Eukaryotic translation initiation factors and cancer (Q39400409)

11 September 2017

Eukaryotic translation initiation factors and cancer (English)

1 reference

11 September 2017

Muhammad Umar Ali

1

1 reference

11 September 2017

Muhammad Saif Ur Rahman

series ordinal

2

1 reference

11 September 2017

Zhenyu Jia

series ordinal

3

1 reference

11 September 2017

Cao Jiang

series ordinal

4

1 reference

11 September 2017

1 June 2017

1 reference

11 September 2017

1 reference

11 September 2017

39

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11 September 2017

1010428317709805

1 reference

11 September 2017

6

1 reference

Genome-wide analysis in vivo of translation with nucleotide resolution using ribosome profiling

11 September 2017

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

A mechanistic overview of translation initiation in eukaryotes

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

The mechanism of eukaryotic translation initiation: new insights and challenges

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Eukaryotic translation initiation factors in cancer development and progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Human eukaryotic initiation factor 2 (eIF2)-GTP-Met-tRNAi ternary complex and eIF3 stabilize the 43 S preinitiation complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

A multifactor complex of eukaryotic initiation factors, eIF1, eIF2, eIF3, eIF5, and initiator tRNA(Met) is an important translation initiation intermediate in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Interaction between eukaryotic initiation factors 1A and 5B is required for efficient ribosomal subunit joining.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

eIF2 interactions with initiator tRNA and eIF2B are regulated by post-translational modifications and conformational dynamics

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Crystal structure of eukaryotic translation initiation factor 2B

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Human eukaryotic initiation factor 4G (eIF4G) protein binds to eIF3c, -d, and -e to promote mRNA recruitment to the ribosome

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Translation initiation factor eIF4G-1 binds to eIF3 through the eIF3e subunit

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Interactions of eukaryotic translation initiation factor 3 (eIF3) subunit NIP1/c with eIF1 and eIF5 promote preinitiation complex assembly and regulate start codon selection

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Eukaryotic translation initiation factor 4G (eIF4G) coordinates interactions with eIF4A, eIF4B, and eIF4E in binding and translation of the barley yellow dwarf virus 3' cap-independent translation element (BTE).

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Molecular mechanisms of translation initiation in eukaryotes

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Structure of the eukaryotic translation initiation factor eIF4E in complex with 4EGI-1 reveals an allosteric mechanism for dissociating eIF4G

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Cap-dependent eukaryotic initiation factor-mRNA interactions probed by cross-linking

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Inhibition of Mitogen-activated Protein Kinase (MAPK)-interacting Kinase (MNK) Preferentially Affects Translation of mRNAs Containing Both a 5'-Terminal Cap and Hairpin

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

The eukaryotic initiation factor eIF4H facilitates loop-binding, repetitive RNA unwinding by the eIF4A DEAD-box helicase

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

eIF2B promotes eIF5 dissociation from eIF2*GDP to facilitate guanine nucleotide exchange for translation initiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

An eIF5/eIF2 complex antagonizes guanine nucleotide exchange by eIF2B during translation initiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Crystal structure of the eukaryotic 60S ribosomal subunit in complex with initiation factor 6

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

5' UTR m(6)A Promotes Cap-Independent Translation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Translation initiation on mRNAs bound by nuclear cap-binding protein complex CBP80/20 requires interaction between CBP80/20-dependent translation initiation factor and eukaryotic translation initiation factor 3g.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

3' end mRNA processing: molecular mechanisms and implications for health and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

The mechanism of eukaryotic translation initiation and principles of its regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

The eukaryotic translation initiation factors eIF1 and eIF1A induce an open conformation of the 40S ribosome

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Coupling 40S ribosome recruitment to modification of a cap-binding initiation factor by eIF3 subunit e.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Regulation of translation initiation in eukaryotes: mechanisms and biological targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Molecular mechanisms of mTOR-mediated translational control

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Decreased expression of EIF4A1 after preoperative brachytherapy predicts better tumor-specific survival in cervical cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Eukaryotic translation initiation factor 4E (eIF4E) expression is associated with breast cancer tumor phenotype and predicts survival after anthracycline chemotherapy treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Phosphoproteomic analysis of signaling pathways in head and neck squamous cell carcinoma patient samples

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Quantitative studies of mRNA recruitment to the eukaryotic ribosome

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

The interaction between eukaryotic initiation factor 1A and eIF5 retains eIF1 within scanning preinitiation complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Principles of start codon recognition in eukaryotic translation initiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

DHX29 reduces leaky scanning through an upstream AUG codon regardless of its nucleotide context

