The role of DNA methylation in cancer. (Q38138538)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:2404377%20AND%20SRC:MED&resulttype=core&format=json

28 September 2019

title

The role of DNA methylation in cancer (English)

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28 September 2019

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P A Jones

1

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28 September 2019

J D Buckley

series ordinal

2

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28 September 2019

publication date

1 January 1990

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Advances in Cancer Research

28 September 2019

published in

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28 September 2019

volume

54

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28 September 2019

page(s)

1-23

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publication type of scholarly work

28 September 2019

review article

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Reversibility of progression of the transformed phenotype in Ad5-transformed rat embryo cells

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Restriction sites containing CpG show a higher frequency of polymorphism in human DNA

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Genomic hypomethylation and far-5' sequence alterations are associated with carcinogen-induced activation of the hamster thymidine kinase gene

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Genomic footprinting reveals cell type-specific DNA binding of ubiquitous factors

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Methylation of single CpG dinucleotides within a promoter element of the Herpes simplex virus tk gene reduces its transcription in vivo

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The asymmetric methylation of CG palindromic dinucleotides increases sister-chromatid exchanges

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CpG-rich islands and the function of DNA methylation

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A fraction of the mouse genome that is derived from islands of nonmethylated, CpG-rich DNA

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A specific mismatch repair event protects mammalian cells from loss of 5-methylcytosine

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Chromatin structure is required to block transcription of the methylated herpes simplex virus thymidine kinase gene

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DNA methylation and the regulation of globin gene expression

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The tumorigenicity of 5-azacytidine in the male Fischer rat.

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DNA methylation and gene activity

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7 January 2021

Allele-specific methylation of the human c-Ha-ras-1 gene

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Cell lineage-specific undermethylation of mouse repetitive DNA

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Functional striated muscle cells from non-myoblast precursors following 5-azacytidine treatment

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The short arm of chromosome 11 is a "hot spot" for hypermethylation in human neoplasia

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7 January 2021

5-azacytidine potentiates initiation induced by carcinogens in rat liver

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7 January 2021

DNA methylation and gene activity

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7 January 2021

Inactivation of mammalian DNA methylase activities by N-methyl-N′-nitro-N-nitrosoguanidine

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7 January 2021

Isolation of transcription factors that discriminate between different promoters recognized by RNA polymerase II

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7 January 2021

Ethylation of poly(dC-dG).poly(dC-dG) by ethyl methanesulfonate stimulates the activity of mammalian DNA methyltransferase in vitro

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7 January 2021

Hypomethylation of ras oncogenes in primary human cancers

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7 January 2021

Hypomethylation distinguishes genes of some human cancers from their normal counterparts

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7 January 2021

On a possible epigenetic mechanism(s) of tumor cell heterogeneity. The role of DNA methylation

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7 January 2021

Selection of strongly immunogenic "tum-" variants from tumors at high frequency using 5-azacytidine

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7 January 2021

Genetic analysis of tumerigenesis: XVI. Chromosome changes in azacytidine- and insulin-induced tumorigenesis

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7 January 2021

The 5-methylcytosine content of DNA from human tumors

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7 January 2021

CpG islands in vertebrate genomes

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7 January 2021

Hypomethylation of DNA from benign and malignant human colon neoplasms

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7 January 2021

Chromatin structure and de novo methylation of sperm DNA: implications for activation of the paternal genome

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7 January 2021

Cytosine methylation does not affect binding of transcription factor Sp1

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7 January 2021

Azacytidine-induced tumorigenesis of CHEF/18 cells: correlated DNA methylation and chromosome changes

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7 January 2021

Structure and tissue-specific expression of the human metallothionein IB gene

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7 January 2021

Specific factors binding to the late E2A promoter region of adenovirus type 2 DNA: no apparent effects of 5'-CCGG-3' methylation

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7 January 2021

Sp1 transcription factor binds DNA and activates transcription even when the binding site is CpG methylated

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7 January 2021

A new theory of carcinogenesis

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7 January 2021

Chemistry. How are alkynes scrambled?

