Integration of Human Papillomavirus Genomes in Head and Neck Cancer: Is It Time to Consider a Paradigm Shift? (Q40096630)

17 September 2017

1 reference

19 January 2021

Integration of Human Papillomavirus Genomes in Head and Neck Cancer: Is It Time to Consider a Paradigm Shift? (English)

1 reference

Papillomavirus infections

17 September 2017

1 reference

7 August 2019

1 reference

19 January 2021

head and neck neoplasms

1 reference

19 January 2021

human papillomavirus 16

1 reference

19 January 2021

1 reference

1 reference

1 reference

1 reference

head and neck carcinoma

1 reference

Iain M Morgan

1

1 reference

17 September 2017

Laurence J DiNardo

series ordinal

2

1 reference

17 September 2017

Brad Windle

series ordinal

3

1 reference

17 September 2017

language of work or name

1 reference

3 August 2017

8 references

17 September 2017

23 March 2019

3 April 2019

7 August 2019

21 October 2019

3 November 2019

16 December 2020

19 January 2021

8 references

17 September 2017

23 March 2019

3 April 2019

7 August 2019

21 October 2019

3 November 2019

16 December 2020

19 January 2021

9

1 reference

17 September 2017

8

1 reference

Creative Commons Attribution

17 September 2017

7 references

23 March 2019

3 April 2019

7 August 2019

21 October 2019

3 November 2019

16 December 2020

19 January 2021

0 references

on focus list of Wikimedia project

ScienceSource

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cites work

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22 September 2017

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22 September 2017

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Characterization of HPV and host genome interactions in primary head and neck cancers

22 September 2017

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22 September 2017

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22 September 2017

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22 September 2017

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22 September 2017

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22 September 2017

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22 September 2017

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22 September 2017

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22 September 2017

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22 September 2017

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22 September 2017

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22 September 2017

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22 September 2017

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In vitro progression of human papillomavirus 16 episome-associated cervical neoplasia displays fundamental similarities to integrant-associated carcinogenesis

22 September 2017

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Human papillomaviruses activate the ATM DNA damage pathway for viral genome amplification upon differentiation

22 September 2017

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The dynamic DNA methylomes of double-stranded DNA viruses associated with human cancer

22 September 2017

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22 September 2017

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22 September 2017

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22 September 2017

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22 September 2017

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Genomic instability of the host cell induced by the human papillomavirus replication machinery

22 September 2017

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TopBP1 regulates human papillomavirus type 16 E2 interaction with chromatin

22 September 2017

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ChlR1 is required for loading papillomavirus E2 onto mitotic chromosomes and viral genome maintenance

22 September 2017

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E2 proteins from high- and low-risk human papillomavirus types differ in their ability to bind p53 and induce apoptotic cell death

22 September 2017

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22 September 2017

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Human papillomaviruses: basic mechanisms of pathogenesis and oncogenicity

22 September 2017

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Human papillomavirus-associated head and neck cancer is a distinct epidemiologic, clinical, and molecular entity

22 September 2017

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Conserved methylation patterns of human papillomavirus type 16 DNA in asymptomatic infection and cervical neoplasia

22 September 2017

1 reference

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Interaction of the bovine papillomavirus E2 protein with Brd4 tethers the viral DNA to host mitotic chromosomes

22 September 2017

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Recruitment of replication protein A by the papillomavirus E1 protein and modulation by single-stranded DNA

22 September 2017

1 reference

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A subset of head and neck squamous cell carcinomas exhibits integration of HPV 16/18 DNA and overexpression of p16INK4A and p53 in the absence of mutations in p53 exons 5–8

22 September 2017

1 reference

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CpG methylation of human papillomavirus type 16 DNA in cervical cancer cell lines and in clinical specimens: genomic hypomethylation correlates with carcinogenic progression

22 September 2017

1 reference

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Human papillomavirus type 16 E2 protein has no effect on transcription from episomal viral DNA.

22 September 2017

1 reference

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Endogenous human papillomavirus E6 and E7 proteins differentially regulate proliferation, senescence, and apoptosis in HeLa cervical carcinoma cells

22 September 2017

1 reference

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A Functional interaction between the human papillomavirus 16 transcription/replication factor E2 and the DNA damage response protein TopBP1

22 September 2017

1 reference

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Human papillomavirus-associated head and neck squamous cell carcinoma: mounting evidence for an etiologic role for human papillomavirus in a subset of head and neck cancers

22 September 2017

1 reference

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Evidence for a causal association between human papillomavirus and a subset of head and neck cancers

22 September 2017

1 reference

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Analysis by multiplex PCR of the physical status of human papillomavirus type 16 DNA in cervical cancers

22 September 2017

1 reference

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A C-terminal helicase domain of the human papillomavirus E1 protein binds E2 and the DNA polymerase alpha-primase p68 subunit.

22 September 2017

1 reference

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Different mechanisms contribute to the E2-mediated transcriptional repression of human papillomavirus type 18 viral oncogenes

22 September 2017

1 reference

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Characterization of the human papillomavirus E2 protein: evidence of trans-activation and trans-repression in cervical keratinocytes.

22 September 2017

1 reference

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Integration of human papillomavirus type 16 into the human genome correlates with a selective growth advantage of cells

22 September 2017

1 reference

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Coexistence of episomal and integrated HPV16 DNA in squamous cell carcinoma of the cervix

22 September 2017

1 reference

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Changes in the physical state and expression of human papillomavirus type 16 in the progression of cervical intraepithelial neoplasia lesions analysed by PCR.

