Functions of the Tumor Suppressors p53 and Rb in Actin Cytoskeleton Remodeling (Q39080969)

8 September 2017

10 references

3 April 2019

12 October 2019

28 November 2019

11 December 2019

18 December 2019

19 December 2019

20 December 2019

10 August 2020

8 February 2021

31 July 2022

Functions of the Tumor Suppressors p53 and Rb in Actin Cytoskeleton Remodeling (English)

1 reference

8 September 2017

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3 April 2019

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12 October 2019

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28 November 2019

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11 December 2019

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18 December 2019

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20 December 2019

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10 August 2020

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8 February 2021

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28078303%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Keiko Kawauchi

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28078303%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

author name string

Takahiro Ebata

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28078303%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

language of work or name

English

0 references

publication date

18 December 2016

11 references

BioMed Research International

8 September 2017

3 April 2019

12 October 2019

28 November 2019

11 December 2019

18 December 2019

19 December 2019

20 December 2019

10 August 2020

8 February 2021

31 July 2022

11 references

3 April 2019

12 October 2019

28 November 2019

11 December 2019

18 December 2019

19 December 2019

20 December 2019

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28078303%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

10 August 2020

8 February 2021

31 July 2022

2016

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28078303%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

page(s)

9231057

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28078303%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution 4.0 International

9 June 2020

copyright license

start time

1 January 2016

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

1 reference

April 2022 Public Data File from Crossref

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9 September 2017

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Implication of tumor microenvironment in chemoresistance: tumor-associated stromal cells protect tumor cells from cell death

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9 September 2017

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9 September 2017

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9 September 2017

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9 September 2017

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9 September 2017

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9 September 2017

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9 September 2017

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9 September 2017

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9 September 2017

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9 September 2017

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9 September 2017

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9 September 2017

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Adhesion signaling - crosstalk between integrins, Src and Rho.

9 September 2017

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Environmental sensing through focal adhesions

9 September 2017

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The structure of the ankyrin-binding site of -spectrin reveals how tandem spectrin-repeats generate unique ligand-binding properties

9 September 2017

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Mechanics, malignancy, and metastasis: the force journey of a tumor cell

9 September 2017

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Phosphorylation of p130Cas initiates Rac activation and membrane ruffling

9 September 2017

1 reference

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Cadherin-11 promotes the metastasis of prostate cancer cells to bone

9 September 2017

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Mechanisms to suppress multipolar divisions in cancer cells with extra centrosomes

9 September 2017

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9 September 2017

Paxillin comes of age

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Specialized podosome- or invadopodia-like structures (PILS) for focal trabecular meshwork extracellular matrix turnover

9 September 2017

1 reference

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Blebs lead the way: how to migrate without lamellipodia

9 September 2017

1 reference

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Cell motility through plasma membrane blebbing

9 September 2017

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Lamellipodia and filopodia in metastasis and invasion

9 September 2017

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Migratory neighbors and distant invaders: tumor-associated niche cells

9 September 2017

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Cell adhesion-dependent cofilin serine 3 phosphorylation by the integrin-linked kinase.c-Src complex

9 September 2017

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Oncogenes and tumour suppressors take on centrosomes

9 September 2017

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Loss of p53 promotes RhoA-ROCK-dependent cell migration and invasion in 3D matrices

9 September 2017

1 reference

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Increased tumor cell dissemination and cellular senescence in the absence of beta1-integrin function

9 September 2017

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Are interactions with p63 and p73 involved in mutant p53 gain of oncogenic function?

9 September 2017

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p53 in health and disease

9 September 2017

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Notch1 is a p53 target gene involved in human keratinocyte tumor suppression through negative regulation of ROCK1/2 and MRCKalpha kinases

9 September 2017

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The matrix corroded: podosomes and invadopodia in extracellular matrix degradation

9 September 2017

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Muscle cachexia is regulated by a p53-PW1/Peg3-dependent pathway.

9 September 2017

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RhoE is a pro-survival p53 target gene that inhibits ROCK I-mediated apoptosis in response to genotoxic stress

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5203884

Force Sensing by Mechanical Extension of the Src Family Kinase Substrate p130Cas

9 September 2017

1 reference

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RB and cell cycle progression

9 September 2017

1 reference

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The myocardin family of transcriptional coactivators: versatile regulators of cell growth, migration, and myogenesis

9 September 2017

1 reference

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Staying in shape with formins

9 September 2017

1 reference

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Tensional homeostasis and the malignant phenotype

9 September 2017

1 reference

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Focal adhesion kinase: in command and control of cell motility

9 September 2017

1 reference

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Paxillin: adapting to change

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5203884

Cloning and characterization of the promoter region of human focal adhesion kinase gene: nuclear factor kappa B and p53 binding sites

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5203884

Role of RhoA, mDia, and ROCK in cell shape-dependent control of the Skp2-p27kip1 pathway and the G1/S transition

