The telomerase reverse transcriptase is limiting and necessary for telomerase function in vivo. (Q39120582)

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2 November 2019

title

The telomerase reverse transcriptase is limiting and necessary for telomerase function in vivo (English)

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2 November 2019

10

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2 November 2019

M Prakash Hande

3

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2 November 2019

David Siderovski

8

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2 November 2019

author name string

Y Liu

1

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2 November 2019

B E Snow

2

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2 November 2019

D Yeung

4

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2 November 2019

N J Erdmann

5

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2 November 2019

A Wakeham

6

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2 November 2019

A Itie

7

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2 November 2019

P M Lansdorp

9

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2 November 2019

L Harrington

11

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2 November 2019

publication date

1 November 2000

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2 November 2019

language of work or name

English

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number of pages

4

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inferred from page(s)

published in

Current Biology

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2 November 2019

volume

10

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2 November 2019

issue

22

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2 November 2019

page(s)

1459-1462

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Telomere shortening and tumor formation by mouse cells lacking telomerase RNA

2 November 2019

cites work

1 reference

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7 January 2021

Telomere shortening in mTR-/- embryos is associated with failure to close the neural tube

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7 January 2021

Disease states associated with telomerase deficiency appear earlier in mice with short telomeres

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7 January 2021

Essential role of mouse telomerase in highly proliferative organs

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7 January 2021

Longevity, Stress Response, and Cancer in Aging Telomerase-Deficient Mice

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7 January 2021

Human telomerase contains evolutionarily conserved catalytic and structural subunits

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7 January 2021

Reconstitution of human telomerase with the template RNA component hTR and the catalytic protein subunit hTRT

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7 January 2021

Telomerase activation by hTRT in human normal fibroblasts and hepatocellular carcinomas

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7 January 2021

Extension of life-span by introduction of telomerase into normal human cells

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7 January 2021

Reconstitution of telomerase activity in normal human cells leads to elongation of telomeres and extended replicative life span

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7 January 2021

Reconstitution of human telomerase activity in vitro

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7 January 2021

Severe growth defect in mouse cells lacking the telomerase RNA component

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7 January 2021

Presence of telomeric G-strand tails in the telomerase catalytic subunit TERT knockout mice

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7 January 2021

Specific Association of Human Telomerase Activity with Immortal Cells and Cancer

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7 January 2021

Identification of a specific telomere terminal transferase activity in Tetrahymena extracts

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7 January 2021

The human telomere terminal transferase enzyme is a ribonucleoprotein that synthesizes TTAGGG repeats

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7 January 2021

Telomere length dynamics in human lymphocyte subpopulations measured by flow cytometry

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7 January 2021

Reverse transcriptase motifs in the catalytic subunit of telomerase

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7 January 2021

Telomerase Catalytic Subunit Homologs from Fission Yeast and Human

1 reference

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7 January 2021

Disruption of the telomerase catalytic subunit gene from Arabidopsis inactivates telomerase and leads to a slow loss of telomeric DNA

1 reference

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7 January 2021

TLC1: template RNA component of Saccharomyces cerevisiae telomerase

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7 January 2021

Three Ever Shorter Telomere (EST) genes are dispensable for in vitro yeast telomerase activity

1 reference

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7 January 2021

Telomere shortening and apoptosis in telomerase-inhibited human tumor cells

1 reference

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7 January 2021

Inhibition of telomerase limits the growth of human cancer cells

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7 January 2021

Inhibition of human telomerase in immortal human cells leads to progressive telomere shortening and cell death

1 reference

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7 January 2021

Telomeres in the mouse have large inter-chromosomal variations in the number of T2AG3 repeats

1 reference

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7 January 2021

10.1016/S0960-9822(00)00805-8

Identifiers

DOI

1 reference

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2 November 2019

1 reference