Pharmacological and genomic profiling identifies NF-κB-targeted treatment strategies for mantle cell lymphoma (Q39040982)

8 September 2017

title

Pharmacological and genomic profiling identifies NF-κB-targeted treatment strategies for mantle cell lymphoma (English)

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8 September 2017

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22

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12 June 2020

Rami Rahal

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12 June 2020

Rodrigo Romero

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12 June 2020

Rodrigo Romero

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12 June 2020

Robert Kridel

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12 June 2020

John Monahan

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12 June 2020

author name string

Mareike Frick

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12 June 2020

Joshua M Korn

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12 June 2020

Fong Chun Chan

7

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12 June 2020

Barbara Meissner

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12 June 2020

Hyo-eun Bhang

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12 June 2020

Dave Ruddy

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Audrey Kauffmann

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Ali Farsidjani

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Adnan Derti

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Daniel Rakiec

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Tara Naylor

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Estelle Pfister

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Steve Kovats

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Sunkyu Kim

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Kerstin Dietze

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Bernd Dörken

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Christian Steidl

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Michael Hummel

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12 June 2020

Michael P Morrissey

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Christine Fritsch

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William R Sellers

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Vesselina G Cooke

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Georg Lenz

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Frank Stegmeier

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Randy D Gascoyne

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12 June 2020

publication date

22 December 2013

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8 September 2017

language of work or name

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12 June 2020

volume

20

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12 June 2020

issue

1

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12 June 2020

page(s)

87-92

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Control of canonical NF-kappaB activation through the NIK-IKK complex pathway

12 June 2020

cites work

1 reference

12 December 2020

Frequent engagement of the classical and alternative NF-kappaB pathways by diverse genetic abnormalities in multiple myeloma

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12 December 2020

Signal-induced site-specific phosphorylation targets I kappa B alpha to the ubiquitin-proteasome pathway

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12 December 2020

Noncanonical NF-kappaB activation requires coordinated assembly of a regulatory complex of the adaptors cIAP1, cIAP2, TRAF2 and TRAF3 and the kinase NIK.

1 reference

12 December 2020

Targeting BTK with ibrutinib in relapsed or refractory mantle-cell lymphoma

1 reference

12 December 2020

Oncogenic CARD11 mutations in human diffuse large B cell lymphoma

1 reference

12 December 2020

Discovery of 3-(1H-indol-3-yl)-4-[2-(4-methylpiperazin-1-yl)quinazolin-4-yl]pyrrole-2,5-dione (AEB071), a potent and selective inhibitor of protein kinase C isotypes

1 reference

12 December 2020

1 reference

12 December 2020

NF-κB-inducing kinase activates IKK-α by phosphorylation of Ser-176

1 reference

12 December 2020

Coupling of a signal response domain in I kappa B alpha to multiple pathways for NF-kappa B activation

1 reference

12 December 2020

An integrated map of genetic variation from 1,092 human genomes

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12 December 2020

The lymphotoxin-beta receptor induces different patterns of gene expression via two NF-kappaB pathways

1 reference

12 December 2020

Structure–Activity Relationship and Pharmacokinetic Studies of Sotrastaurin (AEB071), a Promising Novel Medicine for Prevention of Graft Rejection and Treatment of Psoriasis

1 reference

12 December 2020

Nonredundant and complementary functions of TRAF2 and TRAF3 in a ubiquitination cascade that activates NIK-dependent alternative NF-kappaB signaling

1 reference

12 December 2020

Essential role of MALT1 protease activity in activated B cell-like diffuse large B-cell lymphoma.

1 reference

12 December 2020

Activation by IKKalpha of a second, evolutionary conserved, NF-kappa B signaling pathway

1 reference

12 December 2020

Antigen receptor signaling to NF-kappaB via CARMA1, BCL10, and MALT1.

1 reference

12 December 2020

Small molecule inhibitors of IkappaB kinase are selectively toxic for subgroups of diffuse large B-cell lymphoma defined by gene expression profiling.

1 reference

12 December 2020

TopHat: discovering splice junctions with RNA-Seq

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12 December 2020

Hodgkin lymphoma requires stabilized NIK and constitutive RelB expression for survival

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12 December 2020

Natural genetic variation caused by small insertions and deletions in the human genome

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12 December 2020

The Bruton tyrosine kinase inhibitor PCI-32765 blocks B-cell activation and is efficacious in models of autoimmune disease and B-cell malignancy

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12 December 2020

VarScan 2: somatic mutation and copy number alteration discovery in cancer by exome sequencing

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12 December 2020

PTEN loss defines a PI3K/AKT pathway-dependent germinal center subtype of diffuse large B-cell lymphoma

1 reference

12 December 2020

Malt1-dependent RelB cleavage promotes canonical NF-kappaB activation in lymphocytes and lymphoma cell lines.

1 reference

12 December 2020

Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation

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12 December 2020

Integrative Genomics Viewer (IGV): high-performance genomics data visualization and exploration

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12 December 2020

COSMIC: mining complete cancer genomes in the Catalogue of Somatic Mutations in Cancer

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12 December 2020

How I treat mantle cell lymphoma.

1 reference

12 December 2020

The Sequence Alignment/Map format and SAMtools

1 reference

12 December 2020

Single-vector inducible lentiviral RNAi system for oncology target validation

1 reference

12 December 2020

Chronic active B-cell-receptor signalling in diffuse large B-cell lymphoma

1 reference

12 December 2020

Classical and/or alternative NF-kappaB pathway activation in multiple myeloma

1 reference

12 December 2020

A critical role for the NFkB pathway in multiple myeloma

1 reference

12 December 2020

BAFF-induced NEMO-independent processing of NF-kappa B2 in maturing B cells

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12 December 2020

A framework for variation discovery and genotyping using next-generation DNA sequencing data

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12 December 2020

PTEN-deficient cancers depend on PIK3CB.

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12 December 2020

Protein kinase C inhibitor sotrastaurin selectively inhibits the growth of CD79 mutant diffuse large B-cell lymphomas

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12 December 2020

Regulation of the NF-kappaB-inducing kinase by tumor necrosis factor receptor-associated factor 3-induced degradation

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12 December 2020

A program for annotating and predicting the effects of single nucleotide polymorphisms, SnpEff: SNPs in the genome of Drosophila melanogaster strain w1118; iso-2; iso-3

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12 December 2020

The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity

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12 December 2020

Cooperative signaling through the signal transducer and activator of transcription 3 and nuclear factor-{kappa}B pathways in subtypes of diffuse large B-cell lymphoma

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12 December 2020

Chronic myeloid leukemia: 2012 update on diagnosis, monitoring, and management

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12 December 2020

IκB-ζ controls the constitutive NF-κB target gene network and survival of ABC DLBCL

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12 December 2020

RING domain E3 ubiquitin ligases

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12 December 2020

A loss-of-function RNA interference screen for molecular targets in cancer

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12 December 2020

Prostate stem cell antigen is overexpressed in prostate cancer metastases

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Crossref

https://api.crossref.org/works/10.1038%2FNM.3435

7 January 2021