The scaffold protein p140Cap limits ERBB2-mediated breast cancer progression interfering with Rac GTPase-controlled circuitries (Q37710032)

22 August 2017

The scaffold protein p140Cap limits ERBB2-mediated breast cancer progression interfering with Rac GTPase-controlled circuitries (English)

1 reference

22 August 2017

9

1 reference

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Federica Cavallo

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Alessia Lamolinara

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Lorenzo Stramucci

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1 reference

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Enrico Moiso

18

1 reference

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1 June 2020

Paolo Provero

19

1 reference

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1 June 2020

Adriana Albini

20

1 reference

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1 June 2020

Anna Sapino

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1 reference

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1 June 2020

Stefano Confalonieri

27

1 reference

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Manuela Iezzi

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1 reference

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29

Paola Di Stefano

1 reference

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1 June 2020

30

Emilia Turco

1 reference

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1 June 2020

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Paola Defilippi

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Ludovica Verdun di Cantogno

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author name string

Silvia Grasso

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1 reference

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1 June 2020

Jennifer Chapelle

2

1 reference

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1 June 2020

Vincenzo Salemme

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Simona Aramu

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1 reference

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Isabella Russo

5

1 reference

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Nicoletta Vitale

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1 June 2020

Katiuscia Dallaglio

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1 reference

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1 June 2020

Augusto Amici

10

1 reference

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1 June 2020

Giorgia Centonze

11

1 reference

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1 June 2020

Nanaocha Sharma

12

1 reference

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1 June 2020

Serena Lunardi

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1 reference

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1 June 2020

Johan Staaf

22

1 reference

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1 June 2020

Pier Paolo Di Fiore

23

1 reference

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1 June 2020

Giovanni Bertalot

24

1 reference

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1 June 2020

Salvatore Pece

25

1 reference

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1 June 2020

Daniela Tosoni

26

1 reference

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1 June 2020

language of work or name

English

0 references

publication date

16 March 2017

1 reference

22 August 2017

Nature Communications

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28300085%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

volume

8

1 reference

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1 June 2020

page(s)

14797

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describes a project that uses

1 June 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC5357316/fullTextXML

inferred from PubMed Central ID database lookup

exact match

https://scigraph.springernature.com/pub.10.1038/ncomms14797

0 references

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Identification of two regions in the p140Cap adaptor protein that retain the ability to suppress tumor cell properties

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Rac-specific guanine nucleotide exchange factor DOCK1 is a critical regulator of HER2-mediated breast cancer metastasis

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23 August 2017

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23 August 2017

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p140Cap suppresses the invasive properties of highly metastatic MTLn3-EGFR cells via impaired cortactin phosphorylation.

23 August 2017

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23 August 2017

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Quantification and clinical relevance of gene amplification at chromosome 17q12-q21 in human epidermal growth factor receptor 2-amplified breast cancers

23 August 2017

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Identification of the Rac-GEF P-Rex1 as an essential mediator of ErbB signaling in breast cancer.

23 August 2017

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Integrin signalling adaptors: not only figurants in the cancer story

23 August 2017

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A Rac-Pak signaling pathway is essential for ErbB2-mediated transformation of human breast epithelial cancer cells

23 August 2017

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Genomic subtypes of breast cancer identified by array-comparative genomic hybridization display distinct molecular and clinical characteristics

23 August 2017

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p130Cas is an essential transducer element in ErbB2 transformation

23 August 2017

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Breast cancer precursors revisited: molecular features and progression pathways

23 August 2017

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High-resolution genomic and expression analyses of copy number alterations in HER2-amplified breast cancer

23 August 2017

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23 August 2017

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Apical polarity in three-dimensional culture systems: where to now?

