Leukocyte trafficking in primary immunodeficiencies (Q37352470)

19 August 2017

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title

Leukocyte trafficking in primary immunodeficiencies (English)

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19 August 2017

2

Raffaele Badolato

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19 August 2017

1

Luigi D Notarangelo

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19 August 2017

publication date

16 December 2008

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Journal of Leukocyte Biology

19 August 2017

published in

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19 August 2017

volume

85

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19 August 2017

issue

3

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19 August 2017

page(s)

335-343

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Homing and cellular traffic in lymph nodes

19 August 2017

cites work

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https://api.crossref.org/works/10.1189%2FJLB.0808474

In vivo imaging of leukocyte trafficking in blood vessels and tissues

21 January 2018

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https://api.crossref.org/works/10.1189%2FJLB.0808474

Immune cell migration in inflammation: present and future therapeutic targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0808474

Clonal deletion of thymocytes by circulating dendritic cells homing to the thymus

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0808474

Leukocyte-endothelial-cell interactions in leukocyte transmigration and the inflammatory response

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0808474

The many roles of chemokines and chemokine receptors in inflammation

21 January 2018

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https://api.crossref.org/works/10.1189%2FJLB.0808474

Leukocyte adhesion deficiency: an inherited defect in the Mac-1, LFA-1, and p150,95 glycoproteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0808474

Adhesion molecules--their role in health and disease

21 January 2018

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https://api.crossref.org/works/10.1189%2FJLB.0808474

21 January 2018

The leukocyte integrins

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https://api.crossref.org/works/10.1189%2FJLB.0808474

Leukocyte adhesion deficiency type 1 (LAD-1)/variant. A novel immunodeficiency syndrome characterized by dysfunctional beta2 integrins

21 January 2018

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https://api.crossref.org/works/10.1189%2FJLB.0808474

LAD-III, a novel group of leukocyte integrin activation deficiencies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0808474

Structural basis of integrin regulation and signaling

21 January 2018

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https://api.crossref.org/works/10.1189%2FJLB.0808474

Serum amyloid A is a chemoattractant: induction of migration, adhesion, and tissue infiltration of monocytes and polymorphonuclear leukocytes

21 January 2018

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https://api.crossref.org/works/10.1189%2FJLB.0808474

Src-family kinases mediate an outside-in signal necessary for beta2 integrins to achieve full activation and sustain firm adhesion of polymorphonuclear leucocytes tethered on E-selectin

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0808474

Reversion mutations in patients with leukocyte adhesion deficiency type-1 (LAD-1)

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0808474

Successful treatment of canine leukocyte adhesion deficiency by foamy virus vectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0808474

Potential genotoxicity from integration sites in CLAD dogs treated successfully with gammaretroviral vector-mediated gene therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0808474

Insights into leukocyte adhesion deficiency type 2 from a novel mutation in the GDP-fucose transporter gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0808474

Leukocyte trafficking in a mouse model for leukocyte adhesion deficiency II/congenital disorder of glycosylation IIc.

21 January 2018

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https://api.crossref.org/works/10.1189%2FJLB.0808474

Leukocyte adhesion deficiency II patients with a dual defect of the GDP-fucose transporter

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0808474

A LAD-III syndrome is associated with defective expression of the Rap-1 activator CalDAG-GEFI in lymphocytes, neutrophils, and platelets

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0808474

LAD-III, a leukocyte adhesion deficiency syndrome associated with defective Rap1 activation and impaired stabilization of integrin bonds

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0808474

Mice lacking the signaling molecule CalDAG-GEFI represent a model for leukocyte adhesion deficiency type III.

21 January 2018

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https://api.crossref.org/works/10.1189%2FJLB.0808474

LAD III versus LAD I variant

21 January 2018

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https://api.crossref.org/works/10.1189%2FJLB.0808474

CHRONIC IDIOPATHIC GRANULOCYTOPENIA.

21 January 2018

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https://api.crossref.org/works/10.1189%2FJLB.0808474

CXCR4 mutations in WHIM syndrome: a misguided immune system?