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5203884

ONCOMINE: a cancer microarray database and integrated data-mining platform

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5203884

MyoD distal regulatory region contains an SRF binding CArG element required for MyoD expression in skeletal myoblasts and during muscle regeneration.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5203884

The integrin-actin connection, an eternal love affair

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5203884

Decision making by p53: life, death and cancer

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5203884

Role of integrins in endothelial mechanosensing of shear stress

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5203884

Live or let die: the cell's response to p53

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5203884

Molecular architecture of adherens junctions

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5203884

Spectrin and ankyrin-based pathways: metazoan inventions for integrating cells into tissues

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5203884

Post-translational modifications and activation of p53 by genotoxic stresses

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5203884

Proliferation, cell cycle and apoptosis in cancer

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5203884

Cofilin phosphorylation by protein kinase testicular protein kinase 1 and its role in integrin-mediated actin reorganization and focal adhesion formation

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5203884

Molecular characterization of human tensin

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5203884

The Rb/E2F pathway: expanding roles and emerging paradigms

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5203884

Gelsolin and ADF/cofilin enhance the actin dynamics of motile cells

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5203884

RhoA signaling via serum response factor plays an obligatory role in myogenic differentiation

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5203884

Fibronectin-integrin interactions

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5203884

The retinoblastoma protein and cell cycle control

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5203884

Re-expression of the alpha 2 beta 1 integrin abrogates the malignant phenotype of breast carcinoma cells

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5203884

Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5203884

Activation of p53 pathway by Nutlin-3a inhibits the expression of the therapeutic target α5 integrin in colon cancer cells

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5203884

9 September 2017

EMT and tumor metastasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5203884

Integrin α5β1 plays a critical role in resistance to temozolomide by interfering with the p53 pathway in high-grade glioma.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5203884

p130Cas-dependent actin remodelling regulates myogenic differentiation.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5203884

p53-mediated transcriptional regulation and activation of the actin cytoskeleton regulatory RhoC to LIMK2 signaling pathway promotes cell survival

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5203884

A critical role of integrin-linked kinase, ch-TOG and TACC3 in centrosome clustering in cancer cells

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5203884

Mutant p53(R175H) upregulates Twist1 expression and promotes epithelial-mesenchymal transition in immortalized prostate cells.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5203884

Regulation of Cdc42-mediated morphological effects: a novel function for p53.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5203884

Mutant p53 drives invasion by promoting integrin recycling

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5203884

Negative regulation of beta4 integrin transcription by homeodomain-interacting protein kinase 2 and p53 impairs tumor progression

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5203884

p53 controls cancer cell invasion by inducing the MDM2-mediated degradation of Slug

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5203884

Conditional RNA interference in vivo to study mutant p53 oncogenic gain of function on tumor malignancy.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5203884

Cadherin-11-mediated interactions with bone marrow stromal/osteoblastic cells support selective colonization of breast cancer cells in bone.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5203884

CDH11 expression is associated with survival in patients with osteosarcoma

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5203884

The mitochondrial protease HtrA2 is regulated by Parkinson's disease-associated kinase PINK1.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5203884

Caldesmon suppresses cancer cell invasion by regulating podosome/invadopodium formation

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5203884

The cleavage mode of apoptotic nuclear vesiculation is related to plasma membrane blebbing and depends on actin reorganization.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5203884

Tumor suppressor p53 restricts Ras stimulation of RhoA and cancer cell motility

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5203884

Interaction of human Arp2/3 complex and the Listeria monocytogenes ActA protein in actin filament nucleation

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5203884

Loss of p53 enhances NF-κB-dependent lamellipodia formation.

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5203884

p53 suppresses Src-induced podosome and rosette formation and cellular invasiveness through the upregulation of caldesmon

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5203884

Beyond focal adhesions: integrin-linked kinase associates with tubulin and regulates mitotic spindle organization.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5203884

Integrin-linked kinase activity regulates Rac- and Cdc42-mediated actin cytoskeleton reorganization via alpha-PIX.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5203884

Drosophila Spire is an actin nucleation factor

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5203884

Force-dependent conformational switch of α-catenin controls vinculin binding

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5203884

p19Arf-p53 tumor suppressor pathway regulates cell motility by suppression of phosphoinositide 3-kinase and Rac1 GTPase activities

4 November 2018

1 reference

12 December 2020

Id1-induced inhibition of p53 facilitates endothelial cell migration and tube formation by regulating the expression of beta1-integrin

1 reference

12 December 2020

Cadherin switching in human prostate cancer progression

1 reference

12 December 2020

1 reference

12 December 2020

The mammary progenitor marker CD61/beta3 integrin identifies cancer stem cells in mouse models of mammary tumorigenesis

1 reference

12 December 2020

Identifiers

DOI

10.1155/2016/9231057

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28078303%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28078303%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

1 reference