Neurofibromatosis 2 tumor suppressor, the gene induced by valproic acid, mediates neurite outgrowth through interaction with paxillin (Q39981215)

16 September 2017

Neurofibromatosis 2 tumor suppressor, the gene induced by valproic acid, mediates neurite outgrowth through interaction with paxillin (English)

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neurofibromatosis type II

16 September 2017

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Junji Yamauchi

1

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16 September 2017

Yuki Miyamoto

2

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16 September 2017

Shinji Kusakawa

3

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16 September 2017

Tomohiro Torii

4

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16 September 2017

Reiko Mizutani

5

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16 September 2017

Atsushi Sanbe

6

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16 September 2017

Hideki Nakajima

7

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16 September 2017

Nobutaka Kiyokawa

8

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16 September 2017

Akito Tanoue

9

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16 September 2017

language of work or name

English

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publication date

8 April 2008

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Experimental Cell Research

16 September 2017

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16 September 2017

314

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16 September 2017

2279-2288

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16 September 2017

11-12

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Alteration in a new gene encoding a putative membrane-organizing protein causes neuro-fibromatosis type 2

16 September 2017

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.03.019

A novel moesin-, ezrin-, radixin-like gene is a candidate for the neurofibromatosis 2 tumor suppressor.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.03.019

Neurofibromatosis 2 tumour suppressor schwannomin interacts with betaII-spectrin

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.03.019

Paxillin binds schwannomin and regulates its density-dependent localization and effect on cell morphology

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.03.019

Protein 4.1 tumor suppressors: getting a FERM grip on growth regulation

7 January 2021

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Mechanisms and roles of axon-Schwann cell interactions.

7 January 2021

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Paxillin: adapting to change

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.03.019

MAP kinases and cell migration

7 January 2021

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The cellular neurobiology of depression

7 January 2021

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Finding the Intracellular Signaling Pathways Affected by Mood Disorder Treatments

7 January 2021

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Gadd45a, the gene induced by the mood stabilizer valproic acid, regulates neurite outgrowth through JNK and the substrate paxillin in N1E-115 neuroblastoma cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.03.019

Molecular dissection of the Rho-associated protein kinase (p160ROCK)-regulated neurite remodeling in neuroblastoma N1E-115 cells

7 January 2021

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JNK phosphorylation of paxillin, acting through the Rac1 and Cdc42 signaling cascade, mediates neurite extension in N1E-115 cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.03.019

Phosphorylation of the NF2 tumor suppressor in Schwann cells is mediated by Cdc42-Pak and requires paxillin binding.

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.03.019

Paxillin isoforms in mouse. Lack of the gamma isoform and developmentally specific beta isoform expression.

7 January 2021

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Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor

7 January 2021

1 reference

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The neurotrophin-3 receptor TrkC directly phosphorylates and activates the nucleotide exchange factor Dbs to enhance Schwann cell migration

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.03.019

Expression of protein 4.1G in Schwann cells of the peripheral nervous system.

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.03.019

Integrin-linked kinase (ILK) binding to paxillin LD1 motif regulates ILK localization to focal adhesions

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.03.019

The role of focal adhesion kinase binding in the regulation of tyrosine phosphorylation of paxillin

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.03.019

Paxillin localizes to the lymphocyte microtubule organizing center and associates with the microtubule cytoskeleton

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.03.019

Intact LIM 3 and LIM 4 domains of paxillin are required for the association to a novel polyproline region (Pro 2) of protein-tyrosine phosphatase-PEST

7 January 2021

1 reference

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GEF means go: turning on RHO GTPases with guanine nucleotide-exchange factors

7 January 2021

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The Nf2 tumor suppressor, merlin, functions in Rac-dependent signaling.

7 January 2021

1 reference

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Merlin, the Product of the Nf2 Tumor Suppressor Gene, Is an Inhibitor of the p21-Activated Kinase, Pak1

7 January 2021

1 reference

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Identification and characterization of putative tumor suppressor NGB, a GTP-binding protein that interacts with the neurofibromatosis 2 protein

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.03.019

Paxillin phosphorylation sites mapped by mass spectrometry

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.03.019

Phosphorylation of paxillin by p38MAPK is involved in the neurite extension of PC-12 cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.03.019

Cdk5 regulates differentiation of oligodendrocyte precursor cells through the direct phosphorylation of paxillin

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.03.019

Valproic acid defines a novel class of HDAC inhibitors inducing differentiation of transformed cells

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.03.019

Histone deacetylase is a direct target of valproic acid, a potent anticonvulsant, mood stabilizer, and teratogen

7 January 2021

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The mood-stabilizing agent valproate inhibits the activity of glycogen synthase kinase-3.

7 January 2021

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Regulation of Akt and glycogen synthase kinase-3 beta phosphorylation by sodium valproate and lithium

7 January 2021

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Role of NF2 haploinsufficiency in NF2-associated polyneuropathy

7 January 2021

1 reference

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RhoG activates Rac1 by direct interaction with the Dock180-binding protein Elmo

7 January 2021

1 reference

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Cloning of a novel mitogen-activated protein kinase kinase kinase, MEKK4, that selectively regulates the c-Jun amino terminal kinase pathway

7 January 2021

1 reference

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10.1016/J.YEXCR.2008.03.019

7 January 2021

Identifiers

DOI

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16 September 2017

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