Functional avidity: a measure to predict the efficacy of effector T cells? (Q38066211)

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20 February 2020

review article

1 reference

title

Functional avidity: a measure to predict the efficacy of effector T cells? (English)

1 reference

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20 February 2020

main subject

cell surface receptor

1 reference

31 July 2019

1 reference

4 August 2019

1 reference

12 October 2019

hemic and immune systems

1 reference

18 October 2019

1 reference

15 December 2019

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23227083%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

Alexandre Harari

6

1 reference

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20 February 2020

4

Giuseppe Pantaleo

1 reference

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20 February 2020

author name string

Selena Viganò

1

1 reference

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20 February 2020

Matthieu Perreau

3

1 reference

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20 February 2020

Dietmar Zehn

5

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20 February 2020

publication date

20 November 2012

6 references

31 July 2019

4 August 2019

12 October 2019

18 October 2019

15 December 2019

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23227083%20AND%20SRC:MED&resulttype=core&format=json

Clinical and Developmental Immunology

20 February 2020

published in

6 references

31 July 2019

4 August 2019

12 October 2019

18 October 2019

15 December 2019

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23227083%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

volume

2012

1 reference

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20 February 2020

page(s)

153863

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Creative Commons Attribution 3.0 Unported

20 February 2020

copyright license

5 references

31 July 2019

4 August 2019

12 October 2019

18 October 2019

TCR clonotypes modulate the protective effect of HLA class I molecules in HIV-1 infection

15 December 2019

0 references

1 reference

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Epitope targeting and viral inoculum are determinants of Nef-mediated immune evasion of HIV-1 from cytotoxic T lymphocytes

6 September 2017

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Mechanisms behind functional avidity maturation in T cells

6 September 2017

1 reference

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Immunotherapy of cancer in 2012.

6 September 2017

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TCR signaling requirements for activating T cells and for generating memory

6 September 2017

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CTL responses of high functional avidity and broad variant cross-reactivity are associated with HIV control

6 September 2017

1 reference

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Clonotype and repertoire changes drive the functional improvement of HIV-specific CD8 T cell populations under conditions of limited antigenic stimulation

6 September 2017

1 reference

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Enhanced cytotoxicity and decreased CD8 dependence of human cancer-specific cytotoxic T lymphocytes after vaccination with low peptide dose.

6 September 2017

1 reference

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CD8+ T-cell cross-competition is governed by peptide-MHC class I stability

6 September 2017

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CD8(+) T cells: foot soldiers of the immune system

6 September 2017

1 reference

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Major histocompatibility complex-dependent cytotoxic T lymphocyte repertoire and functional avidity contribute to strain-specific disease susceptibility after murine respiratory syncytial virus infection

6 September 2017

1 reference

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A new pathway of CD5 glycoprotein-mediated T cell inhibition dependent on inhibitory phosphorylation of Fyn kinase.

6 September 2017

1 reference

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High-functional-avidity cytotoxic T lymphocyte responses to HLA-B-restricted Gag-derived epitopes associated with relative HIV control

6 September 2017

1 reference

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Escape from highly effective public CD8+ T-cell clonotypes by HIV

6 September 2017

1 reference

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The immunological synapse: a cause or consequence of T-cell receptor triggering?

6 September 2017

1 reference

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Virological and immunological factors associated with HIV-1 differential disease progression in HLA-B 58:01-positive individuals

6 September 2017

1 reference

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High-avidity, high-IFNγ-producing CD8 T-cell responses following immune selection during HIV-1 infection

6 September 2017

1 reference

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Increased HIV-specific CD8+ T-cell cytotoxic potential in HIV elite controllers is associated with T-bet expression

6 September 2017

1 reference

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The major genetic determinants of HIV-1 control affect HLA class I peptide presentation

6 September 2017

1 reference

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Efficacious early antiviral activity of HIV Gag- and Pol-specific HLA-B 2705-restricted CD8+ T cells

6 September 2017

1 reference

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Perforin expression directly ex vivo by HIV-specific CD8 T-cells is a correlate of HIV elite control

6 September 2017

1 reference

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Effects of thymic selection of the T-cell repertoire on HLA class I-associated control of HIV infection

6 September 2017

1 reference

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The kinetics of two-dimensional TCR and pMHC interactions determine T-cell responsiveness.

