Pathophysiology of Gastric NETs: Role of Gastrin and Menin (Q39368598)

9 July 2018

title

Pathophysiology of Gastric NETs: Role of Gastrin and Menin (English)

1 reference

9 July 2018

1 reference

Sinju Sundaresan

1

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9 July 2018

Anthony J Kang

series ordinal

2

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9 July 2018

Juanita L Merchant

series ordinal

3

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9 July 2018

publication date

1 July 2017

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9 July 2018

Current gastroenterology reports

published in

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9 July 2018

volume

19

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9 July 2018

issue

7

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9 July 2018

page(s)

32

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9 July 2018

publication type of scholarly work

review article

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Treatment Strategies for Metastatic Neuroendocrine Tumors of the Gastrointestinal Tract

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Management of neuroendocrine tumors.

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Management of gastric and duodenal neuroendocrine tumors

15 July 2018

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A short history of neuroendocrine tumours and their peptide hormones

15 July 2018

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Deletion of Men1 and somatostatin induces hypergastrinemia and gastric carcinoids

15 July 2018

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Pathology of Gastrointestinal Neuroendocrine Tumors: An Update

15 July 2018

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Safety of proton pump inhibitors and risk of gastric cancers: review of literature and pathophysiological mechanisms.

15 July 2018

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Islet Cells Serve as Cells of Origin of Pancreatic Gastrin-Positive Endocrine Tumors

15 July 2018

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Gastric neuroendocrine neoplasms and proton pump inhibitors: fact or coincidence?

15 July 2018

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Loss of Lrig1 leads to expansion of Brunner glands followed by duodenal adenomas with gastric metaplasia

15 July 2018

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Long-term proton pump inhibitor (PPI) use and the development of gastric pre-malignant lesions

15 July 2018

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Netazepide, a gastrin receptor antagonist, normalises tumour biomarkers and causes regression of type 1 gastric neuroendocrine tumours in a nonrandomised trial of patients with chronic atrophic gastritis

15 July 2018

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Gastrin: a distinct fate of neurogenin3 positive progenitor cells in the embryonic pancreas

15 July 2018

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Menin: a scaffold protein that controls gene expression and cell signaling

15 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5550324

Causes of death and prognostic factors in multiple endocrine neoplasia type 1: a prospective study: comparison of 106 MEN1/Zollinger-Ellison syndrome patients with 1613 literature MEN1 patients with or without pancreatic endocrine tumors

15 July 2018

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Conditional deletion of menin results in antral G cell hyperplasia and hypergastrinemia

15 July 2018

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Risk for gastric neoplasias in patients with chronic atrophic gastritis: a critical reappraisal

15 July 2018

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Gastric carcinoid in a patient infected with Helicobacter pylori: A new entity?

15 July 2018

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Everolimus for advanced pancreatic neuroendocrine tumors.

15 July 2018

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DAXX/ATRX, MEN1, and mTOR pathway genes are frequently altered in pancreatic neuroendocrine tumors

15 July 2018

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Neuroendocrine tumors of the stomach (gastric carcinoids) are on the rise: small tumors, small problems?

15 July 2018

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Multiple endocrine neoplasia type 1 deletion in pancreatic alpha-cells leads to development of insulinomas in mice

15 July 2018

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One hundred years after "carcinoid": epidemiology of and prognostic factors for neuroendocrine tumors in 35,825 cases in the United States

15 July 2018

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Pasireotide (SOM230): development, mechanism of action and potential applications

15 July 2018

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Allelic deletion of the MEN1 gene in duodenal gastrin and somatostatin cell neoplasms and their precursor lesions.

15 July 2018

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Mechanisms of disease: multiple endocrine neoplasia type 1-relation to chromatin modifications and transcription regulation.

15 July 2018

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Tumor suppressor menin: the essential role of nuclear localization signal domains in coordinating gene expression

15 July 2018

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Menin missense mutants associated with multiple endocrine neoplasia type 1 are rapidly degraded via the ubiquitin-proteasome pathway

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5550324

Conditional inactivation of the MEN1 gene leads to pancreatic and pituitary tumorigenesis but does not affect normal development of these tissues

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5550324

Of mice and MEN1: Insulinomas in a conditional mouse knockout

15 July 2018

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A mouse model of multiple endocrine neoplasia, type 1, develops multiple endocrine tumors

15 July 2018

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Brunner's glands: a structural, histochemical and pathological profile

15 July 2018

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Loss of heterozygosity in 11q13-14 regions in gastric neuroendocrine tumors not associated with multiple endocrine neoplasia type 1 syndrome.