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

eIF1A augments Ago2-mediated Dicer-independent miRNA biogenesis and RNA interference.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Autoantibodies to tumor-associated antigens combined with abnormal alpha-fetoprotein enhance immunodiagnosis of hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

The translation initiation factor, hu-Sui1 may be a target of hepatitis B X antigen in hepatocarcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Exome sequencing identifies recurrent somatic mutations in EIF1AX and SF3B1 in uveal melanoma with disomy 3

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Characterization of the mutational landscape of anaplastic thyroid cancer via whole-exome sequencing

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Integrated genomic characterization of papillary thyroid carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

SF3B1 and EIF1AX mutations occur in primary leptomeningeal melanocytic neoplasms; yet another similarity to uveal melanomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Eukaryotic initiation factor 2 phosphorylation and translational control in metabolism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Perk is essential for translational regulation and cell survival during the unfolded protein response

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Separate domains in GCN1 for binding protein kinase GCN2 and ribosomes are required for GCN2 activation in amino acid-starved cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Phosphorylation of serine 51 in initiation factor 2 alpha (eIF2 alpha) promotes complex formation between eIF2 alpha(P) and eIF2B and causes inhibition in the guanine nucleotide exchange activity of eIF2B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

The eIF2alpha kinases inhibit vesicular stomatitis virus replication independently of eIF2alpha phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

The G1-S checkpoint in fission yeast is not a general DNA damage checkpoint

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

A novel checkpoint mechanism regulating the G1/S transition

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Ultraviolet radiation triggers the ribotoxic stress response in mammalian cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Crosslinking of ribosomal proteins to RNA in maize ribosomes by UV-B and its effects on translation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Activation of GCN2 in UV-irradiated cells inhibits translation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

A UV-responsive internal ribosome entry site enhances serine hydroxymethyltransferase 1 expression for DNA damage repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Defects in translational regulation mediated by the alpha subunit of eukaryotic initiation factor 2 inhibit antiviral activity and facilitate the malignant transformation of human fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Roles of the translation initiation factor eIF2α serine 51 phosphorylation in cancer formation and treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

The role of PKR/eIF2α signaling pathway in prognosis of non-small cell lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Eukaryotic initiation factors (eIF) 2alpha and 4E expression, localization, and phosphorylation in brain tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

FUS-DDIT3 prevents the development of adipocytic precursors in liposarcoma by repressing PPARgamma and C/EBPalpha and activating eIF4E.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

High physiological levels of LMP1 result in phosphorylation of eIF2 alpha in Epstein-Barr virus-infected cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Expression of the translation initiation factors eIF-4E and eIF-2* is frequently increased in neoplastic cells of Hodgkin lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Role of eIF3a in regulating cell cycle progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

eIF3: a versatile scaffold for translation initiation complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

'Ribozoomin'--translation initiation from the perspective of the ribosome-bound eukaryotic initiation factors (eIFs)

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

The j-subunit of human translation initiation factor eIF3 is required for the stable binding of eIF3 and its subcomplexes to 40 S ribosomal subunits in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Structure of the mammalian ribosomal 43S preinitiation complex bound to the scanning factor DHX29

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

The human translation initiation multi-factor complex promotes methionyl-tRNAi binding to the 40S ribosomal subunit

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Structure and interactions of the translation initiation factor eIF1

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Eucaryotic initiation factor 4B controls eIF3-mediated ribosomal entry of viral reinitiation factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Ribosomal position and contacts of mRNA in eukaryotic translation initiation complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Expression of p150 in cervical neoplasia and its potential value in predicting survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Identification of a 170-kDa protein over-expressed in lung cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Frequent overexpression of the genes FXR1, CLAPM1 and EIF4G located on amplicon 3q26-27 in squamous cell carcinoma of the lung

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Eukaryotic translation initiation factor 3B accelerates the progression of esophageal squamous cell carcinoma by activating β-catenin signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Molecular interaction between human tumor marker protein p150, the largest subunit of eIF3, and intermediate filament protein K7

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Translation initiation factor eIF3b expression in human cancer and its role in tumor growth and lung colonization

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Schwannomin inhibits tumorigenesis through direct interaction with the eukaryotic initiation factor subunit c (eIF3c)

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Eukaryotic initiation factor 3 p110 mRNA is overexpressed in testicular seminomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