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0808474

Mutations in the chemokine receptor gene CXCR4 are associated with WHIM syndrome, a combined immunodeficiency disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0808474

Altered leukocyte response to CXCL12 in patients with warts hypogammaglobulinemia, infections, myelokathexis (WHIM) syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0808474

WHIM syndromes with different genetic anomalies are accounted for by impaired CXCR4 desensitization to CXCL12

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0808474

Enhanced function with decreased internalization of carboxy-terminus truncated CXCR4 responsible for WHIM syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0808474

HIV-1 Entry Cofactor: Functional cDNA Cloning of a Seven-Transmembrane, G Protein-Coupled Receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0808474

CXCR4-SDF-1 signalling, locomotion, chemotaxis and adhesion

21 January 2018

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https://api.crossref.org/works/10.1189%2FJLB.0808474

Defective lymphocyte chemotaxis in beta-arrestin2- and GRK6-deficient mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0808474

Phorbol esters and SDF-1 induce rapid endocytosis and down modulation of the chemokine receptor CXCR4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0808474

Trafficking of the HIV coreceptor CXCR4. Role of arrestins and identification of residues in the c-terminal tail that mediate receptor internalization

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0808474

GRK6 deficiency is associated with enhanced CXCR4-mediated neutrophil chemotaxis in vitro and impaired responsiveness to G-CSF in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0808474

Agonist-promoted ubiquitination of the G protein-coupled receptor CXCR4 mediates lysosomal sorting

21 January 2018

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https://api.crossref.org/works/10.1189%2FJLB.0808474

CXCR4 dimerization and beta-arrestin-mediated signaling account for the enhanced chemotaxis to CXCL12 in WHIM syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0808474

Molecular cloning and characterization of a murine pre-B-cell growth-stimulating factor/stromal cell-derived factor 1 receptor, a murine homolog of the human immunodeficiency virus 1 entry coreceptor fusin

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0808474

Impaired B-lymphopoiesis, myelopoiesis, and derailed cerebellar neuron migration in CXCR4- and SDF-1-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0808474

A role of CXC chemokine ligand 12/stromal cell-derived factor-1/pre-B cell growth stimulating factor and its receptor CXCR4 in fetal and adult T cell development in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0808474

WHIM syndrome myelokathexis reproduced in the NOD/SCID mouse xenotransplant model engrafted with healthy human stem cells transduced with C-terminus-truncated CXCR4

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0808474

Leukocyte circulation: one-way or round-trip? Lessons from primary immunodeficiency patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0808474

Mutations of the Wiskott-Aldrich Syndrome Protein (WASP): hotspots, effect on transcription, and translation and phenotype/genotype correlation

21 January 2018

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https://api.crossref.org/works/10.1189%2FJLB.0808474

WASP and the phenotypic range associated with deficiency

21 January 2018

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https://api.crossref.org/works/10.1189%2FJLB.0808474

Isolation of a novel gene mutated in Wiskott-Aldrich syndrome

21 January 2018

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https://api.crossref.org/works/10.1189%2FJLB.0808474

The WASP-WAVE protein network: connecting the membrane to the cytoskeleton

21 January 2018

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https://api.crossref.org/works/10.1189%2FJLB.0808474

Mechanisms of WASp-mediated hematologic and immunologic disease.

21 January 2018

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https://api.crossref.org/works/10.1189%2FJLB.0808474

Autoinhibition and activation mechanisms of the Wiskott-Aldrich syndrome protein

21 January 2018

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https://api.crossref.org/works/10.1189%2FJLB.0808474

A two-state allosteric model for autoinhibition rationalizes WASP signal integration and targeting

21 January 2018

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https://api.crossref.org/works/10.1189%2FJLB.0808474

Integration of multiple signals through cooperative regulation of the N-WASP-Arp2/3 complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0808474

Activation by Cdc42 and PIP(2) of Wiskott-Aldrich syndrome protein (WASp) stimulates actin nucleation by Arp2/3 complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0808474

Constitutively activating mutation in WASP causes X-linked severe congenital neutropenia

21 January 2018

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https://api.crossref.org/works/10.1189%2FJLB.0808474

Unregulated actin polymerization by WASp causes defects of mitosis and cytokinesis in X-linked neutropenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0808474

Phosphorylation of tyrosine 291 enhances the ability of WASp to stimulate actin polymerization and filopodium formation. Wiskott-Aldrich Syndrome protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0808474

WIP, a protein associated with wiskott-aldrich syndrome protein, induces actin polymerization and redistribution in lymphoid cells

21 January 2018

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https://api.crossref.org/works/10.1189%2FJLB.0808474

WIP is a chaperone for Wiskott-Aldrich syndrome protein (WASP).

