specific T-cell factors in the genetic control of the immune response to poly(Tyr,Glu)-polyDLAla--polyLys. Evidence for T- and B-cell defects in SJL mice

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12 December 2020

Immunosuppressive factor(s) specific for L-glutamic acid50-L-tyosine50. IV. In vitro activity and immunochemical properties

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12 December 2020

Regulatory mechanisms in cell-mediated immune responses. I. Regulation of mixed lymphocyte reactions by alloantigen-activated thymus-derived lymphocytes

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12 December 2020

Removal of specific cooperative T cell factor by anti-H-2 but not by anti-Ig sera

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12 December 2020

A mendelian idiotype is demonstrable in the heteroclitic anti-NP antibodies of the mouse

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12 December 2020

Complementation of immune response genes for (T,G)-A-L

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12 December 2020

Shared idiotypic determinants on antibodies and T-cell-derived suppressor factor specific for the random terpolymer L-glutamic acid60-L-alanine30-L-tyrosine10

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12 December 2020

An antigen-specific I region gene product that augments the antibody response

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12 December 2020

Idiotypic analysis of anti-GAT antibodies. III. Determinant specificity and immunoglobulin class distribution of CGAT idiotype

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12 December 2020

In vitro studies on H-2 linked unresponsiveness to synthetic polypeptide antigens. II. Induction of suppressor cells in both responsive and unresponsive mice to (T,G)-A-L and GAT;

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12 December 2020

Genetic Control of Specific Immune Responses

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12 December 2020

Soluble factors in tolerance and contact sensitivity to 2,4-dinitrofluorobenzene in mice. III. Histocompatibility antigens associated with the hapten dinitrophenol serve as target molecules on 2,4-dinitrofluorobenzene-immune T cells for soluble supp

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12 December 2020

Hapten-specific T-cell responses to 4-hydroxy-3-nitrophenyl acetyl. I. Genetic control of delayed-type hypersensitivity by VH and I-A-region genes

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12 December 2020

Serological analysis of antigen-specific helper factors specific for poly-L(Tyr, Glu)-poly-DLAla–poly-LLys [(T, G)-A–L] andLGlu60-LAla30-LTyr10 (GAT)

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12 December 2020

Expression and Function of Idiotypes on Lymphocytes

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12 December 2020

Immunosuppressor T cells in tumor bearing host

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12 December 2020

Genetic control of the immune response to the terpolymer L-glutamic acid60-L-aIanine30-L-tyrosme10 (GAT): II. Characterization of a cross-reactive idiotype associated with anti-GAT antibodies from responder and nonresponder mice

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12 December 2020

Antigen Specific T Cell Factors in the Genetic Control of the Immune Response to Poly(Tyr, Glu)-Poly(Pro)—Poly(Lys)

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12 December 2020

Regulatory mechanisms in cell-mediated immune responses. IV. Expression of a receptor for mixed lymphocyte reaction suppressor factor on activated T lymphocytes

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12 December 2020

Regulation of the immune response to tumor antigens. II. The nature of immunosuppressor cells in tumor-bearing hosts

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12 December 2020

Suppressor cell induction in vitro. VI. Production of suppressor factors to synthetic polypeptides GAT and (T,G)-A--L from cells of responder and nonresponder mice

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12 December 2020

Selective roles of thymus-derived lymphocytes in the antibody response. II. Preferential suppression of high-affinity antibody-forming cells by carrier-primed suppressor T cells

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12 December 2020

Genetic control of specific immune suppression. I. Experimental conditions for the stimulation of suppressor cells by the copolymer L-glutamic acid50-L-tyrosine50 (GT) in nonresponder BALB/c mice

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12 December 2020

Regualtion of the immune response to tumor antigens. I. Immunosuppressor cells in tumor-bearing hosts

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12 December 2020

Control of t-lymphocyte and B-lymphocyte activation by two complementing Ir-GLphi immune response genes

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12 December 2020

Identifiers

DOI

10.1007/BF00199927

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19 September 2017

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