Natural evolution of TEM-1 β-lactamase: experimental reconstruction and clinical relevance (Q37735903)

22 August 2017

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title

Natural evolution of TEM-1 β-lactamase: experimental reconstruction and clinical relevance (English)

1 reference

22 August 2017

Merijn L M Salverda

1

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PubMed ID

20412308

22 August 2017

J Arjan G M De Visser

series ordinal

2

1 reference

PubMed ID

20412308

22 August 2017

Miriam Barlow

series ordinal

3

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22 August 2017

1 November 2010

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FEMS Microbiology Reviews

22 August 2017

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22 August 2017

34

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22 August 2017

1015-1036

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22 August 2017

6

1 reference

A standard numbering scheme for the class A beta-lactamases

22 August 2017

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2010.00222.X

Novel, plasmid-encoded, TEM-derived extended-spectrum beta-lactamase in Klebsiella pneumoniae conferring higher resistance to aztreonam than to extended-spectrum cephalosporins

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2010.00222.X

Nationwide survey of extended-spectrum {beta}-lactamase-producing Enterobacteriaceae in the French community setting

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2010.00222.X

Expanded molecular diversity generation during directed evolution by trinucleotide exchange (TriNEx).

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2010.00222.X

Evidence for recombination among the alleles encoding TEM and SHV beta-lactamases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2010.00222.X

Ohno's model revisited: measuring the frequency of potentially adaptive mutations under various mutational drifts

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2010.00222.X

Intense neutral drifts yield robust and evolvable consensus proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2010.00222.X

Single amino acid replacements at positions altered in naturally occurring extended-spectrum TEM beta-lactamases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2010.00222.X

Selection of naturally occurring extended-spectrum TEM beta-lactamase variants by fluctuating beta-lactam pressure.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2010.00222.X

Thermodynamic prediction of protein neutrality

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2010.00222.X

Development of test panel of beta-lactamases expressed in a common Escherichia coli host background for evaluation of new beta-lactam antibiotics

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2010.00222.X

Incidence of class A extended-spectrum beta-lactamases in Champagne-Ardenne (France): a 1 year prospective study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2010.00222.X

Targeted gene evolution in Escherichia coli using a highly error-prone DNA polymerase I.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2010.00222.X

Selection and characterization of amino acid substitutions at residues 237-240 of TEM-1 beta-lactamase with altered substrate specificity for aztreonam and ceftazidime

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2010.00222.X

Biochemical characterization of laboratory mutants of extended-spectrum beta-lactamase TEM-60.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2010.00222.X

Clinical inhibitor-resistant mutants of the beta-lactamase TEM-1 at amino-acid position 69. Kinetic analysis and molecular modelling

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2010.00222.X

Inhibitor-resistant TEM beta-lactamases: phenotypic, genetic and biochemical characteristics

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2010.00222.X

A novel extended-spectrum TEM-type beta-lactamase, TEM-138, from Salmonella enterica serovar Infantis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2010.00222.X

Penicillinase Synthesis Controlled By Infectious R Factors In Enterobacteriaceae

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2010.00222.X

The purification and properties of a penicillinase whose synthesis is mediated by an R-factor in Escherichia coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2010.00222.X

Unexpected enzyme TEM-126: role of mutation Asp179Glu

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2010.00222.X

Missense meanderings in sequence space: a biophysical view of protein evolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2010.00222.X

SHV-49, a novel inhibitor-resistant beta-lactamase in a clinical isolate of Klebsiella pneumoniae

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2010.00222.X

Plasmid-Mediated Beta-Lactamase Production in Neisseria gonorrhoeae

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2010.00222.X

Molecular epidemiology of extended-spectrum beta-lactamases among Escherichia coli isolates collected in a Swedish hospital and its associated health care facilities from 2001 to 2006.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2010.00222.X

A novel complex mutant beta-lactamase, TEM-68, identified in a Klebsiella pneumoniae isolate from an outbreak of extended-spectrum beta-lactamase-producing Klebsiellae

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2010.00222.X

Kinetic studies on the inactivation of Escherichia coli RTEM β-lactamase by clavulanic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2010.00222.X

One-step random mutagenesis by error-prone rolling circle amplification

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2010.00222.X

RAISE: a simple and novel method of generating random insertion and deletion mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2010.00222.X

Detrimental effect of the combination of R164S with G238S in TEM-1 beta-lactamase on the extended-spectrum activity conferred by each single mutation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2010.00222.X