22 September 2017

1 reference

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Cellular factors required for papillomavirus DNA replication.

22 September 2017

1 reference

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Papillomavirus sequences integrate near cellular oncogenes in some cervical carcinomas

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5580465

Structural and transcriptional analysis of human papillomavirus type 16 sequences in cervical carcinoma cell lines

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5580465

Mutational analysis of cis elements involved in E2 modulation of human papillomavirus type 16 P97 and type 18 P105 promoters

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5580465

Analysis of integrated human papillomavirus type 16 DNA in cervical cancers: amplification of viral sequences together with cellular flanking sequences.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5580465

Analysis of the physical state of different human papillomavirus DNAs in intraepithelial and invasive cervical neoplasm

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5580465

Integration of papillomavirus DNA near myc genes in genital carcinomas and its consequences for proto-oncogene expression.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5580465

In situ human papillomavirus (HPV) genotyping of cervical intraepithelial neoplasia in South African and British patients: evidence for putative HPV integration in vivo

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5580465

Integration of human papillomavirus types 16 and 18 in cervical adenocarcinoma

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5580465

Disruption of either the E1 or the E2 regulatory gene of human papillomavirus type 16 increases viral immortalization capacity

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5580465

Human papillomavirus integration pattern and demographic, clinical, and survival characteristics of patients with oropharyngeal squamous cell carcinoma

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5580465

Studies on human papillomavirus (HPV) 16 E2, E5 and E7 mRNA in HPV-positive tonsillar and base of tongue cancer in relation to clinical outcome and immunological parameters

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5580465

Analysis of the integration of human papillomaviruses in head and neck tumours in relation to patients' prognosis

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5580465

Assessment of the HPV DNA methylation status in cervical lesions

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5580465

A high and increasing HPV prevalence in tonsillar cancers in Eastern Denmark, 2000-2010: the largest registry-based study to date

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5580465

Papillomavirus E1 protein binds to and stimulates human topoisomerase I

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5580465

Presence of episomal and integrated human papillomavirus DNA sequences in cervical carcinoma

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5580465

Integration and transcription of human papillomavirus type 16 and 18 sequences in cell lines derived from cervical carcinomas

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5580465

Chromosomal integration sites of human papillomavirus DNA in three cervical cancer cell lines mapped by in situ hybridization

17 June 2018

1 reference

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Characterization of normal human exocervical epithelial cells immortalized in vitro by papillomavirus types 16 and 18 DNA.

17 June 2018

1 reference

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Validation of the ICON-S staging for HPV-associated oropharyngeal carcinoma using a pre-defined treatment policy.

17 June 2018

1 reference

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Viral load, physical status, and E6/E7 mRNA expression of human papillomavirus in head and neck squamous cell carcinoma

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5580465

p16 expression in oropharyngeal cancer: its impact on staging and prognosis compared with the conventional clinical staging parameters

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5580465

HPV integration begins in the tonsillar crypt and leads to the alteration of p16, EGFR and c-myc during tumor formation.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5580465

Interferon-beta treatment of cervical keratinocytes naturally infected with human papillomavirus 16 episomes promotes rapid reduction in episome numbers and emergence of latent integrants.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5580465

CpG methylation of HPV 16 LCR at E2 binding site proximal to P97 is associated with cervical cancer in presence of intact E2.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5580465

Tissue distribution of human papillomavirus 16 DNA integration in patients with tonsillar carcinoma.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5580465

Physical status and expression of HPV genes in cervical cancers.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5580465

Association of human papillomavirus type 16 integration in the E2 gene with poor disease-free survival from cervical cancer.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5580465

An oral keratinocyte life cycle model identifies novel host genome regulation by human papillomavirus 16 relevant to HPV positive head and neck cancer

20 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.3390%2FV9080208

Induced senescence in HeLa cervical carcinoma cells containing elevated telomerase activity and extended telomeres

21 January 2018

1 reference

12 December 2020

HPV DNA detection by in situ hybridization with catalyzed signal amplification on thin-layer cervical smears

1 reference

12 December 2020

Association of viral load with HPV16 positive cervical cancer pathogenesis: causal relevance in isolates harboring intact viral E2 gene

1 reference

12 December 2020

The physical state of human papillomavirus 16 DNA in cervical carcinoma and cervical intraepithelial neoplasia

1 reference

12 December 2020

Integration of human papillomavirus type 16 into cellular DNA of cervical carcinoma: preferential deletion of the E2 gene and invariable retention of the long control region and the E6/E7 open reading frames

1 reference

12 December 2020

Physical state and biological activity of human papillomavirus genomes in precancerous lesions of the female genital tract

1 reference

12 December 2020

The physical state of human papillomavirus type 16 DNA in benign and malignant genital tumours

1 reference

12 December 2020

Activation of the endogenous p53 growth inhibitory pathway in HeLa cervical carcinoma cells by expression of the bovine papillomavirus E2 gene

1 reference

12 December 2020

Identifiers

DOI

10.3390/V9080208

1 reference

release_ytbfdzeaibbcjasr32oicva62q

17 September 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/ytbfdzeaibbcjasr32oicva62q

24 November 2022

mapped directly with Wikidata item

1 reference

17 September 2017

1 reference