6 September 2017

1 reference

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Genital and oral mucosal immune response against HIV-1 in exposed uninfected individuals

6 September 2017

1 reference

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An endogenous positively selecting peptide enhances mature T cell responses and becomes an autoantigen in the absence of microRNA miR-181a

6 September 2017

1 reference

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HIV reservoir size and persistence are driven by T cell survival and homeostatic proliferation

6 September 2017

1 reference

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Dynamic regulation of T-cell costimulation through TCR-CD28 microclusters

6 September 2017

1 reference

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Tumor antigen-specific CD8 T cells infiltrating the tumor express high levels of PD-1 and are functionally impaired

6 September 2017

1 reference

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Antigen sensitivity is a major determinant of CD8+ T-cell polyfunctionality and HIV-suppressive activity

6 September 2017

1 reference

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Phenotype and function of protective T cell immune responses in HIV.

6 September 2017

1 reference

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HLA-associated viral mutations are common in human immunodeficiency virus type 1 elite controllers

6 September 2017

1 reference

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T-cell receptor binding affinities and kinetics: impact on T-cell activity and specificity

6 September 2017

1 reference

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Coregulation of CD8+ T cell exhaustion by multiple inhibitory receptors during chronic viral infection.

6 September 2017

1 reference

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Tailoring T-cell receptor signals by proximal negative feedback mechanisms

6 September 2017

1 reference

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Avidity maturation of memory CD8 T cells is limited by self-antigen expression

6 September 2017

1 reference

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Genetic and immunologic heterogeneity among persons who control HIV infection in the absence of therapy.

6 September 2017

1 reference

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Detuning CD8 T cells: down-regulation of CD8 expression, tetramer binding, and response during CTL activation

6 September 2017

1 reference

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A constant affinity threshold for T cell tolerance

6 September 2017

1 reference

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Skewed association of polyfunctional antigen-specific CD8 T cell populations with HLA-B genotype

6 September 2017

1 reference

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Superior control of HIV-1 replication by CD8+ T cells is reflected by their avidity, polyfunctionality, and clonal turnover

6 September 2017

1 reference

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Mobilizing the low-avidity T cell repertoire to kill tumors

6 September 2017

1 reference

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A whole-genome association study of major determinants for host control of HIV-1

6 September 2017

1 reference

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Adoptive T cell therapy for cancer in the clinic

6 September 2017

1 reference

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Availability of a diversely avid CD8+ T cell repertoire specific for the subdominant HLA-A2-restricted HIV-1 Gag p2419-27 epitope

6 September 2017

1 reference

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Competition for antigen determines the stability of T cell-dendritic cell interactions during clonal expansion.

6 September 2017

1 reference

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The function of programmed cell death 1 and its ligands in regulating autoimmunity and infection

6 September 2017

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Selective depletion of high-avidity human immunodeficiency virus type 1 (HIV-1)-specific CD8+ T cells after early HIV-1 infection

6 September 2017

1 reference

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Functional and biophysical characterization of an HLA-A*6801-restricted HIV-specific T cell receptor

6 September 2017

1 reference

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New insights into the molecular mechanisms of store-operated Ca2+ signaling in T cells

6 September 2017

1 reference

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PD-1 Expression in Acute Hepatitis C Virus (HCV) Infection Is Associated with HCV-Specific CD8 Exhaustion

6 September 2017

1 reference

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PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression

6 September 2017

1 reference

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T cells with low avidity for a tissue-restricted antigen routinely evade central and peripheral tolerance and cause autoimmunity

6 September 2017

1 reference

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Functional signatures of protective antiviral T-cell immunity in human virus infections.

6 September 2017

1 reference

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Maintenance of viral suppression in HIV-1-infected HLA-B*57+ elite suppressors despite CTL escape mutations

6 September 2017

1 reference

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Impact of vaccine-induced mucosal high-avidity CD8+ CTLs in delay of AIDS viral dissemination from mucosa

6 September 2017

1 reference

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Avidity for antigen shapes clonal dominance in CD8+ T cell populations specific for persistent DNA viruses

6 September 2017

1 reference

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Vaccines with enhanced costimulation maintain high avidity memory CTL.