Evolution of extended-spectrum beta-lactamases by mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2010.00222.X

Potential role of phenotypic mutations in the evolution of protein expression and stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2010.00222.X

Directed selective pressure on a beta-lactamase to analyse molecular changes involved in development of enzyme function

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2010.00222.X

Predicting evolution by in vitro evolution requires determining evolutionary pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2010.00222.X

Structural perturbation and compensation by directed evolution at physiological temperature leads to thermostabilization of beta-lactamase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2010.00222.X

Nationwide study of Escherichia coli and Klebsiella pneumoniae producing extended-spectrum beta-lactamases in Spain

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2010.00222.X

Experimental evolution of gene duplicates in a bacterial plasmid model

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2010.00222.X

A natural polymorphism in beta-lactamase is a global suppressor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2010.00222.X

Effect of threonine-to-methionine substitution at position 265 on structure and function of TEM-1 beta-lactamase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2010.00222.X

Reversal of clavulanate resistance conferred by a Ser-244 mutant of TEM-1 beta-lactamase as a result of a second mutation (Arg to Ser at position 164) that enhances activity against ceftazidime

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2010.00222.X

Role of positive charge on the amino-terminal region of the signal peptide in protein secretion across the membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2010.00222.X

Crystal structure of Escherichia coli TEM1 beta-lactamase at 1.8 A resolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2010.00222.X

The net charge of the first 18 residues of the mature sequence affects protein translocation across the cytoplasmic membrane of gram-negative bacteria

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2010.00222.X

Increased folding stability of TEM-1 beta-lactamase by in vitro selection

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2010.00222.X

The prevalence of ESBL-producing E. coli and Klebsiella strains in the Copenhagen area of Denmark

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2010.00222.X

Extended-spectrum and inhibitor-resistant TEM-type beta-lactamases: mutations, specificity, and three-dimensional structure

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2010.00222.X

RNA mutagenesis yields highly diverse mRNA libraries for in vitro protein evolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2010.00222.X

Binding of cephalothin and cefotaxime to D-ala-D-ala-peptidase reveals a functional basis of a natural mutation in a low-affinity penicillin-binding protein and in extended-spectrum beta-lactamases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2010.00222.X

Identification of the beta lactamase R-TEM of Pseudomonas aeruginosa

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2010.00222.X

Promoters P3, Pa/Pb, P4, and P5 upstream from bla(TEM) genes and their relationship to beta-lactam resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2010.00222.X

CTX-M: changing the face of ESBLs in Europe

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2010.00222.X

Rapid in vivo evolution of a beta-lactamase using phagemids

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2010.00222.X

High diversity of extended-spectrum beta-lactamases among clinical isolates of Enterobacteriaceae from Portugal.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2010.00222.X

Genetic and Structural Characterization of an L201P Global Suppressor Substitution in TEM-1 β-Lactamase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2010.00222.X

Predicting antibiotic resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2010.00222.X

Contribution of mutant analysis to the understanding of enzyme catalysis: the case of class A beta-lactamases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2010.00222.X

Catalytic properties of class A beta-lactamases: efficiency and diversity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2010.00222.X

Plasmid-mediated β-lactamases of Gram-negative bacteria: properties and distribution

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2010.00222.X

Structural basis of extended spectrum TEM beta-lactamases. Crystallographic, kinetic, and mass spectrometric investigations of enzyme mutants.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2010.00222.X

Evolution and dissemination of beta-lactamases accelerated by generations of beta-lactam antibiotics

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2010.00222.X

Ampicillin-resistant Haemophilus influenzae type B possessing a TEM-type beta-lactamase but little permeability barrier to ampicillin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2010.00222.X

An ultrahigh resolution structure of TEM-1 beta-lactamase suggests a role for Glu166 as the general base in acylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2010.00222.X

Fitness trade-offs in blaTEM evolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2010.00222.X

Recombination and selection can remove blaTEM alleles from bacterial populations

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2010.00222.X

Ambler class A extended-spectrum beta-lactamase-producing Escherichia coli and Klebsiella spp. in Canadian hospitals

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2010.00222.X

TEM-89 beta-lactamase produced by a Proteus mirabilis clinical isolate: new complex mutant (CMT 3) with mutations in both TEM-59 (IRT-17) and TEM-3

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2010.00222.X

Evolutionary trajectories of beta-lactamase CTX-M-1 cluster enzymes: predicting antibiotic resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2010.00222.X