15 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5550324

The role of transforming growth factor alpha in the enterochromaffin-like cell tumor autonomy in an African rodent mastomys

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5550324

Gastrinomas demonstrate amplification of the HER-2/neu proto-oncogene

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5550324

Revised classification of neuroendocrine tumours of the lung, pancreas and gut

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5550324

Neural crest origin of the endocrine polypeptide (APUD) cells of the gastrointestinal tract and pancreas

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5550324

The origin, development and differentiation of Brunner's glands in the rat

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5550324

The APUD cell concept and its implications in pathology

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5550324

Gastric ECL-cell hyperplasia and carcinoids in rodents following chronic administration of H2-antagonists SK&F 93479 and oxmetidine and omeprazole

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5550324

H2-receptor blockade induces peptide YY and enteroglucagon-secreting gastric carcinoids in mastomys

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5550324

Role of gastrin as a trophic hormone

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5550324

Electron Microscope Study on Endocrine Cells and Tumor Cells in the Glandular Stomach of <i>Praomys (Mastomys) natalensis</i>

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5550324

Netazepide, a gastrin/cholecystokinin-2 receptor antagonist, can eradicate gastric neuroendocrine tumours in patients with autoimmune chronic atrophic gastritis

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5550324

New and Emerging Treatment Options for Gastroenteropancreatic Neuroendocrine Tumors.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5550324

Occurrence of gastric cancer and carcinoids in atrophic gastritis during prospective long-term follow up.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5550324

Application of an intracellular stability test of a novel missense menin mutant to the diagnosis of multiple endocrine neoplasia type 1.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5550324

Menin missense mutants encoded by the MEN1 gene that are targeted to the proteasome: restoration of expression and activity by CHIP siRNA.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5550324

Correlation of mutant menin stability with clinical expression of multiple endocrine neoplasia type 1 and its incomplete forms

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5550324

The CCK(2) receptor antagonist, YF476, inhibits Mastomys ECL cell hyperplasia and gastric carcinoid tumor development

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5550324

Siegfried oberndorfer and the evolution of carcinoid disease

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5550324

Mutation of the MENIN gene in sporadic pancreatic endocrine tumors

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5550324

Precursor lesions in patients with multiple endocrine neoplasia type 1-associated duodenal gastrinomas

21 August 2018

1 reference

12 December 2020

Gastrin receptor genes are expressed in gastric parietal and enterochromaffin-like cells of Mastomys natalensis

1 reference

12 December 2020

An Unusual Case of Multiple Gastric Carcinoids Associated with Diffuse Endocrine Cell Hyperplasia and Parietal Cell Hypertrophy

1 reference

12 December 2020

Gastrin stimulates the self-replication rate of enterochromaffinlike cells in the rat stomach. Effects of omeprazole, ranitidine, and gastrin-17 in intact and antrectomized rats

1 reference

12 December 2020

Immunohistochemical localization of acidic fibroblast growth factor in normal human enterochromaffin cells and related gastrointestinal tumours

1 reference

12 December 2020

Development of carcinoid tumors of the glandular stomach and effects of eradication in Helicobacter pylori-infected Mongolian gerbils

1 reference

12 December 2020

Phosphorylation of the menin tumor suppressor protein on serine 543 and serine 583

1 reference

12 December 2020

Expression of vesicular monoamine transporters in endocrine hyperplasia and endocrine tumors of the oxyntic stomach

1 reference

12 December 2020

The ulceration-associated cell lineage (UACL) reiterates the Brunner's gland differentiation programme but acquires the proliferative organization of the gastric gland

1 reference

12 December 2020

Ultrastructure of ECL cells in Mastomys after long-term treatment with H2 receptor antagonist loxtidine

1 reference

12 December 2020

Achlorhydria, parietal cell hyperplasia, and multiple gastric carcinoids: a new disorder

1 reference

12 December 2020

Her-2/neu expression and gene amplification in gastrinomas: correlations with tumor biology, growth, and aggressiveness

1 reference

12 December 2020

Immunolocalization of transforming growth factor-alpha and epidermal growth factor receptor in the rat gastroduodenal area

1 reference

12 December 2020

Enterochromaffin-like cell pathobiology of mastomys

1 reference

12 December 2020

Germline mutations of the MEN1 gene in familial multiple endocrine neoplasia type 1 and related states

1 reference

12 December 2020

Long-term high-dose proton pump inhibitor administration to Helicobacter pylori-infected Mongolian gerbils enhances neuroendocrine tumor development in the glandular stomach

1 reference

12 December 2020

Localization of the murine cholecystokinin A and B receptor genes

1 reference

12 December 2020

Growth Factor Effects on Apoptosis of Rat Gastric Enterochromaffin-Like Cells1

1 reference

12 December 2020

10.1007/S11894-017-0572-Y

Identifiers

DOI

1 reference

9 July 2018

PMC publication ID

5550324

1 reference

9 July 2018

PubMed publication ID

28608155

1 reference

9 July 2018