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7 January 2021

A protein from human placental nuclei binds preferentially to 5-methylcytosine-rich DNA

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7 January 2021

Induction of prolactin-deficient variants of GH3 rat pituitary tumor cells by ethyl methanesulfonate: reversion by 5-azacytidine, a DNA methylation inhibitor

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7 January 2021

Activation of a nonexpressed hypoxanthine phosphoribosyltransferase allele in mutant H23 HeLa cells by agents that inhibit DNA methylation

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7 January 2021

Altering gene expression with 5-azacytidine

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7 January 2021

Active X chromosome DNA is unmethylated at eight CCGG sites clustered in a guanine-plus-cytosine-rich island at the 5' end of the gene for phosphoglycerate kinase

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7 January 2021

DNA methylation affects the formation of active chromatin

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7 January 2021

The approaching era of the tumor suppressor genes

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Mutation and cancer: statistical study of retinoblastoma

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Methylation of deoxycytidine in replicating cells treated with ultraviolet radiation and chemical carcinogens

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Expression of the chloramphenicol acetyltransferase gene in mammalian cells under the control of adenovirus type 12 promoters: effect of promoter methylation on gene expression

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Genetic studies on hydatidiform moles II. The origin of complete moles

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7 January 2021

Ultraviolet radiation-induced metallothionein-I gene activation is associated with extensive DNA demethylation

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7 January 2021

Methylation of the mouse hprt gene differs on the active and inactive X chromosomes

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7 January 2021

Methylation of the Hprt gene on the inactive X occurs after chromosome inactivation

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7 January 2021

Chemical carcinogens induce cadmium resistance and activate metallothionein genes in cadmium sensitive S49 mouse cells

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7 January 2021

Hypomethylation of host cell DNA synthesized after infection or transformation of cells by herpes simplex virus

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7 January 2021

In vitro methylation of specific regions of the cloned Moloney sarcoma virus genome inhibits its transforming activity

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7 January 2021

Enhancement of experimental metastasis by pretreatment of tumour cells with hydroxyurea

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7 January 2021

Memories of mother and father

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7 January 2021

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7 January 2021

Variable effects of DNA-synthesis inhibitors upon DNA methylation in mammalian cells

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7 January 2021

Induction of the metastatic phenotype in a mouse tumor model by 5-azacytidine, and characterization of an antigen associated with metastatic activity

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7 January 2021

Modulatory effects of 5-azacytidine, phorbol ester, and retinoic acid on the malignant phenotype of human lung cancer cells

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7 January 2021

Treatment of human cell lines with 5-azacytidine may result in profound alterations in clonogenicity and growth rate

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7 January 2021

Mismatch repair in Escherichia coli

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7 January 2021

Capture and characterization of 5-aza-2'-deoxycytidine-treated C3H/10T1/2 cells prior to transformation

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7 January 2021

DNA methylation patterns. Formation and function

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7 January 2021

Loss of a Harvey ras allele in sporadic Wilms' tumour

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7 January 2021

Genomic imprinting determines methylation of parental alleles in transgenic mice

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7 January 2021

X inactivation, differentiation, and DNA methylation

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7 January 2021

5-Methylcytosine, Gene Regulation, and Cancer

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7 January 2021

Undermethylation of structural gene sequences in extraembryonic lineages of the mouse

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7 January 2021

Interferon-induced revertants of ras-transformed cells: resistance to transformation by specific oncogenes and retransformation by 5-azacytidine

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7 January 2021

Differences in DNA methylation during oogenesis and spermatogenesis and their persistence during early embryogenesis in the mouse

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7 January 2021

Degree of methylation of transgenes is dependent on gamete of origin

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7 January 2021

A direct demonstration of somatically paired heterochromatin of human chromosomes

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Cell specificity and an effect of ras on human metallothionein gene expression

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7 January 2021

Interclonal variation in methylation patterns for expressed and non-expressed genes.

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7 January 2021

Experimental reconstruction of mouse eggs and embryos: an analysis of mammalian development

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7 January 2021

Parental legacy determines methylation and expression of an autosomal transgene: a molecular mechanism for parental imprinting

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7 January 2021

CG dinucleotide clusters in MHC genes and in 5' demethylated genes

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7 January 2021

Expression of a cloned adenovirus gene is inhibited by in vitro methylation

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7 January 2021

Genetic alterations during colorectal-tumor development

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7 January 2021

A human DNA-binding protein is methylation-specific and sequence-specific

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7 January 2021

Methylated DNA-binding protein from human placenta recognizes specific methylated sites on several prokaryotic DNAs

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7 January 2021

Cytosine methylation prevents binding to DNA of a HeLa cell transcription factor required for optimal expression of the adenovirus major late promoter

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7 January 2021

DNA methylation decreases in aging but not in immortal cells

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7 January 2021

Chemical carcinogen-induced decreases in genomic 5-methyldeoxycytidine content of normal human bronchial epithelial cells

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7 January 2021

Clusters of CpG dinucleotides implicated by nuclease hypersensitivity as control elements of housekeeping genes

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Developmental regulation of two 5S ribosomal RNA genes

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7 January 2021

Effect of in vitro DNA methylation on beta-globin gene expression

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7 January 2021

10.1016/S0065-230X(08)60806-4

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