6 September 2017

1 reference

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Coexistence of multivalent and monovalent TCRs explains high sensitivity and wide range of response

6 September 2017

1 reference

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Multiple costimulatory modalities enhance CTL avidity

6 September 2017

1 reference

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Cytomegalovirus (CMV)-specific cellular immune responses.

6 September 2017

1 reference

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Molecular mechanisms and biological significance of CTL avidity

6 September 2017

1 reference

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Persistent recognition of autologous virus by high-avidity CD8 T cells in chronic, progressive human immunodeficiency virus type 1 infection.

6 September 2017

1 reference

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The differential ability of HLA B*5701+ long-term nonprogressors and progressors to restrict human immunodeficiency virus replication is not caused by loss of recognition of autologous viral gag sequences

6 September 2017

1 reference

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Viral persistence alters CD8 T-cell immunodominance and tissue distribution and results in distinct stages of functional impairment

6 September 2017

1 reference

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Antigen density presented by dendritic cells in vivo differentially affects the number and avidity of primary, memory, and recall CD8+ T cells.

6 September 2017

1 reference

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The influence of HLA genotype on AIDS

6 September 2017

1 reference

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Self-recognition promotes the foreign antigen sensitivity of naive T lymphocytes

6 September 2017

1 reference

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Epistatic interaction between KIR3DS1 and HLA-B delays the progression to AIDS

6 September 2017

1 reference

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Selection and fine-tuning of the autoimmune T-cell repertoire

6 September 2017

1 reference

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Treatment of primary HIV-1 infection with cyclosporin A coupled with highly active antiretroviral therapy

6 September 2017

1 reference

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Interactions between MHC molecules and co-receptors of the TCR.

6 September 2017

1 reference

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CD8(-) T cell transfectants that express a high affinity T cell receptor exhibit enhanced peptide-dependent activation.

6 September 2017

1 reference

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Increased TCR avidity after T cell activation: a mechanism for sensing low-density antigen

6 September 2017

1 reference

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Negative selection during the peripheral immune response to antigen

6 September 2017

1 reference

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HLA B*5701 is highly associated with restriction of virus replication in a subgroup of HIV-infected long term nonprogressors

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3511839

Critical role for CD8 in T cell receptor binding and activation by peptide/major histocompatibility complex multimers

6 September 2017

1 reference

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An inverse relationship between T cell receptor affinity and antigen dose during CD4(+) T cell responses in vivo and in vitro

6 September 2017

1 reference

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Dramatic rise in plasma viremia after CD8(+) T cell depletion in simian immunodeficiency virus-infected macaques.

6 September 2017

1 reference

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T cell affinity maturation by selective expansion during infection

6 September 2017

1 reference

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Control of viremia in simian immunodeficiency virus infection by CD8+ lymphocytes

6 September 2017

1 reference

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CD5 expression is developmentally regulated by T cell receptor (TCR) signals and TCR avidity

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3511839

Preselection thymocytes are more sensitive to T cell receptor stimulation than mature T cells

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3511839

Functional management of an antiviral cytotoxic T-cell response

6 September 2017

1 reference

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Resting memory CD8+ T cells are hyperreactive to antigenic challenge in vitro

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3511839

Selective expansion of high- or low-avidity cytotoxic T lymphocytes and efficacy for adoptive immunotherapy.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3511839

Temporal association of cellular immune responses with the initial control of viremia in primary human immunodeficiency virus type 1 syndrome

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3511839

Virus-specific CD8+ cytotoxic T-lymphocyte activity associated with control of viremia in primary human immunodeficiency virus type 1 infection

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3511839

Kinetics of T-cell receptor binding to peptide/I-Ek complexes: correlation of the dissociation rate with T-cell responsiveness

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3511839

Kinetic proofreading in T-cell receptor signal transduction

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3511839

CD8 beta chain influences CD8 alpha chain-associated Lck kinase activity

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3511839

Epitope-dependent avidity thresholds for cytotoxic T-lymphocyte clearance of virus-infected cells

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3511839

Thymic selection threshold defined by compartmentalization of Ras/MAPK signalling

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3511839

Immunological unresponsiveness characterized by increased expression of CD5 on peripheral T cells induced by dendritic cells in vivo