Predicting the emergence of antibiotic resistance by directed evolution and structural analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2010.00222.X

Protein evolution by codon-based random deletions

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2010.00222.X

Extended-spectrum beta-lactamases: structure and kinetic mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2010.00222.X

Occurrence of extended-spectrum beta-lactamases among chromosomal AmpC-producing Enterobacter cloacae, Citrobacter freundii, and Serratia marcescens in Korea and investigation of screening criteria

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2010.00222.X

Biochemical characterization of TEM-92 extended-spectrum beta-lactamase, a protein differing from TEM-52 in the signal peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2010.00222.X

Multiple substitutions at position 104 of beta-lactamase TEM-1: assessing the role of this residue in substrate specificity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2010.00222.X

Molecular characterization of a new plasmid-encoded SHV-type beta-lactamase (SHV-2 variant) conferring high-level cefotaxime resistance upon Klebsiella pneumoniae

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2010.00222.X

TEM beta-lactamase mutants hydrolysing third-generation cephalosporins. A kinetic and molecular modelling analysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2010.00222.X

Stability of TEM beta-lactamase mutants hydrolyzing third generation cephalosporins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2010.00222.X

TEM-109 (CMT-5), a natural complex mutant of TEM-1 beta-lactamase combining the amino acid substitutions of TEM-6 and TEM-33 (IRT-5).

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2010.00222.X

CMT-type beta-lactamase TEM-125, an emerging problem for extended-spectrum beta-lactamase detection

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2010.00222.X

TEM-158 (CMT-9), a new member of the CMT-type extended-spectrum beta-lactamases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2010.00222.X

Evolution of TEM-type enzymes: biochemical and genetic characterization of two new complex mutant TEM enzymes, TEM-151 and TEM-152, from a single patient

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2010.00222.X

Prevalence of clinical isolates of Escherichia coli and Klebsiella spp. producing multiple extended-spectrum beta-lactamases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2010.00222.X

The spread of CTX-M-type extended-spectrum beta-lactamases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2010.00222.X

Mass spectral kinetic study of acylation and deacylation during the hydrolysis of penicillins and cefotaxime by beta-lactamase TEM-1 and the G238S mutant.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2010.00222.X

Beta-lactams and beta-lactamase-inhibitors in current- or potential-clinical practice: a comprehensive update

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2010.00222.X

Investigating protein structural plasticity by surveying the consequence of an amino acid deletion from TEM-1 beta-lactamase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2010.00222.X

Functional characterization of the antibiotic resistance reservoir in the human microflora

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2010.00222.X

Substitution of lysine at position 104 or 240 of TEM-1pTZ18R beta-lactamase enhances the effect of serine-164 substitution on hydrolysis or affinity for cephalosporins and the monobactam aztreonam.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2010.00222.X

Rapid evolution of a protein in vitro by DNA shuffling

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2010.00222.X

X-ray structure of the Asn276Asp variant of the Escherichia coli TEM-1 beta-lactamase: direct observation of electrostatic modulation in resistance to inactivation by clavulanic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2010.00222.X

Structural consequences of the inhibitor-resistant Ser130Gly substitution in TEM beta-lactamase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2010.00222.X

Mutant TEM beta-lactamase producing resistance to ceftazidime, ampicillins, and beta-lactamase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2010.00222.X

Effects of Asp-179 mutations in TEMpUC19 beta-lactamase on susceptibility to beta-lactams

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2010.00222.X

Effects on substrate profile by mutational substitutions at positions 164 and 179 of the class A TEM(pUC19) beta-lactamase from Escherichia coli.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2010.00222.X

Evolution of an antibiotic resistance enzyme constrained by stability and activity trade-offs

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2010.00222.X

The structural bases of antibiotic resistance in the clinically derived mutant beta-lactamases TEM-30, TEM-32, and TEM-34

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2010.00222.X

Class A beta-lactamases--enzyme-inhibitor interactions and resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2010.00222.X

SHV-13, a novel extended-spectrum beta-lactamase, in Klebsiella pneumoniae isolates from patients in an intensive care unit in Amsterdam

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2010.00222.X

Survey of Enterobacteriaceae producing extended-spectrum beta-lactamases in a Slovak hospital: dominance of SHV-2a and characterization of TEM-132.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2010.00222.X

10.1111/J.1574-6976.2010.00222.X

21 January 2018

Identifiers

DOI

1 reference

22 August 2017

1 reference

PubMed ID

20412308