AID: a riddle wrapped in a mystery inside an enigma (Q37815430)

23 August 2017

1 reference

title

AID: a riddle wrapped in a mystery inside an enigma (English)

1 reference

23 August 2017

3

0 references

author name string

Dana C Upton

series ordinal

1

1 reference

23 August 2017

Briana L Gregory

series ordinal

2

1 reference

23 August 2017

Shyam Unniraman

series ordinal

4

1 reference

23 August 2017

publication date

1 April 2011

1 reference

23 August 2017

1 reference

23 August 2017

volume

49

1 reference

23 August 2017

issue

1-3

1 reference

23 August 2017

page(s)

14-24

1 reference

Evolutionary and somatic selection of the antibody repertoire in the mouse.

23 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1007%2FS12026-010-8190-X

Mechanism and regulation of class switch recombination

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-010-8190-X

The biochemistry of somatic hypermutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-010-8190-X

Immunoglobulin somatic hypermutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-010-8190-X

Molecular mechanisms of antibody somatic hypermutation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-010-8190-X

A coming-of-age story: activation-induced cytidine deaminase turns 10.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-010-8190-X

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-010-8190-X

Specific expression of activation-induced cytidine deaminase (AID), a novel member of the RNA-editing deaminase family in germinal center B cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-010-8190-X

Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-010-8190-X

Activation-induced cytidine deaminase (AID) deficiency causes the autosomal recessive form of the Hyper-IgM syndrome (HIGM2)

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-010-8190-X

hUNG2 is the major repair enzyme for removal of uracil from U:A matches, U:G mismatches, and U in single-stranded DNA, with hSMUG1 as a broad specificity backup

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-010-8190-X

Uracil in DNA and its processing by different DNA glycosylases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-010-8190-X

High-fidelity correction of genomic uracil by human mismatch repair activities

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-010-8190-X

Hypermutation at A/T sites during G.U mismatch repair in vitro by human B-cell lysates

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-010-8190-X

DNA polymerases in adaptive immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-010-8190-X

The MRE11-RAD50-NBS1 complex accelerates somatic hypermutation and gene conversion of immunoglobulin variable regions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-010-8190-X

Processive AID-catalysed cytosine deamination on single-stranded DNA simulates somatic hypermutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-010-8190-X

The concerted action of Msh2 and UNG stimulates somatic hypermutation at A . T base pairs

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-010-8190-X

Pol zeta ablation in B cells impairs the germinal center reaction, class switch recombination, DNA break repair, and genome stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-010-8190-X

Hijacked DNA repair proteins and unchained DNA polymerases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-010-8190-X

Role for DNA repair factor XRCC4 in immunoglobulin class switch recombination.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-010-8190-X

IgH class switching and translocations use a robust non-classical end-joining pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-010-8190-X

Activation-induced cytidine deaminase deaminates deoxycytidine on single-stranded DNA but requires the action of RNase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-010-8190-X

Activation-induced cytidine deaminase (AID) can target both DNA strands when the DNA is supercoiled

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-010-8190-X

AID mediates hypermutation by deaminating single stranded DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-010-8190-X

Transcription-targeted DNA deamination by the AID antibody diversification enzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-010-8190-X

The transcription elongation complex directs activation-induced cytidine deaminase-mediated DNA deamination

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-010-8190-X

The activation-induced cytidine deaminase (AID) efficiently targets DNA in nucleosomes but only during transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-010-8190-X

Transcription enhances AID-mediated cytidine deamination by exposing single-stranded DNA on the nontemplate strand

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-010-8190-X

AID enzyme-induced hypermutation in an actively transcribed gene in fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-010-8190-X

Somatic hypermutation of the AID transgene in B and non-B cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-010-8190-X

Constitutive expression of AID leads to tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-010-8190-X

R-loops at immunoglobulin class switch regions in the chromosomes of stimulated B cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-010-8190-X

Downstream boundary of chromosomal R-loops at murine switch regions: implications for the mechanism of class switch recombination

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-010-8190-X

Sequence dependence of chromosomal R-loops at the immunoglobulin heavy-chain Smu class switch region