A gene expression signature of acquired chemoresistance to cisplatin and fluorouracil combination chemotherapy in gastric cancer patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Int6 expression can predict survival in early-stage non-small cell lung cancer patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Decreased expression of eukaryotic initiation factor 3f deregulates translation and apoptosis in tumor cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Loss of the eukaryotic initiation factor 3f in pancreatic cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Loss of the eukaryotic initiation factor 3f in melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Amplification and overexpression of p40 subunit of eukaryotic translation initiation factor 3 in breast and prostate cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

MYC and EIF3H Coamplification significantly improve response and survival of non-small cell lung cancer patients (NSCLC) treated with gefitinib

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

PTK2 and EIF3S3 genes may be amplification targets at 8q23-q24 and are associated with large hepatocellular carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Amplification of EIF3S3 gene is associated with advanced stage in prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

A genome-wide association study identifies colorectal cancer susceptibility loci on chromosomes 10p14 and 8q23.3

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Allogenic antibody-mediated identification of head and neck cancer antigens

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Expression of co-factors (SMRT and Trip-1) for retinoic acid receptors in human neuroectodermal cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

eIF3m expression influences the regulation of tumorigenesis-related genes in human colon cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Eukaryotic translation initiation factors and regulators

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

The DEAD-box helicase eIF4A: paradigm or the odd one out?

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

From unwinding to clamping - the DEAD box RNA helicase family

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Interactions between eIF4AI and its accessory factors eIF4B and eIF4H

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Crystal structure of the eIF4A-PDCD4 complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

eIF4B, eIF4G and RNA regulate eIF4A activity in translation initiation by modulating the eIF4A conformational cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Targeting the eIF4F translation initiation complex: a critical nexus for cancer development

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Translation initiation complex eIF4F is a therapeutic target for dual mTOR kinase inhibitors in non-Hodgkin lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

eIF4B controls survival and proliferation and is regulated by proto-oncogenic signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Interferon-dependent engagement of eukaryotic initiation factor 4B via S6 kinase (S6K)- and ribosomal protein S6K-mediated signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Decreased expression of miR216a contributes to non-small-cell lung cancer progression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Control of cell survival and proliferation by mammalian eukaryotic initiation factor 4B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

The translation factor eIF-4E promotes tumor formation and cooperates with c-Myc in lymphomagenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

The oncogene eIF4E: using biochemical insights to target cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

eIF4E-mediated translational control of cancer incidence.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Targeting the translation machinery in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Glycogen synthase kinase-3β positively regulates protein synthesis and cell proliferation through the regulation of translation initiation factor 4E-binding protein 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Casein kinase 1ε promotes cell proliferation by regulating mRNA translation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

The Eukaryotic Translation Initiation Factor 4E (eIF4E) as a Therapeutic Target for Cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

eIF4E activation is commonly elevated in advanced human prostate cancers and significantly related to reduced patient survival.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Non-Smad pathways in TGF-beta signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Combined analysis of eIF4E and 4E-binding protein expression predicts breast cancer survival and estimates eIF4E activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

4E-binding protein 1, a cell signaling hallmark in breast cancer that correlates with pathologic grade and prognosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Activation of the Akt/mammalian target of rapamycin/4E-BP1 pathway by ErbB2 overexpression predicts tumor progression in breast cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Activation of mammalian target of rapamycin signaling pathway contributes to tumor cell survival in anaplastic lymphoma kinase-positive anaplastic large cell lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Design, synthesis and evaluation of analogs of initiation factor 4E (eIF4E) cap-binding antagonist Bn7-GMP

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

eIF4F suppression in breast cancer affects maintenance and progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Cell-specific expression of artificial microRNAs targeting essential genes exhibit potent antitumor effect on hepatocellular carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Ribosome loading onto the mRNA cap is driven by conformational coupling between eIF4G and eIF4E

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Tumor suppression by small molecule inhibitors of translation initiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Modulation of the helicase activity of eIF4A by eIF4B, eIF4H, and eIF4F.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Duplex unwinding and ATPase activities of the DEAD-box helicase eIF4A are coupled by eIF4G and eIF4B

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Topology and regulation of the human eIF4A/4G/4H helicase complex in translation initiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Translation initiation factor eIF-4A1 mRNA is consistently overexpressed in human melanoma cellsin vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Pharmacological targeting of mammalian target of rapamycin inhibits ovarian granulosa cell tumor growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

A role for eukaryotic initiation factor 4B overexpression in the pathogenesis of diffuse large B-cell lymphoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

eIF4B phosphorylation by pim kinases plays a critical role in cellular transformation by Abl oncogenes

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Eukaryotic initiation factor-4E in superficial and muscle invasive bladder cancer and its correlation with vascular endothelial growth factor expression and tumour progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

eIF-4E expression is associated with histopathologic grades in cervical neoplasia