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0808474

A multiinstitutional survey of the Wiskott-Aldrich syndrome.

21 January 2018

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https://api.crossref.org/works/10.1189%2FJLB.0808474

Cell adhesion molecules and actin cytoskeleton at immune synapses and kinapses

21 January 2018

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https://api.crossref.org/works/10.1189%2FJLB.0808474

Regulation of actin assembly associated with protrusion and adhesion in cell migration

21 January 2018

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https://api.crossref.org/works/10.1189%2FJLB.0808474

21 January 2018

Podosomes at a glance

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https://api.crossref.org/works/10.1189%2FJLB.0808474

Requirement for a complex of Wiskott-Aldrich syndrome protein (WASP) with WASP interacting protein in podosome formation in macrophages

21 January 2018

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https://api.crossref.org/works/10.1189%2FJLB.0808474

Chemotaxis of macrophages is abolished in the Wiskott-Aldrich syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0808474

Impaired dendritic-cell homing in vivo in the absence of Wiskott-Aldrich syndrome protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0808474

Retroviral WASP gene transfer into human hematopoietic stem cells reconstitutes the actin cytoskeleton in myeloid progeny cells differentiated in vitro.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0808474

Improvement of migratory defects in a murine model of Wiskott-Aldrich syndrome gene therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0808474

The actin cytoskeleton in T cell activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0808474

Mechanism of recruitment of WASP to the immunological synapse and of its activation following TCR ligation

21 January 2018

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https://api.crossref.org/works/10.1189%2FJLB.0808474

Dynamic molecular interactions linking the T cell antigen receptor to the actin cytoskeleton.

21 January 2018

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https://api.crossref.org/works/10.1189%2FJLB.0808474

Wiskott-Aldrich syndrome protein regulates lipid raft dynamics during immunological synapse formation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0808474

Early deficit of lymphocytes in Wiskott-Aldrich syndrome: possible role of WASP in human lymphocyte maturation

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0808474

WASp verprolin homology, cofilin homology, and acidic region domain-mediated actin polymerization is required for T cell development

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0808474

Wiskott Aldrich syndrome protein (WASP) and N-WASP are critical for T cell development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0808474

WASP deficiency leads to global defects of directed leukocyte migration in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0808474

The interaction between Cdc42 and WASP is required for SDF-1-induced T-lymphocyte chemotaxis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0808474

Lentiviral vector-mediated gene transfer in T cells from Wiskott-Aldrich syndrome patients leads to functional correction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0808474

Gene therapy for Wiskott-Aldrich syndrome: rescue of T-cell signaling and amelioration of colitis upon transplantation of retrovirally transduced hematopoietic stem cells in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0808474

A lentiviral vector encoding the human Wiskott-Aldrich syndrome protein corrects immune and cytoskeletal defects in WASP knockout mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0808474

Efficacy of gene therapy for Wiskott-Aldrich syndrome using a WAS promoter/cDNA-containing lentiviral vector and nonlethal irradiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0808474

Lentiviral vectors targeting WASp expression to hematopoietic cells, efficiently transduce and correct cells from WAS patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0808474

Wiskott-Aldrich syndrome protein deficiency leads to reduced B-cell adhesion, migration, and homing, and a delayed humoral immune response

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0808474

WASP confers selective advantage for specific hematopoietic cell populations and serves a unique role in marginal zone B-cell homeostasis and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0808474

Follicular shuttling of marginal zone B cells facilitates antigen transport

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0808474

The spleen in the Wiskott-Aldrich syndrome: histopathologic abnormalities of the white pulp correlate with the clinical phenotype of the disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0808474

A defect in hematopoietic stem cell migration explains the nonrandom X-chromosome inactivation in carriers of Wiskott-Aldrich syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0808474

Mechanisms of WHIM syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0808474

21 January 2018

Identifiers

DOI

10.1189/JLB.0808474

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19 August 2017

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