Capsaicin induces apoptosis in human small cell lung cancer via the TRPV6 receptor and the calpain pathway (Q38989979)

8 September 2017

Capsaicin induces apoptosis in human small cell lung cancer via the TRPV6 receptor and the calpain pathway (English)

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8 September 2017

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Jamie K Lau

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Kathleen C Brown

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Aaron M Dom

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Theodore R Witte

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Brent A Thornhill

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Clayton M Crabtree

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Haley E Perry

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J Michael Brown

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John G Ball

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Rebecca G Creel

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C Luke Damron

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William D Rollyson

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Cathryn D Stevenson

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W Elaine Hardman

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Monica A Valentovic

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A Betts Carpenter

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Piyali Dasgupta

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1 August 2014

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1190-1201

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describes a project that uses

8 September 2017

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4072851/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

exact match

https://scigraph.springernature.com/pub.10.1007/s10495-014-1007-y

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cites work

Therapeutic procedure in small cell lung cancer

1 reference

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Nicotine induces the up-regulation of the α7-nicotinic receptor (α7-nAChR) in human squamous cell lung cancer cells via the Sp1/GATA protein pathway

9 September 2017

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Transient receptor potential ion channels: powerful regulators of cell function.

9 September 2017

1 reference

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In vivo detection of human TRPV6-rich tumors with anti-cancer peptides derived from soricidin

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4072851

Role of calpain in apoptosis.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4072851

Multidisciplinary management of small cell lung cancer

9 September 2017

1 reference

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Inhibition of cholinergic signaling causes apoptosis in human bronchioalveolar carcinoma

9 September 2017

1 reference

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Dietary phytochemicals and cancer prevention: Nrf2 signaling, epigenetics, and cell death mechanisms in blocking cancer initiation and progression.

9 September 2017

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Plants vs. cancer: a review on natural phytochemicals in preventing and treating cancers and their druggability

9 September 2017

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The role of the TRPV6 channel in cancer.

9 September 2017

1 reference

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Mechanisms in cancer-chemotherapeutic drugs-induced peripheral neuropathy

9 September 2017

1 reference

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TRP channels and cancer: new targets for diagnosis and chemotherapy

9 September 2017

1 reference

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Chemical and pharmacological aspects of capsaicin.

9 September 2017

1 reference

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Capsaicin displays anti-proliferative activity against human small cell lung cancer in cell culture and nude mice models via the E2F pathway

9 September 2017

1 reference

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Short-chain fatty acids induce intestinal transient receptor potential vanilloid type 6 expression in rats and Caco-2 cells

9 September 2017

1 reference

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Potential of spice-derived phytochemicals for cancer prevention.

9 September 2017

1 reference

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Activated cholinergic signaling provides a target in squamous cell lung carcinoma

9 September 2017

1 reference

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A small molecule disruptor of Rb/Raf-1 interaction inhibits cell proliferation, angiogenesis, and growth of human tumor xenografts in nude mice.

9 September 2017

1 reference

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Calciotropic and magnesiotropic TRP channels

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4072851

Peripheral TRPV1 receptors as targets for drug development: new molecules and mechanisms

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4072851

International Union of Pharmacology. XLIX. Nomenclature and structure-function relationships of transient receptor potential channels

9 September 2017

1 reference

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TRPV6 and prostate cancer: cancer growth beyond the prostate correlates with increased TRPV6 Ca2+ channel expression

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4072851

Ionomycin-activated calpain triggers apoptosis. A probable role for Bcl-2 family members.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4072851

G protein-coupled receptor signaling via Src kinase induces endogenous human transient receptor potential vanilloid type 6 (TRPV6) channel activation

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4072851

Calpain and caspase orchestrated death signal to accomplish apoptosis induced by resveratrol and its novel analog hydroxystilbene-1 [correction of hydroxstilbene-1] in cancer cells

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4072851

Capsaicin causes cell-cycle arrest and apoptosis in ER-positive and -negative breast cancer cells by modulating the EGFR/HER-2 pathway

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4072851

Capsaicin-induced apoptosis is regulated by endoplasmic reticulum stress- and calpain-mediated mitochondrial cell death pathways

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4072851

Capsaicin induces apoptosis and terminal differentiation in human glioma A172 cells

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4072851

The role of TRPV6 in breast carcinogenesis

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4072851

Capsaicin-induced apoptosis of glioma cells is mediated by TRPV1 vanilloid receptor and requires p38 MAPK activation.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4072851

TRPV6 mediates capsaicin-induced apoptosis in gastric cancer cells--Mechanisms behind a possible new "hot" cancer treatment

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4072851

Effects of orally administered capsaicin, the principal component of capsicum fruits, on the in vitro metabolism of the tobacco-specific nitrosamine NNK in hamster lung and liver microsomes.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4072851

TRPV1 inhibition attenuates IL-13 mediated asthma features in mice by reducing airway epithelial injury

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4072851

Triggering of transient receptor potential vanilloid type 1 (TRPV1) by capsaicin induces Fas/CD95-mediated apoptosis of urothelial cancer cells in an ATM-dependent manner

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4072851

The TRPV1 receptor is associated with preferential stress in large dorsal root ganglion neurons in early diabetic sensory neuropathy.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4072851

Stabilization of pulmonary mitochondrial enzyme system by capsaicin during benzo(a)pyrene induced experimental lung cancer.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4072851

CaT1 contributes to the stores-operated calcium current in Jurkat T-lymphocytes

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4072851

Modifying effects of dietary capsaicin and rotenone on 4-nitroquinoline 1-oxide-induced rat tongue carcinogenesis

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4072851

Vanilloid-mediated apoptosis in prostate cancer cells through a TRPV-1 dependent and a TRPV-1-independent mechanism

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4072851

Effects of capsaicin on chemically-induced two-stage mouse skin carcinogenesis

4 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24878626

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1007/S10495-014-1007-Y

1 reference

release_fspkon2xvvbqfnhyymz4jc7gcy

8 September 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/fspkon2xvvbqfnhyymz4jc7gcy

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference

8 September 2017

1 reference