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Detection of eukaryotic translation initiation factor 4E and its clinical significance in hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

MDM2 is overexpressed and regulated by the eukaryotic translation initiation factor 4E (eIF4E) in human squamous cell carcinoma of esophagus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Expression of eukaryotic initiation factor 4E in gastric adenocarcinoma and its association with clinical outcome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Significance of eIF4E expression in skin squamous cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Phosphorylated eukaryotic translation initiation factor 4 (eIF4E) is elevated in human cancer tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Overexpression of phospho-eIF4E is associated with survival through AKT pathway in non-small cell lung cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Dissecting eIF4E action in tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

eIF4E phosphorylation promotes tumorigenesis and is associated with prostate cancer progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Essential role for eIF4GI overexpression in the pathogenesis of inflammatory breast cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Overexpression of the eukaryotic translation initiation factor 4G (eIF4G-1) in squamous cell lung carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Over-expression of eukaryotic translation initiation factor 4 gamma 1 correlates with tumor progression and poor prognosis in nasopharyngeal carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

An alternative splicing isoform of eukaryotic initiation factor 4H promotes tumorigenesis in vivo and is a potential therapeutic target for human cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Structure of the eukaryotic initiation factor (eIF) 5 reveals a fold common to several translation factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

eIF5 has GDI activity necessary for translational control by eIF2 phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Overexpression of eIF5 or its protein mimic 5MP perturbs eIF2 function and induces ATF4 translation through delayed re-initiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Identification and characterization of eukaryotic initiation factor 5A-2

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Differential expression of eIF5A-1 and eIF5A-2 in human cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Eukaryotic translation initiation factor 5A2 (eIF5A2) regulates chemoresistance in colorectal cancer through epithelial mesenchymal transition

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Upregulation of eIF5B controls cell-cycle arrest and specific developmental stages

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

eIF5B increases ASAP1 expression to promote HCC proliferation and invasion

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Expression of eukaryotic initiation factor 5A and hypusine forming enzymes in glioblastoma patient samples: implications for new targeted therapies

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Eukaryotic initiation factor 5A-1 (eIF5A-1) as a diagnostic marker for aberrant proliferation in intraepithelial neoplasia of the vulva

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Identification of distinctive protein expression patterns in colorectal adenoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Overexpression of EIF5A2 promotes colorectal carcinoma cell aggressiveness by upregulating MTA1 through C-myc to induce epithelial-mesenchymaltransition.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Overexpression of EIF-5A2 predicts tumor recurrence and progression in pTa/pT1 urothelial carcinoma of the bladder.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Expression and amplification of eIF-5A2 in human epithelial ovarian tumors and overexpression of EIF-5A2 is a new independent predictor of outcome in patients with ovarian carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Overexpression of eIF5A-2 is an adverse prognostic marker of survival in stage I non-small cell lung cancer patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Mechanism of action of the wheat germ ribosome dissociation factor: Interaction with the 60 S subunit

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Eukaryotic initiation factor 6 mediates a continuum between 60S ribosome biogenesis and translation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Function and ribosomal localization of aIF6, a translational regulator shared by archaea and eukarya.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Eukaryotic initiation factor 6 selectively regulates Wnt signaling and beta-catenin protein synthesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

MicroRNA silencing through RISC recruitment of eIF6

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Isolation of a novel beta4 integrin-binding protein (p27(BBP)) highly expressed in epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Altered eIF6 and Dicer expression is associated with clinicopathological features in ovarian serous carcinoma patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Comparative proteomic analysis of all-trans-retinoic acid treatment reveals systematic posttranscriptional control mechanisms in acute promyelocytic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Overexpression of p27BBP in head and neck carcinomas and their lymph node metastases

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Functional clustering of metastasis proteins describes plastic adaptation resources of breast-cancer cells to new microenvironments

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Eukaryotic initiation factor 6 is rate-limiting in translation, growth and transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

RAS oncogenes: weaving a tumorigenic web

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

The receptor tyrosine kinase EphA2 promotes mammary adenocarcinoma tumorigenesis and metastatic progression in mice by amplifying ErbB2 signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Nuclear PI3K signaling in cell growth and tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

PAF-mediated MAPK signaling hyperactivation via LAMTOR3 induces pancreatic tumorigenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

AKT signaling in normal and malignant cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Structure-function insights into prokaryotic and eukaryotic translation initiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

The evolution of the TOR pathway and its role in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

4E-BP restrains eIF4E phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

mTOR Signalling in Health and Disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Activation of translation complex eIF4F is essential for the genesis and maintenance of the malignant phenotype in human mammary epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