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3511839

Extended presentation of specific MHC-peptide complexes by mature dendritic cells compared to other types of antigen-presenting cells.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3511839

High avidity antigen-specific CTL identified by CD8-independent tetramer staining

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3511839

Peptide requirement for CTL activation reflects the sensitivity to CD3 engagement: correlation with CD8alphabeta versus CD8alphaalpha expression

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3511839

High-avidity CTL exploit two complementary mechanisms to provide better protection against viral infection than low-avidity CTL.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3511839

MHC-peptide ligand interactions establish a functional threshold for antigen-specific T cell recognition

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3511839

Isolation of high avidity melanoma-reactive CTL from heterogeneous populations using peptide-MHC tetramers.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3511839

High avidity CTLs for two self-antigens demonstrate superior in vitro and in vivo antitumor efficacy.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3511839

The p56lck SH2 domain mediates recruitment of CD8/p56lck to the activated T cell receptor/CD3/zeta complex.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3511839

T cell activation determined by T cell receptor number and tunable thresholds.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3511839

The life span of major histocompatibility complex-peptide complexes influences the efficiency of presentation and immunogenicity of two class I-restricted cytotoxic T lymphocyte epitopes in the Epstein-Barr virus nuclear antigen 4

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3511839

T-cell-receptor affinity and thymocyte positive selection

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3511839

Enhanced immunogenicity of CTL antigens through mutation of the CD8 binding MHC class I invariant region

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3511839

Dominant clonotypes within HIV-specific T cell responses are programmed death-1high and CD127low and display reduced variant cross-reactivity.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3511839

Complete but curtailed T-cell response to very low-affinity antigen

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3511839

Potentially exposed but uninfected individuals produce cytotoxic and polyfunctional human immunodeficiency virus type 1-specific CD8(+) T-cell responses which can be defined to the epitope level

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3511839

Molecular signature of CD8+ T cell exhaustion during chronic viral infection.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3511839

A kinetic basis for T cell receptor repertoire selection during an immune response

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3511839

CD3 antigen-mediated calcium signals and protein kinase C activation are higher in CD45R0+ than in CD45RA+ human T lymphocyte subsets

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3511839

A kinase-independent function of Lck in potentiating antigen-specific T cell activation

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3511839

Advantage of higher-avidity CTL specific for Tax against human T-lymphotropic virus-1 infected cells and tumors

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3511839

The costimulatory molecule CD27 maintains clonally diverse CD8(+) T cell responses of low antigen affinity to protect against viral variants.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3511839

Large TCR diversity of virus-specific CD8 T cells provides the mechanistic basis for massive TCR renewal after antigen exposure

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3511839

Increased sensitivity to antigen in high avidity CD8(+) T cells results from augmented membrane proximal T-cell receptor signal transduction

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3511839

Persistent viral infection in humans can drive high frequency low-affinity T-cell expansions.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3511839

Induction of systemic HIV-1-specific cellular immune responses by oral exposure in the uninfected partner of discordant couples

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3511839

Rapid CD8+ T cell repertoire focusing and selection of high-affinity clones into memory following primary infection with a persistent human virus: human cytomegalovirus

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3511839

A correlation between function and selected measures of T cell avidity in influenza virus-specific CD8+ T cell responses

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3511839

Differential selection pressure exerted on HIV by CTL targeting identical epitopes but restricted by distinct HLA alleles from the same HLA supertype.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3511839

Accumulation of low-avidity anti-melanocortin receptor 1 (anti-MC1R) CD8+ T cells in the lesional skin of a patient with melanoma-related depigmentation.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3511839

Dominant influence of HLA-B in mediating the potential co-evolution of HIV and HLA.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3511839

Functionally impaired HIV-specific CD8 T cells show high affinity TCR-ligand interactions.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3511839

T cell avidity determines the level of CTL activation

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3511839

The functional profile of primary human antiviral CD8+ T cell effector activity is dictated by cognate peptide concentration.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3511839

Selective induction of high avidity CTL by altering the balance of signals from APC.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3511839

Direct link between mhc polymorphism, T cell avidity, and diversity in immune defense

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3511839

Acute phase cytotoxic T lymphocyte escape is a hallmark of simian immunodeficiency virus infection

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3511839

A novel approach to the analysis of specificity, clonality, and frequency of HIV-specific T cell responses reveals a potential mechanism for control of viral escape.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3511839

How much TCR does a T cell need?

