The Notch signaling inhibitor DAPT down-regulates cdk5 activity and modulates the distribution of neuronal cytoskeletal proteins (Q37074066)

18 August 2017

The Notch signaling inhibitor DAPT down-regulates cdk5 activity and modulates the distribution of neuronal cytoskeletal proteins (English)

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18 August 2017

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Jyotshnabala Kanungo

1

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18 August 2017

Ya-Li Zheng

series ordinal

2

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18 August 2017

Niranjana D Amin

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3

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18 August 2017

Harish C Pant

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4

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18 August 2017

language of work or name

English

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publication date

4 July 2008

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Journal of Neurochemistry

18 August 2017

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18 August 2017

106

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18 August 2017

5

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18 August 2017

2236-2248

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describes a project that uses

18 August 2017

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2631422/fullTextXML

inferred from PubMed Central ID database lookup

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29 September 2017

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29 September 2017

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29 September 2017

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27 June 2018

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27 June 2018

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Cyclin-dependent kinase 5 increases perikaryal neurofilament phosphorylation and inhibits neurofilament axonal transport in response to oxidative stress

4 September 2018

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Cdk5 regulates axonal transport and phosphorylation of neurofilaments in cultured neurons

4 September 2018

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Decreased cyclin-dependent kinase 5 (cdk5) activity is accompanied by redistribution of cdk5 and cytoskeletal proteins and increased cytoskeletal protein phosphorylation in p35 null mice.

4 September 2018

1 reference

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Gamma-secretase/presenilin inhibitors for Alzheimer's disease phenocopy Notch mutations in Drosophila.

4 September 2018

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A peptide derived from cyclin-dependent kinase activator (p35) specifically inhibits Cdk5 activity and phosphorylation of tau protein in transfected cells

4 September 2018

1 reference

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Deregulation of cdk5, hyperphosphorylation, and cytoskeletal pathology in the Niemann-Pick type C murine model.

4 September 2018

1 reference

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Phosphorylation of MEK1 by cdk5/p35 down-regulates the mitogen-activated protein kinase pathway

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2631422

Neuronal cyclin-dependent kinase 5 activity is critical for survival.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2631422

Functional gamma-secretase inhibitors reduce beta-amyloid peptide levels in brain

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2631422

Mitogen-activated protein kinases (Erk1,2) phosphorylate Lys-Ser-Pro (KSP) repeats in neurofilament proteins NF-H and NF-M.

4 September 2018

1 reference

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The activity of neurogenin1 is controlled by local cues in the zebrafish embryo.

4 September 2018

1 reference

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A ligand-induced extracellular cleavage regulates gamma-secretase-like proteolytic activation of Notch1

4 September 2018

1 reference

12 December 2020

Tau protein isoforms, phosphorylation and role in neurodegenerative disorders11These authors contributed equally to this work

1 reference

12 December 2020

Fas engagement induces neurite growth through ERK activation and p35 upregulation

1 reference

12 December 2020

Jagged1 protein enhances the differentiation of mesenchymal stem cells into cardiomyocytes

1 reference

12 December 2020

10.1111/J.1471-4159.2008.05551.X

Identifiers

DOI

1 reference

18 August 2017

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18 August 2017

PubMed publication ID

18662245

1 reference