Human interstitial cellular model in therapeutics of heart valve calcification (Q39325703)

11 September 2017

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title

Human interstitial cellular model in therapeutics of heart valve calcification (English)

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11 September 2017

Caimei He

1

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11 September 2017

Hai Tang

2

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11 September 2017

Zijian Mei

3

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11 September 2017

Nichujie Li

4

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11 September 2017

Zhi Zeng

5

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11 September 2017

Kwame Oteng Darko

6

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11 September 2017

Yulong Yin

7

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11 September 2017

Chien-An Andy Hu

8

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11 September 2017

Xiaoping Yang

9

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11 September 2017

23 May 2017

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11 September 2017

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https://scigraph.springernature.com/pub.10.1007/s00726-017-2432-3

11 September 2017

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21 January 2018

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Lipopolysaccharide stimulation of human aortic valve interstitial cells activates inflammation and osteogenesis

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Cultured interstitial cells from human heart valves express both specific skeletal muscle and non-muscle markers

21 January 2018

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osteoprotegerin-deficient mice develop early onset osteoporosis and arterial calcification

21 January 2018

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21 January 2018

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Impact of hypertension and renin-angiotensin system inhibitors in aortic stenosis

21 January 2018

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21 January 2018

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Notch1 Mutation Leads to Valvular Calcification Through Enhanced Myofibroblast Mechanotransduction

21 January 2018

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Molecular and functional characteristics of heart-valve interstitial cells

21 January 2018

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Angiotensin receptor blockers are associated with reduced fibrosis and interleukin-6 expression in calcific aortic valve disease.

21 January 2018

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Adult aortic valve interstitial cells have greater responses to toll-like receptor 4 stimulation

21 January 2018

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Stiffness and adhesivity control aortic valve interstitial cell behavior within hyaluronic acid based hydrogels

21 January 2018

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Three-dimensional printed trileaflet valve conduits using biological hydrogels and human valve interstitial cells.

21 January 2018

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Loss of β-catenin promotes chondrogenic differentiation of aortic valve interstitial cells

21 January 2018

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Valve interstitial cell tensional homeostasis directs calcification and extracellular matrix remodeling processes via RhoA signaling

21 January 2018

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Synergy between sphingosine 1-phosphate and lipopolysaccharide signaling promotes an inflammatory, angiogenic and osteogenic response in human aortic valve interstitial cells

21 January 2018

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Calcific nodule morphogenesis by heart valve interstitial cells is strain dependent

21 January 2018

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21 January 2018

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Mutations in NOTCH1 cause aortic valve disease

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21 January 2018

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21 January 2018

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21 January 2018

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Altered DNA Methylation of Long Noncoding RNA H19 in Calcific Aortic Valve Disease Promotes Mineralization by Silencing NOTCH1.

21 January 2018

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Fibroblast growth factor-2 promotes in vitro heart valve interstitial cell repair through the Akt1 pathway.

21 January 2018

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Vascular calcification in type-2 diabetes and cardiovascular disease: Integrative roles for OPG, RANKL and TRAIL.

21 January 2018

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VBP15, a novel anti-inflammatory and membrane-stabilizer, improves muscular dystrophy without side effects

21 January 2018

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Aortic valve stenosis: an active atheroinflammatory process

21 January 2018

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21 January 2018

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21 January 2018

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Cadherin-11 regulates cell-cell tension necessary for calcific nodule formation by valvular myofibroblasts

21 January 2018

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The P2Y₂ receptor promotes Wnt3a- and EGF-induced epithelial tubular formation by IEC6 cells by binding to integrins

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Modulation of human valve interstitial cell phenotype and function using a fibroblast growth factor 2 formulation

21 January 2018

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Collagenases and cracks in the plaque

21 January 2018

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21 January 2018

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Runx2 Deletion in Smooth muscle Cells Inhibits Vascular Osteochondrogenesis and Calcification but not Atherosclerotic Lesion Formation.

21 January 2018

1 reference

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Usefulness of serum carboxy-terminal propeptide of procollagen type I in assessment of the cardioreparative ability of antihypertensive treatment in hypertensive patients

21 January 2018

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Viral and bacterial patterns induce TLR-mediated sustained inflammation and calcification in aortic valve interstitial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00726-017-2432-3

Elevated expression of lipoprotein-associated phospholipase A2 in calcific aortic valve disease: implications for valve mineralization

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00726-017-2432-3

Association between metformin use and below-the-knee arterial calcification score in type 2 diabetic patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00726-017-2432-3

Comparison of calcification potential of valvular interstitial cells isolated from individual aortic valve cusps

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00726-017-2432-3

Valvular interstitial cell seeded poly(glycerol sebacate) scaffolds: toward a biomimetic in vitro model for heart valve tissue engineering

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00726-017-2432-3

Calcific aortic valve stenosis: methods, models, and mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00726-017-2432-3

Heart Disease and Stroke Statistics-2016 Update: A Report From the American Heart Association

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00726-017-2432-3

Radiation induces osteogenesis in human aortic valve interstitial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00726-017-2432-3

ox-LDL induces PiT-1 expression in human aortic valve interstitial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00726-017-2432-3

Interleukin-1 Beta induces an inflammatory phenotype in human aortic valve interstitial cells through nuclear factor kappa Beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00726-017-2432-3

SOX9 binds DNA, activates transcription, and coexpresses with type II collagen during chondrogenesis in the mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00726-017-2432-3

CD34-negative mesenchymal stem-like cells may act as the cellular origin of human aortic valve calcification.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00726-017-2432-3

Cross-talk of receptor activator of nuclear factor-κB ligand signaling with renin-angiotensin system in vascular calcification.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00726-017-2432-3