A unifying model for mTORC1-mediated regulation of mRNA translation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

eIF4E/4E-BP ratio predicts the efficacy of mTOR targeted therapies

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Metformin inhibits mammalian target of rapamycin-dependent translation initiation in breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

The role of MNK proteins and eIF4E phosphorylation in breast cancer cell proliferation and survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Upregulation of the eIF4E signaling pathway contributes to the progression of gastric cancer, and targeting eIF4E by perifosine inhibits cell growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

mTOR signaling pathway in penile squamous cell carcinoma: pmTOR and peIF4E over expression correlate with aggressive tumor behavior.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Targeting of the MNK-eIF4E axis in blast crisis chronic myeloid leukemia inhibits leukemia stem cell function

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

mTOR Signaling in Protein Translation Regulation: Implications in Cancer Genesis and Therapeutic Interventions

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Role of p70S6K1-mediated phosphorylation of eIF4B and PDCD4 proteins in the regulation of protein synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Specific isoforms of translation initiation factor 4GI show differences in translational activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

eIF4GI links nutrient sensing by mTOR to cell proliferation and inhibition of autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

S6K1- and betaTRCP-mediated degradation of PDCD4 promotes protein translation and cell growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

The transformation suppressor Pdcd4 is a novel eukaryotic translation initiation factor 4A binding protein that inhibits translation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Epidermal expression of the translation inhibitor programmed cell death 4 suppresses tumorigenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Tumor suppressor protein Pdcd4 inhibits translation of p53 mRNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Inflammation and MiR-21 pathways functionally interact to downregulate PDCD4 in colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

MicroRNA-21 (miR-21) post-transcriptionally downregulates tumor suppressor PDCD4 and promotes cell transformation, proliferation, and metastasis in renal cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

miR-183 induces cell proliferation, migration, and invasion by regulating PDCD4 expression in the SW1990 pancreatic cancer cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Down-regulation of programmed cell death 4 (PDCD4) is associated with aromatase inhibitor resistance and a poor prognosis in estrogen receptor-positive breast cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Tumour suppressive function and modulation of programmed cell death 4 (PDCD4) in ovarian cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Dysregulation of miR-31 and miR-21 induced by zinc deficiency promotes esophageal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

mTOR-dependent transcriptional repression of Pdcd4 tumor suppressor in lung cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Helicobacter pylori promotes epithelial-mesenchymal transition in gastric cancer by downregulating programmed cell death protein 4 (PDCD4).

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Downregulation and pro-apoptotic effect of hypoxia-inducible factor 2 alpha in hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

A liaison between mTOR signaling, ribosome biogenesis and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Roles of the mammalian target of rapamycin, mTOR, in controlling ribosome biogenesis and protein synthesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

ERK and Akt signaling pathways function through parallel mechanisms to promote mTORC1 signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Intestinal cell kinase (ICK) promotes activation of mTOR complex 1 (mTORC1) through phosphorylation of Raptor Thr-908.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Regulation of mTOR complex 1 (mTORC1) by raptor Ser863 and multisite phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Oncogenic MAPK signaling stimulates mTORC1 activity by promoting RSK-mediated raptor phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

mTORC2 targets AGC kinases through Sin1-dependent recruitment

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

A cellular response linking eIF4AI activity to eIF4AII transcription.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Therapeutic suppression of translation initiation factor eIF4E expression reduces tumor growth without toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Targeting synthetic lethal interactions between Myc and the eIF4F complex impedes tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Mnk2 and Mnk1 are essential for constitutive and inducible phosphorylation of eukaryotic initiation factor 4E but not for cell growth or development

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Small-molecule inhibition of the interaction between the translation initiation factors eIF4E and eIF4G

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

The cap-translation inhibitor 4EGI-1 induces apoptosis in multiple myeloma through Noxa induction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Cap-translation inhibitor, 4EGI-1, restores sensitivity to ABT-737 apoptosis through cap-dependent and -independent mechanisms in chronic lymphocytic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Stimulation of mammalian translation initiation factor eIF4A activity by a small molecule inhibitor of eukaryotic translation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Expression of EIF3-p48/INT6, TID1 and Patched in cancer, a profiling of multiple tumor types and correlation of expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Detection of the Proto-oncogene eIF4E in Larynx and Hypopharynx Cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

Detection of the proto-oncogene eIF4E in surgical margins may predict recurrence in head and neck cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1010428317709805

21 January 2018

Identifiers

DOI

10.1177/1010428317709805

1 reference

11 September 2017

1 reference