23 August 2017

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23 August 2017

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23 August 2017

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23 August 2017

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p140Cap protein suppresses tumour cell properties, regulating Csk and Src kinase activity

23 August 2017

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23 August 2017

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23 August 2017

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23 August 2017

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23 August 2017

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Rational design and characterization of a Rac GTPase-specific small molecule inhibitor

23 August 2017

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Polarity and proliferation are controlled by distinct signaling pathways downstream of PI3-kinase in breast epithelial tumor cells

23 August 2017

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ErbB2, but not ErbB1, reinitiates proliferation and induces luminal repopulation in epithelial acini

23 August 2017

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Interleukin 12-mediated prevention of spontaneous mammary adenocarcinomas in two lines of Her-2/neu transgenic mice.

23 August 2017

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Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene

23 August 2017

1 reference

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Single-step induction of mammary adenocarcinoma in transgenic mice bearing the activated c-neu oncogene

23 August 2017

1 reference

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MicroRNA-346 functions as an oncogene in cutaneous squamous cell carcinoma

23 August 2017

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miR-211 promotes non-small cell lung cancer proliferation by targeting SRCIN1.

6 September 2017

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The relevance of EMT in breast cancer metastasis: Correlation or causality?

6 September 2017

1 reference

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miR-374a promotes cell proliferation, migration and invasion by targeting SRCIN1 in gastric cancer

6 September 2017

1 reference

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miR-150 promotes the proliferation and migration of lung cancer cells by targeting SRC kinase signalling inhibitor 1.

6 September 2017

1 reference

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The guanine nucleotide exchange factor Tiam1: a Janus-faced molecule in cellular signaling

6 September 2017

1 reference

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The HER2 amplicon includes several genes required for the growth and survival of HER2 positive breast cancer cells

6 September 2017

1 reference

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Extracellular matrix, integrins, and growth factors as tailors of the stem cell niche.

6 September 2017

1 reference

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Cell polarity as a regulator of cancer cell behavior plasticity

6 September 2017

1 reference

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Treatment of HER2-positive breast cancer: current status and future perspectives.

6 September 2017

1 reference

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Inactivation of Rac1 reduces Trastuzumab resistance in PTEN deficient and insulin-like growth factor I receptor overexpressing human breast cancer SKBR3 cells

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5357316

p140Cap dual regulation of E-cadherin/EGFR cross-talk and Ras signalling in tumour cell scatter and proliferation.

6 September 2017

1 reference

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Identification of subtypes in human epidermal growth factor receptor 2--positive breast cancer reveals a gene signature prognostic of outcome

14 September 2017

1 reference

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Analysis of activated GAPs and GEFs in cell lysates

23 June 2018

1 reference

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Amplification of a 280-Kilobase Core Region at the ERBB2 Locus Leads to Activation of Two Hypothetical Proteins in Breast Cancer

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5357316

p140Cap regulates memory and synaptic plasticity through Src-mediated and citron-N-mediated actin reorganization.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5357316

Alterations in the TOP2A and HER2 genes: association with adjuvant anthracycline sensitivity in human breast cancers.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5357316

Tiam1-deficiency impairs mammary tumor formation in MMTV-c-neu but not in MMTV-c-myc mice

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5357316

Beta 4 integrin amplifies ErbB2 signaling to promote mammary tumorigenesis.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5357316

p130Cas as a new regulator of mammary epithelial cell proliferation, survival, and HER2-neu oncogene-dependent breast tumorigenesis.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5357316

DNA vaccination against rat her-2/Neu p185 more effectively inhibits carcinogenesis than transplantable carcinomas in transgenic BALB/c mice.

1 September 2018

1 reference

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In vivo mapping of spontaneous mammary tumors in transgenic mice using MRI and ultrasonography

1 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNCOMMS14797

7 January 2021

inferred from DOI database lookup

Early and multifocal tumors in breast, salivary, Harderian and epididymal tissues developed in MMTY-Neu transgenic mice

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNCOMMS14797

7 January 2021

inferred from DOI database lookup

Proposal for standardized definitions for efficacy end points in adjuvant breast cancer trials: the STEEP system

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNCOMMS14797

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1038/NCOMMS14797

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28300085%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

1 June 2020

ADS bibcode

2017NatCo...814797G

0 references

0 references

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28300085%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

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