Role of human valve interstitial cells in valve calcification and their response to atorvastatin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00726-017-2432-3

Osteopontin alters endothelial and valvular interstitial cell behaviour in calcific aortic valve stenosis through HMGB1 regulation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00726-017-2432-3

Reduced sox9 function promotes heart valve calcification phenotypes in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00726-017-2432-3

Targeting vasoactive peptides for managing calcific aortic valve disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00726-017-2432-3

Vascular calcification and bone disease: the calcification paradox

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00726-017-2432-3

Noggin attenuates the osteogenic activation of human valve interstitial cells in aortic valve sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00726-017-2432-3

Osteopontin-CD44v6 interaction mediates calcium deposition via phospho-Akt in valve interstitial cells from patients with noncalcified aortic valve sclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00726-017-2432-3

The P2Y2 nucleotide receptor is an inhibitor of vascular calcification.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00726-017-2432-3

The role of Lrp5/6 in cardiac valve disease: experimental hypercholesterolemia in the ApoE-/- /Lrp5-/- mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00726-017-2432-3

Human Aortic Valve Calcification Is Associated With an Osteoblast Phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00726-017-2432-3

Calcific aortic stenosis: an update

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00726-017-2432-3

VBP15: preclinical characterization of a novel anti-inflammatory delta 9,11 steroid

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00726-017-2432-3

A novel kind of tumor type-characteristic junction: plakophilin-2 as a major protein of adherens junctions in cardiac myxomata

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00726-017-2432-3

Surface chemistry regulates valvular interstitial cell differentiation in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00726-017-2432-3

On intrinsic stress fiber contractile forces in semilunar heart valve interstitial cells using a continuum mixture model

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00726-017-2432-3

On the Functional Role of Valve Interstitial Cell Stress Fibers: A Continuum Modeling Approach.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00726-017-2432-3

Effect of biodegradation and de novo matrix synthesis on the mechanical properties of valvular interstitial cell-seeded polyglycerol sebacate-polycaprolactone scaffolds

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00726-017-2432-3

Progression of vascular calcification is increased with statin use in the Veterans Affairs Diabetes Trial (VADT).

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00726-017-2432-3

Heart valve health, disease, replacement, and repair: a 25-year cardiovascular pathology perspective

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00726-017-2432-3

Notch signaling pathway enhances bone morphogenetic protein 2 (BMP2) responsiveness of Msx2 gene to induce osteogenic differentiation and mineralization of vascular smooth muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00726-017-2432-3

Spatial heterogeneity of endothelial phenotypes correlates with side-specific vulnerability to calcification in normal porcine aortic valves.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00726-017-2432-3

Microfilaments facilitate TLR4-mediated ICAM-1 expression in human aortic valve interstitial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00726-017-2432-3

BMP-2 and TGF-β1 mediate biglycan-induced pro-osteogenic reprogramming in aortic valve interstitial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00726-017-2432-3

Comparative study of human aortic and mitral valve interstitial cell gene expression and cellular function

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00726-017-2432-3

Lazaroid U-74389G inhibits the osteoblastic differentiation of IL-1β-indcued aortic valve interstitial cells through glucocorticoid receptor and inhibition of NF-κB pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00726-017-2432-3

Swine as models in biomedical research and toxicology testing

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00726-017-2432-3

Valve interstitial cell shape modulates cell contractility independent of cell phenotype.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00726-017-2432-3

The cardiac valve interstitial cell

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00726-017-2432-3

The effects of combined cyclic stretch and pressure on the aortic valve interstitial cell phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00726-017-2432-3

Coronary Artery Calcification Is Related to Inflammation in Rheumatoid Arthritis: A Long-Term Follow-Up Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00726-017-2432-3

Hydrogels preserve native phenotypes of valvular fibroblasts through an elasticity-regulated PI3K/AKT pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00726-017-2432-3

High-mobility group box-1 protein induces osteogenic phenotype changes in aortic valve interstitial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00726-017-2432-3

Osteoprotegerin inhibits aortic valve calcification and preserves valve function in hypercholesterolemic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00726-017-2432-3

NOTCH1 regulates matrix gla protein and calcification gene networks in human valve endothelium

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00726-017-2432-3

Differential expression of cartilage and bone-related proteins in pediatric and adult diseased aortic valves

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00726-017-2432-3

Reversal of myofibroblastic activation by polyunsaturated fatty acids in valvular interstitial cells from aortic valves. Role of RhoA/G-actin/MRTF signalling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00726-017-2432-3

Angiotensin II promotes an osteoblast-like phenotype in porcine aortic valve myofibroblasts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00726-017-2432-3

Wnt3a/β-catenin increases proliferation in heart valve interstitial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00726-017-2432-3

Bone morphogenic protein 2 induces Runx2 and osteopontin expression in human aortic valve interstitial cells: role of Smad1 and extracellular signal-regulated kinase 1/2

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00726-017-2432-3

Pro-osteogenic phenotype of human aortic valve interstitial cells is associated with higher levels of Toll-like receptors 2 and 4 and enhanced expression of bone morphogenetic protein 2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00726-017-2432-3

Notch1 promotes the pro-osteogenic response of human aortic valve interstitial cells via modulation of ERK1/2 and nuclear factor-κB activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00726-017-2432-3

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00726-017-2432-3

Interleukin 18 promotes myofibroblast activation of valvular interstitial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00726-017-2432-3

The adhering junctions of valvular interstitial cells: molecular composition in fetal and adult hearts and the comings and goings of plakophilin-2 in situ, in cell culture and upon re-association with scaffolds

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00726-017-2432-3

10.1007/S00726-017-2432-3

21 January 2018

Identifiers

DOI

1 reference

11 September 2017

1 reference