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-010-8190-X

Replication protein A interacts with AID to promote deamination of somatic hypermutation targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-010-8190-X

Boundaries of somatic mutation in rearranged immunoglobulin genes: 5' boundary is near the promoter, and 3' boundary is approximately 1 kb from V(D)J gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-010-8190-X

The very 5' end and the constant region of Ig genes are spared from somatic mutation because AID does not access these regions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-010-8190-X

The intrinsic hypermutability of antibody heavy and light chain genes decays exponentially

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-010-8190-X

Transcription-coupled events associating with immunoglobulin switch region chromatin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-010-8190-X

E2A expression stimulates Ig hypermutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-010-8190-X

Two levels of protection for the B cell genome during somatic hypermutation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-010-8190-X

14-3-3 adaptor proteins recruit AID to 5'-AGCT-3'-rich switch regions for class switch recombination.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-010-8190-X

Activation-induced cytidine deaminase targets DNA at sites of RNA polymerase II stalling by interaction with Spt5

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-010-8190-X

Cutting edge: a cis-acting DNA element targets AID-mediated sequence diversification to the chicken Ig light chain gene locus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-010-8190-X

A cis-acting diversification activator both necessary and sufficient for AID-mediated hypermutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-010-8190-X

Switch recombination and somatic hypermutation are controlled by the heavy chain 3' enhancer region

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-010-8190-X

AID and Igh switch region-Myc chromosomal translocations

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-010-8190-X

Cellular origin of human B-cell lymphomas.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-010-8190-X

Balancing AID and DNA repair during somatic hypermutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-010-8190-X

Widespread genomic breaks generated by activation-induced cytidine deaminase are prevented by homologous recombination

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-010-8190-X

CpG islands--'a rough guide'.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-010-8190-X

DNA methylation profiling of human chromosomes 6, 20 and 22

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-010-8190-X

Chromosome-wide and promoter-specific analyses identify sites of differential DNA methylation in normal and transformed human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-010-8190-X

Initial sequencing and analysis of the human genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-010-8190-X

Unmethylated domains in vertebrate DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-010-8190-X

A genome-wide analysis of CpG dinucleotides in the human genome distinguishes two distinct classes of promoters

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-010-8190-X

The colorful history of active DNA demethylation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-010-8190-X

Active DNA demethylation: many roads lead to Rome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-010-8190-X

Modulation of plasmid DNA methylation and expression in zebrafish embryos

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-010-8190-X

Activation-induced cytidine deaminase deaminates 5-methylcytosine in DNA and is expressed in pluripotent tissues: implications for epigenetic reprogramming

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-010-8190-X

DNA demethylation in zebrafish involves the coupling of a deaminase, a glycosylase, and gadd45.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-010-8190-X

Conserved DNA methylation in Gadd45a(-/-) mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-010-8190-X

Enhanced CpG mutability and tumorigenesis in MBD4-deficient mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-010-8190-X

Reprogramming towards pluripotency requires AID-dependent DNA demethylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-010-8190-X

Genome-wide erasure of DNA methylation in mouse primordial germ cells is affected by AID deficiency.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-010-8190-X

Genome-wide reprogramming in the mouse germ line entails the base excision repair pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-010-8190-X

Nuclear reprogramming to a pluripotent state by three approaches

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-010-8190-X

Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-010-8190-X

Origin of Antibody Variation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-010-8190-X

Somatic hypermutation of immunoglobulin genes is linked to transcription initiation

21 January 2018

1 reference

12 December 2020

Strand-biased spreading of mutations during somatic hypermutation

1 reference

12 December 2020

A fraction of the mouse genome that is derived from islands of nonmethylated, CpG-rich DNA

1 reference

12 December 2020

The E box motif CAGGTG enhances somatic hypermutation without enhancing transcription

1 reference

12 December 2020

10.1007/S12026-010-8190-X

Identifiers

DOI

1 reference

release_askmaal4gjedncmzhywx47cq7a

23 August 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/askmaal4gjedncmzhywx47cq7a

24 November 2022

mapped directly with Wikidata item

1 reference