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3511839

CD8+ memory T cells (CD44high, Ly-6C+) are more sensitive than naive cells to (CD44low, Ly-6C-) to TCR/CD8 signaling in response to antigen.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3511839

Different responses are elicited in cytotoxic T lymphocytes by different levels of T cell receptor occupancy.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3511839

Naive versus memory CD4 T cell response to antigen. Memory cells are less dependent on accessory cell costimulation and can respond to many antigen-presenting cell types including resting B cells.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3511839

Down-regulation of T cell receptors on self-reactive T cells as a novel mechanism for extrathymic tolerance induction.

31 August 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F153863

CD8+ T-cell responses to different HIV proteins have discordant associations with viral load

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F153863

Different T Cell Receptor Affinity Thresholds and CD8 Coreceptor Dependence Govern Cytotoxic T Lymphocyte Activation and Tetramer Binding Properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F153863

Treatment of primary HIV-1 infection with cyclosporin A coupled with highly active antiretroviral therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F153863

Lower receptor avidity required for thymic clonal deletion than for effector T-cell function

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F153863

Differential role and tissue specificity of interleukin-1α gene expression in atherogenesis and lipid metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F153863

Adjuvant Combination and Antigen Targeting as a Strategy to Induce Polyfunctional and High-Avidity T-Cell Responses against Poorly Immunogenic Tumors

21 January 2018

1 reference

12 December 2020

Human CD45RA+ and CD45R0+ T cells exhibit similar CD3/T cell receptor-mediated transmembrane signaling capacities but differ in response to co-stimulatory signals

1 reference

12 December 2020

T cell priming by dendritic cells: thresholds for proliferation, differentiation and death and intraclonal functional diversification

1 reference

12 December 2020

Relative contribution of HIV-specific functional lymphocyte subsets restricted by protective and non-protective HLA alleles

1 reference

12 December 2020

Peripheral expression of self-MHC-II influences the reactivity and self-tolerance of mature CD4(+) T cells: evidence from a lymphopenic T cell model

1 reference

12 December 2020

Evidence of HIV-1 adaptation to HLA-restricted immune responses at a population level

1 reference

12 December 2020

Localization, quantitation, and in situ detection of specific peptide-MHC class I complexes using a monoclonal antibody

1 reference

12 December 2020

Activation of low avidity CTL specific for a self epitope results in tumor rejection but not autoimmunity

1 reference

12 December 2020

Precursor frequency can compensate for lower TCR expression in T cell competition during priming in vivo

1 reference

12 December 2020

Functional avidity maturation of CD8(+) T cells without selection of higher affinity TCR

1 reference

12 December 2020

HIV-specific CD8+ T cell proliferation is coupled to perforin expression and is maintained in nonprogressors

1 reference

12 December 2020

Orally exposed uninfected individuals have systemic anti-HIV responses associating with partnersʼ viral load

1 reference

12 December 2020

Quantitative analysis of the contribution of TCR/pepMHC affinity and CD8 to T cell activation

1 reference

12 December 2020

Heterogeneous T-cell response to MAGE-A10(254-262): high avidity-specific cytolytic T lymphocytes show superior antitumor activity

1 reference

12 December 2020

CD8+ T cell activation is governed by TCR-peptide/MHC affinity, not dissociation rate

1 reference

12 December 2020

TCR binding kinetics measured with MHC class I tetramers reveal a positive selecting peptide with relatively high affinity for TCR

1 reference

12 December 2020

https://api.fatcat.wiki/v0/release/twvyfqqwlfcbbafrv5owe6xvmy

Identifiers

1 reference

30 July 2022

release_twvyfqqwlfcbbafrv5owe6xvmy

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/twvyfqqwlfcbbafrv5owe6xvmy

30 July 2022

https://api.fatcat.wiki/v0/release/twvyfqqwlfcbbafrv5owe6xvmy

1 reference

30 July 2022

https://api.fatcat.wiki/v0/release/twvyfqqwlfcbbafrv5owe6xvmy

1 reference

30 July 2022